GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS RABACE 583 bp ds-DNA MAM 29-MAR-1991
DEFINITION Rabbit angiotensin-converting enzyme (ACE-P) gene, 5' end.
ACCESSION M58579
KEYWORDS angiotensin-converting enzyme.
SOURCE Rabbit (strain New Zealand white) DNA.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 583)
AUTHORS Kumar,R.S., Thekkumkara,T.J. and Sen,G.C.
TITLE The mRNAs encoding the two angiotensin-converting isozymes are
transcribed from the same gene by a tissue-specific choice of
alternative transcription initiation sites
JOURNAL J. Biol. Chem. 266, 3854-3862 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
TATA_signal 267..271
/gene="ACE"
mRNA 293..584
/product="angiotensin-converting enzyme"
/gene="ACE"
/partial
CDS 319..584
/EC_number="3.4.15.1"
/product="angiotensin-converting enzyme"
/gene="ACE"
/codon_start=319
/partial
sig_peptide 319..384
/gene="ACE"
/codon_start=319
mat_peptide 385..583
/EC_number="3.4.15.1"
/product="angiotensin-converting enzyme"
/gene="ACE"
/codon_start=385
/partial
BASE COUNT 66 a 224 c 227 g 66 t
ORIGIN
1 cagccccatc ggccggccgc gctagcggtc ctcgaccgac tcccctgccc gcctggtctc
61 tccgcacccg cgcaggcctg gggagcttag gccgggcaca ggaggaaggg gcggctgcgc
121 tcccccgggg gagtctgacc cggccccacc ccggcccgcg cccccgcccg ctcggtgcgg
181 ccggcgcggc cggggacttt ggagccgcgg aggaagcgct ttggggcggg gagctggggg
241 tgtgtcggaa ggcggcggcg cggttttata atccgcaggg cggccgcggc cggaggaggc
301 agcgccgcgc accacgccat gggggccgcg ccgggccgcc gggggccgag gctgctgcgg
361 ccgccgccgc cctgctgctg ctgctcctgc tgctgcggcc ggccgcccgc cgccctgacg
421 ctggaccctg ggctgctgcc cggcgacttt gccgccgacg aggccggcgc gcggctcttc
481 gcgagcagct acaactcgag cgccgagcag gtgctgtttc ggagcaccgc agccagctgg
541 gcgcacgaca ccaacatcac cgcggagaac gcaaggcgcc agg
//GenBank-Updates@genbank.bio.net (03/29/91)
LOCUS RABACE1 1149 bp ds-DNA MAM 29-MAR-1991
DEFINITION Rabbit angiotensin-converting enzyme (ACE) gene, 5' end.
ACCESSION M58580
KEYWORDS angiotensin-converting enzyme.
SOURCE Rabbit (strain White New Zealand) liver DNA.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 1149)
AUTHORS Kumar,R.S., Thekkumkara,T.J. and Sen,G.C.
TITLE The mRNAs encoding the two angiotensin-converting isozymes are
transcribed from the same gene by a tissue-specific choice of
alternative transcription initiation sites
JOURNAL J. Biol. Chem. 266, 3854-3862 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS join(651..864,1013..1149)
/EC_number="3.4.15.1"
/product="angiotensin-converting enzyme"
/gene="ACE"
/codon_start=651
/partial
mRNA join(217..430,631..864,1013..1149)
/product="angiotensin-converting enzyme"
/gene="ACE"
/partial
exon 217..430
/number=1
/gene="ACE"
intron 431..630
/number=1
/gene="ACE"
exon 631..864
/number=2
/note="testis-specific exon"
/gene="ACE"
intron 865..1012
/number=2
/gene="ACE"
BASE COUNT 218 a 370 c 378 g 183 t
ORIGIN
1 ggggctgact gatgtagcca ccttcctctc ctctctccct gtccatactc ttccttggtc
61 aaatgcttgt tgaggctggc atggggcaac aactgtcccc tgtcacctgt gcaagatcct
121 aagccctgag tctgactgtc gccttcttgg gcagaagtgc tagggggcag ctggggacag
181 tggcgacccc tgagccccgg cgcccgctgt ggccaacagg cggtgctgca ggcaggctgc
241 tccaggccct ggcaggaggt gctcaaggac atggtcgcct ccgacgccct ggacgcccag
301 ccgctgctcg actacttcca gccagtcacc cagtggctgc aggagcagaa cgagcgcaat
361 ggcgaggtcc tgggctggcc ggagtatcag tggcgcccac cgctgcccaa caactacccg
421 gaaggcatcg gtaaagcccc aagcgagggg agcccaggcc ccaggttccc agtcagctcc
481 ccccagccga gccctggcag cctgcggcag ggctgggccg tggatggtgc atcctggtga
541 gggcccccag gggcaggctg gccaggcaca ctgctctatg aggtcacact gcaggctctg
601 ctcttattgg ccagggttca ctggctgcag ggctctactc tccggcggcc atgggccaag
661 gttgggctgc tccaggactg cccagcctcc tcctcctgct gctttgctgc gggcactccc
721 tgctggtccc cagccgggtg gctgcccgcc gggtaacagt caaccagggg acaaccagcc
781 aggcaacaac caccagcaag gcgacaacca gcatccgggc aaccacccac cagacaacag
841 cccaccagac aactcagagc ccaagtggga gcttggagag gggcagggct ggggtgggct
901 gatggtggga gaggccgggg cggcaggcag gggaaggagg gaggctcccg tgagacccag
961 gctggggagg gcaaggggag acacctctgt tgccctccac tctgtcccat agacctggtg
1021 accgatgagg ctgaggccag ccggttcgtg gaggagtatg accggtcgtt ccaggcagtg
1081 tggaatgagt acgcggaggc caactggaac tataacacca acatcaccac agaggccagc
1141 aagatcctg
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS RABACE 583 bp ds-DNA MAM 08-MAY-1991
DEFINITION Rabbit angiotensin-converting enzyme (ACE-P) gene, 5' end.
ACCESSION M58579
KEYWORDS angiotensin-converting enzyme.
SOURCE Rabbit (strain New Zealand white) DNA.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 583)
AUTHORS Kumar,R.S., Thekkumkara,T.J. and Sen,G.C.
TITLE The mRNAs encoding the two angiotensin-converting isozymes are
transcribed from the same gene by a tissue-specific choice of
alternative transcription initiation sites
JOURNAL J. Biol. Chem. 266, 3854-3862 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
TATA_signal 267..271
/gene="ACE"
mRNA 293..583
/product="angiotensin-converting enzyme"
/gene="ACE"
/partial
CDS 319..583
/EC_number="3.4.15.1"
/product="angiotensin-converting enzyme"
/gene="ACE"
/codon_start=319
/partial
sig_peptide 319..384
/gene="ACE"
/codon_start=319
mat_peptide 385..583
/EC_number="3.4.15.1"
/product="angiotensin-converting enzyme"
/gene="ACE"
/codon_start=385
/partial
BASE COUNT 66 a 224 c 227 g 66 t
ORIGIN
1 cagccccatc ggccggccgc gctagcggtc ctcgaccgac tcccctgccc gcctggtctc
61 tccgcacccg cgcaggcctg gggagcttag gccgggcaca ggaggaaggg gcggctgcgc
121 tcccccgggg gagtctgacc cggccccacc ccggcccgcg cccccgcccg ctcggtgcgg
181 ccggcgcggc cggggacttt ggagccgcgg aggaagcgct ttggggcggg gagctggggg
241 tgtgtcggaa ggcggcggcg cggttttata atccgcaggg cggccgcggc cggaggaggc
301 agcgccgcgc accacgccat gggggccgcg ccgggccgcc gggggccgag gctgctgcgg
361 ccgccgccgc cctgctgctg ctgctcctgc tgctgcggcc ggccgcccgc cgccctgacg
421 ctggaccctg ggctgctgcc cggcgacttt gccgccgacg aggccggcgc gcggctcttc
481 gcgagcagct acaactcgag cgccgagcag gtgctgtttc ggagcaccgc agccagctgg
541 gcgcacgaca ccaacatcac cgcggagaac gcaaggcgcc agg
//