GenBank-Updates@genbank.bio.net (05/10/91)
LOCUS MUSCYTCB1 4828 bp ds-DNA ROD 10-MAY-1991
DEFINITION Mouse testosterone 16-alpha-hydroxylase (CB) gene, complete cds.
ACCESSION M24263 J04471 M24265 M24268
KEYWORDS cytochrome P-450; testosterone 16-alpha-hydroxylase.
SOURCE Mouse (strain BALB/cJ) spleen DNA, clone lambda-27.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 4828)
AUTHORS Wong,G., Itakura,T., Kawajiri,K., Skow,L. and Negishi,M.
JOURNAL Unpublished (1989)
STANDARD full staff_review
REFERENCE 2 (sites)
AUTHORS Wong,G., Itakura,T., Kawajiri,K., Skow,L. and Negishi,M.
TITLE Gene family of male-specific testosterone 16-alpha-hydroxylase
(C-P-450-16-alpha) in mice: Organization, differential regulation,
and chromosome location
JOURNAL J. Biol. Chem. 264, 2920-2927 (1989)
STANDARD full staff_review
COMMENT
[J. Biol. Chem. 264, 2920-2927 (1989)] sites.
[Unpublished (1989)] revises [J. Biol. Chem. 264, 2920-2927
(1989)].
Draft entry and computer-readable sequence for [J. Biol. Chem. 264,
2920-2927 (1989)] kindly submitted
by G.Wong, 13-JUL-1989.
The sequence submitted by the authors revises the sequence which
was published in reference [J. Biol. Chem. 264, 2920-2927 (1989)].
[J. Biol. Chem. 264, 2920-2927 (1989)] Author address: G.Wong
National Institute of Environmental Health Sciences
P.O. Box 12233
Research Triangle Park, North Carolina 27709
e-mail: WONG_G@NIEHS
FEATURES Location/Qualifiers
CDS join(555..743,1659..1830,2099..2251,2342..2502,3127..3303,
3487..3628,3825..4012,4221..4362,4463..4653)
/note="testosterone 16-alpha-hydroxylase (CB)"
misc_signal 454..458
/note="TATA box"
prim_transcript 486..4739
/note="CB mRNA and introns"
exon 555..743
/note="testosterone 16-alpha-hydroxylase (CB), exon 1"
intron 744..1658
/note="CB intron A"
exon 1659..1830
/note="testosterone 16-alpha-hydroxylase (CB), exon 2"
intron 1831..2098
/note="CB intron B"
exon 2099..2251
/note="testosterone 16-alpha-hydroxylase (CB), exon 3"
intron 2252..2341
/note="CB intron C"
exon 2342..2502
/note="testosterone 16-alpha-hydroxylase (CB), exon 4"
intron 2503..3126
/note="CB intron D"
exon 3127..3303
/note="testosterone 16-alpha-hydroxylase (CB), exon 5"
intron 3304..3486
/note="CB intron E"
exon 3487..3628
/note="testosterone 16-alpha-hydroxylase (CB), exon 6"
intron 3629..3824
/note="CB intron F"
exon 3825..4012
/note="testosterone 16-alpha-hydroxylase (CB), exon 7"
intron 4013..4220
/note="CB intron G"
exon 4221..4362
/note="testosterone 16-alpha-hydroxylase (CB), exon 8"
intron 4363..4462
/note="CB intron H"
exon 4463..4653
/note="testosterone 16-alpha-hydroxylase (CB), exon 9"
BASE COUNT 1127 a 1138 c 1211 g 1102 t 250 others
ORIGIN Chromosome 15.
1 ccactactgg ccctcactcg cccacaggga tttcagctgc cattcccgac tgccctgctt
61 ttgcccattg gggctccagc ctcatctgga aacagcctcc cactgctcac acacacagaa
121 gtgattgaca tgatgccagt caaccctcat gtctgccagg aaagtgctcc atgaagatct
181 aggaggtctc attcctctct gaggcaatgt cctcaagccc tctaagattt gcatgagtag
241 caaacccgat gaatttcctg cacacaatga tcagaacatt cgtcctgaag caggagtcca
301 cgagatatct gcctaccatg ttcagcccag cagaatcaga atgctaaact cctgaaagga
361 actgaacatc actagctcct ccctacaggt ggacaaacaa aacacagtgt tggggcagga
421 cacagaggac aaagggcaac cctggcactc ctttataagg cagcaggatc caagcttggg
481 ccagtctgat tctaggtgtt acattgagtg ttgttcattg gtctctggaa agcctgggca
541 gaagtggggt agccatggag ctgctgactg gggctggcct gtggtctgtg gccatattca
601 ccgttatctt catattactg gtggacctga tgcaccggca ccagcgctgg acttctcgct
661 acccaccggg ccctgtgcca tggcctgtgc tgggtaacct gctgcaggtg gacctggata
721 acatgccata cagcttgtac aaggtgagtg actcagcaat ggatggtatg tgaggttata
781 gtgtccatag tggcacatag tagggtttga gccacagttt agtggctaga tctagatccc
841 caagagggaa taggcttaga catgtttttg tggcagccac tgggaatttc tagggcaaag
901 gattggggga ataaaatcca agggtgaagc aaggtatgaa aggaatgttc agcctagttg
961 gacaggacag gacctgtaga ggtcccaagt actttatgtt cctgtcaatg atgaggtctt
1021 gatatgctgt gaagtctacc actcnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnggtttc tgggtctggc
1261 cagggaactg ctggggtgtg acatgtacta tgacaccttt tgctaaactt aaaagataag
1321 caccacatta ggtaggcctc ctcacgcatg ggatggagct caagcaagag cattttccca
1381 ggatatatga gcaaggttca ataacaagca agatacacac aaaatagata tgtacacatg
1441 caaatacaga gacagagaga tacatggagt cacatacaca tatgcacaca tacttaaatt
1501 cacatacaca aacatgcata tgtaaacata cacaaatgtg cactcacaca caaagaaact
1561 gcctggcacc ctctcacttt gacattgttg tgcagtgaaa ctggttctat tatctgtggg
1621 cacctctact tcctatgtgc tttgtccctc tacgtcagct tcaaaaccgc tatggtgacg
1681 tgttcagcct gcagatgggc tggaagccta tggttgtgat caatggactg aaggcaatga
1741 aggaagtgct gttgacctgt ggagaggaca ctgctgaccg ccctcaagtg cccatctttg
1801 agtacctggg tgtgaagcct ggatcccaag gtaaagggct gtgtggacgg tggatttggg
1861 ttcagacgtg tgggaataag ctgaggaagc acaggttatg aatgtgggtg ggaatgtggt
1921 caagcaattc acagaagagt cactggaatc caggaggact acccagaagg catgcactgg
1981 attgtgatag caaggttttg agaggctcat ggccaggaca gaacacagaa aagagaattg
2041 aggagagaag gagacagtag agttgggcat tcttggttac ataccgatgt gtctgcaggt
2101 gtggtccttg caccctacgg gcccgagtgg cgagagcaga ggcgattctc tgtgtctacc
2161 ctgcgcaact ttggcctggg caagaaatca ctggaggact gggtgaccaa ggaggccaga
2221 cacctctgtg atgccttcac cgcccaggct ggtgggtgat gggtgaggga tgtagctggg
2281 cacagggaga catgggcagt ccattgactt gcttgcatct ccattccata tccactccca
2341 gggcagccca tcaatcccaa caccatgctg aacaacgctg tgtgcaatgt gattgcatct
2401 ctcatttttg cccgtcgctt tgaatatgaa gacccttacc tcatcaggat gcagaaagta
2461 ctggaagata gtttgacaga aatctctctg gcttattctg aggtaggagg ttcagggcag
2521 gctacagagc acttctgtgc agtccatctt cgctgaggga gctatgtgcc aaggctgtga
2581 gagaggcctt cttaggttca actccagaag gatatgactg ttgacaactg ttagatgaca
2641 ggatgggaga agtggaccaa ggttagtatt tccagaaagg gagagaacct gggccttctt
2701 ttgcatgtaa gacacaaagc ctgtggttgt cgttggggta gaatattcct gttctcctag
2761 ggctgagaga acctttactt aggtggctct tgcaaattta ataattgaag ataggacagg
2821 ggagaggtag ggacaaacag gctctgggtc cattgtgaag gaggctggaa actgagcctg
2881 gtccaggtgg ataaggagca tcaatagaac cgaggaacca gtcaaatggt gagtgggtaa
2941 ggactgccaa gcaagccagc caacccactt tgatgtcttg agactcatgt ggatagagac
3001 attgactcac acactgtcta tcacttgctt cacacactag gctcatagca ccatactgtt
3061 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntactgtatc
3121 tcacaggttc ttaatatgtt ccccatactc ctgcgcatcc caggactgcc tgggaaggtc
3181 ttccaaggtc agaagtcctt actggccata gtggagaatc tgttgactga gaataggaac
3241 acctgggacc ctgaccagcc accccgaaat ttgactgatg ccttcctggc agagatagag
3301 aaggtgactg gcagattcaa acgatgttgc caggggctgt gggctgatgt cctgtgatct
3361 gggagggtag atgggtagag tcctgtgtat catcaagtga ctcagcacct gggctgcctc
3421 agggacaatg ggaggccatg tgggacttcc tgtccctgct aagcacatca tctctgcctg
3481 gcccaggtaa aggggaatgc tgagagcagc ttcaatgatg agaacctgcg catggttgtg
3541 ctagacctgt tcactgcagg gatggtgacc acctcaacca cactgtcctg ggccctgctg
3601 ctcatgatcc tgcatccgga tgtgcagcgt gagcctggtg gggctaggag ggaggtagag
3661 gcacaatccc cagtgacttg agattcttgt ggcacccagt gctaactcaa cccagactcc
3721 agtgccgctc cctcttgttt ctcacatcgc ctcagtcctt accatggttg taagacaggg
3781 atgtcccctg tgactttttc actgaggtaa tgctgtccct ccaggcagag tccaacagga
3841 aatcgatgcg gtcatagggc aggtgcggca tccagagatg gcagaccagg ctcgtatgcc
3901 ctacaccaat gctgtcattc atgaggtaca gcgctttggg gacattgctc cactgaattt
3961 gccacgcatc acaagtcgtg acattgaagt gcaggacttc ctcatcccca aggtaggcct
4021 gggcctgtta ctacttatca tgatcactat ccccaccctg gaaatctatt acaggccctt
4081 caagatgcta agaggctcag gggttgaggt gaatgagagg aatccaatgt gtgcagagaa
4141 agttttgcct gttatccctg gtgtccagtg tctaggcagt cccaccccag tccatgttca
4201 aattatgtgc cttctgccag gggtcaatcc tcatccccaa catgtcctcc gtgctgaagg
4261 atgagactgt ctgggaaaag cccctccgct tccatcctga acacttcctc gatgcccagg
4321 gccactttgt gaagcctgag gccttcatgc cattctcagc aggtgcctgg gggatgccta
4381 gctgcctgtc tctcccaagg gtgccttaga gggtggagaa ccaatcaggt cccagactaa
4441 ctgagccctc ttccacacac aggccgcaga tcatgcctgg gtgagcccct ggcccgcatg
4501 gagctcttcc tcttcttcac gtgcctcctg cagcacttta gcttctcagt gcccaatgga
4561 cagcccaggc ctagaaacct tggtgtcttt ccttttccgg ttgcccccta cccctaccag
4621 ctctgtgctg tgatgcgtga gcaaggacac taattccagt catggtaggc agggcaggct
4681 gagccatgca aaataaacca atcttgtggc tgctgctgtt ttctgcttca atcccagccc
4741 tctcttgctg ggtcttcaga caatagtcgc caaccaatct ttccacctgc ctcatctctt
4801 ctcaagagac aacttgactg ctgtgatc
//