GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMMYLRARA 748 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human t(15:17) myl-RARalpha fusion gene.
ACCESSION M61110
KEYWORDS translocation breakpoint.
SOURCE Human (patient AML-P1) adult leukemic blastocyte DNA, clone R13A.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 748)
AUTHORS Alcalay,M., Zangrilli,D., Pandolfi,P.P., Longo,L., Mencarelli,A.,
Giacomucci,A., Rocchi,M., Biondi,A., Rambaldi,A., Lo Coco,F.,
Diverio,D., Donti,E., Grignani,F. and Pelicci,P.G.
TITLE Translocation breakpoint of acute promyelocytic leukemia lies
within the retinoic acid receptor alpha locus
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88, 1977-1981 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
misc_feature 1..201
/note="chromosome 15 DNA"
misc_feature 202..748
/note="chromosome 17 DNA"
exon 574..722
/number=2
/gene="RAR-alpha"
BASE COUNT 159 a 195 c 218 g 176 t
ORIGIN
1 ttctatgaac actgccaggc aggtagtcag ttgggcagga gttgaggtcg acccagagga
61 atctggaaca agagagttct aaggatctgc ttcacccaga gtacagcttt gttcctcatt
121 ctgactgagc cctagccttg gtcacacact gagcactgac tgatattcct tacccacaaa
181 tgctattggt aatcgatggg ttccttccta actcgggggg agaacggggc caggccccca
241 ggggcaggag ctttagaatc agggtgaccc ccacccctac tccccaagca cagtcacggc
301 acacatacaa atgtgatggt ttatcattgt atctttgtgg ttttgaaggt gggggtccta
361 ggagtccaga ggagtgatgg ggtgctggag gcttcattgg cagcctcctg ccctgagtct
421 ggctggggag tcccagtttt cttaagactt gaatcctgcc agcagtggtg aggctgggag
481 aggctcttag gagggacggt gaggcagggt ggagcttggt actaaggatg gcgacctagg
541 tctctaactg cccctcccct cttctctctc tagccattga gacccagagc agcagttctg
601 aagagatagt gcccagccct ccctcgccac cccctctacc ccgcatctac aagccttgct
661 ttgtctgtca ggacaagtcc tcaggctacc actatggggt cagcgcctgt gagggctgca
721 aggtgagttg aaggggtcat tgggaagg
//