GenBank-Updates@genbank.bio.net (01/19/91)
LOCUS HUMAMY1 292 bp ds-DNA PRI 19-JAN-1991
DEFINITION Human salivary alpha-amylase (AMY1) gene, exon 9.
ACCESSION M18674
KEYWORDS alpha-amylase; amylase.
SOURCE Human salivary gland DNA, clone N1.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 292)
AUTHORS Gumucio,D.L., Wiebauer,K., Caldwell,R.M., Samuelson,L.C. and
Meisler,M.H.
TITLE Concerted Evolution of Human Amylase Genes
JOURNAL Mol. Cell. Biol. 8, 1197-1205 (1988)
STANDARD simple staff_entry
COMMENT Draft entry and computer_readable copy of sequence kindly
submitted
by M.Meisler 15_MAR-1988
Base 91 removed at request of author.
FEATURES Location/Qualifiers
intron <1..22
/note="alpha-amylase, intron H"
CDS <23..>148
/note="alpha-amylase, exon 9 (AA at 24) /map='1p21'
/hgml_locus_uid='LJ0263N'"
/partial
intron 149..>292
/note="alpha-amylase, intron I"
BASE COUNT 87 a 41 c 63 g 101 t
ORIGIN
1 ttatatgtat tgtccttttt aggaacatgg ttaatttccg caatgtagtg gatggccagc
61 cttttacaaa ctggtatgat aatgggagca accaagtggc ttttgggaga ggaaacagag
121 gattcattgt tttcaacaat gatgactggt aagtaaatat caattaaaaa taatattttg
181 taccagtatg ttcttggttt attctttttt ttttctgttc attgacattt atcatatctg
241 aaaaatcatg tagtcagtgg agcgagaaga caatagagat ccccgggcga gc
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA101 941 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 1.
ACCESSION M18715 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 1 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 543 to 931)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 941)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 543 to 931)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 941)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
exon 764..931
/note="alpha-amylase, exon 1 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 932..>941
/note="alpha-amylase, intron A"
BASE COUNT 258 a 160 c 211 g 312 t
ORIGIN 193 bp upstream of XbaI site; chromosome 1p21.
1 gcattcaagt taactcttcc ccttggtatc tgtacatacc tttgatgtca gtgtttagta
61 cacgtggctt ggtcacttca tggctaaaaa cgtgcttgtg gaagacaagt ctggcttggt
121 gagtctgtgt ggtcagcagt ctctgatccg tgcagggtat taatgtgtca gggctgagtg
181 ttctgagatt tatctagagg ctgggaaggg ctcctgaacc agttgtttcc gtcttgtcgg
241 tctgtcaggg ttggaaagtc caagccatag gacccagttt cctttcttag cttacgttat
301 ctaccagagc accgtgggct gttacttgcc ttgagttgga agcggttcgc atttataccg
361 gtaaatgtat tcatcctttt aatttatgta aagtttttta gtatgcaatt ctcgatcttt
421 taagagttga caacaaattt tggttttctg ctgttatgtg agaacattag gccacagcaa
481 catgtcattg tgtaaggaaa aataaaagtg ctaccatatg caaaaaaaaa aaaaaaaaga
541 aaagaaaaga aacattaatg tctaagaggt cattgagatg atttccatga gagacttttt
601 gatgttcttc accagttagg attattattg ataatccttt tcagattatg aataaacagt
661 ttgccctcaa gtatttattc atgctactat ttacattgta aaatgtgctt cttacaggaa
721 tataaatagt ttctggaaag gacactgaca acttcaaagc aaaatgaagc tcttttggtt
781 gcttttcacc attgggttct gctgggctca gtattcctca aatacacaac aaggacgaac
841 atctattgtt catctgtttg aatggcgatg ggttgatatt gctcttgaat gtgagcgata
901 tttagctccc aagggatttg gaggggttca ggtgggtatg a
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA102 167 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 2.
ACCESSION M18717 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 2 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 157)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 167)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 157)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 167)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron A"
exon 11..157
/note="alpha-amylase, exon 2 /map='1p21'
/hgml_locus_uid='LJ0263N''"
intron 158..>167
/note="alpha-amylase, intron B"
BASE COUNT 59 a 28 c 35 g 45 t
ORIGIN About 400 bp downstream of segment 1; chromosome 1p21.
1 taatttgtag gtctctccac caaatgaaaa tgttgccatt cacaaccctt tcagaccttg
61 gtgggaaaga taccaaccag ttagctataa attatgcaca agatctggaa atgaagatga
121 atttagaaac atggtgacta gatgcaacaa tgttggggta agtgaat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA103 218 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 3.
ACCESSION M18719 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 3 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 208)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 218)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 208)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 218)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron B"
exon 11..208
/note="alpha-amylase, exon 3 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 209..>218
/note="alpha-amylase, intron C"
BASE COUNT 61 a 29 c 55 g 73 t
ORIGIN About 800 bp downstream of segment 2; chromosome 1p21.
1 tgttttctag gttcgtattt atgtggatgc tgtaattaat catatgtgtg gtaatgctgt
61 gagtgcagga acaagcagta cctgtggaag ttacttcaac cctggaagta gggactttcc
121 agcagtccca tattctggat gggattttaa tgatggtaaa tgtaaaactg gaagtggaga
181 tatcgagaac tataatgatg ctactcaggt aatttttt
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA104 251 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 4.
ACCESSION M18721 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 4 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 241)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 251)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 241)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 251)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
kindly provided by A.Horii (14-MAR-1988). [Gene 28, 263-270
(1984)] also sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron C"
exon 11..241
/note="alpha-amylase, exon 4 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 242..>251
/note="alpha-amylase, intron D"
BASE COUNT 69 a 50 c 60 g 72 t
ORIGIN About 600 bp downstream of segment 3; chromosome 1p21.
1 acctcaacag gtcagagatt gtcgtctgtc tggtcttctc gatcttgcac tggggaagga
61 ttatgtgcgt tctaagattg ccgaatatat gaaccatctc attgacattg gtgttgcagg
121 gttcagaatt gatgcttcca agcacatgtg gcctggagac ataaaggcaa ttttggacaa
181 actgcataat ctaaacagta actggttccc ggaaggtagt aaacctttca tttaccagga
241 ggtacgtcaa t
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA105 154 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 5.
ACCESSION M18723 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 5 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 144)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 154)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 144)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 154)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron D"
exon 11..144
/note="alpha-amylase, exon 5 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 145..>154
/note="alpha-amylase, intron E"
BASE COUNT 49 a 21 c 40 g 44 t
ORIGIN About 800 bp downstream of segment 4; chromosome 1p21.
1 tttcttctag gtaattgatc tgggtggtga gccaattaaa agcagtgact actttggtaa
61 tggccgggtg acagaattca agtatggtgc aaaactcggc acagttattc gcaagtggaa
121 tggagagaag atgtcttact taaagtaaat aaat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA106 143 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 6.
ACCESSION M18725 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 6 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 133)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 143)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 133)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 143)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron E"
exon 11..133
/note="alpha-amylase, exon 6 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 134..>143
/note="alpha-amylase, intron F"
BASE COUNT 40 a 28 c 40 g 35 t
ORIGIN About 800 bp downstream of segment 5; chromosome 1p21.
1 tcaaaaatag gaactgggga gaaggttggg gtttcatgcc ttctgacaga gcgcttgtct
61 ttgtggataa ccatgacaat caacgaggac atggcgctgg aggagcctct atacttacct
121 tctgggatgc taggtaaaaa acc
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA107 120 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 7.
ACCESSION M18727 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 7 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 110)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 120)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 110)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 120)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron F"
exon 11..110
/note="alpha-amylase, exon 7 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 111..>120
/note="alpha-amylase, intron G"
BASE COUNT 35 a 18 c 26 g 40 t 1 others
ORIGIN 94 bp downstream of segment 6; chromosome 1p21.
1 taactttcag gctgtacaaa atggcagttg gatttatgct tgctcatcct tatggattta
61 cacgagtaat gtcaagctac cgttggccaa gatattttga aaatggaaan gtaagttttg
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA108 139 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 8.
ACCESSION M18782 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 8 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 129)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 139)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 129)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 139)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron G"
exon 11..129
/note="alpha-amylase, exon 8 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 130..>139
/note="alpha-amylase, intron H"
BASE COUNT 47 a 19 c 35 g 38 t
ORIGIN bout 2000 bp downstream of segment 7; chromosome 1p21.
1 tgtaattaag gatgttaatg attgggttgg gccaccaaat gataatggag taactaaaga
61 agttactatt aatccagaca ctacttgtgg caatgactgg gtctgtgaac atcgatggcg
121 ccaaataagg tgagaatat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA109 146 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 9.
ACCESSION M18784 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 9 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 136)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 146)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 136)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 146)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the pancreatic
alpha-amylase mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggests the possibility
of gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron H"
exon 11..136
/note="alpha-amylase, exon 9 /map='1p21'
/hgml_locus_uid='LJ0263N'"
intron 137..>146
/note="alpha-amylase, intron I"
BASE COUNT 44 a 19 c 39 g 44 t
ORIGIN 110 bp downstream of segment 8; chromosome 1p21.
1 gtgtttttag gaacatggtt aatttccgca atgtagtgga tggccagcct tttacaaact
61 ggtatgataa tgggagcaac caagtggctt ttgggagagg aaacagagga ttcattgttt
121 tcaacaatga tgactggtaa gtaaat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMYA110 250 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human salivary alpha-amylase (amy1) gene, exon 10.
ACCESSION M18786 K02214
KEYWORDS alpha-amylase; amylase.
SEGMENT 10 of 10
SOURCE Human salivary gland, cDNA to mRNA, clones pHSA7 and pHSA15 and
[Gene 28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50,
371-372 (1986)] and Human cosmid library DNA, clone cosP2 [Gene 60,
57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 240)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 250)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 240)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 250)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988). [Gene 28, 263-270 (1984)] also
sequenced the
pancreatic alpha-amylase mRNA. Comparison of the two alpha-amylase
nucleotide sequences reveals 96% homology in the coding region.
Comparison of the sequences of human alpha-amylase cDNAs with those
for mouse suggests the possibility of gene conversion between the
two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron I"
CDS join(M18715:764..931,M18717:11..157,M18719:11..208,
M18721:11..241,M18723:11..144,M18725:11..133,
M18727:11..110,M18782:11..129,M18784:11..136,11..200)
/note="alpha-amylase"
/codon_start=764
exon 11..200
/note="alpha-amylase, exon 10 /map='1p21'
/hgml_locus_uid='LJ0263N'"
BASE COUNT 78 a 43 c 40 g 89 t
ORIGIN About 1300 bp downstream of segment 9; chromosome 1p21.
1 tattttacag gacattttct ttaactttgc aaactggtct tcctgctggc acatactgtg
61 atgtcatttc tggagataaa attaatggca actgcacagg cattaaaatc tacgtttctg
121 atgatggcaa agctcatttt tctattagta actctgctga agatccattt attgcaattc
181 atgctgaatc taaattgtaa aatttaaaat taaatgcaaa tccgcaaagc aatagctaag
241 tgtgtttctt
//