GenBank-Updates@genbank.bio.net (05/03/91)
LOCUS HUMKRAS 113 bp ds-DNA PRI 03-MAY-1991
DEFINITION Human K-ras oncogene, 5' end.
ACCESSION M26261
KEYWORDS K-ras oncogene.
SOURCE Human lung giant cel carcinoma (LGCC) cell line Lu-65 DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 113)
AUTHORS Taya,Y., Hosogai,K., Hirohashi,S., Shimosato,Y., Tsuchiya,R.,
Tsuchida,N., Fushimi,M., Sekiya,T. and Nishimura,S.
TITLE A novel combination of K-ras and myc amplification accompanied by
point mutational activation of K-ras in a human lung cancer
JOURNAL EMBO J. 3, 2943-2946 (1984)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 14..113
/product="K-ras protein"
/gene="K-ras"
/codon_start=14
/partial
mutation 47..47
/note="t in Lu-65 cell line; g in wt (Cys in Lu-65; Gly in
wt)"
/gene="K-ras"
BASE COUNT 33 a 17 c 31 g 32 t
ORIGIN
1 aggcctgctg aaaatgactg aatataaact tgtggtagtt ggagcttgtg gcgtaggcaa
61 gagtgccttg acgatacagc taattcagaa tcattttgtg gacgaatatg atc
//