GenBank-Updates@genbank.bio.net (05/09/91)
LOCUS DROTN881 436 bp ds-DNA INV 09-MAY-1991
DEFINITION D. melanogaster copia-like 8.8 kb transposon in tropomyosin I gene
of flightless mutant Ifm(3)3, segment 1.
ACCESSION M10908
KEYWORDS transposon; tropomyosin; tropomyosin I.
SEGMENT 1 of 2
SOURCE D. melanogaster (flightless strain Ifm(3)3) DNA.
ORGANISM Drosophila melanogaster
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (bases 1 to 436)
AUTHORS Karlik,C.C. and Fyrberg,E.A.
TITLE An insertion within a variably spliced drosophila tropomyosin gene
blocks accumulation of only one encoded isoform
JOURNAL Cell 41, 57-66 (1985)
STANDARD simple staff_review
COMMENT The flightless mutant strain Ifm(3)3 was derived from Canton-S
stock after males were fed ethyl methanesulfonate. Ifm(3)3 lacks
the embryonic isoform (#129) of tropomyosin I, but contains normal
amounts of the thorax isoform (#127). The tropomyosin I gene is
located in the 88f subdivision of chromosome 3 [Cell 41, 57-66
(1985)].
The 8.8 kb transposon that has disrupted the transcritpion of this
gene is present in six highly conserved copies in Canton-S strain
[Cell 41, 57-66 (1985)].
For the normal allele see separate entry.
FEATURES Location/Qualifiers
misc_recomb 31^32
/note="TMI DNA end/tn8.8 DNA start"
BASE COUNT 107 a 97 c 116 g 116 t
ORIGIN 303 bp upstram of MstI site; chromosome 3.
1 ccacacagtt tattatatat atatatatat aaattaatta aatgtatggt gcaggtccct
61 cgccgcggtc tccggcgtag gttgcaggta acggggggtt cctctgtcac tgggaggcag
121 ggcggttgcc gcagacctct tctcctagat tgggagatat ggtgggagaa cgtctctccg
181 ttgttgactg cccttaaggc tagccaacca attcaatgat aacaggcagt tagctggagt
241 tagattgaag gcgcgatgcg ctcttttatt ggaatacaaa tcaaactgac tataagctac
301 aagggaaaac atcatagcgg cctctgccaa tgcgcagagc ttctgccggc tatgcatgag
361 cttccggcca aatgcttggt cagcaatttg accggtgctg gtgtgcggac gatcagtccg
421 gttaacttag ttaact
//