GenBank-Updates@genbank.bio.net (04/09/91)
LOCUS SA2NORA 600 bp ds-DNA BCT 09-APR-1991
DEFINITION S.aureus plamsid pSA209 norA gene, 3' end.
ACCESSION M62960
KEYWORDS norA gene; quinolone resistance.
SOURCE S.aureus fluoroquinolone-suceptible plamsid pSA209 DNA.
ORGANISM Plasmid pSA209
Prokaryota; Bacteria.
REFERENCE 1 (bases 1 to 600)
AUTHORS Ohshita,Y., Hiramatsu,K. and Yokota,T.
TITLE A point mutation in norA gene is responsible for quinolone
resistance in Staphylococcus aureus
JOURNAL Biochem. Biophys. Res. Commun. 172, 1028-1034 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS <1..482
/gene="norA"
/codon_start=3
mutation 400..400
/phenotype="Asp to Ala confers quinolone resistance"
/note="replace(400,`c')"
BASE COUNT 185 a 73 c 113 g 229 t
ORIGIN
1 cagctgacaa ggtaaattat tcacctaaag atatttcgat tgctattacg ggtggcggta
61 tatttggggc acttttccaa atctatttct tcgataaatt tgtgaagtat ttctcagagt
121 taacatttat agcttggtca ttattatatt cagttgttgt cttaatatta ttagtttttg
181 ctaatggcta ttggtcaata atgttaatca gttttgttgt cttcataggt tttgatatga
241 tacgaccagc cattacaaat tatttttcta atattgctgg agaaaggcaa ggctttgcag
301 gcggattgaa ctcgacattc actagtatgg gtaatttcat aggtccttta atcgcaggtg
361 cgttatttga tgtacacatt gaagcaccaa tttatatgga tataggtgtt tcattagcag
421 gtgttgttat tgttttaatt gaaaagcaac atagagcaaa attgaaagaa caaaatatgt
481 agcataagta ttttggtgta tattgatata aagtaaagcg taatattatg aatgattagt
541 caatcgtttt tcttatgaat ttattaagaa aattcgatgc tttacattta aaaagattcg
//