GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI01 800 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 1.
ACCESSION M59491
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 1 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 800)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 508..757
/number=1
/note="1 of 2 possible transcription initiation start
sites"
/gene="LACI"
exon 521..757
/number=1
/note="2 of 2 possible transcription initiation start
sites"
/gene="LACI"
BASE COUNT 293 a 155 c 137 g 215 t
ORIGIN
1 gaattcaaat aactgggctg agtagccaag ttagcaagta gctaaggtag ggctcaaagc
61 ctgacacctg caatagataa tgcattacat tgtctcacta agagagacct ccaacggtag
121 ccctcagact tttaaaaaaa ataaatacat tgacagtggg tgaaacaaat gaaataactt
181 gaagaagaaa caaactgcaa aaaagtttat taacagtgta ataataaata tgtaattttt
241 taaaccctaa ctctaggggg aaaaaagcat tctttttcaa ctgattacaa aaacaatcct
301 ggaaagtaaa ggaaatagct attcaaaatg atcgtatctg aaatcttggt gtaagctgtt
361 tccttcatct gtttcctcca ctaaaaaaaa gaaagaaaga aagaaaaaag aggtttagac
421 taaatagagt cagagttgca gtgacctaaa caggaagttg ggctattccc aactgccagt
481 gatctctgaa gccgactctg aggctccctc tttgctctaa cagacagcag cgactttagg
541 ctggataata gtcaaattct tacctcgctc tttcactgct agtaagatca gattgcgttt
601 ctttcagtta ctcttcaatc gccagtttct tgatctgctt ctaaaacaac aactagagaa
661 cataaatcct gtcttcaata cctggaagaa aaacaaaata acctcaactc cgttttgaaa
721 aaaaacattc caagaacttt catcagagat tttacttgtg agtacctggc aatatactgt
781 ctagcccata agaaataact
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI02 181 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 2.
ACCESSION M59492
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 2 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 181)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..151
/number=2
/gene="LACI"
BASE COUNT 53 a 44 c 41 g 43 t
ORIGIN
1 atatctttct ttctctccat gtgcacacag gacaggaaag gccatgtgag gacataggga
61 gaaagcagcc accattgcaa gccaagagag agccctcacc aggaacgatt ggaccagcac
121 cttgatcttg gattttctag cctccagaac tgtgagatac aaatttctgt tgtttaagcc
181 a
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI03 183 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 3.
ACCESSION M59493
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 3 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 183)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..153
/number=3
/gene="LACI"
BASE COUNT 56 a 32 c 34 g 61 t
ORIGIN
1 tattagatat gtatgggttc tgtatttcag agatgattta cacaatgaag aaagtacatg
61 cactttgggc ttctgtatgc ctgctgctta atcttgcccc tgcccctctt aatgctgatt
121 ctgaggaaga tgaagaacac acaattatca caggtaaaat attagaagca attatctttt
181 taa
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI04 258 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 4.
ACCESSION M59494
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 4 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 258)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..228
/number=4
/gene="LACI"
BASE COUNT 82 a 38 c 55 g 83 t
ORIGIN
1 catgttatat cttttatttt tactttatag atacggagtt gccaccactg aaacttatgc
61 attcattttg tgcattcaag gcggatgatg gcccatgtaa agcaatcatg aaaagatttt
121 tcttcaatat tttcactcga cagtgcgaag aatttatata tgggggatgt gaaggaaatc
181 agaatcgatt tgaaagtctg gaagagtgca aaaaaatgtg tacaagaggt aggtttctgg
241 gaacccttat tactcaag
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI05 99 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 5.
ACCESSION M59495
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 5 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 99)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..69
/number=5
/gene="LACI"
BASE COUNT 38 a 11 c 16 g 34 t
ORIGIN
1 attgatatgc atatattctt ttgattacag ataatgcaaa caggattata aagacaacat
61 tgcaacaagg tgaacattta tttgtctgta aatttgaag
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI06 237 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 6.
ACCESSION M59496
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 6 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 237)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..207
/number=6
/gene="LACI"
BASE COUNT 73 a 31 c 48 g 85 t
ORIGIN
1 attgctttct gacattttta taatttctag aaaagccaga tttctgcttt ttggaagaag
61 atcctggaat atgtcgaggt tatattacca ggtattttta taacaatcag acaaaacagt
121 gtgaacgttt caagtatggt ggatgcctgg gcaatatgaa caattttgag acactggaag
181 aatgcaagaa catttgtgaa gatggtcgta agtttatttc ttatttcatt ttagttc
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI07 153 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 7.
ACCESSION M59497
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 7 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 153)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..123
/number=7
/gene="LACI"
BASE COUNT 36 a 33 c 29 g 55 t
ORIGIN
1 tctattttaa ttggctgtat ttttttccag cgaatggttt ccaggtggat aattatggaa
61 cccagctcaa tgctgtgaat aactccctga ctccgcaatc aaccaaggtt cccagccttt
121 ttggtaagaa tcttgtggat tttattgctt cca
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI08 240 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 8.
ACCESSION M59498
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 8 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 240)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 31..210
/number=8
/gene="LACI"
BASE COUNT 72 a 46 c 52 g 70 t
ORIGIN
1 ggcttaccat gttttcctga ttgtttttag aatttcacgg tccctcatgg tgtctcactc
61 cagcagacag aggattgtgt cgtgccaatg agaacagatt ctactacaat tcagtcattg
121 ggaaatgccg cccatttaag tacagtggat gtgggggaaa tgaaaacaat tttacttcca
181 aacaagaatg tctgagggca tgtaaaaaag gtatagaaga tactcttccc attaattgac
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMLPACI09 2849 bp ds-DNA PRI 03-APR-1991
DEFINITION Human lipoprotein-associated coagulation inhibitor (LACI) gene,
exon 9 and complete cds.
ACCESSION M59499
KEYWORDS Kunitz-type inhibitor; extrinsic pathway inhibitor;
factor VIIa inhibitor; factor Xa inhibitor;
lipoprotein-associated coagulation inhibitor; proteinase inhibitor;
tissue factor inhibitor.
SEGMENT 9 of 9
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2849)
AUTHORS Girard,T.J., Eddy,R., Wesselschmidt,R.L., MacPhail,L.A.,
Likert,K.M., Byers,M.G., Shows,T.B. and Broze,G.J.Jr..
TITLE Structure of the human LACI gene: Intron/exon organization and
localization of the gene to chromosome 2
JOURNAL J. Biol. Chem. 266, 5036-5041 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(M59491:508..757,M59492:31..151,M59493:31..153,
M59494:31..228,M59495:31..69,M59496:31..207,
M59497:31..123,M59498:31..210,31..2819)
/note="1 of 2 possible mRNA's"
/gene="LACI"
mRNA join(M59491:521..757,M59492:31..151,M59493:31..153,
M59494:31..228,M59495:31..69,M59496:31..207,
M59497:31..123,M59498:31..210,31..2819)
/note="2 of 2 possible mRNA's"
/gene="LACI"
CDS join(M59493:33..153,M59494:31..228,M59495:31..69,
M59496:31..207,M59497:31..123,M59498:31..210,31..137)
/product="lipoprotein-associated coagulation inhibitor"
/gene="LACI"
/codon_start=33
exon 31..2819
/number=9
/gene="LACI"
BASE COUNT 860 a 527 c 413 g 1049 t
ORIGIN
1 cacattaatt tattcctctt cctcttatag gtttcatcca aagaatatca aaaggaggcc
61 taattaaaac caaaagaaaa agaaagaagc agagagtgaa aatagcatat gaagaaattt
121 ttgttaaaaa tatgtgaatt tgttatagca atgtaacatt aattctacta aatattttat
181 atgaaatgtt tcactatgat tttctatttt tcttctaaaa tgcttttaat taatatgttc
241 attaaatttt ctatgcttat tgtacttgtt atcaacacgt ttgtatcaga gttgcttttc
301 taatcttgtt aaattgctta ttctaggtct gtaatttatt aactggctac tgggaaatta
361 cttattttct ggatctatct gtattttcat ttaactacaa attatcatac taccggctac
421 atcaaatcag tcctttgatt ccatttggtg accatctgtt tgagaatatg atcatgtaaa
481 tgattatctc ctttatagcc tgtaaccaga ttaaggaata cagctcttaa aaaatcaaga
541 acttcctgag tttcacatat aaaatggtga caaacacctg cttctgataa agtttatcca
601 attttgtatt tatagaattc tattatgtgc ttccctcctt agacatagtt tttctccttt
661 tgtactaacc agtacttcca tctatattga gctaaactgt ctttgaacag tcaactctgc
721 atcatgtgcc tgcctgattt ggattggttt cacttttttt ttgtttgacc atagcccatt
781 ctatcagtca agatgactga ataattgtgt gttaaataca actcatgata aggagaacct
841 ttatggaaac aagaagtttt atggaaatcg agagagaatt atttatatgt acttcttaat
901 actatgcttc ccaatatttt ttcttactaa aaataacaaa aatatttaaa ccttctgaaa
961 tctattcagt tatcattagg atttgcacac aatgcaacta ataattcatg ctttaaaaag
1021 taggttattt ctgttgaaga gaaaattatc agcagggaag agtctactag aaaattcatg
1081 tgctagtcat tcttggggat ttaatatttt gctggagtta attcactata tccagacctg
1141 tatctttcat ttattgctga gccatgtgca gtctggcatc tcaacaacct caacaacctc
1201 aacaacctcc aagacatgtc agtttctgta gtgttcacct caaatctgac actggaattg
1261 gaactgattt agaaacaacc atttcattca tttggtatga ctagcttcat gactagcttc
1321 atgaatagct tcatgaatag cttcatgact tctcgctaac aatgatagta taattctgcc
1381 tgttcttcag gattgaaatt ttgaactcaa tttagatttc ctgttttccc tcatatacca
1441 catctaaaca gtctccaaat ctttatgctt tttttttttt tttcaaaaag ttcacccaat
1501 ccctaggctt tttacttttt tctttttctt ttcttttttc ttgttttttt ttttttcatt
1561 ttgttttgtt ttgttatgtt tttttagaca gggtcccact ctgtcaccca ggctggagtg
1621 cagtggtgca atcacaggtc actgaaacct cccacctagc tgggactaga ggtgcaggcc
1681 accacaccag ctaatttatg taatttttgt agagacgagt ttcaccacgt tacctaggct
1741 tgtcttgaac acctgggctc aagcaatctt ccagccccag cctcccaaag tgctgggatt
1801 acaggtataa accacaatgc ccccgttttt actctttact gcatccttcc catcagtatt
1861 aattcctcag aaatttagta cattcctcca ccatttcaaa atgctcccag aactcacact
1921 agttggtact taactacaac cttcaacctc accatttaat tttgatgtat gtttttggat
1981 ttaccaacag tactttcttt catgactact ttgatttagt taagaatgct cactgtacac
2041 tgaatgttaa ttactcagct aattcacact gatttcctgt ttaaaaatat gatcccctcc
2101 aggccattca tgtgaagtca gggtacactg atgccagcta cagaatcact atgtttcaat
2161 atggaatatg aaaagtccta acacataatt gcaaatcatt ttctactatg gtatacaaat
2221 tttatcatta caaaatagta tcagcttttt tcacttaagg aaaataatac atcttcattc
2281 aaatattcag tgcataaata attgccttaa attgagtctt tgctgtggaa tttgagagtt
2341 ttggaaatca aaggcccttg tgaaacattt cctgttgcca tttatttata gatagcaata
2401 gcttcaaatg agtgggaaag tctacttagg tgaagtggta aatagtcact aagattgtat
2461 aaatagcgca ttgatgagtt gcctaattgt tttctccaac aataaccact ggtccattgg
2521 ttcactactt actcaagaaa gacatatact gagattgctt gaaatgttta atgcatgtga
2581 acgttatttt taccgtgttt tggaaaaaga tcttgatgtt attgtcttcc tttattttcc
2641 acaattaagt gcatctaact gtgaattgta tatggaatta cattattcag catatacact
2701 atatttacct gctttgttca ttctctgtat tcaaaattaa cagatcatgc tgaaaaccac
2761 tcaaacgatt atatttttta cattataaga agtaaaatat attattctga ataatgaaac
2821 ctggctgttg tactcgtaaa gattttagt
//