[bionet.molbio.genbank.updates] Human IgH chain

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFA     426 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62723
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-TS1.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..426
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..57
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     58..426
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=58
                     /partial
BASE COUNT       93 a    109 c    134 g     90 t
ORIGIN      Chromosome 14.
        1 atggactgga cctggaggat cctctttgtg gtggcagcag ctacaggtgt ccagtcccag
       61 gtgcagctgg tgcagtctgg ggctgaggtg aagaagcctg ggtcctcggt gaaggtctcc
      121 tgcaaggctt ctggaggcac cttcagcacc tatgctatca gctgggtgcg acaggcccct
      181 ggacaagggc ctgagtccat gggagggatc acccctatgt ttggtagagc aaactacgca
      241 cagaagttcc agggcagagt cacgattact gcggacgaat ccacgagcac agcctacatg
      301 gagctgagca gcctgagatc tgaggactcg gccgtatatt tctgtgcgag agaggaccca
      361 tacggtgact acgtcgcgaa tccttttgat atctggggcc aagggacaat ggtcaccgtc
      421 tcttca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFB     375 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62724
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-TS3.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..375
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..15
                     /gene="IgH"
                     /codon_start=1
                     /partial
     mat_peptide     16..375
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=16
                     /partial
BASE COUNT       91 a     96 c    103 g     85 t
ORIGIN      Chromosome 14.
        1 ataagtgccc actcccaggt gcagctggtg caatctgggt ctgagttgaa gaagcctggg
       61 gcctcagtga aggtttcctg caaggcttct ggatacacct tcactagcta tgctatgaat
      121 tgggtgcgac aggcccctgg acaagggctt gagtggatgg gatggatcaa caccaacact
      181 gggaacccaa cgtatgccca gggcttcaca ggacggtttg tcttctcctt ggacacctct
      241 gtcagcacgg catatctgca gatcagcagc ctaaaggctg acgacactgc cgtgtattac
      301 tgtgcgagag aagatagcaa tggctacaaa atatttgact actgggacca gggaaccctg
      361 gtcatcgtct cctca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFC     447 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62726
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-SJ2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..447
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..60
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     61..447
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=61
                     /partial
BASE COUNT       93 a    107 c    136 g    111 t
ORIGIN      Chromosome 14.
        1 atggagtttg ggctgagctg ggttttcctc gttgctcttt taagaggtgg tgtccagtgt
       61 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc
      121 tcctgtgcag cctctggatt caccttcagt agctatgcta tgcactgggt ccgccaggct
      181 ccaggcaagg ggctggagtg ggtggcagtt atatcatatg atggaagcaa taaatactac
      241 gcagactccg tgaagggccg attcaccatc tccagagaca attccaagaa cacgctgtct
      301 ctgcaaatga acagcctgag agctgaggac accgctgtgt attactgtgc gagaggccgg
      361 ttttgtagtg gtggtagctg ctactcttac tactactact actacatgga cgtctggggc
      421 aaagggacca cggtcaccgt ctcctca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFD     447 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62728
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-SJ1.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..447
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..60
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     61..447
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=61
                     /partial
BASE COUNT       99 a     95 c    137 g    116 t
ORIGIN      Chromosome 14.
        1 atggagtttg ggctgagctg ggttttcctc gttgctcttt taagaggtgg tgtccagtgt
       61 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc
      121 tcctgtgcag cctctggatt cagtttcagt agttatggca tgcactgggt ccgccagtgt
      181 ccaggcaagg ggctggagtg ggtggcagtt atatcagatg acggaagtaa taaatattat
      241 gcagactccg tgaagggccg attcaccatc tccagagaca attccaagaa aacgctgtat
      301 ctgcaaatgg acagcctgag aactgaggac acggctgtgt attactgtgc gaaaggggtt
      361 tattgtagta gtagtagttg ctattcttac tactactacc actacatgga cgtctggggc
      421 aaagggacca cggtcaccgt ctcctca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFE     440 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62729
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-TS2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..440
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..60
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     61..440
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=61
                     /partial
BASE COUNT       89 a     98 c    136 g    117 t
ORIGIN      Chromosome 14.
        1 atggagtttg ggctgagctg ggttttcctc gttgctcttt taagaggtgg tgtccagtgt
       61 caggtgcagc tggtggagtc tgggggaggc gtggtccagc cggggaggtc cctgagactc
      121 tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt ccgccaggct
      181 ccaggcaagg ggctggagtg ggtggcagtt atatcatatg atggaagtaa tgaatacttt
      241 gctgactccg tgaagggccg attcaccatc tccagagaca attccaacaa cacgctgtat
      301 atgcaaatga acagcctgag agctgaggac acggctgtct attactgtgc gagagatcgt
      361 gtggccgtat atatgccagt gtttttttca ttgactcttt tgatatctgg ggccaaggga
      421 caggggtcac cgtctcctca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFF     426 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62731
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-KL1.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..426
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..60
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     61..426
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=61
                     /partial
BASE COUNT       91 a    100 c    130 g    105 t
ORIGIN      Chromosome 14.
        1 atggagtttg ggctgagctg gctttttctt gtggctattt taaaaggtgg tgtccagtgt
       61 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc cgggggggtc cctgagactc
      121 tcctgtgcag cctctggatt cacctttagt tcatatgcca tgagttgggt ccgccaggct
      181 ccagggaagg ggctggagtg ggtctcagca attagtgata acggtggaat aacatactac
      241 acagactacg tgaagggccg gttcaccatc tccagagaca attccaagaa ccccctgtat
      301 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaaaaaattg
      361 aggtccgggc tcgtcccgta ctactttgac ttctggggca ggggaaccct ggtcaccgtc
      421 tcctca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMIGHRFG     351 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA V-region.
ACCESSION   M62737
KEYWORDS    V-region; immunoglobulin heavy chain;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone GL-SJ2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..351
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..57
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     58..351
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=58
                     /partial
BASE COUNT       77 a     81 c    107 g     86 t
ORIGIN      Chromosome 14.
        1 atggagtttg ggctgagctg ggttttcctc gttgctcttt taagaggtgt ccagtgtcag
       61 gtgcagctgg tggactctgg gggaggcgtg gtccagcctg ggaggtccct gagactctcc
      121 tgtgcagcct ctgcattcac cttcagtagc tatgctatgc actgggtccg ccaggctcca
      181 ggcaaggggc tagagtgggt ggcagttata tcatatgatg gaagtaataa atactacgca
      241 gactccgtga agggccgatt caccatctcc agagacaatt ccaagaacac gctgtatctg
      301 caaatgaaca gcctgagagc tgaggacacg gctgtgtatt actgtgcgag a
//