GenBank-Updates@genbank.bio.net (03/27/91)
LOCUS RABIGK1B6 4305 bp ds-DNA MAM 27-MAR-1991
DEFINITION Rabbit IgK 1b6 unrearranged kappa chain J3, 4 and 5 regions (bp
1-3872) and rearranged C region (bp 3873-4305).
ACCESSION M37809 M29583
KEYWORDS constant region; germline; immunoglobulin kappa chain;
immunoglobulin light chain; joining exon; processed gene.
SOURCE Rabbit cell line RMH H158 DNA.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 4305)
AUTHORS Dreher,K.L., Asundi,V., Wolf,B. and Bruggeman,L.
TITLE rabbit ig k1b6 gene structure
JOURNAL J. Immunol. 145, 325-330 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS join(125..160,3702..4016)
/product="immunoglobulin kappa chain"
/gene="IgK"
/codon_start=125
/partial
CDS join(414..449,3702..4016)
/product="immunoglobulin kappa chain"
/gene="IgK"
/codon_start=414
/partial
CDS join(707..743,3702..4016)
/product="immunoglobulin kappa chain"
/gene="IgK"
/codon_start=707
/partial
BASE COUNT 1230 a 908 c 986 g 1180 t 1 others
ORIGIN
1 gatgaggcac agaggaggga aaactgtctg agatttccaa gtgaaaataa gttcctcggg
61 gagagcgttg ccgccttgtc agggagggtt taatggaggg agaaggtaaa gggagccacc
121 gtgatccact cttggcccag ggaccaaact ggaaatcaaa cctaagtccc tttctgtcca
181 actgtgaggt cttggtcccc tggatcacct gggcaagttt gtgatgtttc agttaaatga
241 gccattcctg gcgaccccaa aagtaaatag aagaaaatct tcaaaagcgg agaagacaga
301 aatttggggg tttgggagaa taggagagaa acaacagaag tttctccaca attgccgtgt
361 ggtgggactg gccgcaaagg gaggtttttg tgaggggtgg gatgacagag tgacttgctt
421 ttggctcagg gaccatggtg gagatcagat gtaagtgcac tttcccagtc cttttccgta
481 ctaagttggt aaatgtggga tttgcgcatt tgggagatga gttaaggtcg atccggaggg
541 gaatggaatt tttccaaaaa cacggatggg tagggagcag aatatctgtt catctcaaat
601 agagagcaaa gagctagcga gtggccaaat tctgtctgtc agtctaatga gcttgggagc
661 agtcagaggt ttttgttgag ggaaagcaat aaagctaatt ccatgaatca cctttggcga
721 ggagaccaag ctggagatca aacgtaagta cctttttcca tttactgtct gaaattttgc
781 tctaattggc cagattcact tttaagtaga aattttataa aagtgggtaa atgagtaggt
841 ttgagatatg ttgttggttg caaaagttaa atgaatttag cggcaaaaag attaattgct
901 gtatattgaa tgactcaaag gggaagaaat tagcgtagat aagtaaggga gccctcggca
961 ctctaaagag cttcactgat actgttggtt acggtgtttt gcctcattgt gtgtgaaaaa
1021 tagagaaatg tattttagtc tatttcctct tttgtctgat atattattct atagcaacta
1081 taaaattcaa taacatgcac taaaaaaaca gtaagaagtt agaaaaggaa attattttac
1141 atgtaaaaga tatgactttc tggagagctt ggcagcgata taatttttag agtccacagt
1201 gagtgataaa ctatgattct acaggagtaa ggccttcaca gcctacttct ttttaaaaag
1261 tccaatttcc acattagact gaacttgaaa tgaccttcga tcaaaattgg tttaaatgaa
1321 ggaatgcatt gtttaatgat catagatttg aaggaaaata agaaatattt taagtattta
1381 aagaagaact atatgttctt ttatttcctt cagttatttg tcatattttt ataatgccaa
1441 agaggccatg gcacaactgg cgtggtctgt agatctcgtg gcggtctttt tcatggctga
1501 atgccttccg ttggccgtgc attagctccg tggggccgtg tgcctgctgg ccgctaaagg
1561 ccacagcagc cccgccacgc gcctgtctaa ctctgcagtg gccggttgtc ctgacacaca
1621 gtgatacaaa taatgccact aagggaaaga gactgtggag gacacggagc cagcatgggc
1681 gaaacagggc agaggggact tcttagaaat ttcagaaaca aaatccatgt tcgctatttt
1741 atcctcttac tgaaaacttc cattagggga ctataaagaa tgatgtacaa ttatttcaat
1801 atcctcttat catgtttatt taaattatga aagctcagtt caaaagaaag aagcatattt
1861 ataaattctt ttatggtaaa aaccacacca gcaaaaaatc aagtttaatg gcaacagtct
1921 ggccactcag atctcggtca attcactaaa tttatattaa ataccagtaa ggtgtattaa
1981 ctaataaaag taaggcaagt acgtggcatg ttgctaattt caaagattta gctgcctggg
2041 caggatgaca ttgcagttgt ataaaatatc tgctcatgta taactgcagt taacaaaaac
2101 caatataact gtatttttca ataccttaag tctgtgagag aaaaacgtaa atctagatat
2161 tttaatccca tggcctctaa aatagtttaa taatttgttg ttgctgttgt gcaccccagc
2221 taatgtcaaa catgatgttt acgaaggatt tttttggtct gcaatagctt gctagggcta
2281 ttttaggaac ctttcaaagc tcttttgaaa ctaatttaaa cctatgtaaa atgatttaaa
2341 ctgttttaaa ctattttaaa attaatttag agccttttaa aaacttttag agacttttaa
2401 actttattaa aagctaatga ggcatcttga aataattttt atattaaaaa ttaattaaat
2461 caaaataaga ttaatataat aattttataa tagttaaaaa taaaatatat tatttctaca
2521 ttttatattt atttatatat acataaaatt aattaaattt aatttacatt agaattaatt
2581 aaattaaaat ttattattaa agattagatt gctaattgtt taagatgtga acgccagatg
2641 gaaaatgtaa agctctccag gactgcccag gcggaaggtc ttcacagacc gctcttccct
2701 gctcaggggc tcgatcacag tactgtgctg ccaagtccac tgtatacagt tatggggggg
2761 gggggctaat catgaagatt caaagaggaa cataaaacag gaaagttcac tgtcttacac
2821 tgaactactt ggttaccatg ggggttagct ttgtataagc ctgtccgagc gtctgctgac
2881 ttgtcgcagg aaggattctt gattttttca ttttaacgat gctctcccac cctaggccct
2941 gactccccac agagcggggt ttcccagggc ccatctggca gctgcccgcg gtcaggagtg
3001 aagctcacca gttcctgtga ggcaggtgac ccagcttaca gctgacccct cccgagtcct
3061 cctgcaaaca ggctggcctg ggaacgggcg gccaggtgca ggtctcactg tgaggccttc
3121 aagatggtag gagagtcact ggcatgacct caggcgctga aggggtgggt gcagacacag
3181 gctgaaggcc cactctgcag ggtgggttgc ctgcctcgcc aaggaaggcc cagagagtcc
3241 tgatatcact gcccggtcct gggggagacc agggaaatga aagccgagag aggcttccct
3301 tagacgctcg ctgcctgctc tgccactgtc cccgtcttct cctaggacac agggccggga
3361 cctgttccta cttctaaact ccaaaggggt cagatgaaat gggctgtgtt ctttccccga
3421 tcactgagtc attgcagggg cagagtagag caacaacaaa gaggcctcca gtgggtcaga
3481 gagttcacac acaacaacat agactttctg aaggggcagg cggaacctgg agggaaacaa
3541 agtcatccag attctacgtc tgctcgctgc cccattgcaa cagctttggg ctgcttctgt
3601 ttgtccatcc ctaatgcact ctgtgatcat ccacatggca cccaggggag atgtccactg
3661 gtacctaagc ctcgccctct gtgcttcttc cctcctcagt tgctacgttg gcacctactg
3721 tcctcatctt cccaccatct cctgctgagc tggcaactgg aacagccacc atcgtgtgcg
3781 tggcgaataa atactttccc gatggcaccg tcacctggaa ggtggatggc atcacccaaa
3841 gcagcggcat caataacagt agaacaccgc agaattctgc agattgtacc tacaacctca
3901 gcagtactct gacactgagc agcgacgagt acaacagcca cgacgagtac acctgccagg
3961 tggcccagga ctcaggctca ccggtcgtcc agagcttcag taggaagagc tgttagagtg
4021 agacgcctgc caggcaccgc cagcgaccct gaggcccagc ctcgccgctc cctcccctca
4081 gtggacccat tcccaccaca gtcctccagc ccctcccctc ccagccctca ccccctcctt
4141 ggctttaacc gtgcgaatgt tggtgagatg gatgaataaa gtgaatcttt gcattngtga
4201 cttctctctg cttcttcatt taatggttat tagtcatggt ttccagttgc cctaaagtca
4261 cgcatttatc ctccatccac ctgcctgtgt cccggagaac atctg
//GenBank-Updates@genbank.bio.net (04/09/91)
LOCUS RABIGK1B6 4305 bp ds-DNA MAM 09-APR-1991
DEFINITION Rabbit IgK 1b6 unrearranged kappa chain J3, 4 and 5 regions (bp
1-3872) and rearranged C region (bp 3873-4305).
ACCESSION M37809 M29583
KEYWORDS constant region; germline; immunoglobulin kappa chain;
immunoglobulin light chain; joining exon; processed gene.
SOURCE Rabbit cell line RMH H158 DNA.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 4305)
AUTHORS Dreher,K.L., Asundi,V., Wolf,B. and Bruggeman,L.
TITLE rabbit ig k1b6 gene structure
JOURNAL J. Immunol. 145, 325-330 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS join(125..160,3702..4016)
/product="Ig kappa chain"
/gene="IgK"
/codon_start=125
/partial
CDS join(414..449,3702..4016)
/product="Ig kappa chain"
/gene="IgK"
/codon_start=414
/partial
CDS join(707..743,3702..4016)
/product="Ig kappa chain"
/gene="IgK"
/codon_start=707
/partial
BASE COUNT 1230 a 908 c 986 g 1180 t 1 others
ORIGIN
1 gatgaggcac agaggaggga aaactgtctg agatttccaa gtgaaaataa gttcctcggg
61 gagagcgttg ccgccttgtc agggagggtt taatggaggg agaaggtaaa gggagccacc
121 gtgatccact cttggcccag ggaccaaact ggaaatcaaa cctaagtccc tttctgtcca
181 actgtgaggt cttggtcccc tggatcacct gggcaagttt gtgatgtttc agttaaatga
241 gccattcctg gcgaccccaa aagtaaatag aagaaaatct tcaaaagcgg agaagacaga
301 aatttggggg tttgggagaa taggagagaa acaacagaag tttctccaca attgccgtgt
361 ggtgggactg gccgcaaagg gaggtttttg tgaggggtgg gatgacagag tgacttgctt
421 ttggctcagg gaccatggtg gagatcagat gtaagtgcac tttcccagtc cttttccgta
481 ctaagttggt aaatgtggga tttgcgcatt tgggagatga gttaaggtcg atccggaggg
541 gaatggaatt tttccaaaaa cacggatggg tagggagcag aatatctgtt catctcaaat
601 agagagcaaa gagctagcga gtggccaaat tctgtctgtc agtctaatga gcttgggagc
661 agtcagaggt ttttgttgag ggaaagcaat aaagctaatt ccatgaatca cctttggcga
721 ggagaccaag ctggagatca aacgtaagta cctttttcca tttactgtct gaaattttgc
781 tctaattggc cagattcact tttaagtaga aattttataa aagtgggtaa atgagtaggt
841 ttgagatatg ttgttggttg caaaagttaa atgaatttag cggcaaaaag attaattgct
901 gtatattgaa tgactcaaag gggaagaaat tagcgtagat aagtaaggga gccctcggca
961 ctctaaagag cttcactgat actgttggtt acggtgtttt gcctcattgt gtgtgaaaaa
1021 tagagaaatg tattttagtc tatttcctct tttgtctgat atattattct atagcaacta
1081 taaaattcaa taacatgcac taaaaaaaca gtaagaagtt agaaaaggaa attattttac
1141 atgtaaaaga tatgactttc tggagagctt ggcagcgata taatttttag agtccacagt
1201 gagtgataaa ctatgattct acaggagtaa ggccttcaca gcctacttct ttttaaaaag
1261 tccaatttcc acattagact gaacttgaaa tgaccttcga tcaaaattgg tttaaatgaa
1321 ggaatgcatt gtttaatgat catagatttg aaggaaaata agaaatattt taagtattta
1381 aagaagaact atatgttctt ttatttcctt cagttatttg tcatattttt ataatgccaa
1441 agaggccatg gcacaactgg cgtggtctgt agatctcgtg gcggtctttt tcatggctga
1501 atgccttccg ttggccgtgc attagctccg tggggccgtg tgcctgctgg ccgctaaagg
1561 ccacagcagc cccgccacgc gcctgtctaa ctctgcagtg gccggttgtc ctgacacaca
1621 gtgatacaaa taatgccact aagggaaaga gactgtggag gacacggagc cagcatgggc
1681 gaaacagggc agaggggact tcttagaaat ttcagaaaca aaatccatgt tcgctatttt
1741 atcctcttac tgaaaacttc cattagggga ctataaagaa tgatgtacaa ttatttcaat
1801 atcctcttat catgtttatt taaattatga aagctcagtt caaaagaaag aagcatattt
1861 ataaattctt ttatggtaaa aaccacacca gcaaaaaatc aagtttaatg gcaacagtct
1921 ggccactcag atctcggtca attcactaaa tttatattaa ataccagtaa ggtgtattaa
1981 ctaataaaag taaggcaagt acgtggcatg ttgctaattt caaagattta gctgcctggg
2041 caggatgaca ttgcagttgt ataaaatatc tgctcatgta taactgcagt taacaaaaac
2101 caatataact gtatttttca ataccttaag tctgtgagag aaaaacgtaa atctagatat
2161 tttaatccca tggcctctaa aatagtttaa taatttgttg ttgctgttgt gcaccccagc
2221 taatgtcaaa catgatgttt acgaaggatt tttttggtct gcaatagctt gctagggcta
2281 ttttaggaac ctttcaaagc tcttttgaaa ctaatttaaa cctatgtaaa atgatttaaa
2341 ctgttttaaa ctattttaaa attaatttag agccttttaa aaacttttag agacttttaa
2401 actttattaa aagctaatga ggcatcttga aataattttt atattaaaaa ttaattaaat
2461 caaaataaga ttaatataat aattttataa tagttaaaaa taaaatatat tatttctaca
2521 ttttatattt atttatatat acataaaatt aattaaattt aatttacatt agaattaatt
2581 aaattaaaat ttattattaa agattagatt gctaattgtt taagatgtga acgccagatg
2641 gaaaatgtaa agctctccag gactgcccag gcggaaggtc ttcacagacc gctcttccct
2701 gctcaggggc tcgatcacag tactgtgctg ccaagtccac tgtatacagt tatggggggg
2761 gggggctaat catgaagatt caaagaggaa cataaaacag gaaagttcac tgtcttacac
2821 tgaactactt ggttaccatg ggggttagct ttgtataagc ctgtccgagc gtctgctgac
2881 ttgtcgcagg aaggattctt gattttttca ttttaacgat gctctcccac cctaggccct
2941 gactccccac agagcggggt ttcccagggc ccatctggca gctgcccgcg gtcaggagtg
3001 aagctcacca gttcctgtga ggcaggtgac ccagcttaca gctgacccct cccgagtcct
3061 cctgcaaaca ggctggcctg ggaacgggcg gccaggtgca ggtctcactg tgaggccttc
3121 aagatggtag gagagtcact ggcatgacct caggcgctga aggggtgggt gcagacacag
3181 gctgaaggcc cactctgcag ggtgggttgc ctgcctcgcc aaggaaggcc cagagagtcc
3241 tgatatcact gcccggtcct gggggagacc agggaaatga aagccgagag aggcttccct
3301 tagacgctcg ctgcctgctc tgccactgtc cccgtcttct cctaggacac agggccggga
3361 cctgttccta cttctaaact ccaaaggggt cagatgaaat gggctgtgtt ctttccccga
3421 tcactgagtc attgcagggg cagagtagag caacaacaaa gaggcctcca gtgggtcaga
3481 gagttcacac acaacaacat agactttctg aaggggcagg cggaacctgg agggaaacaa
3541 agtcatccag attctacgtc tgctcgctgc cccattgcaa cagctttggg ctgcttctgt
3601 ttgtccatcc ctaatgcact ctgtgatcat ccacatggca cccaggggag atgtccactg
3661 gtacctaagc ctcgccctct gtgcttcttc cctcctcagt tgctacgttg gcacctactg
3721 tcctcatctt cccaccatct cctgctgagc tggcaactgg aacagccacc atcgtgtgcg
3781 tggcgaataa atactttccc gatggcaccg tcacctggaa ggtggatggc atcacccaaa
3841 gcagcggcat caataacagt agaacaccgc agaattctgc agattgtacc tacaacctca
3901 gcagtactct gacactgagc agcgacgagt acaacagcca cgacgagtac acctgccagg
3961 tggcccagga ctcaggctca ccggtcgtcc agagcttcag taggaagagc tgttagagtg
4021 agacgcctgc caggcaccgc cagcgaccct gaggcccagc ctcgccgctc cctcccctca
4081 gtggacccat tcccaccaca gtcctccagc ccctcccctc ccagccctca ccccctcctt
4141 ggctttaacc gtgcgaatgt tggtgagatg gatgaataaa gtgaatcttt gcattngtga
4201 cttctctctg cttcttcatt taatggttat tagtcatggt ttccagttgc cctaaagtca
4261 cgcatttatc ctccatccac ctgcctgtgt cccggagaac atctg
//