GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMILA2R1A 1493 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human interleukin-2 receptor alpha (IL2R-alpha) gene, exon 1 and
promoter region.
ACCESSION M15864
KEYWORDS interleukin 2.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1493)
AUTHORS Cross,S.L., Feinberg,M.B., Wolf,J.B., Holbrook,N.J., Wong-Staal,F.
and Leonard,W.J.
TITLE Regulation of the human interleukin-2 receptor alpha chain
promoter: Activation of a nonfunctional promoter by the
transactivator gene of HTLV-1
JOURNAL Cell 49, 47-56 (1987)
STANDARD full staff_review
FEATURES Location/Qualifiers
mRNA 1185..>1493
/note="IL2R-a mRNA (alt.)"
mRNA 1243..>1493
/note="IL2R-a mRNA (alt.)"
CDS 1401..>1464
/partial
/note="interleukin-2 receptor alpha chain, exon 1
/nomgen='IL2R' /map='10p15-p14' /hgml_locus_uid='LE0105M'"
intron 1465..>1493
/note="IL2R-a intron A"
BASE COUNT 397 a 372 c 331 g 393 t
ORIGIN 5 bp upstream of PstI site; chromosome 10p15-p14.
1 ctgcagcctg cacctcctcg gttccagcta ttctcttgtc tcagcctcct gagtaactgg
61 gattacaggc gcccgccact acgcctggct aatttttgta tttttagtag aaatggggtt
121 ttaccatgtt ggccagactg gtctcaaact cccgacctca ggtgatctgc ctgcctcagc
181 ctcccaaagt gctggaatta caggcgtgtg ccactgcgcc tggctaattt tttttttttt
241 ttttttttag tagagacggt ggtttcacca tgtcatccag gctggtctca aactcctgac
301 ctcaggtgat ccacccacct tggtctacca aagtgctcgg attacaggca tgagccacca
361 ggcccagtca acgtgatgtg ttttggaacc ctgaattcct tggcttgccg gagggttttc
421 tttttgttaa tatctttgct tgctttctag tatttaaaaa attgtgtttt gctctaacta
481 tgcaatggct ttaagtctta gacaaatttc cagggagcaa aacacactca accaatttca
541 taataatcag aagagagctc tgatcaataa ataagcaaga ctgaatttta caaaataatc
601 caaagtttaa aaccaaagcc cactttttgc atgatccttt aagagaaaga aatctggaag
661 caaaacacct tataaaatga caatgcactt tcaggagccc agggcactgt ggtgaaatga
721 tgatggctag tacaggttat aagccttggg gaattattta tgaattctca ggatccttca
781 gttcgccgca tccttctcca ttatttgaat attggaggct gcctgaccag aatcttgtca
841 ggactttgct ccttcatccc aggtggtccc ggctgactcc tgaggacgtt acagccctga
901 ggggaggact cagcttatga agtgctgggt gagaccactg ccaagaagtg cttgctcacc
961 ctaccttcaa cggcagggga atctccctct ccttttatgg gcgtagtgaa gaaaggattc
1021 ataaatgaag ttcaatcctt ctcatcaacc ccagcccaca cctccagcaa ttgaacttga
1081 aaaaaaaaac ctggtttgaa aaattaccgc aaactatatg tcatcaaaaa aaaaaaaaaa
1141 aaaaacactt cctatatttg agatgagaga agagagtgct aggcagtttc ctggctgaac
1201 acgccagccc aatacttaaa gagagcaact cctgactccg atagagactg gatggaccca
1261 caagggtgac agcccaggcg gaccgatctt cccatcccac atcctccggc gcgatgccaa
1321 aaagaggctg acggcaactg ggccttctgc agagaaagac ctccgcttca ctgccccggc
1381 tggtcccaag ggtcaggaag atggattcat acctgctgat gtggggactg ctcacgttca
1441 tcatggtgcc tggctgccag gcaggtaagg gcctgtgggt gcccccggaa ttc
//