GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMTHRR 3480 bp ds-DNA PRI 03-APR-1991
DEFINITION Human thrombin receptor gene, complete cds.
ACCESSION M62424
KEYWORDS thrombin receptor.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3480)
AUTHORS Vu,T.H., Hung,D.T., Wheaton,V.I. and Coughlin,S.R.
TITLE Molecular cloning of a functional thrombin receptor reveals a novel
proteolytic mechanism of receptor activation
JOURNAL Cell 64, 1057-1068 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 225..1502
/product="thrombin receptor"
/codon_start=225
BASE COUNT 941 a 817 c 785 g 937 t
ORIGIN
1 gcgcccgcgc gaccgcgcgc cccagtcccg ccccgccccg ctaaccgccc cagacacagc
61 gctcgccgag ggtcgcttgg accctgatct tacccgtggg caccctgcgc tctgcctgcc
121 gcgaagaccg gctccccgac ccgcagaagt caggagagag ggtgaagcgg agcagcccga
181 ggcggggcag cctcccggag cagcgccgcg cagagcccgg gacaatgggg ccgcggcggc
241 tgctgctggt ggccgcctgc ttcagtctgt gcggcccgct gttgtctgcc cgcacccggg
301 cccgcaggcc agaatcaaaa gcaacaaatg ccaccttaga tccccggtca tttcttctca
361 ggaaccccaa tgataaatat gaaccatttt gggaggatga ggagaaaaat gaaagtgggt
421 taactgaata cagattagtc tccatcaata aaagcagtcc tcttcaaaaa caacttcctg
481 cattcatctc agaagatgcc tccggatatt tgaccagctc ctggctgaca ctctttgtcc
541 catctgtgta caccggagtg tttgtagtca gcctcccact aaacatcatg gccatcgttg
601 tgttcatcct gaaaatgaag gtcaagaagc cggcggtggt gtacatgctg cacctggcca
661 cggcagatgt gctgtttgtg tctgtgctcc cctttaagat cagctattac ttttccggca
721 gtgattggca gtttgggtct gaattgtgtc gcttcgtcac tgcagcattt tactgtaaca
781 tgtacgcctc tatcttgctc atgacagtca taagcattga ccggtttctg gctgtggtgt
841 atcccatgca gtccctctcc tggcgtactc tgggaagggc ttccttcact tgtctggcca
901 tctgggcttt ggccatcgca ggggtagtgc ctctcgtcct caaggagcaa accatccagg
961 tgcccgggct caacatcact acctgtcatg atgtgctcaa tgaaaccctg ctcgaaggct
1021 actatgccta ctacttctca gccttctctg ctgtcttctt ttttgtgccg ctgatcattt
1081 ccacggtctg ttatgtgtct atcattcgat gtcttagctc ttccgcagtt gccaaccgca
1141 gcaagaagtc ccgggctttg ttcctgtcag ctgctgtttt ctgcatcttc atcatttgct
1201 tcggacccac aaacgtcctc ctgattgcgc attactcatt cctttctcac acttccacca
1261 cagaggctgc ctactttgcc tacctcctct gtgtctgtgt cagcagcata agctcgtgca
1321 tcgaccccct aatttactat tacgcttcct ctgagtgcca gaggtacgtc tacagtatct
1381 tatgctgcaa agaaagttcc gatcccagca gttataacag cagtgggcag ttgatggcaa
1441 gtaaaatgga tacctgctct agtaacctga ataacagcat atacaaaaag ctgttaactt
1501 aggaaaaggg actgctggga ggttaaaaag aaaagtttat aaaagtgaat aacctgagga
1561 ttctattagt ccccacccaa actttattga ttcacctcct aaaacaacag atgtacgact
1621 tgcatacctg ctttttatgg gagctgtcaa gcatgtattt ttgtcaatta ccagaaagat
1681 aacaggacga gatgacggtg ttattccaag ggaatattgc caatgctaca gtaataaatg
1741 aatgtcactt ctggatatag ctaggtgaca tatacatact tacatgtgtg tatatgtaga
1801 tgtatgcaca cacatatatt atttgcagtg cagtatagaa taggcacttt aaaacactct
1861 ttccccgcac cccagcaatt atgaaaataa tctctgattc cctgatttaa tatgcaaagt
1921 ctaggttggt agagtttagc cctgaacatt tcatggtgtt catcaacagt gagagactcc
1981 atagtttggg cttgtaccac ttttgcaaat aagtgtattt tgaaattgtt tgacggcaag
2041 gtttaagtta ttaagaggta agacttagta ctatctgtgc gtagaagttc tagtgttttc
2101 aattttaaac atatccaagt ttgaattcct aaaattatgg aaacagatga aaagcctctg
2161 ttttgatatg ggtagtattt tttacatttt acacactgta cacataagcc aaaactgagc
2221 ataagtcctc tagtgaatgt aggctggctt tcagagtagg ctattcctga gagctgcatg
2281 tgtccgcccc cgatggagga ctccaggcag cagacacatg ccagggccat gtcagacaca
2341 gattggccag aaaccttcct gctgagcctc acagcagtga gactggggcc actacatttg
2401 ctccatcctc ctgggattgg ctgtgaactg atcatgttta tgagaaactg gcaaagcaga
2461 atgtgatatc ctaggaggta atgaccatga aagacttctc tacccatctt aaaaacaacg
2521 aaagaaggca tggacttctg gatgcccatc cactgggtgt aaacacatct agtagttgtt
2581 ctgaaatgtc agttctgata tggaagcacc cattatgcgc tgtggccact ccaataggtg
2641 ctgagtgtac agagtggaat aagacagaga cctgccctca agagcaaagt agatcatgca
2701 tagagtgtga tgtatgtgta ataaatatgt ttcacacaaa caaggcctgt cagctaaaga
2761 agtttgaaca tttgggttac tatttcttgt ggttataact taatgaaaac aatgcagtac
2821 aggacatata ttttttaaaa taagtctgat ttaattgggc actatttatt tacaaatgtt
2881 ttgctcaata gattgctcaa atcaggtttt cttttaagaa tcaatcatgt cagtctgctt
2941 agaaataaca gaagaaaata gaattgacat tgaaatctag gaaaattatt ctataatttc
3001 catttactta agacttaatg agactttaaa agcatttttt aacctcctaa gtatcaagta
3061 tagaaaatct tcatggaatt cacaaagtaa tttggaaatt aggttgaaac atatctctta
3121 tcttacgaaa aaatggtagc attttaaaca aaatagaaag ttgcaaggca aatgtttatt
3181 taaaagagca ggccaggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggctga
3241 ggcgggtgga tcacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaacccgt
3301 ctctactaaa aatgcaaaaa aaattagccg ggcgtggtgg caggcacctg tagtcccagc
3361 tactcgggag gctgaggcag gagactggcg tgaacccagg aggcggacct tgtagtgagc
3421 cgagatcgcg ccactgtgct ccagcctggg caacagagca agactccatc tcaaaaaaaa
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