GenBank-Updates@genbank.bio.net (04/25/91)
LOCUS RATS14 4809 bp ds-DNA ROD 25-APR-1991
DEFINITION Rat S14 protein gene, 5' end.
ACCESSION M33553
KEYWORDS S14 protein.
SOURCE Rat (strain Sprague-Dawley) liver DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 4809)
AUTHORS Jump,D.B., Bell,A. and Santiago,V.
TITLE Thyroid hormone and dietary carbohydrate interact to regulate rat
liver S14 gene transcription and chromatin structure
JOURNAL J. Biol. Chem. 265, 3474-3478 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
promoter 1409..1809
/note="thyroid hormone response element"
/gene="S14"
/evidence=EXPERIMENTAL
promoter 2205..3850
/note="tissue-specific response element"
/gene="S14"
/evidence=EXPERIMENTAL
promoter 2715..3850
/note="retinoic acid response element"
/gene="S14"
/evidence=EXPERIMENTAL
promoter 2715..3850
/note="glucocorticoid response element"
/gene="S14"
/evidence=EXPERIMENTAL
promoter 3850..4301
/note="promoter elements"
/gene="S14"
/evidence=EXPERIMENTAL
TATA_signal 4288..4294
/gene="S14"
exon 4315..4809
/number=1
/gene="S14"
CDS 4338..4790
/product="S14 protein"
/gene="S14"
/codon_start=4338
BASE COUNT 1161 a 1142 c 1303 g 1203 t
ORIGIN
1 ggatcctgaa ttgcaggggg agtaggaaag gcctggcctt gccttccacg ggttcccaga
61 taaagtgaca agtgtggtct ggtgacagag ttttaaattc tcagagcctt atagtaagtg
121 ctaaatgtgg caggtgacgt tctcccagca gaggatgcaa aacatggatg gaaatataca
181 ctggggtctc agtgtcctca tcagtaaatt tcagggtctg tgtggccaga tctgcagtct
241 cgaagccatg acagtcctga tgtgtgactg gtgggttgat aaaggaacat gttgtggaca
301 tggtggccct gctccacagt cacagtgtgg cctgggacat tcgtctgcaa gtctattgca
361 tcagcaacag gaaagactgg cttttctcag aaccagggct ggggtgggat gggggaagtt
421 gggaatgggg caagatagaa agacctgcca atttcctggg tccgctctgg gtcaggtctt
481 cataccgaac ctataacagc catacagttc tctgaacaat agagactcct atcgcagcca
541 gcataaatgg aaagagccca ggcctcttgg tgtgactgag gcctctgggt aagagtctgt
601 cacctcatca atgagcagtt cttagactct tgatgtctcc atatccagat tttttttcag
661 tttgaaattt ttctcccgtt agcccagttt ccagatagga gactgaggcc tacagaggtg
721 tcaggtgtgg aggtagaggt ccctttaagg acttcttggg tggttggtag cacttgatcc
781 ttcttagagg atacaccaca gaagctgagt gcatccgctg tcttcttcac gacggtaaca
841 cccatttgga gtcaggctag gtatggcctg tgaagctgcc agggttggtg ttctaaaact
901 ttgaatgctg ctggtctgca gcccacacta ctgactctag cttatcacct cattttattt
961 tctccctaat gtacatcaca acgtggacag tgggatagtg cagccagatt tcatgtgttc
1021 atcatgacct cttccccgtc cctaccccat gccagatctc aactgcctag catgctctta
1081 ggacacaatg ccgacacaca ggaggctctc tgtgcacgga tttctcttgg gctgagcgac
1141 tatgtgggct aagggactga aggcagaaac aggacaaacc gtggacacag ggcccctgcc
1201 ttgggatgtg agtgatgtgt aagtggaggt caaactcagg gcttcgtacc atgctaggca
1261 acccctctgc tacagcctca gcttggctgc ttcagaccct ggacctcacc agtcagaact
1321 gaagcaaaac tgtcaaggaa aatagcacag gagatggggg tgtacggttc agtggtgggg
1381 tgcatgtcct tacaaggctc tgagtttggc tcagccctga cgtagcggag gatagaagat
1441 ggggggagag agggagggtg ggaacaagcg ggcaggagag atttctagca gcctgtcaga
1501 gacatctcag gcccctagac actaagtgac atatgttcat atagatagtg tttttaaact
1561 ggaaagactg tccctacctt ggtttgtagc cacctgggct gagggccagc tgaggttact
1621 tggggcctgg cagcctgggt accacttgct catcttaccc ttggatcaca ttcacatgat
1681 gttctggcca ggcccttgac cccagttcct ctggggccaa ttcaatttgt ccagcctagg
1741 gcattctggg tgaggttatt ccaaaagatg tgtcagccac cctccgtttc tccacagggt
1801 tgtagtcatg gaaagactag agaaagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
1861 tgtgtgtgtg tgtatgcgtg tatgtgtgta ttagtgtgtg agtgtgttag cgtgtgtgta
1921 tatgtgttag tgtgtgtatg tgtatgttag tgtgtgtata tgtgagagta tgtgtgtatg
1981 tgtgtgtcag tgtgtgtgtg tgtgtgcgtg tgtgtgcgtg cgtgcataca aaggtcaaag
2041 gtcagcctct catgtcattc ctcaggagcc atcccctccc cctgtttgat atggagactc
2101 tctctctctg agacctgggg aatcaattga attaactagg ctggccaacc tgatagctcc
2161 agggaccctc ctgtctccta ggatcacaag ctgagactac cacaaagctt gcactctggg
2221 gagcaaactc aggtccacat gcagcatgta gcaacaccag taccaacgag atatcccccc
2281 agctgaatcc accttccgat gtgacataaa tgctggtccc agtctatcag ggttctctgt
2341 ctgccatgga gaccggaggg catcctggtc aggagtctgc tggctgggac ctgtccgtgc
2401 aaacacctct cagttcaaac acctatggct cccatatggt cggtacactg ggcagtgtgc
2461 tcacctttaa tcccaccact caggatggca gaggtcaagt agatctctgt gttcaagacc
2521 agcctggtct ccagaggtca agttatagga cagccagagc tatactcggt tcaaaaaacc
2581 aaaccaaaca aaaactccaa caacaacagc aacagcagca gcagcaacaa gaagcctgta
2641 agccaggagg gccaggtact tggggagccc cagcccttgg atctaaggta cagaggcctt
2701 aacaaaaggt agccctcgag tttctaactg cagcagaaga ggcccaggaa gggctggcca
2761 ctgggtcaga ggcagctgtt gcagggctcc aggggcccgt gtggctcttt tccatgcctc
2821 actggagtca gctctcccag ccctgaccgc aagggaacac tctgtttgcc agttctcacg
2881 tggtggccct gtgcttgggc actaaggcac agagtaatgc cctgaggggc ccgagtgtgg
2941 actcaaaggg agttacacaa ccagggctgg agaggactcc tttggagatt tccaaacctt
3001 gccgtttgtg agtggcaccc gtgtcctgcc gcatggcctt cgactggaca tactgctcag
3061 catgaacact ggaagaattt ctctccagaa gatgtaaaag tcatgatata ggctagaagg
3121 gaatcaacaa acatttattt aaagaggcac tttctgctct cacagaggac cctgggatct
3181 gttatccaca cctcacatgg tgtcttgaca tatgtaaatt cccttgcccc ttgccggatc
3241 gctgcaggcc ccaggcacac aacaggtgga gcacagacat atacaaaggc aaaacactca
3301 cacatataaa taaaatattt cacttcctaa tcaacctaga aacctcgttt acttcattct
3361 atttgtttgt ttttgtttgt ttattgtgac aagatcaaat acagagcccc ccacatggct
3421 gtgaatccca ccactgagct atagcttcca accccttaat tgattttggt tttagttttg
3481 gttttctctg agacaagatt tttcctttgt aacctaggct ggtctggaac tcattatgaa
3541 ggccagactg gcctccaatg atggtaatcc cactgcttca gcctcctgtg ggtgttggca
3601 tcacagtgag gagattcttt aatttaacat atcaattttg aagagtcaat tttgaatgtt
3661 cttttccaaa tcaatctagg gaaccatccg atgccaggtc tttgctggct gctacaggtt
3721 atcctgggct aatgtgtcct gccaactatt ctgttcacag accctgcttg atggaaaagt
3781 actcctgtaa agagaactgc tgggacttga acatgacaat gtcattgtga ctggacttct
3841 ggccctggct tcgaaatgct ttgtcctgta cagagcctgt tccagttcag gttactgctt
3901 cctctgttcg tttcacagct aggtacccag gccgagagag tgcagctgtg tgagttagga
3961 ggcaaggaag caggcagcaa aacggtaact tgacttcagg taacctaaaa gagctattga
4021 attgcctgca gtcaagtgta ctgggtgcca aggggacaca gcttccttct aactggttga
4081 gcagctgcta agaagagttg gccgcccact gaggcagtca tgcagacctg aagtgacaag
4141 cagaagcctg gccaggtttg tccctgggta gatggatcgc ctgatacgga cactggcgac
4201 caaacgctgg gattggctca aaacaaggcc gtgttgatcc agtgactggg ttttggcgtc
4261 ctgtcaatct gctgtctgct caaaagccta gaaatagtgc gggggcagtt tgctggtctc
4321 tgagaaagga agcagccatg caagtgctaa cgaaacgcta ccccaagaat tgcctgctga
4381 aggtcatgga tcggtactcg gctgtggtgc ggaacatgga gcaagtggtg atgatcccca
4441 gccttctgag ggatgtggag ctgatggggt acggaggctc ggtccaggac ggagcccccg
4501 atctctatac ctacttcacc atgctcaaga gcatctgtgt agaagtagac cacgggctgc
4561 tgccgcggga ggaatggcag gccaaggtgg caggcaatga aggcagtgag gctgagaatg
4621 aggctgctga aacagaggag gctgaggaag acaggctttc ggaggagctg gacctagaag
4681 cccagttcca cctgcacttc tccagcctcc atcacatcct tacccacctg acccagaaag
4741 cacaggaggt gacgcagaaa taccaggaaa tgacggggca ggtcctgtag gtcttcgact
4801 ctatggaag
//