GenBank-Updates@genbank.bio.net (04/09/91)
LOCUS DROTMLPA 5546 bp ss-mRNA INV 09-APR-1991
DEFINITION D.melanogaster serrate (Ser) mRNA, complete cds.
ACCESSION M35759
KEYWORDS Ser gene; serrate.
SOURCE D.melanogaster pupa, cDNA to mRNA.
ORGANISM Drosophila melanogaster
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (bases 1 to 5546)
AUTHORS Fleming,R.J., Scottgale,T.N., Diederich,R.J. and
Artavanis-Tsakonas,S.
TITLE The gene Serrate encodes a putative EGF-like transmembrane protein
essential for proper ectodermal development in Drosophila
melanogaster
JOURNAL Unpublished (1990)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by R.J.Fleming, 28-JUN-1990.
Author address: R.J.Fleming
Yale University
Dept of Biology
KBT 1104
New Haven, CT 06511
email: WHAKRIA@YALEVM
FEATURES Location/Qualifiers
mRNA <1..5546
/note="serrate protein"
CDS 443..4657
/note="serrate protein precursor"
/codon_start=443
sig_peptide 443..679
/note="serrate protein signal peptide"
/codon_start=443
mat_peptide 680..4657
/note="serrate protein"
/codon_start=680
BASE COUNT 1384 a 1446 c 1504 g 1212 t
ORIGIN Chromosome 3 97F.
1 ccgagtcgag cgccgtgctt cgagcggtga tgagcccctt ttctgtcaac gctaaagatc
61 tacaaaacat cagcgcctat caagtggaag tgtcaagtgt gaacaaaaca aaaacgagag
121 aagcacatac taaggtccat ataaataata aataataatt gtgtgtgata acaacattat
181 ccaaacaaaa ccaaacaaaa cgaaggcaaa gtggagaaaa tgatacagca tccagagtac
241 ggccagttat tcagctatcc agagcaagtg tagtgtggca aaatagaaac aaacaaaggc
301 accaaaatct gcatacatgg gctaattaag gctgcccagc gaatttacat ttgtgtggtg
361 ccaatccaga gtgaatccga aacaaactcc atctagatcg ccaaccagca tcacgctcgc
421 aaacgccccc agaatgtaca aaatgtttag gaaacatttt cggcgaaaac cagctacgtc
481 gtcgtcgttg gagtcaacaa tagaatcagc agacagcctg ggaatgtcca agaagacggc
541 gacaaaaagg cagcgtccga ggcatcgggt acccaaaatc gcgaccctgc catcgacgat
601 ccgcgattgt cgatcattaa agtctgcctg caacttaatt gctttaattt taatactgtt
661 agtccataag atatccgcag ctggtaactt cgagctggaa atattagaaa tctcaaatac
721 caacagccat ctactcaacg gctattgctg cggcatgcca gcggaactta gggccaccaa
781 gacgataggc tgctcgccat gcacgacggc attccggctg tgcctgaagg agtaccagac
841 cacggagcag ggtgccagca tatccacggg ctgttcgttt ggcaacgcca ccaccaagat
901 actgggtggc tccagctttg tgctcagcga tccgggtgtg ggagccattg tgctgccctt
961 tacgtttcgt tggacgaagt cgtttacgct gatactgcag gcgttggata tgtacaacac
1021 atcctatcca gatgcggaga ggttaattga ggaaacatca tactcgggcg tgatactgcc
1081 gtcgccggag tggaagacgc tggaccacat cgggcggaac gcgcggatca cctaccgtgt
1141 ccgggtgcaa tgcgccgtta cctactacaa cacgacctgc acgaccttct gccgtccgcg
1201 ggacgatcag ttcggtcact acgcctgcgg ctccgagggt cagaagctct gcctgaatgg
1261 ctggcagggc gtcaactgcg aggaggccat atgcaaggcg ggctgcgacc ccgtccacgg
1321 caagtgcgat cgtccggggg aatgcgaatg cagacccggc tggcgtggtc cattgtgcaa
1381 cgagtgcatg gtctatcccg gctgcaagca tggttcctgc aacggcagcg cctggaaatg
1441 cgtgtgcgac accaactggg gtggcatatt gtgcgatcaa gatttaaatt tctgcggcac
1501 ccatgaaccc tgcaagcacg gcggcacctg cgaaaatacc gctccggaca aatatcggtg
1561 cacatgcgcc gagggcctct cgggcgagca gtgcgagatc gtggagcacc catgtgccac
1621 caggccatgc cgcaacggcg gcacatgcac actcaagacg agtaaccgaa ctcaagccca
1681 agtgtatcgc acatcacatg gcaggagcaa catgggccgg ccggtaagac gcagcagttc
1741 gatgcgcagc ctggatcacc tgcggccgga ggggcaggcg ctgaatggca gcagctcctc
1801 gggattggtg tccctaggtt cgctgcagct gcagcagcaa ctggcccccg acttcacttg
1861 cgactgcgca gccggatgga cgggaccgac atgcgaaata aatatcgacg agtgcgccgg
1921 gggtccctgc gagcatggtg gcacttgcat cgatctaatc ggtggctttc gatgtgaatg
1981 tccgccggag tggcatggcg atgtctgtca ggtggatgtg aacgagtgcg aggcgccgca
2041 ttccgccgga atcgctgcga acgcattgct gaccaccaca gccaccgcga ttattggtag
2101 taatctgagc agtactgctc ttctggccgc tctgaccagt gcagtggcat ccacatcctt
2161 ggccatcgga ccctgcatca atgccaagga gtgtcgcaat cagccgggtt cctttgcctg
2221 catctgcaag gagggctggg gcggagtgac ctgtgccgag aatctagatg actgtgtggg
2281 tcagtgccgg aatggagcca cctgcattga tctggtcaac gactataggt gcgcctgtgc
2341 ctctggattc acgggtcgcg attgcgagac ggacatagac gagtgcgcca cttccccgtg
2401 ccgaaacgga ggcgaatgtg tggacatggt gggcaaattc aattgcattt gcccacttgg
2461 ctactcgggt tctctgtgcg aggaggccaa ggagaactgc acaccgtcgc catgtttgga
2521 gggtcactgc ctcaacacgc ccgaaggata ctactgccat tgtccaccgg atcgcgccgg
2581 aaagcactgc gagcaactgc gtccgctctg ctcccagccg ccctgcaacg agggctgctt
2641 cgccaatgtc agcctagcga cgtcagcgac aacgacgacg acaaccacca caacggcgac
2701 aacgacaagg aagatggcca agccaagcgg attgccctgc agcggacacg gcagctgcga
2761 gatgagcgac gtgggcacct tctgcaaatg ccatgtgggc cacaccggca ccttctgcga
2821 gcacaatctc aacgaatgct cgccgaatcc ttgtcgaaat gggggaattt gccttgacgg
2881 cgacggcgat tttacatgcg agtgcatgtc gggctggaca ggtaaacgct gctcggagcg
2941 cgctacaggt tgttatgccg gtcagtgcca gaatggtggt acctgcatgc ctggagcccc
3001 ggacaaggct ctgcagccgc attgccgctg tgcgccaggt tggactggtc tgttttgcgc
3061 cgaggctatt gaccagtgtc gcgggcagcc gtgccacaat ggcggaacgt gcgagtcggg
3121 agcgggctgg ttccgctgcg tctgcgctca gggattctct ggtccagact gccgcatcaa
3181 tgtgaacgag tgctcgccac agccttgcca gggcggtgcc acctgcatcg acggaatcgg
3241 tggatacagc tgcatctgcc caccaggaag gcatggattg cggtgtgaaa ttttgctctc
3301 cgatcccaag tccgcctgcc agaacgcaag caacactatc tctccgtata cagctctaaa
3361 ccgaagccaa aactggctgg atattgctct aaccggaaga acagaagacg atgagaactg
3421 caatgcgtgt gtctgcgaaa acggcacctc tcggtgcacg aatctctggt gtggattgcc
3481 caattgctat aaggtggatc cgctctccaa gtcctcgaat ctgtccggtg tttgcaaaca
3541 gcacgaggtg tgcgttccgg cactgagtga gacatgcctg tcatcgcctt gtaatgttcg
3601 tggagattgc cgggcactgg aaccatcgcg tcgggttgct ccaccccgac tgccagccaa
3661 atctagctgc tggcccaatc aggccgtggt caacgagaac tgcgcccgac tcaccatcct
3721 tttggccctg gagcgagtgg gcaagggagc ttcggtggag ggtctctgct ccctggtaag
3781 ggtgctgctg gctgcccagt tgatcaagaa gccggcgagt acttttggcc aggatccggg
3841 aatgcttatg gtgctctgcg atctcaaaac gggcaccaat gataccgttg aactaactgt
3901 gtcgtccagt aaattaaatg atccccagct gccagtggcg gtgggtctgc tgggtgaact
3961 cctgagctcc aggcagttga atggcatcca gcggcgcaag gaactggagc tgcagcatgc
4021 aaaattggct gccctcacct ccattgtgga ggtcaagttg gaaacggccc gcgtggccga
4081 tggatcgggt catagtctgc tgataggagt gctatgcggt gtctttatag tcctggtggg
4141 attctcggtg ttcatcagtc tttactggaa acagcgtctg gcttatcgca ccagttcggg
4201 aatgaactta actccctccc tggatgcact gcgtcacgag gaggagaagt cgaataatct
4261 gcagaacgag gagaatctgc gaaggtatac aaatccgctg aagggcagca ccagttccct
4321 aagagcggcc accggcatgg aactaagcct caatcccgct ccggaattag ccgcctcggc
4381 ggcgagtagt tccgccttgc acagatcgca gccactattc ccgccatgcg atttcgagcg
4441 tgagctggac tccagtacgg gcctgaagca ggcgcacaag cggagctcac agattctgct
4501 gcacaaaacc caaaactcgg acatgcggaa gaacactgtg ggctcgctgg acagtccgcg
4561 taaggacttt ggcaagcggt cgatcaactg caagtccatg ccaccctctt cgggcgacga
4621 gggctccgat gtccttgcca ccactgtgat ggtttagccg tgatctcacc aaccaaccaa
4681 tcaagaaacc aaccagccgc ccacagccag ctcaaagttc caattgccac agcacgggcg
4741 ctatttccaa gtgcattagt agcgtaatta aaactaggat attgttaagg ataccaaggt
4801 aggccacaac ggagtggctc tgttgaaaac gtaaagttct aaaaatccag gtctctcaga
4861 caaagatgag gtacacaaat aaattggcta gttaatcaag catgttatgg ccacgggatg
4921 ggcaaattta tttgtatacc tgatcttatc ttaatactaa accagttttc tactattttt
4981 tttttgtgga tcaagcttaa aagttcagct aggcaggcgt tttccgcagt gccatgtcga
5041 tgtggaagcc caaaatattt aggttagata gtgtaatttc gaactcttct cttcgctaag
5101 caacatccta cacagtgtga tatttagtgt aacccaggcg cgcatttaca ttcaattaaa
5161 gacaatgata tataaatata aacgaaatca actccttggc tagcacaagc tgtatgtata
5221 tagttctcat ttaggatcgt cgcgctctat attgtgtata agctgtaaat actgtaaatt
5281 agcagttacc gttattgtat tttgtctata gttagattgg tactattaaa ctaagaacca
5341 gccgcaacgc gttagacttt aaaagttgtt tgcaattgta cgcaataata tagttttatg
5401 ctcgtagtta ggtagctgtg taaccgggta agattcaaac gattttgtac tgtattatat
5461 acctatctgt gtagtaatat ttatttatta tattaaattt gatctagacg caataaagta
5521 atatcaataa agatagtaaa agacat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS DROTMLPA 5546 bp ss-mRNA INV 08-MAY-1991
DEFINITION D.melanogaster serrate (Ser) mRNA, complete cds.
ACCESSION M35759
KEYWORDS Ser gene; serrate.
SOURCE D.melanogaster pupa, cDNA to mRNA.
ORGANISM Drosophila melanogaster
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (bases 1 to 5546)
AUTHORS Fleming,R.J., Scottgale,T.N., Diederich,R.J. and
Artavanis-Tsakonas,S.
TITLE The gene Serrate encodes a putative EGF-like transmembrane protein
essential for proper ectodermal development in Drosophila
melanogaster
JOURNAL Genes Dev. 4, 2188-2201 (1990)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by R.J.Fleming, 28-JUN-1990.
Author address: R.J.Fleming
Yale University
Dept of Biology
KBT 1104
New Haven, CT 06511
email: WHAKRIA@YALEVM
FEATURES Location/Qualifiers
mRNA <1..5546
/note="serrate protein"
CDS 443..4657
/note="serrate protein precursor"
/codon_start=443
sig_peptide 443..679
/note="serrate protein signal peptide"
/codon_start=443
mat_peptide 680..4657
/note="serrate protein"
/codon_start=680
BASE COUNT 1384 a 1446 c 1504 g 1212 t
ORIGIN Chromosome 3 97F.
1 ccgagtcgag cgccgtgctt cgagcggtga tgagcccctt ttctgtcaac gctaaagatc
61 tacaaaacat cagcgcctat caagtggaag tgtcaagtgt gaacaaaaca aaaacgagag
121 aagcacatac taaggtccat ataaataata aataataatt gtgtgtgata acaacattat
181 ccaaacaaaa ccaaacaaaa cgaaggcaaa gtggagaaaa tgatacagca tccagagtac
241 ggccagttat tcagctatcc agagcaagtg tagtgtggca aaatagaaac aaacaaaggc
301 accaaaatct gcatacatgg gctaattaag gctgcccagc gaatttacat ttgtgtggtg
361 ccaatccaga gtgaatccga aacaaactcc atctagatcg ccaaccagca tcacgctcgc
421 aaacgccccc agaatgtaca aaatgtttag gaaacatttt cggcgaaaac cagctacgtc
481 gtcgtcgttg gagtcaacaa tagaatcagc agacagcctg ggaatgtcca agaagacggc
541 gacaaaaagg cagcgtccga ggcatcgggt acccaaaatc gcgaccctgc catcgacgat
601 ccgcgattgt cgatcattaa agtctgcctg caacttaatt gctttaattt taatactgtt
661 agtccataag atatccgcag ctggtaactt cgagctggaa atattagaaa tctcaaatac
721 caacagccat ctactcaacg gctattgctg cggcatgcca gcggaactta gggccaccaa
781 gacgataggc tgctcgccat gcacgacggc attccggctg tgcctgaagg agtaccagac
841 cacggagcag ggtgccagca tatccacggg ctgttcgttt ggcaacgcca ccaccaagat
901 actgggtggc tccagctttg tgctcagcga tccgggtgtg ggagccattg tgctgccctt
961 tacgtttcgt tggacgaagt cgtttacgct gatactgcag gcgttggata tgtacaacac
1021 atcctatcca gatgcggaga ggttaattga ggaaacatca tactcgggcg tgatactgcc
1081 gtcgccggag tggaagacgc tggaccacat cgggcggaac gcgcggatca cctaccgtgt
1141 ccgggtgcaa tgcgccgtta cctactacaa cacgacctgc acgaccttct gccgtccgcg
1201 ggacgatcag ttcggtcact acgcctgcgg ctccgagggt cagaagctct gcctgaatgg
1261 ctggcagggc gtcaactgcg aggaggccat atgcaaggcg ggctgcgacc ccgtccacgg
1321 caagtgcgat cgtccggggg aatgcgaatg cagacccggc tggcgtggtc cattgtgcaa
1381 cgagtgcatg gtctatcccg gctgcaagca tggttcctgc aacggcagcg cctggaaatg
1441 cgtgtgcgac accaactggg gtggcatatt gtgcgatcaa gatttaaatt tctgcggcac
1501 ccatgaaccc tgcaagcacg gcggcacctg cgaaaatacc gctccggaca aatatcggtg
1561 cacatgcgcc gagggcctct cgggcgagca gtgcgagatc gtggagcacc catgtgccac
1621 caggccatgc cgcaacggcg gcacatgcac actcaagacg agtaaccgaa ctcaagccca
1681 agtgtatcgc acatcacatg gcaggagcaa catgggccgg ccggtaagac gcagcagttc
1741 gatgcgcagc ctggatcacc tgcggccgga ggggcaggcg ctgaatggca gcagctcctc
1801 gggattggtg tccctaggtt cgctgcagct gcagcagcaa ctggcccccg acttcacttg
1861 cgactgcgca gccggatgga cgggaccgac atgcgaaata aatatcgacg agtgcgccgg
1921 gggtccctgc gagcatggtg gcacttgcat cgatctaatc ggtggctttc gatgtgaatg
1981 tccgccggag tggcatggcg atgtctgtca ggtggatgtg aacgagtgcg aggcgccgca
2041 ttccgccgga atcgctgcga acgcattgct gaccaccaca gccaccgcga ttattggtag
2101 taatctgagc agtactgctc ttctggccgc tctgaccagt gcagtggcat ccacatcctt
2161 ggccatcgga ccctgcatca atgccaagga gtgtcgcaat cagccgggtt cctttgcctg
2221 catctgcaag gagggctggg gcggagtgac ctgtgccgag aatctagatg actgtgtggg
2281 tcagtgccgg aatggagcca cctgcattga tctggtcaac gactataggt gcgcctgtgc
2341 ctctggattc acgggtcgcg attgcgagac ggacatagac gagtgcgcca cttccccgtg
2401 ccgaaacgga ggcgaatgtg tggacatggt gggcaaattc aattgcattt gcccacttgg
2461 ctactcgggt tctctgtgcg aggaggccaa ggagaactgc acaccgtcgc catgtttgga
2521 gggtcactgc ctcaacacgc ccgaaggata ctactgccat tgtccaccgg atcgcgccgg
2581 aaagcactgc gagcaactgc gtccgctctg ctcccagccg ccctgcaacg agggctgctt
2641 cgccaatgtc agcctagcga cgtcagcgac aacgacgacg acaaccacca caacggcgac
2701 aacgacaagg aagatggcca agccaagcgg attgccctgc agcggacacg gcagctgcga
2761 gatgagcgac gtgggcacct tctgcaaatg ccatgtgggc cacaccggca ccttctgcga
2821 gcacaatctc aacgaatgct cgccgaatcc ttgtcgaaat gggggaattt gccttgacgg
2881 cgacggcgat tttacatgcg agtgcatgtc gggctggaca ggtaaacgct gctcggagcg
2941 cgctacaggt tgttatgccg gtcagtgcca gaatggtggt acctgcatgc ctggagcccc
3001 ggacaaggct ctgcagccgc attgccgctg tgcgccaggt tggactggtc tgttttgcgc
3061 cgaggctatt gaccagtgtc gcgggcagcc gtgccacaat ggcggaacgt gcgagtcggg
3121 agcgggctgg ttccgctgcg tctgcgctca gggattctct ggtccagact gccgcatcaa
3181 tgtgaacgag tgctcgccac agccttgcca gggcggtgcc acctgcatcg acggaatcgg
3241 tggatacagc tgcatctgcc caccaggaag gcatggattg cggtgtgaaa ttttgctctc
3301 cgatcccaag tccgcctgcc agaacgcaag caacactatc tctccgtata cagctctaaa
3361 ccgaagccaa aactggctgg atattgctct aaccggaaga acagaagacg atgagaactg
3421 caatgcgtgt gtctgcgaaa acggcacctc tcggtgcacg aatctctggt gtggattgcc
3481 caattgctat aaggtggatc cgctctccaa gtcctcgaat ctgtccggtg tttgcaaaca
3541 gcacgaggtg tgcgttccgg cactgagtga gacatgcctg tcatcgcctt gtaatgttcg
3601 tggagattgc cgggcactgg aaccatcgcg tcgggttgct ccaccccgac tgccagccaa
3661 atctagctgc tggcccaatc aggccgtggt caacgagaac tgcgcccgac tcaccatcct
3721 tttggccctg gagcgagtgg gcaagggagc ttcggtggag ggtctctgct ccctggtaag
3781 ggtgctgctg gctgcccagt tgatcaagaa gccggcgagt acttttggcc aggatccggg
3841 aatgcttatg gtgctctgcg atctcaaaac gggcaccaat gataccgttg aactaactgt
3901 gtcgtccagt aaattaaatg atccccagct gccagtggcg gtgggtctgc tgggtgaact
3961 cctgagctcc aggcagttga atggcatcca gcggcgcaag gaactggagc tgcagcatgc
4021 aaaattggct gccctcacct ccattgtgga ggtcaagttg gaaacggccc gcgtggccga
4081 tggatcgggt catagtctgc tgataggagt gctatgcggt gtctttatag tcctggtggg
4141 attctcggtg ttcatcagtc tttactggaa acagcgtctg gcttatcgca ccagttcggg
4201 aatgaactta actccctccc tggatgcact gcgtcacgag gaggagaagt cgaataatct
4261 gcagaacgag gagaatctgc gaaggtatac aaatccgctg aagggcagca ccagttccct
4321 aagagcggcc accggcatgg aactaagcct caatcccgct ccggaattag ccgcctcggc
4381 ggcgagtagt tccgccttgc acagatcgca gccactattc ccgccatgcg atttcgagcg
4441 tgagctggac tccagtacgg gcctgaagca ggcgcacaag cggagctcac agattctgct
4501 gcacaaaacc caaaactcgg acatgcggaa gaacactgtg ggctcgctgg acagtccgcg
4561 taaggacttt ggcaagcggt cgatcaactg caagtccatg ccaccctctt cgggcgacga
4621 gggctccgat gtccttgcca ccactgtgat ggtttagccg tgatctcacc aaccaaccaa
4681 tcaagaaacc aaccagccgc ccacagccag ctcaaagttc caattgccac agcacgggcg
4741 ctatttccaa gtgcattagt agcgtaatta aaactaggat attgttaagg ataccaaggt
4801 aggccacaac ggagtggctc tgttgaaaac gtaaagttct aaaaatccag gtctctcaga
4861 caaagatgag gtacacaaat aaattggcta gttaatcaag catgttatgg ccacgggatg
4921 ggcaaattta tttgtatacc tgatcttatc ttaatactaa accagttttc tactattttt
4981 tttttgtgga tcaagcttaa aagttcagct aggcaggcgt tttccgcagt gccatgtcga
5041 tgtggaagcc caaaatattt aggttagata gtgtaatttc gaactcttct cttcgctaag
5101 caacatccta cacagtgtga tatttagtgt aacccaggcg cgcatttaca ttcaattaaa
5161 gacaatgata tataaatata aacgaaatca actccttggc tagcacaagc tgtatgtata
5221 tagttctcat ttaggatcgt cgcgctctat attgtgtata agctgtaaat actgtaaatt
5281 agcagttacc gttattgtat tttgtctata gttagattgg tactattaaa ctaagaacca
5341 gccgcaacgc gttagacttt aaaagttgtt tgcaattgta cgcaataata tagttttatg
5401 ctcgtagtta ggtagctgtg taaccgggta agattcaaac gattttgtac tgtattatat
5461 acctatctgt gtagtaatat ttatttatta tattaaattt gatctagacg caataaagta
5521 atatcaataa agatagtaaa agacat
//