GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMATPAC2 1302 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human Na,K-ATPase alpha-1 subunit gene, exons 2 and 3.
ACCESSION M30310 J04754
KEYWORDS Na,K-ATPase alpha-1 subunit; sodium pump; transmembrane protein.
SEGMENT 2 of 2
SOURCE Human leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1302)
AUTHORS Lingrel,J.B.
JOURNAL Unpublished (1990) Dept.M.Gen., U of C., Cincinnati, OH 45267-0524
STANDARD full staff_review
REFERENCE 2 (sites)
AUTHORS Shull,M.M., Pugh,D.G. and Lingrel,J.B.
TITLE The human Na,K-ATPase alpha 1 gene: Characterization of the 5'-
flanking region and identification of restriction fragment length
polymorphisms
JOURNAL Genomics 6, 451-460 (1990)
STANDARD full staff_review
COMMENT
[Genomics 6, 451-460 (1990)] sites; for [Unpublished (1990)
Dept.M.Gen., U of C., Cincinnati, OH 45267-0524].
Draft entry and computer-readable sequence for [Genomics 6, 451-460
(1990)] kindly submitted
by J.B.Lingrel, 01-DEC-1989.
FEATURES Location/Qualifiers
prim_transcript <1..>1302
/note="ATP1A1 mRNA and introns"
intron <1..418
/note="ATP1A1 intron A"
CDS join(M30309:1018..1029,419..529,1188..1247)
/note="Na,K-ATPase alpha-1 subunit"
/codon_start=1018
exon 419..529
/partial
/note="Na,K-ATPase alpha-1 subunit, exon 2
/nomgen='ATP1A1' /map='1p13' /hgml_locus_uid='LK0041P' (EC
3.6.1.37)"
intron 530..1187
/note="ATP1A1 intron B"
exon 1188..>1247
/partial
/note="Na,K-ATPase alpha-1 subunit, exon 3"
intron 1248..>1302
/note="ATP1A1 intron C"
BASE COUNT 399 a 229 c 261 g 413 t
ORIGIN
1 ttgagaatgc ggactcataa gcacaatatt gcactctaag ttaataatgt aaagttagtt
61 tcattctttc agtagggaag atggaaggct gcagaatagg gattttgata gcaaaaatct
121 cctcattaac cccaaaagga agtggcactg cagggccatt ctgaagctac cggtagcttc
181 agtattgttc ttaatgctct tggatggaga gaatgtatct tgagccaatg tattaatagt
241 agattgcttt gcttatgtag taggcaatat atgggtatac atttttcctg actattatct
301 taatgactat tccaaattat gactacctta aaaactacca aaatcccctg ctccagaatt
361 ttcagtttca gatgaggttc ataattcatg gcctcacttt tcccacattc tcctacaggt
421 tggacgtgat aagtatgagc ctgcggctgt ttcagaacaa ggtgataaaa agggcaaaaa
481 gggcaaaaaa gacagggaca tggatgaact gaagaaagaa gtttctatgg taagtactag
541 gaggaatatt gtattccatc cttattaaaa atccatgatt tttaatcccc caggcctcac
601 tgtattcttc aaagaactgc tatatattaa aagagatcat agcagctgta cagatctcat
661 ctagtcgtag aggttaatgt tgaacatata ctttttaaaa gctgttagag ggtaggaaaa
721 gttattcagt cactctggca taaccagaga taacagaagg aacttaggtt gataccatga
781 gtctttgctt ttctctgtat tatatcaaac attgggaaat tcagcctctc caggcgatgg
841 aagcttccat agacttaacc tgtctagaat cgacctggtc atcagagaag gcagataagg
901 ttttactaga tccctgagag ctgctgggtt tctctgaagt gttatggcaa atagtaatgg
961 gccacggtca ctcagcttta gccattctcc agtgaagagc tgtcaatgat aactgtgtgg
1021 ttgcaaagcc acaaagcgat ggtgaaaatt gtaccaactt atgcactgaa gaaaacatct
1081 gcactttgtt taataagctt aatgatagta atgaataatg ctattttttc tgtcattttt
1141 ttatactaca ctgtttaact attttctttg tttctgtttt cccttaggat gatcataaac
1201 ttagccttga tgaacttcat cgtaaatatg gaacagactt gagccgggta tgttctagtt
1261 tgaaagctgt tgtacaaaac ctagttttcc gtattatatt tt
//