GenBank-Updates@genbank.bio.net (05/09/91)
LOCUS RABHBBA1A2 1399 bp ds-DNA MAM 09-MAY-1991
DEFINITION Rabbit beta1-globin with 2 ivs, type 2 allele.
ACCESSION J00660
KEYWORDS beta-1-globin; beta-globin; globin.
SOURCE Rabbit (New Zealand white).
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 76 to 135)
AUTHORS Baralle,F.E.
TITLE Complete nucleotide sequence of the 5' noncoding region of human
alpha- and beta-globin mRNA
JOURNAL Cell 10, 549-558 (1977)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1399)
AUTHORS Hardison,R.C., Butler,E.T., Lacy,E., Maniatis,T., Rosenthal,N. and
Efstratiadis,A.
JOURNAL Cell 18, 1285-1297 (1979)
STANDARD full staff_review
COMMENT On chromosome: 5'-beta4-(8kb)-beta3-(5kb)-beta2-(7kb)-beta1.
Compared with NBRF data.
FEATURES Location/Qualifiers
CDS join(129..220,347..569,1143..1271)
/note="beta1-globin"
/codon_start=129
prim_transcript 76..1364
/note="beta1-globin mRNA and intron"
exon 129..220
/note="beta1-globin exon 1"
intron 221..346
/note="beta1-globin intron A"
exon 347..569
/note="beta1-globin exon 2"
allele 411..411
/note="a in type 1; c in type 2"
allele 424..424
/note="a in type 1; g in type 2"
allele 484..484
/note="g in type 1; a in type 2"
intron 570..1142
/note="beta1-globin intron B"
allele 1012..1012
/note="t in type 1; c in type 2"
allele 1132..1132
/note="t in type 1; c in type 2"
exon 1143..1271
/note="beta1-globin exon 3"
allele 1164..1164
/note="a in type 1; g in type 2"
BASE COUNT 329 a 294 c 316 g 460 t
ORIGIN HaeIII site.
1 ccaatctaca cacggggtag ggattacata gttcaggact tgggcataaa aggcagagca
61 gggcagctgc tgcttacact tgcttttgac acaactgtgt ttacttgcaa tcccccaaaa
121 cagacagaat ggtgcatctg tccagtgagg agaagtctgc ggtcactgcc ctgtggggca
181 aggtgaatgt ggaagaagtt ggtggtgagg ccctgggcag gttggtatcc tttttacagc
241 acaacttaat gagacagata gaaactggtc ttgtagaaac agagtagtcg cctgcttttc
301 tgccaggtgc tgacttctct cccctgggct gttttcattt tctcaggctg ctggttgtct
361 acccatggac ccagaggttc ttcgagtcct ttggggacct gtcctctgca catgctgtta
421 tgagcaatcc taaggtgaag gctcatggca agaaggtgct ggctgccttc agtgagggtc
481 tgaatcacct ggacaacctc aaaggcacct ttgctaagct gagtgaactg cactgtgaca
541 agctgcacgt ggatcctgag aacttcaggg tgagtttggg gacccttgat tgttctttct
601 ttttcgctat tgtaaaattc atgttatatg gagggggcaa agttttcagg gtgttgttta
661 gaatgggaag atgtcccttg tatcaccatg gaccctcatg ataattttgt ttctttcact
721 ttctactctg ttgacaacca ttgtctcctc ttattttctt ttcattttct gtaacttttt
781 cgttaaactt tagcttgcat ttgtaacgaa tttttaaatt cacttttgtt tatttgtcag
841 attgtaagta ctttctctaa tcactttttt ttcaaggcaa tcagggtata ttatattgta
901 cttcagcaca gttttagaga acaattgtta taattaaatg ataaggtaga atatttctgc
961 atataaattc tggctggcgt ggaaatattc ttattggtag aaacaactac accctggtca
1021 tcatcctgcc tttctcttta tggttacaat gatatacact gtttgagatg aggataaaat
1081 actctgagtc caaaccgggc ccctctgcta accatgttca tgccttcttc tctttcctac
1141 agctcctggg caacgtgctg gttgttgtgc tgtctcatca ttttggcaaa gaattcactc
1201 ctcaggtgca ggctgcctat cagaaggtgg tggctggtgt ggccaatgcc ctggctcaca
1261 aataccactg agatcttttt ccctctgcca aaaattatgg ggacatcatg aagccccttg
1321 agcatctgac ttctggctaa taaaggaaat ttattttcat tgcaatagtg tgttggaatt
1381 ttttgtgtct ctcactcgg
//