GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMFOSB 4145 bp ss-mRNA PRI 14-MAR-1991
DEFINITION Human fosB mRNA, complete cds.
ACCESSION X14897
KEYWORDS c-myc oncogene; fos cellular oncogene; fosB oncogene;
transcription factor; transcription factor AP-1.
SOURCE Human, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4145)
AUTHORS Zerial,M., Toschi,L., Ryseck,R.P., Schuermann,M., Mueller,R. and
Bravo,R.
TITLE The product of a novel growth factor activated gene, FosB,
interacts with JUN proteins enhancing their DNA binding activity
JOURNAL EMBO J. 8, 805-813 (1989)
STANDARD simple staff_review
REFERENCE 2 (bases 1 to 4145)
AUTHORS Nakabeppu,Y. and Nathans,D.
TITLE A naturally occurring truncated form of FosB that inhibits Fos/Jun
transcriptional activity
JOURNAL Cell 64, 751-759 (1991)
STANDARD simple staff_review
COMMENT clone=AC113-1; cell line=NIH3T3;
FEATURES Location/Qualifiers
mRNA join(<1..1912,2053..>4145)
/note="delta-FosB transcript"
/gene="fosB"
mRNA <1..>4145
/gene="fosB"
CDS join(1202..1912,2053..2055)
/note="delta-FosB"
/gene="fosB"
/codon_start=1202
CDS 1202..2218
/gene="fosB"
/codon_start=1202
BASE COUNT 960 a 1186 c 1007 g 991 t 1 others
ORIGIN
1 ataaattctt attttgacac tcaccaaaat agtcacctgg aaaacccgct ttttgtgaca
61 aagtacagaa ggcttggtca catttaaatc actgagaact agagagaaat actatcgcaa
121 actgtaatag acattacatc cataaaagtt tccccagtcc ttattgtaat attgcacagt
181 gcaattgcta catggcaaac tagtgtagca tagaagtcaa agcaaaaaca aaccaaagaa
241 aggagccaca agagtaaaac tgttcaacag ttaatagttc aaactaagcc attgaatcta
301 tcattgggat cgttaaaatg aatcttccta caccttgcag tgtatgattt aacttttaca
361 gaacacaagc caagtttaaa atcagcagta gagatattaa aatgaaaagg tttgctaata
421 gagtaacatt aaataccctg aaggaaaaaa aacctaaata tcaaaataac tgattaaaat
481 tcacttgcaa attagcacac gaatatgcaa cttggaaatc atgcagtgtt ttatttaaga
541 aaacataaaa caaaactatt aaaatagttt tagagggggt aaaatccagg tcctctgcca
601 ggatgctaaa attagacttc aggggaattt tgaagtcttc aattttgaaa cctattaaaa
661 agcccatgat tacagttaat taagagcagt gcacgcaaca gtgacacgcc tttagagagc
721 attactgtgt atgaacatgt tggctgctac cagccacagt caatttaaca aggctgctca
781 gtcatgaact taatacagag agagcacgcc taggcagcaa gcacagcttg ctgggccact
841 ttcctccctg tcgtgacaca atcaatccgt gtacttggtg tatctgaagc gcacgctgca
901 ccgcggcact gcccggcggg tttctgggcg gggagcgatc cccgcgtcgc cccccgtgaa
961 accgacagag cctggacttt caggaggtac agcggcggtc tgaaggggat ctgggatctt
1021 gcagagggaa cttgcatcga aacttgggca gttctccgaa ccggagacta agcttccccg
1081 agcagcgcac tttggagacg tgtccggtct actccggact cgcatctcat tccactcggc
1141 catagccttg gcttcccggc gacctcagcg tggtcacagg ggcccccctg tgcccaggga
1201 aatgtttcaa gcttttcccg gagactacga ctccggctcc cggtgtagct catcaccctc
1261 cgccgagtct cagtacctgt cttcggtgga ctccttcggc agtccaccca ccgccgccgc
1321 ctcccaggag tgcgccggtc tcggggaaat gcccggctcc ttcgtgccaa cggtcaccgc
1381 aatcacaacc agccaggatc ttcagtggct cgtgcaaccc accctcatct cttccatggc
1441 ccagtcccag gggcagccac tggcctccca gcctccagct gttgaccctt atgacatgcc
1501 aggaaccagc tactcaaccc caggcctgag tgcctacagc actggcgggg caagcggaag
1561 tggtgggcct tcaaccagca caaccaccag tggacctgtg tctgcccgtc cagccagagc
1621 caggcctaga agaccccgag aagagacact taccccagaa gaagaagaaa agcgaagggt
1681 tcgcagagag cggaacaagc tggctgcagc taagtgcagg aaccgtcgga gggagctgac
1741 agatcgactt caggcggaaa ctgatcagct tgaagaggaa aaggcagagc tggagtcgga
1801 gatcgccgag ctgcaaaaag agaaggaacg cctggagttt gtcctggtgg cccacaaacc
1861 gggctgcaag atcccctacg aagaggggcc ggggccaggc ccgctggccg aggtgagaga
1921 tttgccaggg tcaacatccg ctaaggaaga cggcttcggc tggctgctgc cgccccctcc
1981 accacccccc ctgcccttcc agagcagccg agacgcaccc cccaacctga cggcttctct
2041 ctttacacac agtgaagttc aagtcctcgg cgaccccttc cccgttgtta gcccttcgta
2101 cacttcctcg tttgtcctca cctgcccgga ggtctccgcg ttcgccggcg cccaacgcac
2161 cagcggcagc gagcagccgt ccgacccgct gaactcgccc tcccttcttg ctctgtaaac
2221 tctttagaca aacaaaacaa acaaacccgc aaggaacaag gaggaggaag atgaggagga
2281 gaggggagga agcagtccgg gggtgtgtgt gtggaccctt tgactcttct gtctgaccac
2341 ctgccgcctc tgccatcgga catgacggaa ggacctcctt tgtgttttgt gctccgtctc
2401 tggttttctg tgccccggcg agaccggaga gctggtgact ttggggacag ggggtggggc
2461 ggggatggac acccctcctg catatctttg tcctgttact tcaacccaac ttctggggat
2521 agatggctgg ctgggtgggt agggtggggt gcaacgccca cctttggcgt cttgcgtgag
2581 gctggagggg aaagggtgct gagtgtgggg tgcagggtgg gttgaggtcg agctggcatg
2641 cacctccaga gagacccaac gaggaaatga cagcaccgtc ctgtccttct tttcccccac
2701 ccacccatcc accctcaagg gtgcagggtg accaagatag ctctgttttg ctccctcggg
2761 ccttagctga ttaacttaac atttccaaga ggttacaacc tcctcctgga cgaattgagc
2821 ccccgactga gggaagtcga tgcccccttt gggagtctgc taaccccact tcccgctgat
2881 tccaaaatgt gaacccctat ctgactgctc agtctttccc tcctgggaaa actggctcag
2941 gttggatttt tttcctcgtc tgctacagag ccccctccca actcaggccc gctcccaccc
3001 ctgtgcagta ttatgctatg tccctctcac cctcaccccc accccaggcg cccttggccg
3061 tcctcgttgg gccttactgg ttttgggcag cagggggcgc tgcgacgccc atcttgctgg
3121 agcgctttat actgtgaatg agtggtcgga ttgctgggtg cgccggatgg gattgacccc
3181 cagccctcca aaactttccc tgggcctccc cttcttccac ttgcttcctc cctccccttg
3241 acagggagtt agactcgaaa ggatgaccac gacgcatccc ggtggccttc ttgctcaggc
3301 cccagacttt ttctctttaa gtccttcgcc ttccccagcc taggacgcca acttctcccc
3361 accctgggag ccccgcatcc tctcacagag gtcgaggcaa ttttcagaga agttttcagg
3421 gctgaggctt tggctcccct atcctcgata tttgaatccc caaatatttt tggactagca
3481 tacttaagag ggggctgagt tcccactatc ccactccatc caattccttc agtcccaaag
3541 acgagttctg tcccttccct ccagctttca cctcgtgaga atcccacgag tcagatttct
3601 attttttaat attggggaga tgggccctac cgcccgtccc ccgtgctgca tggaacattc
3661 cataccctgt cctgggccct aggttccaaa cctaatccca aaccccaccc ccagctattt
3721 atccctttcc tggttcccaa aaagcactta tatctattat gtataaataa atatattata
3781 tatgagtgtg cgtgtgtgtg cgtgtgcgtg cgtgcgtgcg tgcgtgcgag cttccttgtt
3841 ttcaagtgtg ctgtggagtt caaaatcgct tctggggatt tgagtcagac tttctggctg
3901 tccctttttg tcaccttttt gttgttgtct cggctcctct ggctgttgga gacagtcccg
3961 gcctctccct ttatcctttc tcaagtctgt ctcgctcaga ccacttccaa catgtctcca
4021 ctctcaatga ctctgatctc cggtntgtct gttaattctg gatttgtcgg ggacatgcaa
4081 ttttacttct gtaagtaagt gtgactgggt ggtagatttt ttacaatcta tatcgttgag
4141 aattc
//GenBank-Updates@genbank.bio.net (04/04/91)
LOCUS HUMFOSB 4145 bp ss-mRNA PRI 04-APR-1991
DEFINITION Human fosB mRNA, complete cds.
ACCESSION X14897
KEYWORDS c-myc oncogene; fos cellular oncogene; fosB oncogene;
transcription factor; transcription factor AP-1.
SOURCE Human, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4145)
AUTHORS Zerial,M., Toschi,L., Ryseck,R.-P., Schuermann,M., Mueller,R. and
Bravo,R.
TITLE The product of a novel growth factor activated gene, fos B,
interacts with JUN proteins enhancing their DNA binding activity
JOURNAL EMBO J. 8, 805-813 (1989)
STANDARD simple staff_review
REFERENCE 2 (bases 1 to 4145)
AUTHORS Nakabeppu,Y. and Nathans,D.
TITLE A naturally occurring truncated form of FosB that inhibits Fos/Jun
transcriptional activity
JOURNAL Cell 64, 751-759 (1991)
STANDARD full staff_review
COMMENT clones=AC113-[1-3]; cell line=NIH3T3 [EMBO J. 8, 805-813 (1989)].
FEATURES Location/Qualifiers
mRNA join(<1..1912,2053..>4145)
/note="delta-FosB transcript"
/gene="fosB"
/citation=Cell 64, 751-759 (1991)
mRNA <1..>4145
/gene="fosB"
CDS join(1202..1912,2053..2055)
/note="delta-FosB"
/gene="fosB"
/codon_start=1202
/citation=Cell 64, 751-759 (1991)
CDS 1202..2218
/gene="fosB"
/codon_start=1202
BASE COUNT 960 a 1186 c 1007 g 991 t 1 others
ORIGIN
1 ataaattctt attttgacac tcaccaaaat agtcacctgg aaaacccgct ttttgtgaca
61 aagtacagaa ggcttggtca catttaaatc actgagaact agagagaaat actatcgcaa
121 actgtaatag acattacatc cataaaagtt tccccagtcc ttattgtaat attgcacagt
181 gcaattgcta catggcaaac tagtgtagca tagaagtcaa agcaaaaaca aaccaaagaa
241 aggagccaca agagtaaaac tgttcaacag ttaatagttc aaactaagcc attgaatcta
301 tcattgggat cgttaaaatg aatcttccta caccttgcag tgtatgattt aacttttaca
361 gaacacaagc caagtttaaa atcagcagta gagatattaa aatgaaaagg tttgctaata
421 gagtaacatt aaataccctg aaggaaaaaa aacctaaata tcaaaataac tgattaaaat
481 tcacttgcaa attagcacac gaatatgcaa cttggaaatc atgcagtgtt ttatttaaga
541 aaacataaaa caaaactatt aaaatagttt tagagggggt aaaatccagg tcctctgcca
601 ggatgctaaa attagacttc aggggaattt tgaagtcttc aattttgaaa cctattaaaa
661 agcccatgat tacagttaat taagagcagt gcacgcaaca gtgacacgcc tttagagagc
721 attactgtgt atgaacatgt tggctgctac cagccacagt caatttaaca aggctgctca
781 gtcatgaact taatacagag agagcacgcc taggcagcaa gcacagcttg ctgggccact
841 ttcctccctg tcgtgacaca atcaatccgt gtacttggtg tatctgaagc gcacgctgca
901 ccgcggcact gcccggcggg tttctgggcg gggagcgatc cccgcgtcgc cccccgtgaa
961 accgacagag cctggacttt caggaggtac agcggcggtc tgaaggggat ctgggatctt
1021 gcagagggaa cttgcatcga aacttgggca gttctccgaa ccggagacta agcttccccg
1081 agcagcgcac tttggagacg tgtccggtct actccggact cgcatctcat tccactcggc
1141 catagccttg gcttcccggc gacctcagcg tggtcacagg ggcccccctg tgcccaggga
1201 aatgtttcaa gcttttcccg gagactacga ctccggctcc cggtgtagct catcaccctc
1261 cgccgagtct cagtacctgt cttcggtgga ctccttcggc agtccaccca ccgccgccgc
1321 ctcccaggag tgcgccggtc tcggggaaat gcccggctcc ttcgtgccaa cggtcaccgc
1381 aatcacaacc agccaggatc ttcagtggct cgtgcaaccc accctcatct cttccatggc
1441 ccagtcccag gggcagccac tggcctccca gcctccagct gttgaccctt atgacatgcc
1501 aggaaccagc tactcaaccc caggcctgag tgcctacagc actggcgggg caagcggaag
1561 tggtgggcct tcaaccagca caaccaccag tggacctgtg tctgcccgtc cagccagagc
1621 caggcctaga agaccccgag aagagacact taccccagaa gaagaagaaa agcgaagggt
1681 tcgcagagag cggaacaagc tggctgcagc taagtgcagg aaccgtcgga gggagctgac
1741 agatcgactt caggcggaaa ctgatcagct tgaagaggaa aaggcagagc tggagtcgga
1801 gatcgccgag ctgcaaaaag agaaggaacg cctggagttt gtcctggtgg cccacaaacc
1861 gggctgcaag atcccctacg aagaggggcc ggggccaggc ccgctggccg aggtgagaga
1921 tttgccaggg tcaacatccg ctaaggaaga cggcttcggc tggctgctgc cgccccctcc
1981 accacccccc ctgcccttcc agagcagccg agacgcaccc cccaacctga cggcttctct
2041 ctttacacac agtgaagttc aagtcctcgg cgaccccttc cccgttgtta gcccttcgta
2101 cacttcctcg tttgtcctca cctgcccgga ggtctccgcg ttcgccggcg cccaacgcac
2161 cagcggcagc gagcagccgt ccgacccgct gaactcgccc tcccttcttg ctctgtaaac
2221 tctttagaca aacaaaacaa acaaacccgc aaggaacaag gaggaggaag atgaggagga
2281 gaggggagga agcagtccgg gggtgtgtgt gtggaccctt tgactcttct gtctgaccac
2341 ctgccgcctc tgccatcgga catgacggaa ggacctcctt tgtgttttgt gctccgtctc
2401 tggttttctg tgccccggcg agaccggaga gctggtgact ttggggacag ggggtggggc
2461 ggggatggac acccctcctg catatctttg tcctgttact tcaacccaac ttctggggat
2521 agatggctgg ctgggtgggt agggtggggt gcaacgccca cctttggcgt cttgcgtgag
2581 gctggagggg aaagggtgct gagtgtgggg tgcagggtgg gttgaggtcg agctggcatg
2641 cacctccaga gagacccaac gaggaaatga cagcaccgtc ctgtccttct tttcccccac
2701 ccacccatcc accctcaagg gtgcagggtg accaagatag ctctgttttg ctccctcggg
2761 ccttagctga ttaacttaac atttccaaga ggttacaacc tcctcctgga cgaattgagc
2821 ccccgactga gggaagtcga tgcccccttt gggagtctgc taaccccact tcccgctgat
2881 tccaaaatgt gaacccctat ctgactgctc agtctttccc tcctgggaaa actggctcag
2941 gttggatttt tttcctcgtc tgctacagag ccccctccca actcaggccc gctcccaccc
3001 ctgtgcagta ttatgctatg tccctctcac cctcaccccc accccaggcg cccttggccg
3061 tcctcgttgg gccttactgg ttttgggcag cagggggcgc tgcgacgccc atcttgctgg
3121 agcgctttat actgtgaatg agtggtcgga ttgctgggtg cgccggatgg gattgacccc
3181 cagccctcca aaactttccc tgggcctccc cttcttccac ttgcttcctc cctccccttg
3241 acagggagtt agactcgaaa ggatgaccac gacgcatccc ggtggccttc ttgctcaggc
3301 cccagacttt ttctctttaa gtccttcgcc ttccccagcc taggacgcca acttctcccc
3361 accctgggag ccccgcatcc tctcacagag gtcgaggcaa ttttcagaga agttttcagg
3421 gctgaggctt tggctcccct atcctcgata tttgaatccc caaatatttt tggactagca
3481 tacttaagag ggggctgagt tcccactatc ccactccatc caattccttc agtcccaaag
3541 acgagttctg tcccttccct ccagctttca cctcgtgaga atcccacgag tcagatttct
3601 attttttaat attggggaga tgggccctac cgcccgtccc ccgtgctgca tggaacattc
3661 cataccctgt cctgggccct aggttccaaa cctaatccca aaccccaccc ccagctattt
3721 atccctttcc tggttcccaa aaagcactta tatctattat gtataaataa atatattata
3781 tatgagtgtg cgtgtgtgtg cgtgtgcgtg cgtgcgtgcg tgcgtgcgag cttccttgtt
3841 ttcaagtgtg ctgtggagtt caaaatcgct tctggggatt tgagtcagac tttctggctg
3901 tccctttttg tcaccttttt gttgttgtct cggctcctct ggctgttgga gacagtcccg
3961 gcctctccct ttatcctttc tcaagtctgt ctcgctcaga ccacttccaa catgtctcca
4021 ctctcaatga ctctgatctc cggtntgtct gttaattctg gatttgtcgg ggacatgcaa
4081 ttttacttct gtaagtaagt gtgactgggt ggtagatttt ttacaatcta tatcgttgag
4141 aattc
//