GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT01 1949 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 1.
ACCESSION M61834
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 1 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1949)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
BASE COUNT 499 a 484 c 430 g 536 t
ORIGIN Chromosome 2.
1 aagatactta ttataggaag aggagggggg agggtgaagg aatttgcaag tttttcatag
61 atgtttctat attgtttgaa tctcttacaa aatatgttca gcatattttt aaagagaaaa
121 tttggggcaa aatacttatt tttgtattat gtaaacaaat tttaaaataa tgtgtggctg
181 ggtgcgctgg ctcacacctg taatcccaac actttaggag gctgaggcaa gaggattgct
241 tgagcccagg agttcaagac cagcctgggt gacatggcaa aactccatct ctactaaaaa
301 tacaaaaaat tagccagtcg tggtggcgca cacctatggt cccacctacc caggatgctg
361 agatgggagg atcacttgag cccaggaagt caaggctgca ggaagctgtg atcgcaccac
421 tgcactccca cctgggcaac agagtgagac ccggtcacca aaaaacaaaa aaaacaaaaa
481 aaattggtaa tcgttttctt cagacatttt ccgggttcct ctgcttaact tgtataggaa
541 gtctgaggtt tttgtgttgg tctttacctt tttttttttt tttttttttt ttaagatgga
601 gtctcattct gttgcccagg ctggagtgca gtggcatgat cttggctcct gcaacctccg
661 cctcctgggt tcaagtgatt ctcctgcctc agcctcctga gtagccggga ctacaggcgc
721 atgccacgat gcctggctaa ttttttgtat ttttagtaga gatggggttt caccatgtta
781 gctaggacgg tctcgatctc ctgacctcgt gatccgccca cctcggcctc ccaaagtgct
841 ggaattacag gtgtgagcca ccacgcccgg ccctgatctt tacattttta aatattgcat
901 tagtgaaccg tgtactgatt ttgtgatcat agataaccca gttaaatatt aagtcttaat
961 tatcacttag tattttacaa cctcagttgc agttataaag taagggttcc acatacctcc
1021 taacagttcc tagaaaatgg agctgtcttg gcatgtagtc tttattgccc tgctaagttt
1081 ttcatgctgg gggtcagact gggagtctga tagaaatttc atttccaccg ctggtcctct
1141 aaccaatgac ttgctgcaca acctgagtgg tctcctggga gaccagagtt ctaactttgt
1201 agcaggggac aaagacatgt atgtttgtca ccagccactg cccactttcc tgccagaata
1261 cttcagcagt ctccatgcca gtcagatcac ccattataag gtatttctgt catgggcaca
1321 gctcctccca gcaggaagca cccagaatcc agacgagaaa acagtgcagt gctaccggcg
1381 actcctcaag gccctcaaga ctgcacggct tcagcccatg gtcatcctgc accaccagac
1441 cctccctgcc agcaccctcc ggagaaccga agcctttgct gacctcttcg ccgactatgc
1501 cacattcgcc ttccactcct tcggggacct agttgggatc tggttcacct tcagtgactt
1561 ggaggaagtg atcaaggagc ttccccacca ggaatcaaga gcgtcacaac tccagaccct
1621 cagtgatgcc cacagaaaag cctatgagat ttaccacgaa agctatgctt ttcagggtga
1681 gtacacattg acctgatggt gacccctcgg caaccttcat cacacacctt ccccatcctc
1741 cttagagcag attcgacatt tctcccaact caccttcagc agtcctctta tgtctgtgca
1801 tagggagaaa ttaatattgt aaattgattt cccactggcg ataggaaggg gtagctaaca
1861 tggcaaaaca ctcagcattt cctttgaaaa atatctttgc atgtcacgcc tgtaatccta
1921 gcactttggg aggccgaggt gggcggatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT02 1121 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 2.
ACCESSION M61835
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 2 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1121)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 479..558
/number=2
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 309 a 247 c 273 g 292 t
ORIGIN Chromosome 2.
1 gatcgagact atctggctaa cacggtgaaa ccccatctct actaaaaata caaaaaatta
61 gccgggcgtg gtggtgggca cctgtagtcc cagctactca ggaggctgag gcaggagaat
121 ggcattaacc caggaggcgg agtttcagtg agccgagatg gcacgactgc actccagcct
181 gggcgacgga gcgagactcc gtctcaaaaa aaaaaaaaaa aaaaaaagaa gtttaggaag
241 gagttctctc cttgccaact ctccaactgc tctgcatttc atagtcctga ttttcacaaa
301 acactctcta aaggaacatt atttttttaa gccaccttgt cttctaaaat ctttcagcta
361 gagtaaagtc atttggatga tttcttcagg tccataggaa atgaatcccc cagtggtttc
421 cacagtcaga gcctcctgcc ctcgctcacc tgctgttcgt gtctctggtt ggtttcaggc
481 ggaaaactct ctattgtcct gcgagctgaa gatatcccgg agctcctgct agaaccaccc
541 atatctgcgc ttgcccaggt gacagcagcc caaaaatata cctgtaacat ctgaggagag
601 tttgatttta attttttaaa aacaagagaa gttttggtct attggtttga catttctgta
661 aatgcctcag aatgagtggt gtatgttctc caggttcata attaccttaa aaacaaaatc
721 ttgaagctgc agctcctgct tggtcaagtg tcagcttccc tgcaggaaga agccacttgc
781 ctctgctggc tctgattttt gagtccaaaa tagcttatag gataagagat gagattatgg
841 caaaacaggt actagggtaa aggggttttt caaaaatgtg cacctggcca aacacggtgg
901 ctcacttctg taatcccagc actttgggag gcggagatgg gagggttgtt tgagccagga
961 gtttgagacc agcctgggca acatggcaaa actccttctt tgctaaaaat acaaaaatta
1021 gcaaggcatg gtgatgcatg cctgtagttc cagctgctcg ggaggatgag gtgggaggat
1081 tgcttgagcc ctggaggtca aggctgcagt gaactgtgat c
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT03 481 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 3.
ACCESSION M61836
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 3 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 481)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 161..244
/number=3
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 134 a 90 c 107 g 150 t
ORIGIN Chromosome 2.
1 acacactttc tcattccatc tccatctttt cctttggaaa atcctgcttt ggaatatttg
61 gtttagtgat aaggggagaa acaaaaaagc gtacttctga gaggctgtta gtcttgacag
121 tgcttaggtt ctaatgaccc tatttaacta ctattttcag gacacggtcg atttcctctc
181 tcttgatttg tcttatgaat gccaaaatga ggcaagtctg cggcagaagc tgagtaaatt
241 gcaggtaatt tgagcccttt tccacattaa tgatgaatgc agcgaaggtt tcagagagca
301 gattagacat ttaatgcttt ggctactgca taaactgaac ttccatcaac agcagagacc
361 ggctgagttg tgtctgggga gatttccatt gcaagcatcc ctagagaaca tcggatgtta
421 ggcagtcttt cctagaaggg atacaagggt tagcttgtta aggtgaatat ttatatagat
481 c
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT04 824 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 4.
ACCESSION M61837
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 4 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 824)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 172..274
/number=4
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 189 a 217 c 178 g 240 t
ORIGIN Chromosome 2.
1 gatctttctc cttcagagtc tagagttgac tcctttaatt aactgagata cttagaggtc
61 atttccaaag ccagagtaag tgccacagct tctcatcttg aaactctgtc cctgttatca
121 agatgctttc caggaggctt cagttcactt gctggtcctt ctctttttca gaccattgag
181 ccaaaagtga aagttttcat cttcaaccta aaactcccag actgcccctc caccatgaag
241 aacccagcca gtctgctctt cagccttttt gaaggtgagt gggccattgc tgaagaggtt
301 ttgagtgaca tctggtgcac tggtgtgcta ggtagcagtc ttgaaagtcc ggggttccaa
361 tgggaggagg agcatgggag gaagactagt ctaaaagccc accccagact gggttagtgt
421 actatgcctt cctactgatg gtcccttgca accatccccc attgacccaa gaaagaggag
481 aggttcgaca caaggatgcc ttcttatgga cataaagata gttaggcctc agctgtgagt
541 tgtaagcatg gaaaatcatc tttgcctcct tttattacct ctccctccaa ggtctctcat
601 ctctgctcct cttggcaggg ctttcctctg cccgtctctc tccagccagc cctctccact
661 tacccttgtt ccatgtcccc attatctcag tttgcacatg gccctggtgg gtacctgacc
721 aagatgctaa gaactttcaa gtgtaggact cagctcaagg gccatcttcc tagtgtctct
781 tagttcaaat tcttgaaagt gaatctgatt gttggccatg gatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT05 662 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 5.
ACCESSION M61838
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 5 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 662)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 147..225
/number=5
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 185 a 126 c 153 g 198 t
ORIGIN Chromosome 2.
1 ggttagccca tggtattttc caaaggggct tggaaccact gcttggagtt tgggtgtgtc
61 gtatgagcga ggaaaactgt tgatttcaga cttgcatgtt cttagttggc atttacatag
121 agttaattca atttcttctc ttacagccat aaataaagac caagtgctca ccattgggtt
181 tgatattaat gagtttctga gttgttcatc aagttccaag aaaaggtaat gtcaggttgc
241 ctattgaact atcaataact gatatttgta gaatacctct gtttctttta catgtataat
301 cttataggac tgttgtcatc aactcttggg ccaccaagtt gtttattgcc attcaattga
361 tgagaaacaa agactcagaa agaaagtagg gagtctctta ctgagtggga ctcacgaggt
421 tctgctttct catctgtcag ttcgcccaac tgtgcgcaac tagcatgatg gctcacacct
481 gtaatcccag cactctggta ggcaaaggtg ggaagattgc ttgagtccag gagttcaaga
541 ctgggctggg caacatggtg aaactctgtc tctacaaaaa attacaaaaa tacaaaaatt
601 agccaggcat agtggtgcat gcctatggtc ccagctactt gggagactga ggtcagagga
661 tc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT06 1100 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 6.
ACCESSION M61839
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 6 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1100)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 43..763
/number=6
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 233 a 302 c 305 g 260 t
ORIGIN Chromosome 2.
1 tcattcatta ttatgtccct ttttgtccct tcaatcctgc agcatgtctt gttctctgac
61 tggcagcctg gcccttcagc ctgaccagca gcaggaccac gagaccacgg actcctctcc
121 tgcctctgcc tatcagagag tctgggaagc atttgccaat cagtccaggg cggaaaggga
181 tgccttcctg caggatactt tccctgaagg cttcctctgg ggtgcctcca caggagcctt
241 taacgtggaa ggaggctggg ccgagggtgg gagaggggtg agcatctggg atccacgcag
301 gcccctgaac accactgagg gccaagcgac gctggaggtg gccagcgaca gttaccacaa
361 ggtagcctct gacgtcgccc tgctttgcgg cctccgggct caggtgtaca agttctccat
421 ctcctggtcc cggatcttcc ccatggggca cgggagcagc cccagcctcc caggcgttgc
481 ctactacaac aagctgattg acaggctaca ggatgcgggc atcgagccca tggccacgct
541 gttccactgg gacctgcctc aggccctgca ggatcatggt ggatggcaga atgagagcgt
601 ggtggatgcc ttcctggact atgcggcctt ctgcttctcc acatttgggg accgtgtgaa
661 gctgtgggtg accttccatg agccgtgggt gatgagctac gcaggctatg gcaccggcca
721 gcaccctccc ggcatctctg acccaggagt ggcctctttt aaggtacttc ccaaccctgc
781 agctcctact aattggagga gaaaggacat tggctggaag aaagtcattt tctctgtttt
841 cttccatcag caagccttta ctttttgttc tttctttaaa ggaaatcggg gagggaagga
901 accataaatt gttaattaaa ttgttaatca cctggccagg tgcagtggct catgccagta
961 atctcttcac tgtgggaggc caaggcaggc agatttcttg agtccaggag ttcgagacca
1021 gactgggcaa catggcgaaa tcttgtctct gcaaaaaaaa tacaaaaatt agctgggcat
1081 agtgttgcac gcctgtgatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT07 770 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 7.
ACCESSION M61840
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 7 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 770)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 98..743
/number=7
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 184 a 204 c 183 g 199 t
ORIGIN Chromosome 2.
1 ggtgacattg ttgttgactt gttattggtt cattagtcct gttgttgtca ttgttattat
61 tactaatcac tgtatttcct tcttactttt tcacaaggtg gctcacttgg tcctcaaggc
121 tcatgccaga acttggcacc actacaacag ccatcatcgc ccacagcagc aggggcacgt
181 gggcattgtg ctgaactcag actgggcaga acccctgtct ccagagaggc ctgaggacct
241 gagagcctct gagcgcttct tgcacttcat gctgggctgg tttgcacacc ccgtctttgt
301 ggatggagac tacccagcca ccctgaggac ccagatccaa cagatgaaca gacagtgctc
361 ccatcctgtg gctcaactcc ccgagttcac agaggcagag aagcagctcc tgaaaggctc
421 tgctgatttt ctgggtctgt cgcattacac ctcccgcctc atcagcaacg ccccacaaaa
481 cacctgcatc cctagctatg ataccattgg aggcttctcc caacacgtga accatgtgtg
541 gccccagacc tcatcctctt ggattcgtgt ggtgccctgg gggataagga ggctgttgca
601 gtttgtatcc ctggaataca caagaggaaa agttccaata taccttgccg ggaatggcat
661 gcccataggg gaaagtgaaa atctctttga tgattcctta agagtagact acttcaatca
721 atatatcaat gaggtgctca agggtaagaa caatggatgt gccagtgatt
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT08 1687 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 8.
ACCESSION M61841
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 8 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1687)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 36..1586
/number=8
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 439 a 440 c 421 g 387 t
ORIGIN Chromosome 2.
1 ccataaataa ataaatctaa tttatttctt cacagctatc aaggaagact ctgtggatgt
61 tcgttcctac attgctcgtt ccctcattga tggcttcgaa ggcccttctg gttacagcca
121 gcggtttggc ctgcaccatg tcaacttcag cgacagcagc aagtcaagga ctcccaggaa
181 atctgcctac tttttcacta gcatcataga aaagaacggt ttcctcacca agggggcaaa
241 aagactgcta ccacctaata cagtaaacct cccctccaaa gtcagagcct tcacttttcc
301 atctgaggtg ccctccaagg ctaaagtcgt ttgggaaaag ttctccagcc aacccaagtt
361 cgaaagagat ttgttctacc acgggacgtt tcgggatgac tttctgtggg gcgtgtcctc
421 ttccgcttat cagattgaag gcgcgtggga tgccgatggc aaaggcccca gcatctggga
481 taactttacc cacacaccag ggagcaatgt gaaagacaat gccactggag acatcgcctg
541 tgacagctat caccagctgg atgccgatct gaatatgctc cgagctttga aggtgaaggc
601 ctaccgcttc tctatctcct ggtctcggat tttcccaact gggagaaaca gctctatcaa
661 cagtcatggg gttgattatt acaacaggct gatcaatggc ttggtggcaa gcaacatctt
721 tcccatggtg acattgttcc attgggacct gccccaggcc ctccaggata tcggaggctg
781 ggagaatcct gccttgattg acttgtttga cagctacgca gacttttgtt tccagacctt
841 tggtgataga gtcaagtttt ggatgacttt taatgagccc atgtacctgg catggctagg
901 ttatggctca ggggaatttc ccccaggggt gaaggaccca ggctgggcac catataggat
961 agcccacgcc gtcatcaaag cccatgccag agtctatcac acgtacgatg agaaatacag
1021 gcaggagcag aagggggtca tctcgctgag cctcagtaca cactgggcag agcccaagtc
1081 accaggggtc cccagagatg tggaagccgc tgaccgaatg ctgcagttct ccctgggctg
1141 gtttgctcac cccattttta gaaacggaga ctatcctgac accatgaagt ggaaagtggg
1201 gaacaggagt gaactgcagc acttagccac ctcccgcctg ccaagcttca ctgaggaaga
1261 gaagaggttc atcagggcga cggccgacgt cttctgcctc aacacgtact actccagaat
1321 cgtgcagcac aaaacaccca ggctaaaccc accctcctac gaagacgacc aggagatggc
1381 tgaggaggag gacccttcgt ggccttccac ggcaatgaac agagctgcgc cctgggggac
1441 gcgaaggctg ctgaactgga tcaaggaaga gtatggtgac atccccattt acatcaccga
1501 aaacggagtg gggctgacca atccgaacac ggaggatact gataggatat tttaccacaa
1561 aacctacatc aatgaggctt tgaaaggtgt gtgagggttc agttcccctt aaagaaatct
1621 tccaacattc cctgggtcat atgcctgaaa tgttttgccg ggatgattta tgaaccatca
1681 atagatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT09 417 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 9.
ACCESSION M61842
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 9 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 417)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 71..339
/number=9
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 85 a 105 c 126 g 101 t
ORIGIN Chromosome 2.
1 gtgggttggc tgcatggagg tcctgactcc tggtgtcaag ctctcctctg ctcctttggg
61 atgttcccag cctacaggct cgatggtata gaccttcgag ggtatgtcgc ctggtctctg
121 atggacaact ttgagtggct aaatggctac acggtcaagt ttggactgta ccatgttgat
181 ttcaacaaca cgaacaggcc tcgcacagca agagcctccg ccaggtacta cacagaggtc
241 attaccaaca acggcatgcc actggccagg gaggatgagt ttctgtacgg acggtttcct
301 gagggcttca tctggagtgc agcttctgct gcatatcagg tgaggagttc aggatggtgg
361 gacacagtga ctgcacacct gccctgtgcc aggctctggg ctcagtgctg ggaaggg
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT10 646 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 10.
ACCESSION M61843
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 10 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 646)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 182..472
/number=10
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 156 a 154 c 176 g 160 t
ORIGIN Chromosome 2.
1 gatcctccca tagcgctggg gttgccggcg tgcagaccac acatggacca atgtgcttgt
61 tttaagctaa gcgttatcac aaaagagtaa acgtcctgac ttgagactca cccagtgaaa
121 gaaaggaggc tgtgagtgct tgactgaatg acttaataag accatgtctt gtcatcttga
181 gattgaaggt gcgtggagag cagatggcaa aggactcagc atttgggaca cgttttctca
241 cacaccactg agggttgaga acgatgccat tggagacgtg gcctgtgaca gttatcacaa
301 gattgctgag gatctggtca ccctgcagaa cctgggcgtg tcccactacc gtttttccat
361 ctcctggtct cgcatcctcc ctgatggaac caccaggtac atcaatgaag cgggcctgaa
421 ctactacgtg aggctcatcg atacactgct ggccgccagc atccagcccc aggtatggtg
481 ggtcctggca aggccttggg aaagtccaca tgcaggaaca gcagggctgg gggagcacat
541 ttatcatgta aacaaaatgc tggtttcaaa tttagctttt gttgttattg ttgtttttga
601 gacgtagtct cgctctgtca cccaggctgg agtgcagtgg cggatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT11 446 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 11.
ACCESSION M61844
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 11 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 446)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 19..217
/number=11
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 108 a 110 c 114 g 114 t
ORIGIN Chromosome 2.
1 gatctggctt cttcccaggt gaccatttac cactgggacc taccacagac gctccaagat
61 gtaggaggct gggagaatga gaccatcgtg cagcggttta aggagtatgc agatgtgctc
121 ttccagaggc tgggagacaa ggtgaagttt tggatcacgt tgaatgagcc ctttgtcatt
181 gcttaccagg gctatggcta cggaacagca gctccaggta agtcccagcc ctggctcata
241 ggctctttga atcatggcat tcttagcaca tcaagagttg aaatccagat ggcacaggac
301 gaggcaacca agaaagcccc atggcagaaa ccctgcctct tgctcagggc tgtagaggtt
361 tccctcctgg cattgcattg ttaaacatga atttcacatc tcaattcctc aaggtgggtt
421 catttctttg ctctgtgact ctgatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT12 642 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 12.
ACCESSION M61845
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 12 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 642)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 58..260
/number=12
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 167 a 152 c 160 g 163 t
ORIGIN Chromosome 2.
1 atctcagtca catccattct atccattctc tgttgacatc catgtgtatg tttccaggag
61 tctccaatag gcctggcact gccccctaca ttgttggcca caatctaata aaggctcatg
121 ctgaggcctg gcatctgtac aacgatgtgt accgcgccag tcaaggtggc gtgatttcca
181 tcaccatcag cagtgactgg gctgaaccca gagatccctc taaccaggag gatgtggagg
241 cagccaggag atatgttcag gtctgttttt cctctgggca cttgttctta ctcttgtcca
301 tctttccttc cagcctaatg gaaacagatt gtgaatcaaa gatttagggt gtggtggctc
361 atgtctataa tcccagcact ttggaagtct gaggcaggag gatttcttga ggctaggagt
421 ttgagactag cctgggcaac atagaaagac cttgtctgtg aagaaaaaaa aattattagg
481 gcatggtgac acacacctat agtcccagct gctcaggagg ctaaggtggg agcttgagtc
541 caggaggtca aggttgcagt gagccatgat ttcggcacca ttaaactcca ggtgacagag
601 ggagaccacc cccaaccccc aaaaagaaga attattagga tc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT13 570 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 13.
ACCESSION M61846
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 13 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 570)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 347..456
/number=13
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 126 a 147 c 180 g 117 t
ORIGIN Chromosome 2.
1 ggaggcttgt gggttctccc tctcctctgc aggacccatc caagggcagc caggaagcat
61 ttgttgagca ccagccagtg cccaggtcag ttactgtcac ctcaagctac aactatgaag
121 aggtggccct gtcctcagtg caacagcaac tgagcaagca cagaccagct gggagacctg
181 tggacactga agctgcaaca gcaggagcca cagggaagag agcttaacct gggggtccag
241 gaaaaggagg gaggttgtga ggccaggcac ttctgagcgg ggacgatgct gtctcttgct
301 gtgcccacct gtaacgcctg ggctgtctcc cccaccctac ccgcagttca tgggaggctg
361 gtttgcacat cctattttca agaatggaga ttacagtgag gtgatgaaga cgcggatccg
421 tgacaggagc ttggctgcag gcctcaacaa gtctcggtaa gggcctggtg cccgcagtgg
481 tgagggcatg ggcgtcgggg tcacagaggc atgtctcggg caagttacca tgactgagct
541 tctttgcttg ctgggaagtt acatgtgatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT14 449 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 14.
ACCESSION M61847
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 14 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 449)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 165..299
/number=14
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 95 a 153 c 100 g 101 t
ORIGIN Chromosome 2.
1 ttcctgcacc gcctgaagga cctcttctcc ttccctgcca gtttccccta ctcactgcca
61 agtgcctggg gttcggagag ctcccccgcc ccagccctat gacgttctct tctcaaagca
121 tggctctccc tgaagccctg ccctcaatgg cttcttccac ccaggctgcc agaatttaca
181 gagagtgaga agaggaggat caacggcacc tatgactttt ttgggttcaa tcactacacc
241 actgtcctcg cctacaacct caactatgcc actgccatct cttcttttga tgcagacagg
301 taagtccacc aacagggagc ctggagccat ctctggaaaa ggcagaaagg tccgcttggc
361 tgtgctctct gaggcctgcc cagcctcaaa acagggcctc caacgccgaa tgtgccgggg
421 tttgcaagat gctcgccacc ccacagatc
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT15 362 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 15.
ACCESSION M61848
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 15 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 362)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 73..296
/number=15
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 90 a 90 c 87 g 95 t
ORIGIN Chromosome 2.
1 ttttgtgttt cgtgtaaagg gcctcttgag atttacaaaa caagacctca tctttagttt
61 ttgaacttgt agaggagttg cttccatcgc agatcgctcg tggccagact ctggctcctt
121 ctggctgaag atgacgcctt ttggcttcag gaggatcctg aactggttaa aggaggaata
181 caatgaccct ccaatttatg tcacagagaa tggagtgtcc cagcgggaag aaacagacct
241 caatgacact gcaaggatct actaccttcg gacttacatc aatgaggccc tcaaaggtac
301 gacgggcccg ccttccccag cgtgcacctt tccctgttgg aaacatctgc tatctgcagg
361 ag
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT16 386 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 16.
ACCESSION M61849
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 16 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 386)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 123..350
/number=16
/product="lactase phlorizin hydrolase"
/gene="LCT"
BASE COUNT 87 a 94 c 115 g 90 t
ORIGIN Chromosome 2.
1 aagcttaccg ccatctgtga aggcggtggg gagagcagta ggcagacctg gcttccgaag
61 gcctggcagg aagctgcctt atgagatagg aaacttatgc ctagtcctct gtgtttgagc
121 agctgtgcag gacaaggtgg accttcgagg atacacagtt tggagtgcga tggacaattt
181 tgagtgggcc acaggctttt cagagagatt tggtctgcat tttgtgaact acagtgaccc
241 ttctctgcca aggatcccca aagcatcagc gaagttctac gcctctgtgg tccgatgcaa
301 tggcttccct gaccccgcta cagggcctca cgcttgtctc caccagccag gtgagatgtg
361 gctctgggag ggaataaagc ctaagg
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS HUMLCT17 840 bp ds-DNA PRI 29-MAR-1991
DEFINITION Human lactase phlorizin hydrolase (LCT) gene, exon 17.
ACCESSION M61850
KEYWORDS beta-glucosidase; lactase phlorizin hydrolase.
SEGMENT 17 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 840)
AUTHORS Boll,W., Wagner,P. and Mantei,N.
TITLE Structure of the chromosomal gene and cDNAs coding for
lactase-phlorizin hydrolase in humans with adult-type hypolactasia
and persistence of lactase
JOURNAL Am. J. Hum. Genet. (1991) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS join(M61834:1037..1676,M61835:479..558,M61836:161..244,
M61837:172..274,M61838:147..225,M61839:43..763,
M61840:98..743,M61841:36..1586,M61842:71..339,
M61843:182..472,M61844:19..217,M61845:58..260,
M61846:347..456,M61847:165..299,M61848:73..296,
M61849:123..350,59..279)
/EC_number="3.2.1.23"
/product="lactase phlorizin hydrolase"
/gene="LCT"
/codon_start=1037
BASE COUNT 227 a 203 c 178 g 232 t
ORIGIN Chromosome 2.
1 gatctgagaa ctcaaatcag cgccagagca ccaaccaccc tgtgtcacac tctcctagat
61 gctggaccca ccatcagccc cgtgagacag gaggaggtgc agttcctggg gctaatgctc
121 ggcaccacag aagcacagac agctttgtac gttctctttt ctcttgtgct tcttggagtc
181 tgtggcttgg catttctgtc atacaagtac tgcaagcgct ctaagcaagg gaaaacacaa
241 cgaagccaac aggaattgag cccggtgtct tcattctgat gagttaccac ctcaagttct
301 atgaagcagg cctagtttct tcatctatgt ttaccggcca ccaaacacct tagggtctta
361 gactctgctg atactggact tctccataaa gtcctgctgc accgttagag atgactttaa
421 tcttgaatga tttcgacttg ctgagtaaaa tggaaatatc tccatcttgc tccagtatca
481 gagttcattt gggcatttga gaagcaagta gctcttgcgg aaacgtgtag atactggtct
541 agtgggtctg tgaaccactt aattgaactt aacagggctg ttttaagttt cagagttgtt
601 aagggttgtt aagggagcaa aaaccgtaaa aatccttcct ataagaagaa atcaactcca
661 ttgcatagac tgcaatatca tctcctgccc ttctgcaagc tctccctagc ttcacatctt
721 gttttccaga aaataaaaac agcagactgt cctttctcct atggttgccc ctccttgaga
781 aagtaggttc aagagaagtt atgaaagtca cacaagccat ctggagctcc gattaagctt
//