GenBank-Updates@genbank.bio.net (03/15/91)
LOCUS HUMTYR01 1629 bp ds-DNA PRI 15-MAR-1991 DEFINITION Human tyrosinase gene, exon 1. ACCESSION M63235 M60296 KEYWORDS tyrosinase. SOURCE Human DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (sites) AUTHORS Giebel,L.B., Strunk,K.M. and Spritz,R.A. TITLE Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosine-related segment JOURNAL Genomics (1991) In press STANDARD full staff_review FEATURES Location/Qualifiers exon 590..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 595..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 624..1488 /number=1 /note="major 5' mRNA terminus" /evidence=EXPERIMENTAL sig_peptide 670..723 /codon_start=670 BASE COUNT 469 a 342 c 353 g 465 t ORIGIN 1 gttatcaaag tgagctatcc ttaggagttg tcagaaaatg catcaggatt atcagagaaa 61 agtatcagaa agattttttt tttctgatac gttgtataaa ataaacaaac tgaaattcaa 121 taacatataa ggaattctgt ctgggctgaa gacaatctct ctctgcatat tgagttcttc 181 aaacattgta gcctctttat ggtctctgag aaataactac cttaaaccca taatctttaa 241 tacttcctaa actttcttaa taagagaagc tctattcctg acactacctc tcatttgcaa 301 ggtcaaatca tcattagttt tgtagtctat taactgggtt tgcttaggtc aggcattatt 361 attactaacc ttattgttaa tattctaacc ataagaatta aactattaat ggtgaataga 421 gtttttcact ttaacatagg cctatcccac tggtgggata cgagccaatt cgaaagaaaa 481 gtcagtcatg tgcttttcag aggatgaaag cttaagataa agactaaaag tgtttgatgc 541 tggaggtggg agtggtatta tataggtctc agccaagaca tgtgataatc actgtagtag 601 tagctggaaa gagaaatctg tgactccaat tagccagttc ctgcagacct tgtgaggact 661 agaggaagaa tgctcctggc tgttttgtac tgcctgctgt ggagtttcca gacctccgct 721 ggccatttcc ctagagcctg tgtctcctct aagaacctga tggagaagga atgctgtcca 781 ccgtggagcg gggacaggag tccctgtggc cagctttcag gcagaggttc ctgtcagaat 841 atccttctgt ccaatgcacc acttgggcct caatttccct tcacaggggt ggatgaccgg 901 gagtcgtggc cttccgtctt ttataatagg acctgccagt gctctggcaa cttcatggga 961 ttcaactgtg gaaactgcaa gtttggcttt tggggaccaa actgcacaga gagacgactc 1021 ttggtgagaa gaaacatctt cgatttgagt gccccagaga aggacaaatt ttttgcctac 1081 ctcactttag caaagcatac catcagctca gactatgtca tccccatagg gacctatggc 1141 caaatgaaaa atggatcaac acccatgttt aacgacatca atatttatga cctctttgtc 1201 tggatgcatt attatgtgtc aatggatgca ctgcttgggg gatctgaaat ctggagagac 1261 attgattttg cccatgaagc accagctttt ctgccttggc atagactctt cttgttgcgg 1321 tgggaacaag aaatccagaa gctgacagga gatgaaaact tcactattcc atattgggac 1381 tggcgggatg cagaaaagtg tgacatttgc acagatgagt acatgggagg tcagcacccc 1441 acaaatccta acttactcag cccagcatca ttcttctcct cttggcaggt aagatatact 1501 agatatacga tgtcagagta gggaggaacc ttaacaatca cttcttcagg cagggtataa 1561 acttctcacc tgaacactca ttgcagcccc catcaaggac agaaatggtg ccctgttaag 1621 aactctcaa //
GenBank-Updates@genbank.bio.net (03/27/91)
LOCUS HUMTYR01 1629 bp ds-DNA PRI 27-MAR-1991 DEFINITION Human tyrosinase gene, exon 1. ACCESSION M63235 M60296 KEYWORDS tyrosinase. SOURCE Human DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (sites) AUTHORS Giebel,L.B., Strunk,K.M. and Spritz,R.A. TITLE Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosine-related segment JOURNAL Genomics (1991) In press STANDARD full staff_review FEATURES Location/Qualifiers exon 590..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 595..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 624..1488 /number=1 /note="major 5' mRNA terminus" /evidence=EXPERIMENTAL sig_peptide 670..723 /codon_start=670 BASE COUNT 469 a 342 c 353 g 465 t ORIGIN 1 gttatcaaag tgagctatcc ttaggagttg tcagaaaatg catcaggatt atcagagaaa 61 agtatcagaa agattttttt tttctgatac gttgtataaa ataaacaaac tgaaattcaa 121 taacatataa ggaattctgt ctgggctgaa gacaatctct ctctgcatat tgagttcttc 181 aaacattgta gcctctttat ggtctctgag aaataactac cttaaaccca taatctttaa 241 tacttcctaa actttcttaa taagagaagc tctattcctg acactacctc tcatttgcaa 301 ggtcaaatca tcattagttt tgtagtctat taactgggtt tgcttaggtc aggcattatt 361 attactaacc ttattgttaa tattctaacc ataagaatta aactattaat ggtgaataga 421 gtttttcact ttaacatagg cctatcccac tggtgggata cgagccaatt cgaaagaaaa 481 gtcagtcatg tgcttttcag aggatgaaag cttaagataa agactaaaag tgtttgatgc 541 tggaggtggg agtggtatta tataggtctc agccaagaca tgtgataatc actgtagtag 601 tagctggaaa gagaaatctg tgactccaat tagccagttc ctgcagacct tgtgaggact 661 agaggaagaa tgctcctggc tgttttgtac tgcctgctgt ggagtttcca gacctccgct 721 ggccatttcc ctagagcctg tgtctcctct aagaacctga tggagaagga atgctgtcca 781 ccgtggagcg gggacaggag tccctgtggc cagctttcag gcagaggttc ctgtcagaat 841 atccttctgt ccaatgcacc acttgggcct caatttccct tcacaggggt ggatgaccgg 901 gagtcgtggc cttccgtctt ttataatagg acctgccagt gctctggcaa cttcatggga 961 ttcaactgtg gaaactgcaa gtttggcttt tggggaccaa actgcacaga gagacgactc 1021 ttggtgagaa gaaacatctt cgatttgagt gccccagaga aggacaaatt ttttgcctac 1081 ctcactttag caaagcatac catcagctca gactatgtca tccccatagg gacctatggc 1141 caaatgaaaa atggatcaac acccatgttt aacgacatca atatttatga cctctttgtc 1201 tggatgcatt attatgtgtc aatggatgca ctgcttgggg gatctgaaat ctggagagac 1261 attgattttg cccatgaagc accagctttt ctgccttggc atagactctt cttgttgcgg 1321 tgggaacaag aaatccagaa gctgacagga gatgaaaact tcactattcc atattgggac 1381 tggcgggatg cagaaaagtg tgacatttgc acagatgagt acatgggagg tcagcacccc 1441 acaaatccta acttactcag cccagcatca ttcttctcct cttggcaggt aagatatact 1501 agatatacga tgtcagagta gggaggaacc ttaacaatca cttcttcagg cagggtataa 1561 acttctcacc tgaacactca ttgcagcccc catcaaggac agaaatggtg ccctgttaag 1621 aactctcaa //
GenBank-Updates@genbank.bio.net (03/28/91)
LOCUS HUMTYR01 1629 bp ds-DNA PRI 28-MAR-1991 DEFINITION Human tyrosinase gene, exon 1. ACCESSION M63235 M60296 KEYWORDS tyrosinase. SOURCE Human DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (sites) AUTHORS Giebel,L.B., Strunk,K.M. and Spritz,R.A. TITLE Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosine-related segment JOURNAL Genomics (1991) In press STANDARD full staff_review FEATURES Location/Qualifiers exon 590..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 595..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 624..1488 /number=1 /note="major 5' mRNA terminus" /evidence=EXPERIMENTAL sig_peptide 670..723 /codon_start=670 BASE COUNT 469 a 342 c 353 g 465 t ORIGIN 1 gttatcaaag tgagctatcc ttaggagttg tcagaaaatg catcaggatt atcagagaaa 61 agtatcagaa agattttttt tttctgatac gttgtataaa ataaacaaac tgaaattcaa 121 taacatataa ggaattctgt ctgggctgaa gacaatctct ctctgcatat tgagttcttc 181 aaacattgta gcctctttat ggtctctgag aaataactac cttaaaccca taatctttaa 241 tacttcctaa actttcttaa taagagaagc tctattcctg acactacctc tcatttgcaa 301 ggtcaaatca tcattagttt tgtagtctat taactgggtt tgcttaggtc aggcattatt 361 attactaacc ttattgttaa tattctaacc ataagaatta aactattaat ggtgaataga 421 gtttttcact ttaacatagg cctatcccac tggtgggata cgagccaatt cgaaagaaaa 481 gtcagtcatg tgcttttcag aggatgaaag cttaagataa agactaaaag tgtttgatgc 541 tggaggtggg agtggtatta tataggtctc agccaagaca tgtgataatc actgtagtag 601 tagctggaaa gagaaatctg tgactccaat tagccagttc ctgcagacct tgtgaggact 661 agaggaagaa tgctcctggc tgttttgtac tgcctgctgt ggagtttcca gacctccgct 721 ggccatttcc ctagagcctg tgtctcctct aagaacctga tggagaagga atgctgtcca 781 ccgtggagcg gggacaggag tccctgtggc cagctttcag gcagaggttc ctgtcagaat 841 atccttctgt ccaatgcacc acttgggcct caatttccct tcacaggggt ggatgaccgg 901 gagtcgtggc cttccgtctt ttataatagg acctgccagt gctctggcaa cttcatggga 961 ttcaactgtg gaaactgcaa gtttggcttt tggggaccaa actgcacaga gagacgactc 1021 ttggtgagaa gaaacatctt cgatttgagt gccccagaga aggacaaatt ttttgcctac 1081 ctcactttag caaagcatac catcagctca gactatgtca tccccatagg gacctatggc 1141 caaatgaaaa atggatcaac acccatgttt aacgacatca atatttatga cctctttgtc 1201 tggatgcatt attatgtgtc aatggatgca ctgcttgggg gatctgaaat ctggagagac 1261 attgattttg cccatgaagc accagctttt ctgccttggc atagactctt cttgttgcgg 1321 tgggaacaag aaatccagaa gctgacagga gatgaaaact tcactattcc atattgggac 1381 tggcgggatg cagaaaagtg tgacatttgc acagatgagt acatgggagg tcagcacccc 1441 acaaatccta acttactcag cccagcatca ttcttctcct cttggcaggt aagatatact 1501 agatatacga tgtcagagta gggaggaacc ttaacaatca cttcttcagg cagggtataa 1561 acttctcacc tgaacactca ttgcagcccc catcaaggac agaaatggtg ccctgttaag 1621 aactctcaa //
GenBank-Updates@genbank.bio.net (04/03/91)
LOCUS HUMTYR01 1629 bp ds-DNA PRI 03-APR-1991 DEFINITION Human tyrosinase gene, exon 1. ACCESSION M63235 M60296 KEYWORDS tyrosinase. SEGMENT 1 of 5 SOURCE Human DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (sites) AUTHORS Giebel,L.B., Strunk,K.M. and Spritz,R.A. TITLE Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosine-related segment JOURNAL Genomics (1991) In press STANDARD full staff_review FEATURES Location/Qualifiers exon 590..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 595..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 624..1488 /number=1 /note="major 5' mRNA terminus" /evidence=EXPERIMENTAL sig_peptide 670..723 /codon_start=670 BASE COUNT 469 a 342 c 353 g 465 t ORIGIN 1 gttatcaaag tgagctatcc ttaggagttg tcagaaaatg catcaggatt atcagagaaa 61 agtatcagaa agattttttt tttctgatac gttgtataaa ataaacaaac tgaaattcaa 121 taacatataa ggaattctgt ctgggctgaa gacaatctct ctctgcatat tgagttcttc 181 aaacattgta gcctctttat ggtctctgag aaataactac cttaaaccca taatctttaa 241 tacttcctaa actttcttaa taagagaagc tctattcctg acactacctc tcatttgcaa 301 ggtcaaatca tcattagttt tgtagtctat taactgggtt tgcttaggtc aggcattatt 361 attactaacc ttattgttaa tattctaacc ataagaatta aactattaat ggtgaataga 421 gtttttcact ttaacatagg cctatcccac tggtgggata cgagccaatt cgaaagaaaa 481 gtcagtcatg tgcttttcag aggatgaaag cttaagataa agactaaaag tgtttgatgc 541 tggaggtggg agtggtatta tataggtctc agccaagaca tgtgataatc actgtagtag 601 tagctggaaa gagaaatctg tgactccaat tagccagttc ctgcagacct tgtgaggact 661 agaggaagaa tgctcctggc tgttttgtac tgcctgctgt ggagtttcca gacctccgct 721 ggccatttcc ctagagcctg tgtctcctct aagaacctga tggagaagga atgctgtcca 781 ccgtggagcg gggacaggag tccctgtggc cagctttcag gcagaggttc ctgtcagaat 841 atccttctgt ccaatgcacc acttgggcct caatttccct tcacaggggt ggatgaccgg 901 gagtcgtggc cttccgtctt ttataatagg acctgccagt gctctggcaa cttcatggga 961 ttcaactgtg gaaactgcaa gtttggcttt tggggaccaa actgcacaga gagacgactc 1021 ttggtgagaa gaaacatctt cgatttgagt gccccagaga aggacaaatt ttttgcctac 1081 ctcactttag caaagcatac catcagctca gactatgtca tccccatagg gacctatggc 1141 caaatgaaaa atggatcaac acccatgttt aacgacatca atatttatga cctctttgtc 1201 tggatgcatt attatgtgtc aatggatgca ctgcttgggg gatctgaaat ctggagagac 1261 attgattttg cccatgaagc accagctttt ctgccttggc atagactctt cttgttgcgg 1321 tgggaacaag aaatccagaa gctgacagga gatgaaaact tcactattcc atattgggac 1381 tggcgggatg cagaaaagtg tgacatttgc acagatgagt acatgggagg tcagcacccc 1441 acaaatccta acttactcag cccagcatca ttcttctcct cttggcaggt aagatatact 1501 agatatacga tgtcagagta gggaggaacc ttaacaatca cttcttcagg cagggtataa 1561 acttctcacc tgaacactca ttgcagcccc catcaaggac agaaatggtg ccctgttaag 1621 aactctcaa //
GenBank-Updates@genbank.bio.net (05/04/91)
LOCUS HUMTYR01 1629 bp ds-DNA PRI 04-MAY-1991 DEFINITION Human tyrosinase gene, exon 1. ACCESSION M63235 M60296 KEYWORDS tyrosinase. SEGMENT 1 of 5 SOURCE Human DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (sites) AUTHORS Giebel,L.B., Strunk,K.M. and Spritz,R.A. TITLE Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosine-related segment JOURNAL Genomics 9, 435-445 (1991) STANDARD full staff_review FEATURES Location/Qualifiers exon 590..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 595..1488 /number=1 /note="minor 5' mRNA terminus" /evidence=EXPERIMENTAL exon 624..1488 /number=1 /note="major 5' mRNA terminus" /evidence=EXPERIMENTAL sig_peptide 670..723 /codon_start=670 BASE COUNT 469 a 342 c 353 g 465 t ORIGIN 1 gttatcaaag tgagctatcc ttaggagttg tcagaaaatg catcaggatt atcagagaaa 61 agtatcagaa agattttttt tttctgatac gttgtataaa ataaacaaac tgaaattcaa 121 taacatataa ggaattctgt ctgggctgaa gacaatctct ctctgcatat tgagttcttc 181 aaacattgta gcctctttat ggtctctgag aaataactac cttaaaccca taatctttaa 241 tacttcctaa actttcttaa taagagaagc tctattcctg acactacctc tcatttgcaa 301 ggtcaaatca tcattagttt tgtagtctat taactgggtt tgcttaggtc aggcattatt 361 attactaacc ttattgttaa tattctaacc ataagaatta aactattaat ggtgaataga 421 gtttttcact ttaacatagg cctatcccac tggtgggata cgagccaatt cgaaagaaaa 481 gtcagtcatg tgcttttcag aggatgaaag cttaagataa agactaaaag tgtttgatgc 541 tggaggtggg agtggtatta tataggtctc agccaagaca tgtgataatc actgtagtag 601 tagctggaaa gagaaatctg tgactccaat tagccagttc ctgcagacct tgtgaggact 661 agaggaagaa tgctcctggc tgttttgtac tgcctgctgt ggagtttcca gacctccgct 721 ggccatttcc ctagagcctg tgtctcctct aagaacctga tggagaagga atgctgtcca 781 ccgtggagcg gggacaggag tccctgtggc cagctttcag gcagaggttc ctgtcagaat 841 atccttctgt ccaatgcacc acttgggcct caatttccct tcacaggggt ggatgaccgg 901 gagtcgtggc cttccgtctt ttataatagg acctgccagt gctctggcaa cttcatggga 961 ttcaactgtg gaaactgcaa gtttggcttt tggggaccaa actgcacaga gagacgactc 1021 ttggtgagaa gaaacatctt cgatttgagt gccccagaga aggacaaatt ttttgcctac 1081 ctcactttag caaagcatac catcagctca gactatgtca tccccatagg gacctatggc 1141 caaatgaaaa atggatcaac acccatgttt aacgacatca atatttatga cctctttgtc 1201 tggatgcatt attatgtgtc aatggatgca ctgcttgggg gatctgaaat ctggagagac 1261 attgattttg cccatgaagc accagctttt ctgccttggc atagactctt cttgttgcgg 1321 tgggaacaag aaatccagaa gctgacagga gatgaaaact tcactattcc atattgggac 1381 tggcgggatg cagaaaagtg tgacatttgc acagatgagt acatgggagg tcagcacccc 1441 acaaatccta acttactcag cccagcatca ttcttctcct cttggcaggt aagatatact 1501 agatatacga tgtcagagta gggaggaacc ttaacaatca cttcttcagg cagggtataa 1561 acttctcacc tgaacactca ttgcagcccc catcaaggac agaaatggtg ccctgttaag 1621 aactctcaa //