GenBank-Updates@genbank.bio.net (04/04/91)
LOCUS MUSCOL2A1C 1528 bp ds-DNA ROD 04-APR-1991
DEFINITION Mouse alpha-1 type II collagen gene, exons 51 and 52.
ACCESSION M63708
KEYWORDS alpha-1 type II collagen.
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Cheah,K.S.E., Au,P.K.C.., Lau,E.T., Little,P.F.R.. and Stubbs,L.
TITLE The mouse Col2a-1 gene is highly conserved and is linked to Int-1
on chromosome 15
JOURNAL Mammal. Genome (1991) In press
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1528)
AUTHORS Cheah,K.S.E.., Au,P.K.C.., Lau,E.T., Little,P.F.R.. and Stubbs,L.
TITLE The mouse Col2a-1 gene is highly conserved and is linked to Int-1
on chromosome 15
JOURNAL Mammalian Genome (1991) In press
STANDARD full automatic
FEATURES Location/Qualifiers
CDS join(47..289,743..890)
/product="alpha 1 type I collagen"
/gene="Col2a-1"
/codon_start=47
/partial
mRNA join(47..289,743..1095)
/product="alpha 1 type I collagen"
/gene="Col2a-1"
/partial
mRNA join(47..289,743..1298)
/product="alpha 1 type I collagen"
/gene="Col2a-1"
/partial
intron 1..46
/function="intron"
/cons_splice=(5'site: NO, 3'site: YES)
/standard_name="alpha 1 type II collagen"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
/partial
exon 47..289
/number=exon 51
/standard_name="alpha 1 type II collagen"
/note="encoding aa 143-224 of C-propeptide"
/product="type II collagen C-propeptide region"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
intron 290..742
/function="intron"
/standard_name="alpha 1 type II collagen"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
exon 743..1095
/number=exon 52
/standard_name="alpha 1 type II collagen"
/note="includes termination codon and 3' UT"
/product="type II collagen"
/gene="col2a-1"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
exon 743..1298
/number=exon 52
/standard_name="alpha 1 type II collagen"
/note="alternative polyadenylation signal and cleavage"
/product="type II collagen"
/gene="col2a-1"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
misc_signal 887..890
/function="type II collagen"
/phenotype="translation termination codon"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
3'UTR 890..1095
/function="the result of one of 2 polyadenylation sites"
/standard_name="alpha 1 type II collagen gene"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
polyA_signal 1073..1078
/standard_name="alpha 1 type II collagen"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
polyA_signal 1291..1296
/standard_name="alpha 1 type II collagen"
/evidence=EXPERIMENTAL
/citation=Mammal. Genome 1, ??-?? (1991)
BASE COUNT 392 a 398 c 384 g 354 t
ORIGIN
1 gatgctaggc ccctggtctc acaaccctcg cccctctgcc ccacagttca gctatggcga
61 tggcaacctg gctcccaaca ccgctaacgt ccagatgact ttcctccgtc tactgtccac
121 tgagggctcc cagaacatca cctaccactg taagaacagc atcgcctacc tggacgaagc
181 ggctggcaac ctcaagaagg ccttgctcat ccagggctcc aatgatgtag agatgagggc
241 cgagggcaac agcaggttca catacactgc cctgaaggat ggctgcacgg tgagtggggc
301 tgaggtcagc ctgtgacaaa tgtcactttc ctgtagtgaa gggactcatt agaggcttga
361 gtcgtggggg catgtgggag acaagctgag aggcagggat gggggaggag cgtataccat
421 actggcttgt ccacttcctc attcagaggc aataaagatg ctggcaagct cactaactct
481 tatagaagta ttcgtagaaa ctagcatagg agaggagagg ctatcccagg caggaagcct
541 ctgtgggaag gaggaagaca agtagaggag ggctctacca tcaaggggac aattgaagag
601 gagagggctt gggcaaatgg agagaagttc tagcaagcca cccagtgtcg tccctacctt
661 gtggctgctt agtttggggg tgctaagtag ccagtccttg ctgtaaggca tcgccaaatg
721 acacctcccc ttttctgcct agaaacacac tggtaagtgg ggcaagaccg tcatcgagta
781 ccgatcacag aagacctccc gccttcccat tattgacatc gcacccatgg acattggagg
841 ggctgaacag gaatttggtg tggacatagg gcctgtctgc ttcttgtaaa acccccgaac
901 cctgaaacaa cacaatccat tgcgaaccca aaggacccaa acactttcca accgcagtca
961 ctccaggatc tgcactgaat ggctgacctg acctgatgat acccaaccgt cctcccctca
1021 cagcccggac tgtgctcccc tttctaagag acctgaactg ggcagactgc aaaataaaat
1081 ctcggtgttc tatttattta ttgtcttcct gtaagacctc tgggtccagg cggagacagg
1141 aactatctgg tgtgagtcag acgccccccg agtgactgtt cccagcccag ccagaagacc
1201 cctacagatg ctgggcgcag ggactgctgt cctacacaat ggtgctattc tgtgtcaaac
1261 acctctgtat tttttaaaac atcaattgat attaaaaacc aaaaaaaaaa aaatcattgg
1321 aaaggatatg gtgacttgtg ttttgttctt tgttttgttc ttccggttgt atttactagt
1381 ccttggttct ataaggcatg cccaaatatg gtcccaggac tgtctgtgga ccttacaatc
1441 caggatgctg aagtcacact gcctggtttg gtgatgtcac tcacacacac aaaagacctg
1501 cctctcttgt aaacttgggc actttgtg
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