GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS HUMMHDRA1A 694 bp ss-mRNA PRI 08-MAY-1991
DEFINITION Human MHC class II HLA-DR1 beta mRNA (DR1,DQw1,Dw), 3' end.
ACCESSION M21008
KEYWORDS cell surface glycoprotein; class II gene;
integral membrane protein; major histocompatibility complex.
SOURCE Human (American black haplotype DR1,DQw1,Dw) B lymphocyte cell line
B-LCL 1568 DNA, clone 69.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 694)
AUTHORS Hurley,C.K., Ziff,B.L., Silver,J., Gregersen,P.K., Hartzman,R. and
Johnson,A.H.
TITLE Polymorphism of the HLA-DR1 haplotype in American blacks:
Identification of a DR1 beta-chain determinant recognized in the
mixed lymphocyte reaction
JOURNAL J. Immunol. 140, 4019-4023 (1988)
STANDARD simple staff_review
COMMENT Draft entry and printed copy of sequence for [J. Immunol. 140,
4019-4023 (1988)] kindly provided by
C.Hurley, 30-NOV-1989.
FEATURES Location/Qualifiers
CDS <1..694
/note="MHC HLA-DR1-beta /nomgen='HLA-DRB1' /map='6p21.3'
/hgml_locus_uid='LV0063D'"
BASE COUNT 153 a 168 c 231 g 142 t
ORIGIN Chromosome 6p21.3.
1 cttgtggcag cttaagtttg aatgtcattt cttcaatggg acggagcggg tgcggttgct
61 ggaaagatgc atctataacc aagaggagtc cgtgcgcttc gacagcgacg tgggggagta
121 ccgggcggtg acggagctgg ggcggcctga tgccgagtac tggaacagcc agaaggacct
181 cctggagcag aggcgggccg cggtggacac ctattgcaga cacaactacg gggctgtgga
241 gagcttcaca gtgcagcggc gagttgagcc taaggtgact gtgtatcctt caaagaccca
301 gcccctgcag caccacaacc tcctggtctg ctctgtgagt ggtttctatc caggcagcat
361 tgaagtcagg tggttccgga acggccagga agagaaggct ggggtggtgt ccacaggcct
421 gatccagaat ggagattgga ccttccagac cctggtgatg ctggaaacag ttcctcggag
481 tggagaggtt tacacctgcc aagtggagca cccaagtgtg acgagccctc tcacagtgga
541 atggagagca cggtctgaat ctgcacagag caagatgctg agtggagtcg ggggcttcgt
601 gctgggcctg ctcttccttg gggccgggct gttcatctac ttcaggaatg agaaaggaca
661 ctctggactt cagccaacag gattcctgag ctga
//