GenBank-Updates@genbank.bio.net (04/11/91)
LOCUS RATTCBC1 8040 bp ds-DNA ROD 11-APR-1991
DEFINITION Rat T-cell receptor beta-chain complex, segment 1.
ACCESSION M63793
KEYWORDS T-cell receptor beta-chain.
SEGMENT 1 of 3
SOURCE R.norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Williams,C.B., Blankenhorn,E.P., Byrd,K., Levinson,G. and
Gutman,G.A.
TITLE Organization and nucleotide sequence of the rat T-cell receptor
beta-chain complex
JOURNAL J. Immunol. (1991) In press
STANDARD full staff_review
COMMENT Genomic sequence of the rat T-cell receptor beta chain constant
region complex, including D-beta-1, J-beta-1.1 through 1.6, and the
four exons of C-beta-1 (see RATTCB2A and RATTCB2B for the C-beta-2
regions). Ten cryptic rearrangement signals, described in
reference [1], are noted, as well as the 3' end of an L1Rn LINE
repetitive element. This sequence is approximately 2.8kb 5' of
RATTCB2A.
FEATURES Location/Qualifiers
misc_feature 238..248
/product="D beta 1"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 905..952
/product="J beta-1.1 (aa at 3)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 984..1011
/function="cryptic rearrangement signal #1"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 1044..1091
/product="J beta-1.2 (aa at 3)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 1343..1392
/product="J beta-1.3 (aa at 2)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 1849..1900
/product="J beta-1.4 (aa at 3)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 1926..1952
/function="cryptic rearrangement signal #2"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 2124..2173
/product="J beta-1.5 (aa at 2)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 2583..2653
/product="J beta-1.6 (aa at 2)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 2604..2631
/function="cryptic rearrangement signal #3"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 2859..2887
/function="cryptic rearrangement signal #4 (13bp spacer)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 3221..3247
/function="crypic rearrangement signal #5"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 4117..4144
/function="cryptic rearrangement signal #6"
/citation=J. Immunol. ??, ??-?? (1991)
exon 5057..5434
/product="C beta-1 exon 1"
/citation=J. Immunol. ??, ??-?? (1991)
exon 5868..5885
/product="C beta-1 exon 2"
/citation=J. Immunol. ??, ??-?? (1991)
exon 5980..6086
/product="C beta-1 exon 3"
/citation=J. Immunol. ??, ??-?? (1991)
exon 6403..6423
/product="C beta-1 exon 4"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 6494..6522
/function="cryptic rearrangement signal #7"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 6553..6579
/function="cryptic rearrangement signal #8"
/citation=J. Immunol. ??, ??-?? (1991)
polyA_signal 6623..6628
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature 6804..6894
/product="ID repetitive element (w/ 10bp direct repeats)"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 7383..7410
/function="cryptic rearrangement signal #9"
/citation=J. Immunol. ??, ??-?? (1991)
misc_feature (7441.8040)..>7441
/product="L1Rn LINE repetitive element"
/citation=J. Immunol. ??, ??-?? (1991)
misc_signal 7452..7478
/function="cryptic rearrangement signal #10"
/citation=J. Immunol. ??, ??-?? (1991)
BASE COUNT 2327 a 1702 c 1817 g 2176 t 18 others
ORIGIN
1 aaacagcatt tnaatgacat caggctccaa gaacaaagaa cattcaaagt agaacagggg
61 ttaaggagga aacccctgca ttagctcact tcttatcacc accttgcaca atggtggcga
121 tgtcatcttc cttatctttg actcccctca gaggagcagc ttctctggtg gtttcttcca
181 gccctcaagg ggtagaccta tgggagggtc ctttttgtat aaagctgtaa cattgtgggg
241 acagggggca cggtgattca attctatggg aaacctttac aaaaaccttt ctgtctgtcc
301 caaggcccac agtctgctac tcttcctctg ggtcacaaat ctaaatccat ttacatccaa
361 aatgcttcta cttcacctct gcttcctgcc aggccaagat tgtggagaag aatggggctg
421 tcccagagca gaaacctacg cagaatgatc acaagcataa gaagagaggc ctagtggcct
481 agaggcagaa gatgcaggaa gagcctcttc tcccaacttc cataaaacag accaccacca
541 tcagtggaca ggtgaaacag agatgaacag gtctacagct ttaaaaaaaa gccataaaga
601 tctcagctct agaggaatat caacatctct ctgggaatct gctctctgaa gggctacctc
661 acttcagtgg accttcagag agagaatata tatggtatgt tattcacaaa aggggatgta
721 ggtcccaatg gatggaatct accatgttct acattgctac aagtctaaca tcaaaatgtt
781 cttttgtgca atacttgtca tgcacacaag gctattattc ctcctagggt cctctcgaca
841 ctagctggga tgagtttctc gtcacatctt aagattattt tcctcctcac cctatagcac
901 tgtgcaaaca cagaagtctt ctttggtaaa ggaacgagac tgacagttgt aggtaagata
961 tctttaaggc aaatttccaa atctgtcttt ggacaaagcc tgtcctctgt gtccatatta
1021 gagagtatct gtattctgat gtgcaaacta tgactacacc tttggcccag ggaccaggct
1081 tttggtaata ggtaaggcct gagggtcttt gggtgtggga taaaaggtgt aatactgtcc
1141 aggaaataag agaaaggatc cagctcatgg ttccttcttg aggaagtcta tctcatgtct
1201 gggactacat tcaaaggagg ttgaatccac aaagttagac tgaatgtttg tgactgagtc
1261 ctcctagggt ggagggtagg aaagagaaaa gagaagggct cacagagagt gaagggtttt
1321 gaattggacc tgggaggctg tgttctggaa atgcgctcta ttttggtgaa ggaagccggc
1381 ttcttgtcgt aggtaagtta gggccaaatg gctgggtacc agatgaaatt tctctctgag
1441 gtgtccaggt tgcaaggtac ttctataaga aagaactaaa ttcctctgct catgcatgtg
1501 agaggggttg aatgcccatc tcccatattt tacatgctgg ttatatgaaa cctgggtacc
1561 ctgttaaatg ccggcaagct caactaggag tcagcctcgt gtactgttca tagtcctgct
1621 gtttgaccct cacatacagg cagaaaacag gctttgggga ggaggaggag gatgtacaga
1681 tcattaggaa aacggactgc caattatatt agttaatact gcacacctgt ctgtcctact
1741 ccctggggat aaaaccttcc tcaggaatga gggaagctaa ctggcagtgg gcacagggag
1801 gaaggacaga aagcaggagg aagttttaca atcaggcttt aatgttgtgt ttccaatgaa
1861 agattgtttt tcggccatgg aaccaagctg tctgtcctgg gtatgtaaaa attttctttc
1921 tcaggaaggt ttgttgtaag cctagaggtg tggggaactc ctcagacaag gaaaagacaa
1981 aaagacgcag cctgggctgt ggttcaaaga ggaagaaagg ctggtgaatg tgcctggacc
2041 cctggggatt ctgtgtagag tcctgcctca gggaagggcc ccatcagatc cttgggagtt
2101 tgccaccctt gtattgtact gtgtaacaac caggcccagt attttggaga ggggactcgg
2161 ctctctgttc taggtaagct atgggactaa agtggtggga gcaccgtccc ttggattcag
2221 ggtttctgca tccccagagc tgggtagaag gggctggggg attgagttat tccttttctt
2281 gctaggttct aaagggggcc tctgcctccc ttacgaggag atgaatcagt aactgtttct
2341 tttcccctga gtctctgcag tctaggagca gtctcctgcc ttctgacatt tctgtttgca
2401 tagatgtgct tcttctgagt cctttcctcc agtctccctc ctgtcacttg tctcatggca
2461 ttactggagt ctggaattct tcctgcaggc agagagacag tcatccagat ctcagggagc
2521 taagagtagc tctctagctt tgggaccgcg ggtaggtttt accaaggcca ccagcaactg
2581 tgtttctata attcgcccct ctactttgca gcaggcaccc ggctcactgt gacaggtatg
2641 ggggttccat tcctgactgg aggggttatg cctgtgttgg atcaacatgg tctgggaaag
2701 gaacttaggt ataagataag acagagtcat cccttcccat ttagaaccct ctactcttct
2761 acttccccaa gcctggtagc tttctcttct ctgggtttgt tttctctttg tggtctcgga
2821 aagccttgct tcggagcttt gagtcttctt tctcttgttt ttattctttg gactactgtc
2881 gtctgtgcct tccgagcgga tgcattactt cgctttctct ctatagcctc atctccactc
2941 tttccattct ctttcccctt ctgcactgtt gggttggttt ggtacataga actctgtctt
3001 atttaaaata ttgacactga cctcctgtgc agacttctgc tgcctccttc atcttctgcc
3061 tctatcggtt tctgaggaca catgtctgtc ttccttgtgt gatagaaagg gctggagggc
3121 agaggggatc aggtcttggt ggtatcagag tgacctgggc actaatcctg agcaatggca
3181 taagtctgtc atagcactac aggaactgta gctgcctaca gaactttgga gtatattata
3241 ctccgtggat atctcagggt tagatatgaa aaagcttata actagaaagt gatatattag
3301 caataaatta tgtatgatga agagaaaata aaggtcttga gactccaggt ctgtcttgga
3361 ataataagct aatgaaaacc taaaataagc aatatcatac ttgggaggaa gcagaaaggc
3421 taacaggcat ggggagtggg taggaaagat atgaggtctg gaaaatacaa gaaaaggtgg
3481 aagaatgtaa cacctcggtc ctcccaggat tggtagcttc catagatatt gtctagtaga
3541 caggatccat gccatgaaaa ttaaaggaaa ctactaagca ctggtttcaa aggccnnnng
3601 ctcaaagnnn nggaaaatgc atagagtgat atttttnnnn gngngaagtt tcaggcaatc
3661 ccagactcta taagacacac aaaaaaaaaa tagaaaggac tgttttatgt ttaaaattat
3721 tgatnttgtt tgatttttac ttttgagaac ttcataaata agtagtgatt ctacatcctt
3781 cttcctcctt tcnctctctc ccaattcttt taaaggattc aaaggtcaca ttatgtgact
3841 acatttattt caattattga ttatccttca agccactgtt tgtctttctc caaactcatt
3901 tctcaatttc ccggacaagt cctcaacttc agacaaagaa gaaagatctt atgttatcct
3961 gtttgtacac cagaacctta ctttaaggtc agaacagagc caaagaggaa gaccattgaa
4021 ctctacatca agggaggagg cttggaggac atatgtggat tttgcatcta ttgtgtcttg
4081 gggcaggggt cattcatttc aataatccta ggagtatttt tctgtcctgt cttctaagca
4141 tgtggctgga tccaggcctt tctggtggag acctgcttct gaaatgaccc ttgtacttta
4201 ttatttgttt acaggaattt ttcactacat taaagaatac aatgttaggt tgtgaacntt
4261 gaattctgaa actcaccagg gagacttgtt gagcactgaa aaaataaaag ttcaacctat
4321 gaatactatc ttccatggga ttgcagcttt cctatgcaag ccaccacagc tttctcacat
4381 ctcagtgtag aagtggatgt ggaacatcgg ataggctaac agccagagac aagctggaac
4441 ctcaaagcaa gttgcgtgca gtgggggagg aggttgcatt gagcaagtat tcagaaactc
4501 agagatgtct ctggatgttg tgtggaaagt gtcgatttta ggtaacgaaa gtttatacta
4561 tatagaatga cctaaataca ttgatatatc cactttaccc caaaaagaaa aataataata
4621 aggagaaaaa aaaccttagt tcttaggatc atgacattac tatgacatct ttgtcttaaa
4681 attcaatatc actcaaagcc tctgtttcga atagccatgc atagattccg gtttcttaaa
4741 aactactggg tgtattcttt ttaaccagtg atcagtgttc aagtacatga gtcattacaa
4801 gaaagtgaaa aatccaaggt accattccac cataggaaag tgtggggaga gagtaaacaa
4861 agcatatact tagaacaatc tataaagaag agggaatgcc aagggagacc agaaacagaa
4921 ttggacaagg acaaaaaaca agcagaacct gctacaacat agttgtactt tataatgacc
4981 atttccagcc ctctcttaca aatccaagct tggttcagac agctctcaga catctcctgt
5041 tctcttcatt tttcagagga tctgaaaacg gtgactccac ccaaggtctc cttgtttgag
5101 ccatcagaag cagagatcgc agacaaacaa aaggctaccc tcgtgtgctt ggccaggggc
5161 ttcttccctg accatgtgga gctgagctgg tgggtgaatg ggaaggagat ccgcaatggg
5221 gtcagcacag accctcaggc ctacaaggaa agcaacaaca tcacctactg cctgagcagc
5281 cgcctgaggg tttctgctcc cttctggcac aatcctcgca accacttccg ctgccaagtg
5341 cagttctatg ggcttacaga ggaagacaac tggtcagagg actcacccaa acctgtcaca
5401 cagaacatca gtgcggaggc ctggggccga gcaggtaagg gggccttggg gagctggtaa
5461 gaaaatgaca tcagtagtgc caaagaaaaa cggaaagatg caggtgaaaa gccaggaagt
5521 caggatacag aaaatacact ggaaagtgat aaaaagccta ccaagaagat aaactagaca
5581 actgtgtata attctcactc cagatcctca ttctgtcagc cttacatgta agatctccag
5641 tctatgccac ttgtgcagct cagtatccga atcattagct ttggtgccta tgccatgggt
5701 tttaagaaca cttggtacaa cagaagaggg atgcttctgg gacctcctgg ggggaggggt
5761 aatctgggcc tatcaaacta tgctagctcc taggatgact taattttcaa tcttcttaat
5821 aaaaaggtgt ctcatccatt ttcctctctc tctttctatt ctttcagatt gtaggattac
5881 ctcaggtaag ccacttaact ctttcttcac ctctcatgat cttgactgta gaactagcta
5941 cctggccaac ggacttacct gctctccttt tgtcaacagc atcctatcaa caaggggtct
6001 tgtctgccac catcctttat gagatcctga taggaaaagc caccctgtat gctgtgcttg
6061 tcagtacgct ggtagtgatg actatggtaa ggaacgagca gatggacctt acaggggagg
6121 tgacacatgg aacacaagac acttacatcc aggggcttaa gggctcttcc aggattagat
6181 ggaagcagta gagaaagctc tgctcccatg ccattaagga caagaagaaa tttcaaagaa
6241 ttttagtgaa tgatctacag agaggacatg ctatgataat tcaaaatgcc caagggatgt
6301 tttagtagct ctataatttg tcagaacaat gggccttcct acattctttc aagccccact
6361 atgcatggcc attggaaaac ctaaaatgct tctcatccgc aggtcaaaag aaagagttcc
6421 tgaagccaga cctgaaggtg aatccaagag cttacaaccc attgtggtgt tgatacagat
6481 tttcttctac tggcgcttct gaagagccta ttctcctttg tggatcccaa agtctgccta
6541 gtcatgtata tttgtgtttg tatgtttgaa atccttgtgg cctggagagt gcctagcaca
6601 cttacaatta gtaaccataa ccaataaaac atgttctaga atggcctgac tctctctggt
6661 gtgtgtagat atctttattt cttttctctc cccaaactcc ttgatcaatt tatgattaga
6721 aaagaagaga tattcaagaa aaatgatgcc catccagggt aagagaagtg aaggccccac
6781 cctcaaatta acagatgatg attggggttg gggatttagg tcagtgatag agcgcttgcc
6841 tagcaagcgc aaggccctgg gtttggtccc ctgctctgga aaaaaaaaaa aaaagatgat
6901 gattaagttt ggaaggtagt gacagaaact aaaaattctc aagagagaag gacagaggtc
6961 ctgagtacag gaagtctctt aacttcaaaa ccaaaccaac taaacaaaca aaagatgagt
7021 gctctggggg acagcagcta cagattacac aaatgtatcc acctgcaact tgtcatgccc
7081 ctgtggctaa caaggcttgg ttccatgtgt gtcacctatc ttcctttagg ccttttactg
7141 aacacatgtg ttcattcacc aagcagcttt cctagatgat tacccatgac aatgcactga
7201 cttggaaaac tatattccaa tggaagatgt gtctttcact taaggtacaa atcgttgtta
7261 aattataccc cggtgaaatg gagggatgta aactatatca cacaagcgtg cctagttgta
7321 cagaacttag agcttcctat aagcaagagc aatacctatt tctacatcta gaaagtctgc
7381 atatctcttg atctcgctgc agccattgtg gagtagttgc gatccttaag atggcataaa
7441 taaaactgca aagcttctgt aaggcaaagg acactgtggt taggacaaaa cggcaaccaa
7501 cagattggga aaagatcttt accaatccta taacagatag aggccttata tccaaaatat
7561 acaaagaact caagaagtta gaccgcaggg aaacaaataa ccctattaaa aaatggggtt
7621 cagagctaaa caaagaattc acagctgagg aatgccgaat ggctgagaaa cacctaaaga
7681 aatgttcaac atctttagtc ataagggaaa tgcaaatcaa aacaaccctg agatttcacc
7741 tcacaccagt gagaatggct aagatcaaaa actcaggtga cagcagatgc tggcgaggat
7801 gtggagaaag aggaacactc ctccattgtt ggtgggattg cagactggta aaaccattct
7861 ggaaatcagt ctggaggttc ctcagaaaat tggacattga actgcctgag gatccagcca
7921 tacctctctt gggcatatac ccaaaagatg cctcaacata taaaagagac acgtgctcca
7981 ctatgttcat cgcagcctta tttataatag ccagaaactg gaaagaaccc agatgccccc
//