GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMCOLA1A1 1500 bp ss-mRNA PRI 08-MAY-1991
DEFINITION Human mRNA for alpha-1(I) chain of procollagen type I.
ACCESSION X07884
KEYWORDS COL1A1 gene; collagen.
SOURCE Human (Homo sapiens).
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1500)
AUTHORS Prockop,D.J.
JOURNAL Unpublished (1988) see COMMENT for author address
STANDARD simple automatic
REFERENCE 2 (sites)
AUTHORS Tromp,G., Kuivaniemi,H., Stacey,A., Shikata,H., Baldwin,C.T.,
Jaenisch,R. and Prockup,D.J.
TITLE Structure of a full length cDNA clone for the prepro alpha1(I)
chain of human type I procollagen
JOURNAL Biochem. J. 254, 919-922 (1988)
STANDARD full staff_review
COMMENT
[Unpublished (1988) see COMMENT for author address] for [Biochem.
J. 254, 919-922 (1988)].
[Biochem. J. 254, 919-922 (1988)] sites.
*source: tissue=fibroblast; cell line=SV80; library=lambda gt10;
*source: clone=pHUC1; **map: chromosomal location=17q21.31 - 22.05;
[Unpublished (1988) see COMMENT for author address] Author address
Prockop D.J., Department of Biochemistry and
Molecular Biology, Jefferson Institute of Molecular Medicine,
Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA
19107.
Submitted (13-JUN-1988) on tape to the EMBL data library.
FEATURES Location/Qualifiers
CDS 84..>1500
/note="preprocollagen (AA -22 to 450) (1500 is 1st base in
codon) /nomgen='COL1A1' /map='17q21.3'
/hgml_locus_uid='LG0047H'"
/codon_start=84
sig_peptide 84..149
/note="preprocollogen signal peptide (AA -22 to -1)"
/codon_start=84
mat_peptide 567..617
/note="telopeptide (AA 140 - 156)"
/codon_start=567
mat_peptide 618..>1500
/note="mature alpha-1(I) chain of collagen (AA 157 - 450)
(1500 is 1st base in codon)"
/codon_start=618
BASE COUNT 257 a 488 c 488 g 267 t
ORIGIN
1 ggcacgcgga gtgtgaggcc acgcatgagc ggacgctaac cccctcccca gccacaaaga
61 gtctacatgt ctagggtcta gacatgttca gctttgtgga cctccggctc ctgctcctct
121 tagcggccac cgccctcctg acgcacggcc aagaggaagg ccaagtcgag ggccaagacg
181 aagacatccc accaatcacc tgcgtacaga acggcctcag gtaccatgac cgagacgtgt
241 ggaaacccga gccctgccgg atctgcgtct gcgacaacgg caaggtgttg tgcgatgacg
301 tgatctgtga cgagaccaag aactgccccg gcgccgaagt ccccgagggc gagtgctgtc
361 ccgtctgccc cgacggctca gagtcaccca ccgaccaaga aaccaccggc gtcgagggac
421 ccaagggaga cactggcccc cgaggcccaa ggggacccgc aggcccccct ggccgagatg
481 gcatccctgg acagcctgga cttcccggac cccccggacc ccccggacct cccggacccc
541 ctggcctcgg aggaaacttt gctccccagc tgtcttatgg ctatgatgag aaatcaaccg
601 gaggaatttc cgtgcctggc cccatgggtc cctctggtcc tcgtggtctc cctggccccc
661 ctggtgcacc tggtccccaa ggcttccaag gtccccctgg tgagcctggc gagcctggag
721 cttcaggtcc catgggtccc cgaggtcccc caggtccccc tggaaagaat ggagatgatg
781 gggaagctgg aaaacctggt cgtcctggtg agcgtgggcc tcctgggcct cagggtgctc
841 gaggattgcc cggaacagct ggcctccctg gaatgaaggg acacagaggt ttcagtggtt
901 tggatggtgc caagggagat gctggtcctg ctggtcctaa gggtgagcct ggcagccctg
961 gtgaaaatgg agctcctggt cagatgggcc cccgtggcct gcctggtgag agaggtcgcc
1021 ctggagcccc tggccctgct ggtgctcgtg gaaatgatgg tgctactggt gctgccgggc
1081 cccctggtcc caccggcccc gctggtcctc ctggcttccc tggtgctgtt ggtgctaagg
1141 gtgaagctgg tccccaaggg ccccgaggct ctgaaggtcc ccagggtgtg cgtggtgagc
1201 ctggcccccc tggccctgct ggtgctgctg gccctgctgg aaaccctggt gctgatggac
1261 agcctggtgc taaaggtgcc aatggtgctc ctggtattgc tggtgctcct ggcttccctg
1321 gtgcccgagg cccctctgga ccccagggcc ccggcggccc tcctggtccc aagggtaaca
1381 gcggtgaacc tggtgctcct ggcagcaaag gagacactgg tgctaaggga gagcctggcc
1441 ctgttggtgt tcaaggaccc cctggccctg ctggagagga aggaaagcga ggagctcgag
//