GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMMHBA17W 3520 bp ds-DNA PRI 08-MAY-1991
DEFINITION Human MHC class I HLA-Bw58 gene, complete cds.
ACCESSION M11799
KEYWORDS cell surface antigen; cell surface glycoprotein; class I gene;
integral membrane protein; major histocompatibility complex.
SOURCE Human B lymphoblastoid cell line WT49 DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3520)
AUTHORS Ways,J.P., Coppin,H.L. and Parham,P.
TITLE The complete primary structure of HLA-Bw58
JOURNAL J. Biol. Chem. 260, 11924-11933 (1985)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS join(88..160,290..559,806..1081,1657..1932,2037..2153,
2595..2627,2734..2777)
/note="HLA-Bw58 of MHC"
prim_transcript 67..3386
/note="HLA-Bw58 of MHC, mRNA and introns"
exon 88..160
/note="HLA-Bw58 of MHC, exon 1 /nomgen='HLA-B'
/map='6p21.3' /hgml_locus_uid='LL0111R'"
intron 161..289
/note="HLA-Bw58 intron A"
exon 290..559
/note="HLA-Bw58 of MHC, exon 2"
intron 560..805
/note="HLA-Bw58 intron B"
exon 806..1081
/note="HLA-Bw58 of MHC, exon 3"
intron 1082..1656
/note="HLA-Bw58 intron C"
exon 1657..1932
/note="HLA-Bw58 of MHC, exon 4"
intron 1933..2036
/note="HLA-Bw58 intron D"
exon 2037..2153
/note="HLA-Bw58 of MHC, exon 5"
intron 2154..2594
/note="HLA-Bw58 intron E"
exon 2595..2627
/note="HLA-Bw58 of MHC, exon 6"
intron 2628..2733
/note="HLA-Bw58 intron F"
exon 2734..2777
/note="HLA-Bw58 of MHC, exon 7"
BASE COUNT 665 a 981 c 1099 g 775 t
ORIGIN Chromosome 6p21.3.
1 tctagagaag ccaatcagtg tcgccggggt cccagttcta aagtccccac gcacccaccc
61 ggactcagaa tctcctcaga cgccgagatg cgggtcacgg cgccccgaac cgtcctcctg
121 ctgctctggg gggcagtggc cctgaccgag acctgggccg gtgagtgcgg ggtcgggagg
181 gaaatggcct ctgtggggag gagcgagggg accgcaggcg ggggcgcagg acctgaggag
241 ccgcgccggg aggagggtcg ggcgggtctc agcccctcct cgcccccagg ctcccactcc
301 atgaggtatt tctacaccgc catgtcccgg cccggccgcg gggagccccg cttcatcgca
361 gtgggctacg tggacgacac ccagttcgtg aggttcgaca gcgacgccgc gagtccgagg
421 acggagcccc gggcgccatg gatagagcag gaggggccgg agtattggga cggggagaca
481 cggaacatga aggcctccgc gcagacttac cgagagaacc tgcggatcgc gctccgctac
541 tacaaccaga gcgaggccgg tgagtgaccc cggcccgggg cgcaggtcac gactccccat
601 cccccacgta cggcccgggg tcgccccgag tctccgggtc cgagatccgc ctccctgagg
661 ccgcgggacc cgcccagacc ctcgaccggc gagagcccca ggcgcgttta cccggtttca
721 ttttcagttg aggccaaaat ccccgcgggt tggtcggggc ggggcggggc tcgggggacg
781 gggctgaccg cggggccggg gccagggtct cacatcatcc agaggatgta tggctgcgac
841 ctggggcccg acgggcgcct cctccgcggg catgaccagt ccgcctacga cggcaaggat
901 tacatcgccc tgaacgagga cctgagctcc tggaccgcgg cggacaccgc ggctcagatc
961 acccagcgca agtgggaggc ggcccgtgtg gcggagcagc tgagagccta cctggagggc
1021 ctgtgcgtgg agtggctccg cagatacctg gagaacggga aggagacgct gcagcgcgcg
1081 ggtaccaggg gcagtgggga gccttcccca tctcctatag gtcgccgggg atggcctccc
1141 acgagaagag gaggaaaatg ggatcagcgc tagaatgtcg ccctcccttg aatggagaat
1201 ggcatgagtt ttcctgagtt tcctctgagg gccccctctt ctctctagga caattaaggg
1261 atgacgtctc tgaggaaatg gaggggaaga cagtccctag aatactgatc aggggtcccc
1321 tttgacccct gcagcagcct tgggaaccgt gacttttcct ctcaggcctt gttctctgcc
1381 tcacactcag tgtgtttggg gctctgattc cagcacttct gagtcacttt acctccactc
1441 agatcaggag cagaagtccc tgttccccgc tcagagactc gaactttcca atgaatagga
1501 gattatccca ggtgcctgcg tccaggctgg tgtctgggtt ctgtgcccct tccccacacc
1561 aggtgtcctg tccattctca ggctggtcac atgggtggtc ctagggtgtc ccatgagaga
1621 tgcaaagcgc ctgaattttc tgactcttcc catcagaccc cccaaagaca cacgtgaccc
1681 accaccccgt ctctgaccat gaggccaccc tgaggtgctg ggccctgggc ttctaccctg
1741 cggagatcac actgacctgg cagcgggatg gcgaggacca aactcaggac actgagcttg
1801 tggagaccag accagcagga gatagaacct tccagaagtg ggcagctgtg gtggtgcctt
1861 ctggagaaga gcagagatac acatgccatg tacagcatga ggggctgccg aagcccctca
1921 ccctgagatg gggtaaggag ggggatgagg ggtcatatct cttctcaggg aaagcaggag
1981 cccttctgga gcccttcagc agggtcaggg cccctcgtct tcccctcctt tcccagagcc
2041 atcttcccag tccaccatcc ccatcgtggg cattgttgct ggcctggctg tcctagcagt
2101 tgtggtcatc ggagctgtgg tcgctactgt gatgtgtagg aggaagagct caggtaggga
2161 aggggtgagg ggtggggtct gggttttctt gtcccactgg gggtttcaag ccccaggtag
2221 aagtgttccc tccctcatta ctgggaagca gcatccacac aggggctaac gcagcctggg
2281 accctgtgtg ccagcactta ctcttttgtg cagcacatgt gacaatgaag gacggatgta
2341 tcaccttgat ggttgtggtg ttggggtcct gatttcagca ttcatgagtc aggggaaggt
2401 ccctgctaag gacagacctt aggagggcag ttggtccagg acccacactt gctttcctcg
2461 tgtttcctga tcctgccttg ggtctgtagt catacttctg gaaattcctt ttgggtccaa
2521 gacgaggagg ttcctctaag atcttaaggc cctgcttcct cccagtcccc tcacaggaca
2581 ttttcttccc acaggtggaa aaggagggag ctactctcag gctgcgtgta agtggtgggg
2641 gtgggagtgt ggaggagctc acccacccca taattcctcc tgtcccacgt ctcctgcggg
2701 ctctgaccag gtcctgtttt tgttctactc cagccagcga cagtgcccag ggctctgatg
2761 tgtctctcac agcttgaaaa ggtgagattc ttggggtcta gagtgggtcg ggtggcgggt
2821 ctgggggtgg gtggggcaga ggggaaaggc ctgggtaatg gggattcttt gattgggatg
2881 tttcgcgtgt gtggtgggct gtttacagtg tcatcgctta ccatgactaa ccagaatttg
2941 ttcatgactg ttgttttctg tagcctgaga cagctgtctt gtgagggact gagatgcagg
3001 atttcttcac gcctcccctt tgtgacttca agagcctctg gcatctcttt ctgcaaaggc
3061 acctgaatgt gtctgcgtcc ctgttagcat aatgtgagga ggtggagaca cagcccaccc
3121 ttgtgtccac tgtgacccct gttcccatgc tgacctgtgt ttcctcccca gtcatctttc
3181 ctgttccaga gaggtggggc tggatgtctc catctctgtc tcaactttac gtgcactgag
3241 ctgcaacttc ttacttccct actgaaaata agaatctgaa tataaatttg ttttctcaaa
3301 tatttgctat gagaggttga tggattaatt aaataagtca attcctggaa tttgagagag
3361 caaataaaga cctgagaacc ttccagaatc tgcatgttcg ctgtgctgag tctgttgcag
3421 gtggggtgtg gagaaggctg tggggggccg agtgtggacg gggcctgtgc ccatttggtg
3481 ttgagtccat catgggcttt atgtggttag tcctcagctg
//