GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY201 920 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 1.
ACCESSION M18714 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 1 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 [Gene 28,
263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372 (1986)]
and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 543 to 910)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 920)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 543 to 910)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 920)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
exon 743..910
/note="alpha-amylase, exon 1 /nomgen='AMY2' /map='1p21'"
intron 911..>920
/note="alpha-amylase, intron A"
BASE COUNT 238 a 161 c 206 g 315 t
ORIGIN 194 bp upstream of XbaI site; chromosome 1p21.
1 gtattcaagg ttaactgtgc ccgttggtat ctgtacatat ctttgatttc agtctttact
61 acacgtggct tggtcacttc atggctaaaa acatgcttgt ggaagaccag tctggctcgg
121 tgagtctgtg cggccagcag tctctgatct gtacagggta ttaatgtgtc agggctgagt
181 gttctgggat ttgtctagag gctggtaagg gcttctggac cacttgtttc tgtcctgtca
241 gtctgtcagg gttggaaagt ccaagccata ggacccagtt tcctttctta gcttacgtta
301 tctaccagag caccgtgggc tgttacttac cttgagttgg aaggggttcg catttatacc
361 tgtaaaagta ttcatccttt taatttatgt aaagtttttt tgtatgccat tctggatctt
421 taaagagatg acaacaaatt ttggttttct actgttatgt gagaacatta ggccccagca
481 acaggtcact gtttaaggaa aaataaaagt gctgccagaa cctaagaaaa acattaatat
541 ctaaaaggtc atttagatga tttccatgag agactttttg atgttcttta cctgttagga
601 ttattattga taatcctttt cagattatga ataaacagtt tgccctcaag tatttattca
661 tgctaatatt tactttgtaa aatgtgcttc ttacaggaat ataaatagtt tctggaaagg
721 acactgacaa cttcaaagca aaatgaagtt ctttctgttg cttttcacca ttgggttctg
781 ctgggctcag tattccccaa atacacaaca aggacggaca tctattgttc atctgtttga
841 atggcgatgg gttgatattg ctcttgaatg tgagcgatat ttagctccga agggatttgg
901 aggggttcag gtgggtatga
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY202 167 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 2.
ACCESSION M18716 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 2 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 [Gene 28,
263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372 (1986)]
and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64 (1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 157)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 167)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 157)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 167)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron A"
exon 11..157
/note="alpha-amylase, exon 2 /nomgen='AMY2' /map='1p21'"
intron 158..>167
/note="alpha-amylase, intron B"
BASE COUNT 60 a 25 c 35 g 47 t
ORIGIN About 400 bp downstream of segment 1; chromosome 1p21.
1 taatttgtag gtctctccac caaatgaaaa tgttgcaatt tacaaccctt tcagaccttg
61 gtgggaaaga taccaaccag ttagctataa attatgcaca agatctggaa atgaagatga
121 atttagaaac atggtgacta gatgtaacaa tgttggggta agtgaat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY203 218 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 3.
ACCESSION M18718 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 3 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 208)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 218)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 208)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 218)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron B"
exon 11..208
/note="alpha-amylase, exon 3 /nomgen='AMY2' /map='1p21'"
intron 209..>218
/note="alpha-amylase, intron C"
BASE COUNT 61 a 32 c 55 g 70 t
ORIGIN About 800 bp downstream of segment 2; chromosome 1p21.
1 tgttttctag gttcgtattt atgtggatgc tgtaattaat catatgtgtg gtaacgctgt
61 gagtgcagga acaagcagta cctgtggaag ttacttcaac cctggaagta gggactttcc
121 agcagtccca tattctggat gggatttcaa tgatggtaaa tgtaaaactg gaagtggaga
181 tatcgagaac tacaatgatg ctactcaggt aatttttt
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY205 154 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 5.
ACCESSION M18722 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 5 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 144)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 154)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 144)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 154)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron D"
exon 11..144
/note="alpha-amylase, exon 5 /nomgen='AMY2' /map='1p21'"
intron 145..>154
/note="alpha-amylase, intron E"
BASE COUNT 50 a 21 c 40 g 43 t
ORIGIN About 800 bp downstream of segment 4; chromosome 1p21.
1 tttctactag gtaattgatc tgggtggtga gccaattaaa agcagtgact actttggtaa
61 tggccgggtg acagaattca agtatggtgc aaaactcggc acagttattc gcaagtggaa
121 tggagagaag atgtcttact taaagtaaat aaat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY206 143 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 6.
ACCESSION M18724 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 6 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 133)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 143)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 133)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 143)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron E"
exon 11..133
/note="alpha-amylase, exon 6 /nomgen='AMY2' /map='1p21'"
intron 134..>143
/note="alpha-amylase, intron F"
BASE COUNT 38 a 27 c 42 g 36 t
ORIGIN About 800 bp downstream of segment 5; chromosome 1p21.
1 tcaaaaatag gaactgggga gaaggttggg gtttcgtacc ttctgacaga gcgcttgtct
61 ttgtggataa ccatgacaat caacgaggac atggggctgg aggagcctct attcttacct
121 tctgggatgc taggtagaaa acc
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY207 120 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 7.
ACCESSION M18726 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 7 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 110)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 120)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 110)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 120)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron F"
exon 11..110
/note="alpha-amylase, exon 7 /nomgen='AMY2' /map='1p21'"
intron 111..>120
/note="alpha-amylase, intron G"
BASE COUNT 35 a 23 c 26 g 36 t
ORIGIN About 94 bp downstream of segment 6; chromosome 1p21.
1 taacttccag gctgtacaaa atggcagttg gatttatgct tgctcatcct tacggattta
61 cacgagtaat gtcaagctac cgttggccaa gacagtttca aaatggaaac gtaagttttg
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY208 139 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 8.
ACCESSION M18781 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 8 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 129)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 139)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 129)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 139)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron G"
exon 11..129
/note="alpha-amylase, exon 8 /nomgen='AMY2' /map='1p21'"
intron 130..>139
/note="alpha-amylase, intron H"
BASE COUNT 47 a 21 c 33 g 38 t
ORIGIN About 2000 bp downstream of segment 7; chromosome 1p21.
1 cctacttaag gatgttaatg attgggttgg gccaccaaat aataatggag taattaaaga
61 agttactatt aatccagaca ctacttgtgg caatgactgg gtctgtgaac atcgatggcg
121 ccaaataagg tgagaatat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY209 146 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 9.
ACCESSION M18783 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 9 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 136)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 146)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 136)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 146)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron H"
exon 11..136
/note="alpha-amylase, exon 9 /nomgen='AMY2' /map='1p21'"
intron 137..>146
/note="alpha-amylase, intron I"
BASE COUNT 43 a 18 c 39 g 46 t
ORIGIN About 111 bp downstream of segment 8; chromosome 1p21.
1 gtgtttttag gaacatggtt attttccgca atgtagtgga tggccagcct tttacaaatt
61 ggtatgataa tgggagcaac caagtggctt ttgggagagg aaacagagga ttcattgttt
121 tcaacaatga tgactggtaa gtaaat
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY210 250 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 10.
ACCESSION M18785 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 10 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 240)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 250)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 240)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 250)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron I"
CDS join(M18714:743..910,M18716:11..157,M18718:11..208,
M18720:11..241,M18722:11..144,M18724:11..133,
M18726:11..110,M18781:11..129,M18783:11..136,11..200)
/note="alpha-amylase"
/codon_start=743
exon 11..200
/note="alpha-amylase, exon 10 /nomgen='AMY2' /map='1p21'"
BASE COUNT 76 a 42 c 39 g 93 t
ORIGIN About 1300 bp downstream of segment 9; chromosome 1p21.
1 tattttacag gtcattttct ttaactttgc aaactggtct tcctgctggc acatactgtg
61 atgtcatttc tggagataaa attaatggca attgcacagg cattaaaatt tacgtttctg
121 atgatggcaa agctcatttt tctattagta actctgctga agatccattt attgcaattc
181 atgctgaatc taaattgtaa aatttaaaat taaatgcatg tcctcaaaac aatagccaag
241 tgtgtttctt
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMAMY204 251 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human pancreatic alpha-amylase (amy2) DNA, exon 4.
ACCESSION M18720 K02213
KEYWORDS alpha-amylase; amylase.
SEGMENT 4 of 10
SOURCE Human pancreas, cDNA to mRNA, clones pHPA76 and pHPA86 and [Gene
28, 263-270 (1984)],[Gene 41, 299-304 (1986)],[Gene 50, 371-372
(1986)] and Human cosmid library DNA, clone cosP2 [Gene 60, 57-64
(1987)].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 11 to 241)
AUTHORS Nakamura,Y., Ogawa,M., Nishide,T., Emi,M., Kosaki,G., Himeno,S. and
Matsubara,K.
TITLE Sequences of cDNAs for human salivary and pancreatic alpha-
amylases
JOURNAL Gene 28, 263-270 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 251)
AUTHORS Nishide,T., Nakamura,Y., Emi,M., Yamamoto,T., Ogawa,M., Takesada,M.
and Matsubara,K.
TITLE Primary structure of human salivary alpha-amylase gene
JOURNAL Gene 41, 299-304 (1986)
STANDARD full staff_review
REFERENCE 3 (bases 11 to 241)
AUTHORS Nishide,T., Emi,M., Nakamura,Y. and Matsubara,K.
TITLE Corrected sequences of cDNAs for human salivary and pancreatic
alpha-amylases
JOURNAL Gene 50, 371-372 (1986)
STANDARD full staff_review
REFERENCE 4 (bases 1 to 251)
AUTHORS Horii,A., Emi,M., Tomita,N., Nishide,T., Ogawa,M., Mori,T. and
Matsubara,K.
TITLE Primary structure of human pancreatic alpha-amylase gene: Its
comparison with human salivary alpha-amylase gene
JOURNAL Gene 60, 57-64 (1987)
STANDARD full staff_entry
COMMENT
[Gene 50, 371-372 (1986)] revises [Gene 28, 263-270 (1984)].
[Gene 60, 57-64 (1987)] revises [Gene 28, 263-270 (1984)],[Gene
41, 299-304 (1986)],[Gene 50, 371-372 (1986)].
Draft entry and computer readable copy of sequence [Gene 28,
263-270 (1984)] kindly
provided by A.Horii (14-MAR-1988).
[Gene 28, 263-270 (1984)] also sequenced the salivary alpha-amylase
mRNA. Comparison of
the two alpha-amylase nucleotide sequences reveals 96% homology in
the coding region. Comparison of the sequences of human
alpha-amylase cDNAs with those for mouse suggest the possibility of
gene conversion between the two genes of alpha-amylase.
FEATURES Location/Qualifiers
intron <1..10
/note="alpha-amylase, intron C"
exon 11..241
/note="alpha-amylase, exon 4 /nomgen='AMY2' /map='1p21'"
intron 242..>251
/note="alpha-amylase, intron D"
BASE COUNT 71 a 52 c 57 g 71 t
ORIGIN About 600 bp downstream of segment 3; chromosome 1p21.
1 acctcaacag gtcagagatt gtcgtctgac tggtcttctt gatcttgcac tggagaagga
61 ttacgtgcgt tctaagattg ccgaatatat gaaccatctc attgacattg gtgttgcagg
121 gttcagactt gatgcttcca agcacatgtg gcctggagac ataaaggcaa ttttggacaa
181 actgcataat ctaaacagta actggttccc tgcaggaagt aaacctttca tttaccagga
241 ggtacatcaa t
//