GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAPOBA2 13872 bp ss-mRNA PRI 08-MAY-1991
DEFINITION Human apolipoprotein B-100 mRNA, starting at exon 3.
ACCESSION M15051 M15054
KEYWORDS apolipoprotein B-100.
SEGMENT 2 of 2
SOURCE Human (adult) liver, cDNA to mRNA (library of E.F.Fritsch), clones
lambda-B[4,8,16,19,23,26,42] [EMBO J. 5, 3495-3507 (1986)], clones
lambda-B[1,2,6,7,25] [EMBO J. 5, 3495-3507 (1986)],[Biochemistry
25, 5351-5357 (1986)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 333 to 5576)
AUTHORS Cladaras,C., Hadzopoulou-Cladaras,M., Avila,R., Nussbaum,A.L.,
Nicolosi,R. and Zannis,V.I.
TITLE Complementary DNA derived structure of the amino-terminal domain of
human apolipoprotein B and size of its messenger RNA transcript
JOURNAL Biochemistry 25, 5351-5357 (1986)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 13872)
AUTHORS Cladaras,C., Hadzopoulou-Cladaras,M., Nolte,R.T., Atkinson,D. and
Zannis,V.I.
TITLE The complete sequence and structural analysis of human
apolipoprotein B-100: Relationship between apoB-100 and apoB-48
forms
JOURNAL EMBO J. 5, 3495-3507 (1986)
STANDARD full staff_review
COMMENT Computer-readable sequence for [EMBO J. 5, 3495-3507 (1986)],
[Biochemistry 25, 5351-5357 (1986)] kindly provided by
C.Cladaras, 12-MAR-1987.
FEATURES Location/Qualifiers
prim_transcript <1..13872
/note="apoB100 mRNA"
CDS join(M15053:283..355,M15053:670..708,1..13571)
/note="apolipoprotein B-100 precursor /nomgen='APOB'
/map='2p24-p23' /hgml_locus_uid='LD0091N'"
/codon_start=283
mat_peptide join(M15053:355..355,M15053:670..708,1..13568)
/note="apolipoprotein B-100"
/codon_start=355
exon 1..13571
/note="apolipoprotein B-100 precursor /nomgen='APOB'
/map='2p24-p23' /hgml_locus_uid='LD0091N'"
mat_peptide 1..13568
/note="apolipoprotein B-100"
variation 3204..3204
/note="g in lambda-B25; c in lambda B1"
BASE COUNT 4338 a 3150 c 2811 g 3573 t
ORIGIN Undetermined number of bp after segment 1.
1 aagatgcgac ccgattcaag cacctccgga agtacacata caactatgag gctgagagtt
61 ccagtggagt ccctgggact gctgattcaa gaagtgccac caggatcaac tgcaaggttg
121 agctggaggt tccccagctc tgcagcttca tcctgaagac cagccagtgc accctgaaag
181 aggtgtatgg cttcaaccct gagggcaaag ccttgctgaa gaaaaccaag aactctgagg
241 agtttgctgc agccatgtcc aggtatgagc tcaagctggc cattccagaa gggaagcagg
301 ttttccttta cccggagaaa gatgaaccta cttacatcct gaacatcaag aggggcatca
361 tttctgccct cctggttccc ccagagacag aagaagccaa gcaagtgttg tttctggata
421 ccgtgtatgg aaactgctcc actcacttta ccgtcaagac gaggaagggc aatgtggcaa
481 cagaaatatc cactgaaaga gacctgggcc agtgtgatcg cttcaagccc atccgcacag
541 gcatcagccc acttgctctc atcaaaggca tgacccgccc cttgtcaact ctgatcagca
601 gcagccagtc ctgtcagtac acactggacg ctaagaggaa gcatgtggca gaagccatct
661 gcaaggagca acacctcttc ctgcctttct cctacaagaa taagtatggg atggtagcac
721 aagtgacaca gactttgaaa cttgaagaca caccaaagat caacagccgc ttctttggtg
781 aaggtactaa gaagatgggc ctcgcatttg agagcaccaa atccacatca cctccaaagc
841 aggccgaagc tgttttgaag actctccagg aactgaaaaa actaaccatc tctgagcaaa
901 atatccagag agctaatctc ttcaataagc tggttactga gctgagaggc ctcagtgatg
961 aagcagtcac atctctcttg ccacagctga ttgaggtgtc cagccccatc actttacaag
1021 ccttggttca gtgtggacag cctcagtgct ccactcacat cctccagtgg ctgaaacgtg
1081 tgcatgccaa cccccttctg atagatgtgg tcacctacct ggtggccctg atccccgagc
1141 cctcagcaca gcagctgcga gagatcttca acatggcgag ggatcagcgc agccgagcca
1201 ccttgtatgc gctgagccac gcggtcaaca actatcataa gacaaaccct acagggaccc
1261 aggagctgct ggacattgct aattacctga tggaacagat tcaagatgac tgcactgggg
1321 atgaagatta cacctatttg attctgcggg tcattggaaa tatgggccaa accatggagc
1381 agttaactcc agaactcaag tcttcaatcc tgaaatgtgt ccaaagtaca aagccatcac
1441 tgatgatcca gaaagctgcc atccaggctc tgcggaaaat ggagcctaaa gacaaggacc
1501 aggaggttct tcttcagact ttccttgatg atgcttctcc gggagataag cgactggctg
1561 cctatcttat gttgatgagg agtccttcac aggcagatat taacaaaatt gtccaaattc
1621 taccatggga acagaatgag caagtgaaga actttgtggc ttcccatatt gccaatatct
1681 tgaactcaga agaattggat atccaagatc tgaaaaagtt agtgaaagaa gttctgaaag
1741 aatctcaact tccaactgtc atggacttca gaaaattctc tcggaactat caactctaca
1801 aatctgtttc tcttccatca cttgacccag cctcagccaa aatagaaggg aatcttatat
1861 ttgatccaaa taactacctt cctaaagaaa gcatgctgaa aactaccctc actgcctttg
1921 gatttgcttc agctgacctc atcgagattg gcttggaagg aaaaggcttt gagccaacat
1981 tggaagctct ttttgggaag caaggatttt tcccagacag tgtcaacaaa gctttgtact
2041 gggttaatgg tcaagttcct gatggtgtct ctaaggtctt agtggaccac tttggctata
2101 ccaaagatga taaacatgag caggatatgg taaatggaat aatgctcagt gttgagaagc
2161 tgattaaaga tttgaaatcc aaagaagtcc cggaagccag agcctacctc cgcatcttgg
2221 gagaggagct tggttttgcc agtctccatg acctccagct cctgggaaag ctgcttctga
2281 tgggtgcccg cactctgcag gggatccccc agatgattgg agaggtcatc aggaagggct
2341 caaagaatga cttttttctt cactacatct tcatggagaa tgcctttgaa ctccccactg
2401 gagctggatt acagttgcaa atatcttcat ctggagtcat tgctcccgga gccaaggctg
2461 gagtaaaact ggaagtagcc aacatgcagg ctgaactggt ggcaaaaccc tccgtgtctg
2521 tggagtttgt gacaaatatg ggcatcatca ttccggactt cgctaggagt ggggtccaga
2581 tgaacaccaa cttcttccac gagtcgggtc tggaggctca tgttgcccta aaagctggga
2641 agctgaagtt tatcattcct tccccaaaga gaccagtcaa gctgctcagt ggaggcaaca
2701 cattacattt ggtctctacc accaaaacgg aggtgatccc acctctcatt gagaacaggc
2761 agtcctggtc agtttgcaag caagtctttc ctggcctgaa ttactgcacc tcaggcgctt
2821 actccaacgc cagctccaca gactccgcct cctactatcc gctgaccggg gacaccagat
2881 tagagctgga actgaggcct acaggagaga ttgagcagta ttctgtcagc gcaacctatg
2941 agctccagag agaggacaga gccttggtgg ataccctgaa gtttgtaact caagcagaag
3001 gtgcgaagca gactgaggct accatgacat tcaaatataa tcggcagagt atgaccttgt
3061 ccagtgaagt ccaaattccg gattttgatg ttgacctcgg aacaatcctc agagttaatg
3121 atgaatctac tgagggcaaa acgtcttaca gactcaccct ggacattcag aacaagaaaa
3181 ttactgaggt cgccctcatg ggcgacctaa gttgtgacac aaaggaagaa agaaaaatca
3241 agggtgttat ttccataccc cgtttgcaag cagaagccag aagtgagatc ctcgcccact
3301 ggtcgcctgc caaactgctt ctccaaatgg actcatctgc tacagcttat ggctccacag
3361 tttccaagag ggtggcatgg cattatgatg aagagaagat tgaatttgaa tggaacacag
3421 gcaccaatgt agataccaaa aaaatgactt ccaatttccc tgtggatctc tccgattatc
3481 ctaagagctt gcatatgtat gctaatagac tcctggatca cagagtccct caaacagaca
3541 tgactttccg gcacgtgggt tccaaattaa tagttgcaat gagctcatgg cttcagaagg
3601 catctgggag tcttccttat acccagactt tgcaagacca cctcaatagc ctgaaggagt
3661 tcaacctcca gaacatggga ttgccagact tccacatccc agaaaacctc ttcttaaaaa
3721 gcgatggccg ggtcaaatat accttgaaca agaacagttt gaaaattgag attcctttgc
3781 cttttggtgg caaatcctcc agagatctaa agatgttaga gactgttagg acaccagccc
3841 tccacttcaa gtctgtggga ttccatctgc catctcgaga gttccaagtc cctactttta
3901 ccattcccaa gttgtatcaa ctgcaagtgc ctctcctggg tgttctagac ctctccacga
3961 atgtctacag caacttgtac aactggtccg cctcctacag tggtggcaac accagcacag
4021 accatttcag ccttcgggct cgttaccaca tgaaggctga ctctgtggtt gacctgcttt
4081 cctacaatgt gcaaggatct ggagaaacaa catatgacca caagaatacg tctacactat
4141 catgtgatgg gtctctacgc cacaaatttc tagattcgaa tatcaaattc agtcatgtag
4201 aaaaacttgg aaacaaccca gtctcaaaag gtttactaat attcgatgca tctagttcca
4261 tgggaccaca gatgtctgct tcagttcatt tggactccaa aaagaaacag catttgtttg
4321 tcaaagaagt caagattgat gggcagttca gagtctcttc gttctatgct aaaggcacat
4381 atggcctgtc ttgtcagagg gatcctaaca ctggccggct caatggagag tccaacctga
4441 ggtttaactc ctcctacctc caaggcacca accagataac aggaagatat gaagatggaa
4501 ccctctccct cacctccacc tctgatctgc aaagtggcat cattaaaaat actgcttccc
4561 taaagtatga gaactacgag ctgactttaa aatctgacac caatgggaag tataagaact
4621 ttgccacttc taacaagatg gatatgacct tctctaagca aaatgcactg ctgcgttctg
4681 aatatcaggc tgattacgag tcattgaggt tcttcagcct gctttctgga tcactaaatt
4741 cccatggtct tgagttaaat gctgacatct taggcactga caaaattaat agtggtgctc
4801 acaaggcgac actaaggatt ggccaagatg gaatatctac cagtgcaacg accaacttga
4861 agtgtagtct cctggtgctg gagaatgagc tgaatgcaga gcttggcctc tctggggcat
4921 ctatgaaatt aacaacaaat ggccgcttca gggaacacaa tgcaaaattc agtctggatg
4981 ggaaagccgc cctcacagag ctatcactgg gaagtgctta tcaggccatg attctgggtg
5041 tcgacagcaa aaacattttc aacttcaagg tcagtcaaga aggacttaag ctctcaaatg
5101 acatgatggg ctcatatgct gaaatgaaat ttgaccacac aaacagtctg aacattgcag
5161 gcttatcact ggacttctct tcaaaacttg acaacattta cagctctgac aagttttata
5221 agcaaactgt taatttacag ctacagccct attctctggt aactacttta aacagtgacc
5281 tgaaatacaa tgctctggat ctcaccaaca atgggaaact acggctagaa cccctgaagc
5341 tgcatgtggc tggtaaccta aaaggagcct accaaaataa tgaaataaaa cacatctatg
5401 ccatctcttc tgctgcctta tcagcaagct ataaagcaga cactgttgct aaggttcagg
5461 gtgtggagtt tagccatcgg ctcaacacag acatcgctgg gctggcttca gccattgaca
5521 tgagcacaaa ctataattca gactcactgc atttcagcaa tgtcttccgt tctgtaatgg
5581 ccccgtttac catgaccatc gatgcacata caaatggcaa tgggaaactc gctctctggg
5641 gagaacatac tgggcagctg tatagcaaat tcctgttgaa agcagaacct ctggcattta
5701 ctttctctca tgattacaaa ggctccacaa gtcatcatct cgtgtctagg aaaagcatca
5761 gtgcagctct tgaacacaaa gtcagtgccc tgcttactcc agctgagcag acaggcacct
5821 ggaaactcaa gacccaattt aacaacaatg aatacagcca ggacttggat gcttacaaca
5881 ctaaagataa aattggcgtg gagcttactg gacgaactct ggctgaccta actctactag
5941 actccccaat taaagtgcca cttttactca gtgagcccat caatatcatt gatgctttag
6001 agatgagaga tgccgttgag aagccccaag aatttacaat tgttgctttt gtaaagtatg
6061 ataaaaacca agatgttcac tccattaacc tcccattttt tgagaccttg caagaatatt
6121 ttgagaggaa tcgacaaacc attatagttg tactggaaaa cgtacagaga aagctgaagc
6181 acatcaatat tgatcaattt gtaagaaaat acagagcagc cctgggaaaa ctcccacagc
6241 aagctaatga ttatctgaat tcattcaatt gggagagaca agtttcacat gccaaggaga
6301 aactgactgc tctcacaaaa aagtatagaa ttacagaaaa tgatatacaa attgcattag
6361 atgatgccaa aatcaacttt aatgaaaaac tatctcaact gcagacatat atgatacaat
6421 ttgatcagta tattaaagat agttatgatt tacatgattt gaaaatagct attgctaata
6481 ttattgatga aatcattgaa aaattaaaaa gtcttgatga gcactatcat atccgtgtaa
6541 ttttagtaaa aacaatccat gatctacatt tgtttattga aaatattgat tttaacaaaa
6601 gtggaagtag tactgcatct tggattcaaa atgtggatac taagtaccaa atcagaatcc
6661 agatacaaga aaaactgcag cagcttaaga gacacataca gaatatagac atccagcacc
6721 tagctggaaa gttaaaacaa cacattgagg ctattgatgt tagagtgctt ttagatcaat
6781 tgggaactac aatttcattt gaaagaataa atgacgttct tgagcatgtc aaacactttg
6841 ttataaatct tattggggat tttgaagtag ctgagaaaat caatgccttc agagccaaag
6901 tccatgagtt aatcgagagg tatgaagtag accaacaaat ccaggtttta atggataaat
6961 tagtagagtt ggcccaccaa tacaagttga aggagactat tcagaagcta agcaatgtcc
7021 tacaacaagt taagataaaa gattactttg agaaattagt tggatttatt gatgatgctg
7081 tcaagaagct taatgaatta tcttttaaaa cattcattga agatgttaac aaattccttg
7141 acatgttgat aaagaaatta aagtcatttg attaccacca gtttgtagat gaaaccaatg
7201 acaaaatccg tgaggtgact cagagactca atggtgaaat tcaggctctg gaactaccac
7261 aaaaagctga agcattaaaa ctgtttttag aggaaaccaa ggccacagtt gcagtgtatc
7321 tggaaagcct acaggacacc aaaataacct taatcatcaa ttggttacag gaggctttaa
7381 gttcagcatc tttggctcac atgaaggcca aattccgaga gaccctagaa gatacacgag
7441 accgaatgta tcaaatggac attcagcagg aacttcaacg atacctgtct ctggtcagcc
7501 aggtttatag cacacttgtc acctacattt ctgattggtg gactcttgct gctaagaacc
7561 ttactgactt tgcagagcaa tattctatcc aagattgggc taaacgtatg aaagcattgg
7621 tagagcaagg gttcactgtt cctgaaatca agaccatcct tgggaccatg cctgcctttg
7681 aagtcagtct tcaggctctt cagaaagcta ccttccagac acctgatttt atagtccccc
7741 taacagattt gaggattcca tcagttcaga taaacttcaa agacttaaaa aatataaaaa
7801 tcccatccag gttttccaca ccagaattta ccatccttaa caccttccac attccttcct
7861 ttacaattga ctttgtagaa atgaaagtaa agatcatcag aaccattgac cagatgctga
7921 acagtgagct gcagtggccc gttccagata tatatctcag ggatctgaag gtggaggaca
7981 ttcctctagc gagaatcacc ctgccagact tccgtttacc agaaatcgca ataccagaat
8041 tcataatccc aactctcaac cttaatgatt ttcaagttcc tgaccttcac ataccagaat
8101 tccagcttcc ccacatctca cacacaattg aagtacctac ttttggcaag ctatacagta
8161 ttctgaaaat ccaatctcct cttttcacat tagatgcaaa tgctgacata gggaatggaa
8221 ccacctcagc aaacgaagca ggtatcgcag cttccatcac tgccaaagga gagtccaaat
8281 tagaagttct caattttgat tttcaagcaa atgcacaact ctcaaaccct aagattaatc
8341 cgctggctct gaaggagtca gtgaagttct ccagcaagta cctgagaacg gagcatggga
8401 gtgaaatgct gttttttgga aatgccattg agggaaaatc aaacacagtg gcaagtttac
8461 acacagaaaa aaatacactg gagcttagta atggagtgat tgtcaagata aacaatcagc
8521 ttaccctgga tagcaacact aaatacttcc acaaattgaa catccccaaa ctggacttct
8581 ctagtcaggc tgacctgcgc aacgagatca agacactgtt gaaagctggc cacatagcat
8641 ggacttcttc tggaaaaggg tcatggaaat gggcctgccc cagattctca gatgagggaa
8701 cacatgaatc acaaattagt ttcaccatag aaggacccct cacttccttt ggactgtcca
8761 ataagatcaa tagcaaacac ctaagagtaa accaaaactt ggtttatgaa tctggctccc
8821 tcaacttttc taaacttgaa attcaatcac aagtcgattc ccagcatgtg ggccacagtg
8881 ttctaactgc taaaggcatg gcactgtttg gagaagggaa ggcagagttt actgggaggc
8941 atgatgctca tttaaatgga aaggttattg gaactttgaa aaattctctt ttcttttcag
9001 cccagccatt tgagatcacg gcatccacaa acaatgaagg gaatttgaaa gttcgttttc
9061 cattaaggtt aacagggaag atagacttcc tgaataacta tgcactgttt ctgagtccca
9121 gtgcccagca agcaagttgg caagtaagtg ctaggttcaa tcagtataag tacaaccaaa
9181 atttctctgc tggaaacaac gagaacatta tggaggccca tgtaggaata aatggagaag
9241 caaatctgga tttcttaaac attcctttaa caattcctga aatgcgtcta ccttacacaa
9301 taatcacaac tcctccactg aaagatttct ctctatggga aaaaacaggc ttgaaggaat
9361 tcttgaaaac gacaaagcaa tcatttgatt taagtgtaaa agctcagtat aagaaaaaca
9421 aacacaggca ttccatcaca aatcctttgg ctgtgctttg tgagtttatc agtcagagca
9481 tcaaatcctt tgacaggcat tttgaaaaaa acagaaacaa tgcattagat tttgtcacca
9541 aatcctataa tgaaacaaaa attaagtttg ataagtacaa agctgaaaaa tctcaggacg
9601 agctccccag gacctttcaa attcctggat acactgttcc agttgtcaat gttgaagtgt
9661 ctccattcac catagagatg tcggcattcg gctatgtgtt cccaaaagca gtcagcatgc
9721 ctagtttctc catcctaggt tctgacgtcc gtgtgccttc atacacatta atcctgccat
9781 cattagagct gccagtcctt catgtcccta gaaatctcaa gctttctctt ccacatttca
9841 aggaattgtg taccataagc catattttta ttcctgccat gggcaatatt acctatgatt
9901 tctcctttaa atcaagtgtc atcacactga ataccaatgc tgaacttttt aaccagtcag
9961 atattgttgc tcatctcctt tcttcatctt catctgtcat tgatgcactg cagtacaaat
10021 tagagggcac cacaagattg acaagaaaaa ggggattgaa gttagccaca gctctgtctc
10081 tgagcaacaa atttgtggag ggtagtcata acagtactgt gagcttaacc acgaaaaata
10141 tggaagtgtc agtggcaaaa accacaaaag ccgaaattcc aattttgaga atgaatttca
10201 agcaagaact taatggaaat accaagtcaa aacctactgt ctcttcctcc atggaattta
10261 agtatgattt caattcttca atgctgtact ctaccgctaa aggagcagtt gaccacaagc
10321 ttagcttgga aagcctcacc tcttactttt ccattgagtc atctaccaaa ggagatgtca
10381 agggttcggt tctttctcgg gaatattcag gaactattgc tagtgaggcc aacacttact
10441 tgaattccaa gagcacacgg tcttcagtga agctgcaggg cacttccaaa attgatgata
10501 tctggaacct tgaagtaaaa gaaaattttg ctggagaagc cacactccaa cgcatatatt
10561 ccctctggga gcacagtacg aaaaaccact tacagctaga gggcctcttt ttcaccaacg
10621 gagaacatac aagcaaagcc accctggaac tctctccatg gcaaatgtca gctcttgttc
10681 aggtccatgc aagtcagccc agttccttcc atgatttccc tgaccttggc caggaagtgg
10741 ccctgaatgc taacactaag aaccagaaga tcagatggaa aaatgaagtc cggattcatt
10801 ctgggtcttt ccagagccag gtcgagcttt ccaatgacca agaaaaggca caccttgaca
10861 ttgcaggatc cttagaagga cacctaaggt tcctcaaaaa tatcatccta ccagtctatg
10921 acaagagctt atgggatttc ctaaagctgg atgtaaccac cagcattggt aggagacagc
10981 atcttcgtgt ttcaactgcc tttgtgtaca ccaaaaaccc caatggctat tcattctcca
11041 tccctgtaaa agttttggct gataaattca ttactcctgg gctgaaacta aatgatctaa
11101 attcagttct tgtcatgcct acgttccatg tcccatttac agatcttcag gttccatcgt
11161 gcaaacttga cttcagagaa atacaaatct ataagaagct gagaacttca tcatttgccc
11221 tcaacctacc aacactcccc gaggtaaaat tccctgaagt tgatgtgtta acaaaatatt
11281 ctcaaccaga agactccttg attccctttt ttgagataac cgtgcctgaa tctcagttaa
11341 ctgtgtcccg attcacgctt ccaaaaagtg tttcagatgg cattgctgct ttggatctaa
11401 atgcagtagc caacaagatc gcagactttg agttgcccac catcatcgtg cctgagcaga
11461 ccattgagat tccctccatt aagttctctg tacctgctgg aattgtcatt ccttcctttc
11521 aagcactgac tgcacgcttt gaggtagact ctcccgtgta taatgccact tggagtgcca
11581 gtttgaaaaa caaagcagat tatgttgaaa cagtcctgga ttccacatgc agctcaaccg
11641 tacagttcct agaatatgaa ctaaatgttt tgggaacaca caaaatcgaa gatggtacgt
11701 tagcctctaa gactaaagga acacttgcac accgtgactt cagtgcagaa tatgaagaag
11761 atggcaaatt tgaaggactt caggaatggg aaggaaaagc gcacctcaat atcaaaagcc
11821 cagcgttcac cgatctccat ctgcgctacc agaaagacaa gaaaggcatc tccacctcag
11881 cagcctcccc agccgtaggc accgtgggca tggatatgga tgaagatgac gacttttcta
11941 aatggaactt ctactacagc cctcagtcct ctccagataa aaaactcacc atattcaaaa
12001 ctgagttgag ggtccgggaa tctgatgagg aaactcagat caaagttaat tgggaagaag
12061 aggcagcttc tggcttgcta acctctctga aagacaacgt gcccaaggcc acaggggtcc
12121 tttatgatta tgtcaacaag taccactggg aacacacagg gctcaccctg agagaagtgt
12181 cttcaaagct gagaagaaat ctgcagaaca atgctgagtg ggtttatcaa ggggccatta
12241 ggcaaattga tgatatcgac gtgaggttcc agaaagcagc cagtggcacc actgggacct
12301 accaagagtg gaaggacaag gcccagaatc tgtaccagga actgttgact caggaaggcc
12361 aagccagttt ccagggactc aaggataacg tgtttgatgg cttggtacga gttactcaaa
12421 aattccatat gaaagtcaag catctgattg actcactcat tgattttctg aacttcccca
12481 gattccagtt tccggggaaa cctgggatat acactaggga ggaactttgc actatgttca
12541 taagggaggt agggacggta ctgtcccagg tatattcgaa agtccataat ggttcagaaa
12601 tactgttttc ctatttccaa gacctagtga ttacacttcc tttcgagtta aggaaacata
12661 aactaataga tgtaatctcg atgtataggg aactgttgaa agatttatca aaagaagccc
12721 aagaggtatt taaagccatt cagtctctca agaccacaga ggtgctacgt aatcttcagg
12781 accttttaca attcattttc caactaatag aagataacat taaacagctg aaagagatga
12841 aatttactta tcttattaat tatatccaag atgagatcaa cacaatcttc aatgattata
12901 tcccatatgt ttttaaattg ttgaaagaaa acctatgcct taatcttcat aagttcaatg
12961 aatttattca aaacgagctt caggaagctt ctcaagagtt acagcagatc catcaataca
13021 ttatggccct tcgtgaagaa tattttgatc caagtatagt tggctggaca gtgaaatatt
13081 atgaacttga agaaaagata gtcagtctga tcaagaacct gttagttgct cttaaggact
13141 tccattctga atatattgtc agtgcctcta actttacttc ccaactctca agtcaagttg
13201 agcaatttct gcacagaaat attcaggaat atcttagcat ccttaccgat ccagatggaa
13261 aagggaaaga gaagattgca gagctttctg ccactgctca ggaaataatt aaaagccagg
13321 ccattgcgac gaagaaaata atttctgatt accaccagca gtttagatat aaactgcaag
13381 atttttcaga ccaactctct gattactatg aaaaatttat tgctgaatcc aaaagattga
13441 ttgacctgtc cattcaaaac taccacacat ttctgatata catcacggag ttactgaaaa
13501 agctgcaatc aaccacagtc atgaacccct acatgaagct tgctccagga gaacttacta
13561 tcatcctcta attttttaaa agaaatcttc aatttattct tcttttccaa ttgaactttc
13621 acatagcaca gaaaaaattc aaactgccta tattgataaa accatacagt gagccagcct
13681 tgcagtaggc agtagactat aagcagaagc acatatgaac tggacctgca ccaaagctgg
13741 caccagggct cggaaggtct ctgaactcag aaggatggca ttttttgcaa gttaaagaaa
13801 atcaggatct gagttatttt gctaaacttg ggggaggagg aacaaataaa tggagtcttt
13861 attgtgtatc at
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