GenBank-Updates@genbank.bio.net (03/22/91)
LOCUS HUMGPAB 2050 bp ds-DNA PRI 22-MAR-1991
DEFINITION Human glycophorin A (HGpA) gene, exons 2-4.
ACCESSION M60707
KEYWORDS glycophorin A.
SOURCE Human fetal liver DNA, clone lambda-HGp4-2.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2050)
AUTHORS Huang,C.-H. and Blumenfeld,O.O.
TITLE Molecular genetics of human erythrocyte MiIII and MiVI
glycoporins...
JOURNAL Blood (1991) In press
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS join(38..136,844..939,1872..1910)
/number=3
/product="glycophorin A"
/gene="HGpA (alpha N)"
/codon_start=40
/partial
intron 1..37
/number=1
/gene="HGpA (alpha N)"
/partial
exon 38..136
/number=2
/gene="HGpA (alpha N)"
intron 137..843
/number=2
/gene="HGpA (alpha N)"
exon 844..939
/number=3
/gene="HGpA (alpha N)"
intron 940..1871
/number=3
/gene="HGpA (alpha N)"
exon 1872..1910
/number=3
/gene="HGpA (alpha N)"
intron 1911..2050
/number=4
/gene="HGpA (alpha N)"
/partial
BASE COUNT 656 a 399 c 393 g 602 t
ORIGIN
1 cgttcttaat ccctttctca acttctatgt tatacagcaa ttgtgagcat atcagcatta
61 agtaccactg aggtggcaat gcacacttca acctcttctt cagtcacaaa gagttacatc
121 tcatcacaga caaatggttt gttttcattt ttatttttaa attgtggctc cgaaatcatt
181 tttgtgatgt aaccctattt taggggacct gtcactgcag agaaactgac aaacactgag
241 aaatgcgagc taagtagaca cagcctacta agtagacaca attcctacta tggaggaatt
301 cttgcctctg aaatatctca cagaaataat actgtgagtt aaagaaatta aaacaatgtg
361 gcaaagacag aaatgatgca cgtgaccatg aaatagtggg ccagataaag gggacctaat
421 agtgcggtgg tgcagagggt ctgtgggcaa aatgagttca gctcagaccc gggctcagct
481 ctatgccagc tgctgaccca gggtgagttg ccctgcaggg tttctatccc attaatttta
541 aaatggggcc aataacacag tacttatctc acagcatttc tctaaaggct aaataagaag
601 atgtatctaa aagttattag ctcagagcct cacacattct cagtgactga taaacaataa
661 caaagctggg tgctgagata agagtaatct ggtggcagtc tctctcgtta gttttcaggg
721 gagaagaaga aattctggag ccgctgctgg gagggatgtg ggagagtttg tctttcataa
781 tacgctctat gtccacgcag tcacctcatt cttgacccct ttctcaactt ctcttatatg
841 cagatacgca caaacgggac acatatgcag ccactcctag agctcatgaa gtttcagaaa
901 tttctgttag aactgtttac cctccagaag aggaaaccgg tatgttctta gttttaaata
961 gttgctctgg agtcattgtt gtgattgaac tctatttaca cgagctgtaa ctcatgacag
1021 ttctcaagct ttcgtgacag aaaacccatc tcttttactc caaagcccat atagcaccca
1081 caactattaa ctgtgaccaa gaaagagaag gcaagcccca attaaccttt gtacgtaaag
1141 cctaaagaat gaaaaaatat acctgaatcc tcaatcatca aacagcatag tatatactaa
1201 gtaatttgta ataattaaac tctagaaaat tgtgtggctt tggtagtaag agagcttcat
1261 gacataaaat gcaagtggag acagagacaa aagtaggatg tggactgaga gggaaggtta
1321 gcacaggtgg aacagtaagg caaccatact atcaattgct actgacatag aatccagaga
1381 gactattggc aaaagctcaa atgagacaca gtaacagttt agattcagac agtggctgtg
1441 gcataaatca gaaaattgat agccgcatga tccctctttg catgggactg gcatctgtgt
1501 ggagtaatgg ttccatatgc ctcctttctt ctccttattt ttaaattttt taaaaataca
1561 ttgcttcttg tggaagtcaa taagtgattc ttccaatact ttctcattcc ttccccctca
1621 gttatgagac aatttgctta tttctcatcc atgaatactt gttgggtcat taaaagtaga
1681 tactgaaatt actaatggta cgactgacat attacctcat aaatgttact agctagatgt
1741 tgaaagttga ccaacaactc tcaaaatatg attaagaaaa ggaaacccac agaacagttt
1801 gattccaaaa tgattttttt ctttgcacat gccttactta tttggactta cattgaaatt
1861 ttgctttata ggagaaaggg tacaacttgc ccatcatttc tctgaaccag gtatgttaat
1921 atttgacaaa gaataaaagt cattccattt taaactatcc attgcttgtt tcaaatgcct
1981 aagaaaatgt gtctatctta gaagagcata tgttgttaac ttttattcac acaaaattgt
2041 aaaggcaaag
//GenBank-Updates@genbank.bio.net (05/04/91)
LOCUS HUMGPAB 2050 bp ds-DNA PRI 04-MAY-1991
DEFINITION Human glycophorin A (HGpA) gene, exons 2-4.
ACCESSION M60707
KEYWORDS glycophorin A.
SOURCE Human fetal liver DNA, clone lambda-HGp4-2.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2050)
AUTHORS Huang,C.-H. and Blumenfeld,O.O.
TITLE Identification of recombination events resulting in three hybrid
genes.....
JOURNAL Blood (1991) In press
STANDARD simple staff_entry
REFERENCE 2 (sites)
AUTHORS Huang,C.-H. and Blumenfeld,O.O.
TITLE Molecular genetics of human erythrocyte MiIII and MiVI
glycophorins: Use of a pseudoexon in construction of two
delta-alpha-delta hybrid genes resulting in antigenic
diversification
JOURNAL J. Biol. Chem. 266, 7248-7255 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS join(38..136,844..939,1872..1910)
/number=3
/product="glycophorin A"
/gene="HGpA (alpha N)"
/codon_start=40
/partial
intron 1..37
/number=1
/gene="HGpA (alpha N)"
/partial
exon 38..136
/number=2
/gene="HGpA (alpha N)"
intron 137..843
/number=2
/gene="HGpA (alpha N)"
exon 844..939
/number=3
/gene="HGpA (alpha N)"
intron 940..1871
/number=3
/gene="HGpA (alpha N)"
exon 1872..1910
/number=3
/gene="HGpA (alpha N)"
intron 1911..2050
/number=4
/gene="HGpA (alpha N)"
/partial
BASE COUNT 656 a 399 c 393 g 602 t
ORIGIN
1 cgttcttaat ccctttctca acttctatgt tatacagcaa ttgtgagcat atcagcatta
61 agtaccactg aggtggcaat gcacacttca acctcttctt cagtcacaaa gagttacatc
121 tcatcacaga caaatggttt gttttcattt ttatttttaa attgtggctc cgaaatcatt
181 tttgtgatgt aaccctattt taggggacct gtcactgcag agaaactgac aaacactgag
241 aaatgcgagc taagtagaca cagcctacta agtagacaca attcctacta tggaggaatt
301 cttgcctctg aaatatctca cagaaataat actgtgagtt aaagaaatta aaacaatgtg
361 gcaaagacag aaatgatgca cgtgaccatg aaatagtggg ccagataaag gggacctaat
421 agtgcggtgg tgcagagggt ctgtgggcaa aatgagttca gctcagaccc gggctcagct
481 ctatgccagc tgctgaccca gggtgagttg ccctgcaggg tttctatccc attaatttta
541 aaatggggcc aataacacag tacttatctc acagcatttc tctaaaggct aaataagaag
601 atgtatctaa aagttattag ctcagagcct cacacattct cagtgactga taaacaataa
661 caaagctggg tgctgagata agagtaatct ggtggcagtc tctctcgtta gttttcaggg
721 gagaagaaga aattctggag ccgctgctgg gagggatgtg ggagagtttg tctttcataa
781 tacgctctat gtccacgcag tcacctcatt cttgacccct ttctcaactt ctcttatatg
841 cagatacgca caaacgggac acatatgcag ccactcctag agctcatgaa gtttcagaaa
901 tttctgttag aactgtttac cctccagaag aggaaaccgg tatgttctta gttttaaata
961 gttgctctgg agtcattgtt gtgattgaac tctatttaca cgagctgtaa ctcatgacag
1021 ttctcaagct ttcgtgacag aaaacccatc tcttttactc caaagcccat atagcaccca
1081 caactattaa ctgtgaccaa gaaagagaag gcaagcccca attaaccttt gtacgtaaag
1141 cctaaagaat gaaaaaatat acctgaatcc tcaatcatca aacagcatag tatatactaa
1201 gtaatttgta ataattaaac tctagaaaat tgtgtggctt tggtagtaag agagcttcat
1261 gacataaaat gcaagtggag acagagacaa aagtaggatg tggactgaga gggaaggtta
1321 gcacaggtgg aacagtaagg caaccatact atcaattgct actgacatag aatccagaga
1381 gactattggc aaaagctcaa atgagacaca gtaacagttt agattcagac agtggctgtg
1441 gcataaatca gaaaattgat agccgcatga tccctctttg catgggactg gcatctgtgt
1501 ggagtaatgg ttccatatgc ctcctttctt ctccttattt ttaaattttt taaaaataca
1561 ttgcttcttg tggaagtcaa taagtgattc ttccaatact ttctcattcc ttccccctca
1621 gttatgagac aatttgctta tttctcatcc atgaatactt gttgggtcat taaaagtaga
1681 tactgaaatt actaatggta cgactgacat attacctcat aaatgttact agctagatgt
1741 tgaaagttga ccaacaactc tcaaaatatg attaagaaaa ggaaacccac agaacagttt
1801 gattccaaaa tgattttttt ctttgcacat gccttactta tttggactta cattgaaatt
1861 ttgctttata ggagaaaggg tacaacttgc ccatcatttc tctgaaccag gtatgttaat
1921 atttgacaaa gaataaaagt cattccattt taaactatcc attgcttgtt tcaaatgcct
1981 aagaaaatgt gtctatctta gaagagcata tgttgttaac ttttattcac acaaaattgt
2041 aaaggcaaag
//