GenBank-Updates@genbank.bio.net (03/28/91)
LOCUS HUMPGDF 1790 bp ds-DNA PRI 28-MAR-1991
DEFINITION Human platelet-derived growth factor A-chain (PDGF) gene, 5' end
and promoter region.
ACCESSION M59423
KEYWORDS platelet-derived growth factor A-chain.
SOURCE Human leukocyte DNA, clone B2.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1790)
AUTHORS Takimoto,Y., Wang,Z., Kobler,K. and Deuel,T.F.
TITLE Promoter region of the human platelet-derived growth factor A-chain
gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88, 1686-1690 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
promoter 1..1787
/gene="PDGF"
/partial
misc_feature 851..905
/note="GC signal"
/gene="PDGF"
/partial
TATA_signal 906..910
/gene="PDGF"
/partial
CDS 1782..1790
/product="platelet-derived growth factor A-chain"
/gene="PDGF"
/codon_start=1782
/partial
BASE COUNT 195 a 676 c 687 g 232 t
ORIGIN
1 agggaggcga aatccatcca gcccagcgca ccgccctttc tcggcgtggg agccgtctag
61 ccacgctcag acctcggcct ccgcgcgcgt tcctccccca tcgcgctctg actgcgcctc
121 ggccggaggt gctctgtgcg ccccacggat ccgacgcggg aggctcagaa cccgggggac
181 cctcaccggt ggctcctttc ccttccatcc cctcgacttc ccggctcagg cgcggcccct
241 tcggcgcggg agtgggggac tggggggcgc ggggtcccag ggtggggacg aggcggctgc
301 aggccctttc cccgactgga gctcgctccc aagtggaaat gtgggtggag ggtcctcatt
361 cagatgcccc aggcctcgga tcctgggcgg gggcgcgtgg cagccgcagg tgagtgcccc
421 aaacccgccc ccctccttcc ccaaagactg actccccctc cttttatgga gagaggaagg
481 ctggggcctg gatccgaacc gtggagagcg gccggagcgc gggcggggcg gggacggctc
541 tctggccctt tttggcgcaa gctctgggcg ctgcgctgcc gcgtgggccc gagagaggcg
601 agccgcgacg gcgcttctgc ggcggcctcc tccctcccca cccggtgccg cagattgcag
661 ctggcactgg agggtgggca agctcgaggg aggggcgcgg agcgcgcgga gcgcgcgggg
721 ctttgatgga tttagctgct tgcgcgagcg cgtgtgtgct ccctgccgcg gcggcggcgc
781 ccgggccctg ccgggtccgc acgaacccct agcgcttccg aggtgcgggt cccaggcccg
841 gaatccgggg aggcgggggg gggggggcgg gggcgggggc gggggagggg cgcggcggcg
901 gcggctataa ccctctcccc gccgccggcc ggctccacac gcgcgccctg cggagcccgc
961 ccaactccgg cgagccggcc tgcgcctact cctcctcctc ctctcccggc ggcggctgcg
1021 gcggaggcgc cgactcggcc ttgcgccgcc ctcaggcccg cgcggccggc gcagcgaggc
1081 cccgggcggc gggtggtggc tgccaggcgg ctcggccggc cgcgcgctgc ccggccccgg
1141 ccgagcggag ggcggacgcc ggcgccggga gccgagggcc gccgcggagg gggtgctgcg
1201 gccgcgctgt gcccggccgg gcggcggctg caagaggagg ccggaggcga gcgcggggcc
1261 ggcggtgggc gcgcagggcg gctcgcagct cgcagccggg gccgggccag gcgtccaggc
1321 aggtgatcgg tgtggcggcg gcggcggcgg cggccccaga ctccctccgg agttcttctt
1381 cggggctcga tgtccgcaaa tatggcagaa tgtaccggcc gggtcgctcc tgaagccagc
1441 gcggggagcg agcgcggcgg cggccagcac cgggaacgca ccgaggaaga agcccagccc
1501 ccgccctccg ccccttccgt ccccaccccc taccggcggc ccaggaggct ccccgcgctg
1561 gcgcgcactc cctgtttctc ctcctcctgg ctggcgctgc ctgcctctcc gcactcactg
1621 ctcgcgccgg gcggctccgc cagctccgtg ctccccgcgc caccctcctc cgggccgcgc
1681 tccctaaggg atggtactga atttcgccgc cacaggagac cggctggagc gccgccccgc
1741 ggcctcgcct ctcctccgag cagccagcgc ctcgggacgc gatgaggacc
//