GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMLAMBB 5306 bp ss-mRNA PRI 08-MAY-1991
DEFINITION Human laminin B2 chain mRNA, complete cds.
ACCESSION J03202
KEYWORDS glycoprotein; laminin.
SOURCE Human placenta, cDNA to mRNA, clones HL-[205,209,210,220,237,246].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 5306)
AUTHORS Pikkarainen,T., Kallunki,T. and Tryggvason,K.
TITLE Human laminin B2 chain: Comparison of the complete amino acid
sequence with the B1 chain reveals variability in sequence homology
between different structural domains
JOURNAL J. Biol. Chem. 263, 6751-6758 (1988)
STANDARD full staff_entry
COMMENT Computer-readable copy of sequence for [J. Biol. Chem. 263,
6751-6758 (1988)] kindly provided by
K.Tryggvason, 26-FEB-1988.
FEATURES Location/Qualifiers
mRNA <1..5306
/note="LAMB2 mRNA"
CDS 260..5089
/note="laminin B2 precursor /nomgen='LAMB2' /map='1q31'
/hgml_locus_uid='LE0061G'"
sig_peptide 260..358
/note="laminin B2 signal peptide (3' end put.)"
mat_peptide 359..5086
/note="laminin B2 (5' end put.)"
BASE COUNT 1387 a 1310 c 1490 g 1119 t
ORIGIN 681 bp upstream of HindIII site; chromosome 1q31.
1 cggggcaggc tgctcccggg gtaggtgagg gaagcgcgga ggcggcgcgc gggggcagtg
61 gtcggcgagc agcgcggtcc tcgctagggg cgcccacccg tcagtctctc cggcgcgagc
121 cgccgccacc gcccgcgccg gagtcaggcc cctgggcccc caggctcaag cagcgaagcg
181 gcctccgggg gacgccgcta ggcgagagga acgcgccggt gcccttgcct tcgccgtgac
241 ccagcgtgcg ggcggcggga tgagagggag ccatcgggcc gcgccggccc tgcggccccg
301 ggggcggctc tggcccgtgc tggccgtgct ggcggcggcc gccgcggcgg gctgtgccca
361 ggcagccatg gacgagtgca cggacgaggg cgggcggccg cagcgctgca tgcccgagtt
421 cgtcaacgcc gctttcaacg tgactgtggt ggccaccaac acgtgtggga ctccgcccga
481 ggaatactgt gtgcagaccg gggtgaccgg ggtcaccaag tcctgtcacc tgtgcgacgc
541 cgggcagccc cacctgcagc acggggcagc cttcctgacc gactacaaca accaggccga
601 caccacctgg tggcaaagcc agaccatgct ggccggggtg cagtacccca gctccatcaa
661 cctcacgctg cacctgggaa aagcttttga catcacctat gtgcgtctca agttccacac
721 cagccgcccg gagagctttg ccatttacaa gcgcacacgg gaagacgggc cctggattcc
781 ttaccagtac tacagtggtt cctgcgagaa cacctactcc aaggcaaacc gcggcttcat
841 caggacagga ggggacgagc agcaggcctt gtgtactgat gaattcagtg acatttctcc
901 cctcactggg ggcaacgtgg ccttttctac cctggaagga aggcccagcg cctataactt
961 tgacaatagc cctgtgctgc aggaatgggt aactgccact gacatcagag taactcttaa
1021 tcgcctgaac acttttggag atgaagtgtt taacgatccc aaagttctca agtcctatta
1081 ttatgccatc tctgattttg ctgtaggtgg cagatgtaaa tgtaatggac acgcaagcga
1141 gtgtatgaag aacgaatttg ataagctggt gtgtaattgc aaacataaca catatggagt
1201 agactgtgaa aagtgtcttc ctttcttcaa tgaccggccg tggaggaggg caactgcgga
1261 aagtgccagt gaatgcctgc cctgtgattg caatggtcga tcccaggaat gctacttcga
1321 ccctgaactc tatcgttcca ctggccatgg gggccactgt accaactgcc aggataacac
1381 agatggcgcc cactgtgaga ggtgccgaga gaacttcttc cgccttggca acaatgaagc
1441 ctgctcttca tgccactgta gtcctgtggg ctctctaagc acacagtgtg atagttacgg
1501 cagatgcagc tgtaagccag gagtgatggg ggacaaatgt gaccgttgcc agcctggatt
1561 ccattctctc actgaagcag gatgcaggcc atgctcttgt gatccctctg gcagcataga
1621 tgaatgtaat gttgaaacag gaagatgtgt ttgcaaagac aatgtcgaag gcttcaattg
1681 tgaaagatgc aaacctggat tttttaatct ggaatcatct aatcctcggg gttgcacacc
1741 ctgcttctgc tttgggcatt cttctgtctg tacaaacgct gttggctaca gtgtttattc
1801 tatctcctct acctttcaga ttgatgagga tgggtggcgt gcggaacaga gagatggctc
1861 tgaagcatct ctcgagtggt cctctgagag gcaagatatc gccgtgatct cagacagcta
1921 ctttcctcgg tacttcattg ctcctgcaaa gttcttgggc aagcaggtgt tgagttatgg
1981 tcagaacctc tccttctcct ttcgagtgga caggcgagat actcgcctct ctgccgaaga
2041 ccttgtgctt gagggagctg gcttaagagt atctgtaccc ttgatcgctc agggcaattc
2101 ctatccaagt gagaccactg tgaagtatgt cttcaggctc catgaagcaa cagattaccc
2161 ttggaggcct gctcttaccc cttttgaatt tcagaagctc ctaaacaact tgacctctat
2221 caagatacgt gggacataca gtgagagaag tgctggatat ttggatgatg tcaccctggc
2281 aagtgctcgt cctgggcctg gagtccctgc aacttgggtg gagtcctgca cctgtcctgt
2341 gggatatgga gggcagtttt gtgagatgtg cctctcaggt tacagaagag aaactcctaa
2401 tcttggacca tacagtccat gtgtgctttg cgcctgcaat ggacacagcg agacctgtga
2461 tcctgagaca ggtgtttgta actgcagaga caatacggct ggcccgcact gtgagaagtg
2521 cagtgatggg tactatggag attcaactgc aggcacctcc tccgattgcc aaccctgtcc
2581 gtgtcctgga ggttcaagtt gtgctgttgt tcccaagaca aaggaggtgg tgtgcaccaa
2641 ctgtcctact ggcaccactg gtaagagatg tgagctctgt gatgatggct actttggaga
2701 ccccctgggt agaaacggcc ctgtgagact ttgccgcctg tgccagtgca gtgacaacat
2761 cgatcccaac gcagttggaa attgcaatcg cttgacggga gaatgcctga agtgcatcta
2821 taacactgct ggcttctatt gtgaccggtg caaagacgga ttttttggaa atcccctggc
2881 tcccaatcca gcagacaaat gcaaagcctg caattgcaat ccgtatggga ccatgaagca
2941 gcagagcagc tgtaaccccg tgacggggca gtgtgaatgt ttgcctcacg tgactggcca
3001 ggactgtggt gcttgtgacc ctggattcta caatctgcag agtgggcaag gctgtgagag
3061 gtgtgactgc catgccttgg gctccaccaa tgggcagtgt gacatccgca ccggccagtg
3121 tgagtgccag cccggcatca ctggtcagca ctgtgagcgc tgtgaggtca accactttgg
3181 gtttggacct gaaggctgca aaccctgtga ctgtcatcct gagggatctc tttcacttca
3241 gtgcaaagat gatggtcgct gtgaatgcag agaaggcttt gtgggaaatc gctgtgacca
3301 gtgtgaagaa aactatttct acaatcggtc ttggcctggc tgccaggaat gtccagcttg
3361 ttaccggctg gtaaaggata aggttgctga tcatagagtg aagctccagg aattagagag
3421 tctcatagca aaccttggaa ctggggatga gatggtgaca gatcaagcct tcgaggatag
3481 actaaaggaa gcagagaggg aagttatgga cctccttcgt gaggcccagg atgtcaaaga
3541 tgttgaccag aatttgatgg atcgcctaca gagagtgaat aacactctgt ccagccaaat
3601 tagccgttta cagaatatcc ggaataccat tgaagagact ggaaacttgg ctgaacaagc
3661 gcgtgcccat gtagagaaca cagagcggtt gattgaaatc gcatccagag aacttgagaa
3721 agcaaaagtc gctgctgcca atgtgtcagt cactcagcca gaatctacag gggacccaaa
3781 caacatgact cttttggcag aagaggctcg aaagcttgct gaacgtcata aacaggaagc
3841 tgatgacatt gttcgagtgg caaagacagc caatgatacg tcaactgagg catacaacct
3901 gcttctgagg acactggcag gagaaaatca aacagcattt gagattgaag agcttaatag
3961 gaagtatgaa caagcgaaga acatctcaca ggatctggaa aaacaagctg cccgagtaca
4021 tgaggaggcc aaaagggccg gtgacaaagc tgtggagatc tatgccagcg tggctcagct
4081 gagccctttg gactctgaga cactggagaa tgaagcaaat aacataaaga tggaagctga
4141 gaatctggaa caactgattg accagaaatt aaaagattat gaggacctca gagaagatat
4201 gagagggaag gaacttgaag tcaagaacct tctggagaaa ggcaagactg aacagcagac
4261 cgcagaccaa ctcctagccc gagctgatgc tgccaaggcc ctcgctgaag aagctgcaaa
4321 gaagggacgg gataccttac aagaagctaa tgacattctc aacaacctga aagattttga
4381 taggcgcgtg aacgataaca agacggccgc agaggaggca ctaaggaaga ttcctgccat
4441 caaccagacc atcactgaag ccaatgaaaa gaccagagaa gcccagcagg ccctgggcag
4501 tgctgcggcg gatgccacag aggccaagaa caaggcccat gaggcggaga ggatcgcaag
4561 cgctgtccaa aagaatgcca ccagcaccaa ggcagaagct gaaagaactt ttgcagaagt
4621 tacagatctg gataatgagg tgaacaatat gttgaagcaa ctgcaggaag cagaaaaaga
4681 gctaaagaga aaacaagatg acgctgacca ggacatgatg atggcaggga tggcttcaca
4741 ggctgctcaa gaagccgaga tcaatgccag aaaagccaaa aactctgtta ctagcctcct
4801 cagcattatt aatgacctct tggagcagct ggggcagctg gatacagtgg acctgaataa
4861 gctaaacgag attgaaggca ccctaaacaa agccaaagat gaaatgaagg tcagcgatct
4921 tgataggaaa gtgtctgacc tggagaatga agccaagaag caggaggctg ccatcatgga
4981 ctataaccga gatatcgagg agatcatgaa ggacattcgc aatctggagg acatcaggaa
5041 gaccttacca tctggctgct tcaacacccc gtccattgaa aagccctagt gtctttaggg
5101 ctggaaggca gcatccctct gacagggggg cagttgtgag gccacagagt gccttgacac
5161 aaagattaca tttttcagac ccccactcct ctgctgctgt ccatcactgt ccttttgaac
5221 caggaaaagt cacagagttt aaagagaagc aaattaaaca tcctgaatcg ggaacaaagg
5281 gttttatcta ataaagtgtc tcttcc
//