GenBank-Updates@genbank.bio.net (03/27/91)
LOCUS HUMNT3A 1029 bp ds-DNA PRI 27-MAR-1991
DEFINITION Human neurotrophin-3 gene, complete cds, from 1.8 kb HindIII
fragment.
ACCESSION M61180
KEYWORDS neurotrophic factor; neurotrophin-3.
SOURCE Human DNA, clone phi-hN(G1).
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1029)
AUTHORS Maisonpierre,P.C., Le Beau,M.M., Espinosa,R., Ip,N.Y.,
Belluscio,L., de la Monte,S.M., Squinto,S., Furth,M.E. and
Yancopoulos,G.D.
TITLE Human and rat BDNF and NT-3: Gene structures, distributions and
chromosomal localizations
JOURNAL Unpublished (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 116..889
/product="neurotrophin-3"
/gene="NT-3"
/codon_start=116
mat_peptide 530..886
/product="brain-derived neurotrophic factor"
/gene="BDNF"
/codon_start=530
BASE COUNT 289 a 248 c 251 g 241 t
ORIGIN Chromosome 12p13.
1 cctcacaggg ctactcagcc tcaggtagct ggtgccagaa taacacagac tcagctgcca
61 gagcctgctc ttaacacctg tgtttccttt tcagatctta caggtgaaca aggtgatgtc
121 catcttgttt tatgtgatat ttctcgctta tctccgtggc atccaaggta acaacatgga
181 tcaaaggagt ttgccagaag actcgctcaa ttccctcatt attaagctga tccaggcaga
241 tattttgaaa aacaagctct ccaagcagat ggtggacgtt aaggaaaatt accagagcac
301 cctgcccaaa gctgaggctc cccgagagcc ggagcgggga gggcccgcca agtcagcatt
361 ccagccagtg attgcaatgg acaccgaact gctgcgacaa cagagacgct acaactcacc
421 gcgggtcctg ctgagcgaca gcaccccctt ggagcccccg cccttgtatc tcatggagga
481 ttacgtgggc agccccgtgg tggcgaacag aacatcacgg cggaaacggt acgcggagca
541 taagagtcac cgaggggagt actcggtatg tgacagtgag agtctgtggg tgaccgacaa
601 gtcatcggcc atcgacattc ggggacacca ggtcacggtg ctgggggaga tcaaaacggg
661 caactctccc gtcaaacaat atttttatga aacgcgatgt aaggaagcca ggccggtcaa
721 aaacggttgc aggggtattg atgataaaca ctggaactct cagtgcaaaa catcccaaac
781 ctacgtccga gcactgactt cagagaacaa taaactcgtg ggctggcggt ggatacggat
841 agacacgtcc tgtgtgtgtg ccttgtcgag aaaaatcgga agaacatgaa ttggcatctc
901 tccccatata taaattatta ctttaaatta tatgatatgc atgtagcata taaatgttta
961 tattgttttt atatattata agttgacctt tatttattaa acttcagcaa ccctacagta
1021 tataagctt
//