GenBank-Updates@genbank.bio.net (04/19/91)
LOCUS HUMSCL7 3890 bp ds-DNA PRI 19-APR-1991
DEFINITION Human stem cell leukemia gene product, exon 6.
ACCESSION M63589
KEYWORDS stem cell protein.
SEGMENT 7 of 7
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3890)
AUTHORS Aplan,P.D., Begley,C.G., Bertness,V., Nussmeier,M., Ezquerra,A.,
Coligan,J. and Kirsch,I.R.
TITLE The SCL gene is formed from a transcriptionally complex locus
JOURNAL Mol. Cell. Biol. 10, 6426-6435 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron order(M63584:104..111,1..8)
/number=V
/gene="SCL"
mRNA join(M61103:1..169,M63572:9..126,M63572:429..584,
M63576:9..455,M63584:9..103,9..3890)
/note="found in HEL K562 cell line"
/product="stem cell leukemia gene product"
/gene="SCL"
mRNA join(M61103:1..169,M63572:429..584,M63576:9..455,
M63584:9..103,9..3890)
/note="found in HEL K562 cell line"
/product="stem cell leukemia gene product"
/gene="SCL"
mRNA join(M61103:1..169,M63584:9..103,9..3890)
/note="found in HEL K562 cell line"
/product="stem cell leukemia gene product"
/gene="SCL"
mRNA join(M61104:1..42,M61105:9..140,M63572:429..584,
M63576:9..455,M63584:9..103,9..3890)
/note="found in HEL K562 and HSB-2 Jurkat cell lines"
/product="stem cell leukemia gene product"
/gene="SCL"
mRNA join(M61104:1..42,M63572:429..584,M63576:9..455,
M63584:9..103,9..3890)
/note="found in HEL K562 and HSB-2 Jurkat cell lines"
/product="stem cell leukemia gene product"
/gene="SCL"
CDS join(M63576:10..455,M63584:9..103,9..463)
/function="hematopoietic differentiation"
/product="stem cell leukemia gene product"
/gene="SCL"
/codon_start=10
exon 9..3890
/gene="SCL"
BASE COUNT 885 a 939 c 999 g 1067 t
ORIGIN
1 atctgcaggt ccccacacca aagttgtgcg gcgtatcttc accaacagcc gggagcgatg
61 gcggcagcag aatgtgaacg gggcctttgc cgagctccgc aagctgatcc ccacacatcc
121 cccggacaag aagctcagca agaatgagat cctccgcctg gccatgaagt atatcaactt
181 cttggccaag ctgctcaatg accaggagga ggagggcacc cagcgggcca agactggcaa
241 ggaccctgtg gtgggggctg gtgggggtgg aggtggggga gggggcggcg cgcccccaga
301 tgacctcctg caagacgtgc tttcccccaa ctccagctgc ggcagctccc tggatggggc
361 agccagcccg gacagctaca cggaggagcc cgcgcccaag cacacggccc gcagcctcca
421 tcctgccatg ctgcctgccg ccgatggagc cggccctcgg tgatgggtct gggccaccag
481 gatcagccag gagggcgttc ttaggctgct gggatggtgg gcttcagggc aggtggggtg
541 agaattgggc ggctctgaag caaggcggtg gacttgaact ttcctggatg tctgaacttt
601 gggaagcctt tactgaccct ggggctggct tttctgtttc ctgtaccagt aggagatcag
661 aaaaatggag caaagtggta ggtacttttt gtgaagacgg cacggtcttc cctcttccct
721 cagtcccaaa tccttcccaa gtaagaggct ggagttgtca ctgcttttgg cctggagttt
781 gggatccctg tctttcctaa gacctggggt tgtcagctct catctgaggc atccagcagt
841 ctctgccttg cctttagccc ctcccaagct ggctggggtg gcctgtgtgg ccacttctgt
901 ccatatttat aggtacccaa tagctgccca tttcgtgagc cccatcttca cccaggccta
961 tgttgatcca tccagcttgc cagatgctgc agagtcacaa gcctcgaggt gccttcttca
1021 gggcctggtt gaagaagatg atcagtggac agtctgctct agatgagctg ggccggaggg
1081 tcaggaaacc cagtcgccct tacttcttgc cctggggatc aaagttctgc tttctcccca
1141 atgagacttg ccttcctaag cctgtggctg tggagaccat gtctgcagcc ctgagaaagc
1201 cctgtcgggc tttgtgtgaa ggcagagaaa gggacaatga tagtagagtg atatggagca
1261 agagatattt tgggcatgtg ggcttcaact cctcgacatc actgttcatg ctggcgagtg
1321 aatgccagtg tgctgatggg cgtacgctgg tgctgagtag atgcgcagcc ccatctgtgc
1381 attctcctgg atgcttagag ggatttcttt gctgtaagat gtctgtttgc tgatggtctg
1441 gtctatgttc cgaattgagc acaaaacctg tcctatgaat gctttgcatt tggaattttt
1501 gcttgacttc agttattggt ggaatcttta gcgctcaata ggaccaggat ccagcctcac
1561 ttctagggta tgggaaatcc aatcagagac caggccctgg ctagacccaa acatatgcac
1621 attcacttag cagaacctta aacacccctc agttgtgcag cttttggtca tcaagggtgc
1681 gtctgggagg ttggtttaat gcaatagaag tgctcccctc tgaaagttgt acatgaaatt
1741 tttgtaaatc acatccttat ccttcatctt ttaaagaaat aaccactgca agtccttttg
1801 taaagtgaag aatccttttg tagaatgaac cactgcccct tcattgattt cctgtgtcaa
1861 tccagatggt gggatgtggt tttcttaagg tgaggcctgt ctgtgacctg catctaagcc
1921 catgggacaa attgcacaga agtcctgtat gtctgtcatt gtacccttaa gtcaccctag
1981 ccctctccct ctaggctctg ccttcgaggt cagaggagag atagcctgtg gccctgtcct
2041 gccatgcaag aactcatcac tgtggctgtc tggaaagccc ccccttatag tttgggcttc
2101 agcctagtgg cttgtcctca ccatgatggg gccctaattc agccatgtac agacagagaa
2161 tatgtctgct cctttcccct tccttttaag taaggtccaa ttctcgagct tggggcaaca
2221 ttgttcacct ttgtagcact caggctctcc attcaatttc aggctcccca gatcatgttt
2281 tggtgaaaat tagggttggt tcctttccaa cgtttggaag atcctgtgag gagccccatc
2341 tgtctaaaga tagagtcatt gctgtaggat ctaaggctgt ttgcttcacc gtggattcgc
2401 ttgagttagg aatgagaagt agccacagta tggatgggtg gatgggtttt atgagatgga
2461 tcacatattt tattaagaac tcaaacttct ggctccctct tctttcagac ttgccatgtg
2521 actctggctt ggcctatctc ctagggctat ggtgtggact gaatgggatc atgaaagtag
2581 acagttttga gaacgtaaag aactttttct tttccctcaa tctcaatcct gcagtggggt
2641 ttcgcagcct gagtccacga cctaggcagt aggccggtgt gcctgactgc ccagcatttg
2701 ggtaatttag attgtaaacc gctttggcct gagttattga gattgtcctc atttctccag
2761 attatctatt tgtgtgtgtg tgtgtgtgtg tgtgagagac ggtgtcttgt tctgtcactc
2821 aggctggagt acagtggtgc catcattgct gtctgcagcc ttgaactctg ggctcaagca
2881 atcctctcac ctcagcctcc cgagtaggga ggaccacagg tgtgagccac cacacctggc
2941 taatttttac tttttttttt ttttggtaga gatggagtct tgctatattg cccaggctgg
3001 tcttgaagtc ctggcttcag gcaattctcc tgcctttgcc tccagaagca ctgggatcac
3061 aggtgtcagc cattgcaccc agcccagatt gtcttaattt ctatcttgtt ccaaggccag
3121 ggacagtaat aagaatggaa aagagatatg ggaacactgg cagactgtgt aaaatgtaat
3181 gcaactaccc aaaacaagcc tggtaggaaa gggcaagtct ttaggtcttt gtaagaacta
3241 aagaagatct gtaattttta ttttcaccct ctgtacccca tgaccttatc cttcctctcc
3301 ttccttgtta cccatgaaaa actggcaaca ttccaagaat agcatctgta caaaggggaa
3361 agaacataaa ggtaaaacaa aacaaaacaa cattttgaga acaaagatga ccataaccac
3421 tgaagggaat cacatctttt aagacaaatt catattcttt tatttgttat ggcagatgac
3481 aagatggtac aacctttatt cttttccaaa ataaaacaaa gggcacagca tctgtagtca
3541 gccgacaact ctttcggcct tttgggggtg ggtctggccg tacttgtgat ttcgatggta
3601 cgtgaccctc tgctgaagac ttgccccctg cccgtgtaca tagtgcattg tttctgtggg
3661 cgggcccagc actttccgtc aacgttgtac tgtatgtgat gaattgcgtt ggtctctgca
3721 tttttctgca gaagaggagt aaccgctcca ggtaccttga cctttgtaca gcccagaggc
3781 caacactgtg ggtgtgtgac tctttagcaa aaaaaaccca tgtggtgatg atgtgtctat
3841 atatgtgagg atgtatcggg aagatttcta aataaaagtt ttacaaaggg
//