GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMASLA1A 1449 bp ss-mRNA PRI 08-MAY-1991
DEFINITION Human mRNA for argininosuccinate lyase.
ACCESSION Y00753
KEYWORDS argininosuccinate lyase.
SOURCE human (Homo sapiens).
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1449)
AUTHORS Takeyori,S.
JOURNAL Unpublished (1988) see COMMENT for author address
STANDARD simple automatic
REFERENCE 2 (bases 1 to 1449)
AUTHORS Matuo,S., Tatsuno,M., Kobayashi,K., Saheki,T., Miyata,T.,
Takeyori,S., Iwanaga,S., Amaya,Y. and Mori,M.
TITLE Isolation of cDNA clones of human argininosuccinate lyase and
corrected amino acid sequence
JOURNAL FEBS Lett. 234, 395-399 (1988)
STANDARD simple automatic
COMMENT The sequence differs at nucleotide positions 1204, 1209, 1215, 1398
and 1402 from the one published by O'Brien et al., 1986 $<HHASL>$,
14218, causing a frameshift; aminoacid sequencing of liver ASL
supports [FEBS Lett. 234, 395-399 (1988)]. *source: tissue=liver;
clone=ASL 1-3, ASL 1-4, ASL
2-3;
[Unpublished (1988) see COMMENT for author address] Author address
Takeyori S., Dept. of Biochemistry, Faculty of
Medicine, Kagoshima University, Usuki-cho 1208-1, Kagoshima 890,
Japan.
Submitted (23-AUG-1988) to the EMBL data library.
FEATURES Location/Qualifiers
CDS 46..1440
/note="argininosuccinate lyase (AA 1 - 464)"
/codon_start=46
BASE COUNT 307 a 424 c 459 g 259 t
ORIGIN
1 cagacccgga gaccgaagct tccggacgac gaggaaccgc ccaacatggc ctcggagagt
61 gggaagcttt ggggtggccg gtttgtgggt gcagtggacc ccatcatgga gaagttcaac
121 gcgtccattg cctacgaccg gcacctttgg gaggtggatg ttcaaggcag caaagcctac
181 agcaggggcc tggagaaggc agggctcctc accaaggccg agatggacca gatactccat
241 ggcctagaca aggtggctga ggagtgggcc cagggcacct tcaaactgaa ctccaatgat
301 gaggacatcc acacagccaa tgagcgccgc ctgaaggagc tcattggtgc aacggcaggg
361 aagctgcaca cgggacggag ccggaatgac caggtggtca cagacctcag gctgtggatg
421 cggcagacct gctccacgct ctcgggcctc ctctgggagc tcattaggac catggtggat
481 cgggcagagg cggaacgtga tgttctcttc ccggggtaca cccatttgca gagggcccag
541 cccatccgct ggagccactg gattctgagc cacgccgtgg cactgacccg agactctgag
601 cggctgctgg aggtgcggaa gcggatcaat gtcctgcccc tggggagtgg ggccattgca
661 ggcaatcccc tgggtgtgga ccgagagctg ctccgagcag aactcaactt tggggccatc
721 actctcaaca gcatggatgc cactagtgag cgggactttg tggccgagtt cctgttctgg
781 cgttcgctgt gcatgaccca tctcagcagg atggccgagg acctcatcct ctactgcacc
841 aaggaattca gcttcgtgca gctctcagat gcctacagca cgggaagcag cctgatgccc
901 cagaagaaaa accccgacag tttggagctg atccggagca aggctgggcg tgtgtttggg
961 cggtgtgccg ggctcctgat gaccctcaag ggacttccca gcacctacaa caaagactta
1021 caggaggaca aggaagctgt gtttgaagtg tcagacacta tgagtgccgt gctccaggtg
1081 gccactggcg tcatctctac gctgcagatt caccaagaga acatgggaca ggctctcagc
1141 cccgacatgc tggccactga ccttgcctat tacctggtcc gcaaagggat gccattccgc
1201 caggcccatg aggcctccgg gaaagctgtg ttcatggccg agaccaaggg ggtcgccctc
1261 aaccagctgt cactgcagga gctgcagacc atcagccccc tgttctcggg cgacgtgatc
1321 tgcgtgtggg actaccggca cagtgtggag cagtatggtg ccctgggcgg cactgcgcgc
1381 tccagcgtcg actggcaaat ccgccaggtg cgggcgctac tgcaggcaca gcaggcctag
1441 gtcctccca
//