GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS MUSCSIS01 3393 bp ds-DNA ROD 08-MAY-1991
DEFINITION Mouse platelet-derived growth factor B chain (c-sis) gene, exon 1.
ACCESSION M64844 M55394
KEYWORDS c-sis proto-oncogene; platelet-derived growth factor;
platelet-derived growth factor B chain; proto-oncogene.
SEGMENT 1 of 6
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 3393)
AUTHORS Bonthron,D.T., Sultan,P. and Collins,T.
TITLE Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding
the B chain of platelet-derived growth factor
JOURNAL Genomics 10, 287-292 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
TATA_signal 2041..2045
exon 2070..3108
/number=1
/gene="c-sis"
BASE COUNT 663 a 972 c 1010 g 748 t
ORIGIN
1 gaattccagc aactcacata atttaatttt tctttatggc tgagaaaagt ccaccgtgtg
61 tatacagtgc atttcctcta tctgttcctg tgtggatgga tacccaggtt agatctagtc
121 caagttgctc agtccctatg tgggccagtc tccacggtgg taagataaaa taacaacata
181 tcttatagaa gctctgcagg gacgcagggt cagctcattg gtggctctac cactgtactt
241 acagataagg atatcgggca agagcaaggc caagttcacc cagctgtctg gaggaagtac
301 ttttaaatat ctaagtcttc tgacacgggg gtcaagtgtg ttgaattatt tccacccaaa
361 cagggctatc tgtcatcttg tctcaacata tctgtctgtc ctggatgatg gtcctaggga
421 ggagtctctt ttgtatgctt cctgccactc tgtgaggagg gcaaacccct ttcactgcat
481 caaggtactg cacgtatcag tttaaaacca agttcatgta tatgtgtgtg gtgtgtgtgc
541 atgcctgcgc gtgtgttcag gtgactggaa aacctccagt gtcaccctta gaaacactgt
601 caatgtcttt tgagatagtg tctctcattg gcctgaagct cacagattgg tctagactgt
661 ctgggcgggc ggcaagtgct agtctctacc ttcccgatgc ctgtttagat gagttctggg
721 actggactca gctcctcttc taagcatttt accaaatggg ggtctcccca gacccccaac
781 ccaacctatg gagcccactg tcacagagat ggcaaacatt gccagccccc tctcattttc
841 ccacgatcct ctgcaattct tcttctcctc cggttatgtc tccgagttac agaagaggaa
901 atcaaggtac cattggtgag cttaacctac cttagaggtc acctgctcca ggctacctcc
961 cagccactct gctagctagt catttggaaa aatggggtac ctggagccac gtgtaaagag
1021 gcccgagagg ttcttcctta tcagtaccac ctcatccagg gccatgagag gcaacagcac
1081 cattcagtgg atatggggat acagaccaag tggagatgac aggcagcaga agtggatgag
1141 ggcaaggtgc cctaaaggca ggaggcattg cagtgagcct gccggtcttg tggtgggtgc
1201 tgggctggca agcgtgcttg cgtgtgactg tgtcactgtg acagtgtgac tgctgaaggc
1261 agggacacag cagttccctg agctgggggt ggaaggcgtt aactgtgaga gtgctggtgt
1321 gggtgggtag cctctgggcc tggaactggg tggggggcag agaggggtag taaacaccct
1381 ggtgacttga cggcagcatc ttggtggcag cccttgggag gatggtgcag ggctgggggt
1441 ggggtgggtt gtgtgacttt gcagttcaac agactcaaat tcagcttatg ctggcatggc
1501 agcgcatgct gtgtgccagg cgacaagcaa ggagaggcag acccagtttg tagctgaagg
1561 gttcccgctg gctgtgggtt tagagcttca accttggggc tggtgtgtgg ctagatgttt
1621 tctgatcatt ctgacattta atccacacac ttcgtccccc acttagagaa tgtagggtga
1681 atcacagaag gaaagtgacg tgcccaaggt gacccagcta ttcaattaga ctcaatggaa
1741 tctaagctgc caggttgcag atgtctggtt ctggggttca ggggccacac tcctggcctt
1801 ggtcctggcc ctgcagacag gcccctaaac actgtgctaa tgggtggggc cgcagttcac
1861 cttcagttcc tgccaagagg ctagattcac agtcacaggg gctgcgtagt tctcagagac
1921 ccctcaagca gcagtctttg cctgaggacc tcccttggtt cctgccccct cccggcgctg
1981 actccgggcc aggagaggaa aggctgtctc cacccacctc ttgcactctc ccttctcctt
2041 tataaaggcc ggaacagctg aagggtggca acttctcctg cagccgggag cagcctgcct
2101 gcctcccccg ctgcctccct gagggcttcc ctccggccgc cagcgcccat cttattccag
2161 agagatattt tgcgcacaca cacatacaca cacgcgcaaa agggaaagga ggaaaaaaaa
2221 aaagcccacc ctctagcttc gttgcaacga gaaagccgga gcagccgcag ctcgaaaccc
2281 gcagaggaag cccagagtgg cgagcgagtg ggtagataga cagactgacc cgagccgcgt
2341 ccacctgtcg gcccggacca gcccagcgcg cagtggcgcg ccgcgctctc ggagcagccg
2401 tgcccgccgc ttgggcccct ggccagggcg cacacgctcc cgccccgcca cccggcccgg
2461 gcgggagttt gcacctctcc ctgcccgggt gttcgggccg ccgctgcaaa gccaactttg
2521 gaaaaagttt ttttttggag acttgggctt ggaggtcccc agctctgcgc tttctgattt
2581 gggggtccgt tccagaaaat gttgcaaaaa agctaagcca gcaggcagag gaacacgcct
2641 ttagcgggcg agtgaagacg aaccataggc tgccgtgttc cttttcctct ctgaggttgg
2701 agtcccctgc gcgcccccac acggctagac gccttggctg gttcgcgacg cagcccccag
2761 actgtggatg ctcgcgtggg ctcgggatcc gcccaggtag cggctttgga ccccggtccc
2821 ttgtccaggt cctccccagc cccccagcga cggagccggg gccgggggcg gcggcgcccg
2881 ggggccatgc gggtgagccg cggcggcggc tgcagcggcc tgagcgcctg atcgcggggg
2941 acccgagcgg agcccaccct cctccccagc cccccaccct ggccgcgggg gcggcgcgct
3001 ccgtctacgc gtccggggcc ccgcggggcc gggcccggag tcggcatgaa tcgctgctgg
3061 gcgctcttcc ttcctctctg ctgctacctg cgcctggtca gcgccgaggt gagttgcgac
3121 ggcggctggg gctggatcct tccctggttg tcccagcccc cacgcctggc cgccccctcc
3181 tctccctgca gtgaactttg gagccttgca gcgcgtgagt caggcgccgg gcactgggtg
3241 gcccaagggc tgggaggcca ggtccggggt gctgggctcc tggggaggag gcagcggtgg
3301 gtttctttcc agtggaccaa tctagatccc taaagctttt agcgtcctag aaggtgtgtg
3361 ctgccctgcc ccctgcctca ggagctagag atc
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS MUSCSIS02 601 bp ds-DNA ROD 08-MAY-1991
DEFINITION Mouse platelet-derived growth factor B chain (c-sis) gene, exon 2.
ACCESSION M64845 M55394
KEYWORDS c-sis proto-oncogene; platelet-derived growth factor;
platelet-derived growth factor B chain; proto-oncogene.
SEGMENT 2 of 6
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 601)
AUTHORS Bonthron,D.T., Sultan,P. and Collins,T.
TITLE Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding
the B chain of platelet-derived growth factor
JOURNAL Genomics 10, 287-292 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M64844:3109..>3393,<1..301)
/number=1
/note="approximate 7.7 kb gap"
/gene="c-sis"
exon 302..398
/number=2
/gene="c-sis"
BASE COUNT 125 a 156 c 185 g 135 t
ORIGIN
1 gatcttaccg gggagacaaa tgtggacaag ccagtggagc tgggcaccgt ggagggctag
61 ggttgagtgt cccagcatgc tctgctctga gctattcagg ccctgggtcc tcagtgctcc
121 tggttcagcc ttggatctgg cctgccccac ccttacttag ccttacttac tatttgttgg
181 ggatggcggg ggatgggggt ggcttgtagg aactttgtgc aagagaaaag cacttggttg
241 gtaagagagc cacagtgaac cttcacccca gttcacacag ttcctggtgt ctgaccgaca
301 gggggatccc attcctgagg aactgtatga aatgctgagc gaccactcca tccgctcctt
361 tgatgatctt cagcgcctgc tgcacagaga ctccgtaggt aaatcggacc ctcctccaga
421 acctcagcct ctactgatcc gtagcacatc ctagtggcca cacctactac ccagggcagg
481 gcagagtagg cagactggtt ggtacctggg atgtagggtg gggcagaaac agcacccaca
541 tgtggctcta gtttggtgcg gagggtgggg ttcctggagc acactggggc agggacagag
601 t
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS MUSCSIS03 928 bp ds-DNA ROD 08-MAY-1991
DEFINITION Mouse platelet-derived growth factor B chain (c-sis) gene, exon 3.
ACCESSION M64846 M55394
KEYWORDS c-sis proto-oncogene; platelet-derived growth factor;
platelet-derived growth factor B chain; proto-oncogene.
SEGMENT 3 of 6
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 928)
AUTHORS Bonthron,D.T., Sultan,P. and Collins,T.
TITLE Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding
the B chain of platelet-derived growth factor
JOURNAL Genomics 10, 287-292 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M64845:399..>601,<1..823)
/number=2
/note="approximate 1.0 kb gap"
/gene="c-sis"
exon 824..913
/number=3
/gene="c-sis"
BASE COUNT 224 a 238 c 272 g 194 t
ORIGIN
1 gatctaggag ccccagggcg ccataaggag gtggcagaag ttcataccca gcaattcctt
61 tgctgtcctt caccaccgag agacaaaggg gtctctccat cttcgagatc aagttcaagg
121 ccttctggtc accctaatag tagccagccc tggccagcgt ctcggggcag tgtcagtgtg
181 acaaggagat gtcaccaagg aagctggtag cactgagagg aaaggacttc agcttagaga
241 agggagctgt ggctactcac aggaagaggc acagaagccc aggatgaatg ccgaggaatg
301 ccaacctagt gtggctgatg cgggccctcc cacccccttc cctctccacc ctttctctcc
361 agaccagtag ggccattgtc aaggctccag aaggctgtgt tgggctgctg ggctgctggc
421 ccaaggggat tctgggaatt tccccattca gcacttccta tgggaacgtt ttagagggca
481 ctgagaactg gcctccagtg ctctgggtcc ctgctccacc ctggaggctg aggagggctc
541 tctgacagta gcagagggga agggttattt ttaacttcat taacatcaag ttctggccaa
601 aaatggggct aaaaacacag agggaggctg gaggctctca aagatatagt taggcctacc
661 cctgccagtc ccactaccga tagggctgct caaggctttg agagccaggt cgcctattca
721 gagccaggaa cctcaggttt agaggatgct aagggtggga ctttggtgta gagaagccgt
781 ccttgacatg agccagcacg tctaactatg ctttcccctg cagatgaaga tggggctgag
841 ctggacttga acatgacccg agcacactcc ggagtcgagt tggaaagctc atctcgaggg
901 aggaggagcc taggtaaaat gaggatcc
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS MUSCSIS04 223 bp ds-DNA ROD 08-MAY-1991
DEFINITION Mouse platelet-derived growth factor B chain (c-sis) gene, exon 4.
ACCESSION M64847 M55394
KEYWORDS c-sis proto-oncogene; platelet-derived growth factor;
platelet-derived growth factor B chain; proto-oncogene.
SEGMENT 4 of 6
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 223)
AUTHORS Bonthron,D.T., Sultan,P. and Collins,T.
TITLE Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding
the B chain of platelet-derived growth factor
JOURNAL Genomics 10, 287-292 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M64846:914..>928,<1..15)
/number=3
/note="approximate 1.4 kb gap"
/gene="c-sis"
exon 16..221
/number=4
/gene="c-sis"
BASE COUNT 39 a 74 c 69 g 41 t
ORIGIN
1 gcctcttccc tccagggtcc ctggcagcag cagagcctgc tgtaatcgcc gagtgcaaga
61 cgcgcacaga ggtgttccag atctcgcgga acctcatcga tcgcaccaac gccaacttcc
121 tggtgtggcc gccctgtgtg gaggtgcagc gctgctccgg ctgctgcaat aaccgcaatg
181 tgcaatgccg ggcctcgcag gtgcagatgc ggccggtcca ggt
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS MUSCSIS05 311 bp ds-DNA ROD 08-MAY-1991
DEFINITION Mouse platelet-derived growth factor B chain (c-sis) gene, exon 5.
ACCESSION M64848 M55394
KEYWORDS c-sis proto-oncogene; platelet-derived growth factor;
platelet-derived growth factor B chain; proto-oncogene.
SEGMENT 5 of 6
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 311)
AUTHORS Bonthron,D.T., Sultan,P. and Collins,T.
TITLE Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding
the B chain of platelet-derived growth factor
JOURNAL Genomics 10, 287-292 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M64847:222..>223,<1..140)
/number=4
/note="approximate 1.25 kb gap"
/gene="c-sis"
exon 141..285
/number=5
/gene="c-sis"
BASE COUNT 70 a 83 c 91 g 67 t
ORIGIN
1 ttcagagctg tcactctgca gacgagcctg ggttttggct ttcgaggaaa gactccagca
61 caggacactt gccaggcgcg tgaggccgct cctgcactga tggcttctac agggaagttt
121 tgctcattct tgtcctccag gtgagaaaga ttgagattgt gcgaaagaag cccatcttca
181 agaaggccac agtgaccttg gaggaccacc tcgcctgcaa gtgtgagaca atagtgaccc
241 ctcggcctgt gactagaagt cctgggacat ccagggagca gcgaggtaag ctgccttccc
301 aggggctgct c
//GenBank-Updates@genbank.bio.net (05/08/91)
LOCUS MUSCSIS06 1134 bp ds-DNA ROD 08-MAY-1991
DEFINITION Mouse platelet-derived growth factor B chain (c-sis) gene, exons 6
and 7.
ACCESSION M64849 M55394
KEYWORDS c-sis proto-oncogene; platelet-derived growth factor;
platelet-derived growth factor B chain; proto-oncogene.
SEGMENT 6 of 6
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1134)
AUTHORS Bonthron,D.T., Sultan,P. and Collins,T.
TITLE Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding
the B chain of platelet-derived growth factor
JOURNAL Genomics 10, 287-292 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
mRNA join(M64844:2070..3108,M64845:302..398,M64846:824..913,
M64847:16..221,M64848:141..285,10..158,457..>1134)
/gene="c-sis"
/partial
intron order(M64848:286..>311,<1..9)
/number=5
/gene="c-sis"
CDS join(M64844:3046..3108,M64845:302..398,M64846:824..913,
M64847:16..221,M64848:141..285,10..134)
/product="platelet-derived growth factor B chain"
/gene="c-sis"
/codon_start=3046
exon 10..158
/number=6
/gene="c-sis"
intron 159..456
/number=6
/gene="c-sis"
exon 457..>1134
/number=7
/gene="c-sis"
BASE COUNT 215 a 365 c 292 g 262 t
ORIGIN
1 ctcgagcagc caagacgcct caagctcggg tgaccattcg gacggtgaga atccgccggc
61 cccccaaagg caagcaccga aagtttaagc acacccatga caaggcggcc ctgaaggaga
121 ccctcggagc ctaggggcgt cggcaagagt gtgggcaggt gaggagccaa caagaaaaaa
181 caagcctcag ctactccctg gctttcagct actccctggc tgtgacttag ataggctccg
241 tgagaaccag cagaggcatt tgctcctgcc taactgagcc tcaacctctc tgaaacaggg
301 tgcctgtctc actcaaattt cccatagctc ctccgtctca gccttgggac ctgctggaaa
361 tcagcatggt ggcaggagcc ctagcccctt gccttggtat gggggccacg gggactcttg
421 agctacctct gaccctgtat ccttctctgc ccacagggtt atttaatatg gtatttgctg
481 tattgccccc atggggtcct tggagtgata atgttgttcc cctcgtccgt ctgtctcgat
541 gcctgattcg gacggccaat ggtgcttccc tcaccccgtg tgcccggcca cctccaccag
601 cagcgatccc tcagcccgcc ctgcagctcc acatgcaaag gactccactc caggctgcag
661 gcttctcttg actccaagaa cctggaacaa gtgtgcagga gccttgccgg gggactgtgg
721 actggcccca gagcctggca cttagcctga ggacctctgc atgtcctgcc tggttcctgg
781 accactggcc agccagcagg gaacatgttc aggcaggcta gggtcccttg cagtcctgtg
841 gcagggagca cagactggag gaactctgat ggcacccaga tctgccacgc actcatctct
901 tcctgtcccc tcagcccaca gtggcttttc attttataag acatgaactc ctctgggcag
961 gtggccacaa gccttctctg atggattaga ggtgcagtgt gcgtgtgacc tgggccatgt
1021 ccctgcctct ttccacttcc cctacgttca cttccggttc atttctctac ctccactctg
1081 tgtcttcttc ctcatgtgcc cttcagtctg ctcctccacg gggtgttcgg atcc
//