GenBank-Updates@genbank.bio.net (03/23/91)
LOCUS HUMMHDRDW4 221 bp ds-DNA PRI 23-MAR-1991
DEFINITION Human MHC class II HLA-DRB1 gene from HLA-DR4/Dw14.
ACCESSION M63338
KEYWORDS cell surface glycoprotein; class II gene;
integral membrane protein; major histocompatibility complex.
SOURCE Human (individual isolate KH002 with mixed connective tissue
disease, HLA-DR3,4;DQw 2,3 haplotype) white blood cell PCR
amplified DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS Kaneoka,H., Lee,D.R., Hsu,K.-C., Sharp,G.C. and Hoffman,R.W.
TITLE Solid-phase direct DNA sequencing of allele-specific polymerase
chain reaction-amplified HLA-DR genes
JOURNAL BioFeedback 10, 30-35 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 1..221
/product="MHC class II HLA-DR4/Dw14"
/gene="MHC class II HLA-DRB1"
/codon_start=3
/partial
misc_feature 181..181
/note="site of polymorphism"
BASE COUNT 47 a 54 c 83 g 37 t
ORIGIN chromosome 6p21.3
1 agtgtcattt cttcaacggg acggagcggg tgcggttcct ggacagatac ttctatcacc
61 aagaggagta cgtgcgcttc gacagcgacg tgggggagta ccgggcggtg acggagctgg
121 ggcggcctga tgccgagtac tggaacagcc agaaggacct cctggagcag aggcgggccg
181 cggtggacac ctactgcaga cacaactacg gggttggtga g
//GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMMHDRDW4 221 bp ds-DNA PRI 03-APR-1991
DEFINITION Human MHC class II HLA-DRB1 gene from HLA-DR4/Dw14.
ACCESSION M63338
KEYWORDS cell surface glycoprotein; class II gene;
integral membrane protein; major histocompatibility complex.
SOURCE Human (individual isolate KH002 with mixed connective tissue
disease, HLA-DR3,4;DQw 2,3 haplotype) white blood cell PCR
amplified DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS Kaneoka,H., Lee,D.R., Hsu,K.-C., Sharp,G.C. and Hoffman,R.W.
TITLE Solid-phase direct DNA sequencing of allele-specific polymerase
chain reaction-amplified HLA-DR genes
JOURNAL BioTechniques 10, 30-35 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 1..221
/product="MHC class II HLA-DR4/Dw14"
/gene="MHC class II HLA-DRB1"
/codon_start=3
/partial
misc_feature 181..181
/note="site of polymorphism"
BASE COUNT 47 a 54 c 83 g 37 t
ORIGIN chromosome 6p21.3
1 agtgtcattt cttcaacggg acggagcggg tgcggttcct ggacagatac ttctatcacc
61 aagaggagta cgtgcgcttc gacagcgacg tgggggagta ccgggcggtg acggagctgg
121 ggcggcctga tgccgagtac tggaacagcc agaaggacct cctggagcag aggcgggccg
181 cggtggacac ctactgcaga cacaactacg gggttggtga g
//