GenBank-Updates@genbank.bio.net (05/10/91)
LOCUS HUMPROP2AB 3441 bp ss-mRNA PRI 10-MAY-1991
DEFINITION Human protein phosphatase 2A beta subunit mRNA, complete cds.
ACCESSION M64930 J05328
KEYWORDS protein phosphatase 2A beta subunit; regulatory subunit.
SOURCE Human fetal brain, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3441)
AUTHORS Mayer,R.E., Hendrix,P., Cron,P., Matthies,R., Stone,S.R., Goris,J.,
Merlevede,W., Hofsteenge,J. and Hemmings,B.A.
TITLE Structure of the 55 kDa regulatory subunit of protein phosphatase
2A: Evidence for a neuronal specific isoform
JOURNAL Biochemistry 30, 3589-3597 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
5'UTR 1..525
CDS 411..452
/note="upstream ORF 1"
/codon_start=411
CDS 474..542
/note="upstream ORF 2"
/codon_start=474
CDS 526..1857
/EC_number="3.1.3.16"
/note="55 kDa regulatory subunit"
/product="protein phosphatase 2A beta subunit"
/codon_start=526
3'UTR 1858..3441
BASE COUNT 943 a 800 c 803 g 895 t
ORIGIN
1 ggccaggcaa gcctgaatcc tgtccctgcc atctcgccac tgcagctcgg gtccagaaag
61 gcaccatttt gtcgcggctg cccgctctcc cagggggagg agggatcttt tttgcatttt
121 ggagcggctg ccaaggaggg gaacctgttg ggcatctccc cagacccgct tgtgagcgcc
181 tccggggcgg gcgggcggga ccagacccct cggggcacgg cgtatcttgg cacccggagg
241 cagcggaggc aggcgcagca tcctcgctgg gaactggagc tggagtgagc gcaccgcgcg
301 ggaggagccg ccgcagcctc gcagaacccg agtggaggag gtgacagctc cattgccggg
361 tttttatttt ttttctctcc gcctccccgt ctcctcctca ggctcggacc atggtgcagt
421 cccactggct cccctgcccc cctctcctgt gagactggct gcggggaggg atcatggata
481 cttgtctgcc ggcttctggt tcccacgcaa gtaagcctgc tgtcaatgga ggaggacatt
541 gatacccgca aaatcaacaa cagtttcctg cgcgaccaca gctatgcgac cgaagctgac
601 attatctcta cggtagaatt caaccacacg ggagaattac tagcgacagg ggacaagggg
661 ggtcgggttg taatatttca acgagagcag gagagtaaaa atcaggttca tcgtaggggt
721 gaatacaatg tttacagcac attccagagc catgaacccg agttcgatta cctgaagagt
781 ttagaaatag aagaaaaaat caataaaata agatggctcc cccagcagaa tgcagcttac
841 tttcttctgt ctactaatga taaaactgtg aagctgtgga aagtcagcga gcgtgataag
901 aggccagaag gctacaatct gaaagatgag gagggccggc tccgggatcc tgccaccatc
961 acaaccctgc gggtgcctgt cctgagaccc atggacctga tggtggaggc caccccacga
1021 agagtatttg ccaacgcaca cacatatcac atcaactcca tatctgtcaa cagcgactat
1081 gaaacctaca tgtccgctga tgacctgagg attaacctat ggaactttga aataaccaat
1141 caaagtttta atattgtgga cattaagcca gccaacatgg aggagctcac ggaggtgatc
1201 acagcagccg agttccaccc ccatcattgc aacaccttcg tgtacagcag cagcaaaggg
1261 acaatccggc tgtgtgacat gcgggcatct gccctgtgtg acaggcacac caaatttttt
1321 gaagagccgg aagatccaag caacagatca tttttctctg aaattatctc ttcgatttcg
1381 gatgtgaagt tcagccacag tgggaggtat atcatgacca gggactactt gaccgtcaaa
1441 gtctgggatc tcaacatgga aaaccgcccc atcgagactt accaggttca tgactacctc
1501 cgcagcaagc tgtgttccct ctatgaaaat gactgcattt ttgataaatt tgagtgtgtg
1561 tggaatgggt cagacagtgt catcatgaca ggctcctaca acaacttctt caggatgttc
1621 gacagaaaca ccaagcgtga tgtgaccctt gaggcttcga gggaaaacag caagccccgg
1681 gctatcctca aaccccgaaa agtgtgtgtg gggggcaagc ggagaaaaga cgagatcagt
1741 gtcgacagtc tggactttag caaaaagatc ttgcatacag cttggcatcc ttcagaaaat
1801 attatagcag tggcggctac aaataaccta tatatattcc aggacaaggt taactaggtg
1861 gacaagttat tacttaataa tctcacatac tgaatactag tcaaacaagt ttttaaatgt
1921 ttctttgggt cttcatttga tgcattgact ttaatttccc tatacaggaa atgattggaa
1981 tagaattaaa aggagtccaa cattcccagc tccccagttc taagaaactt ttgtcaaacc
2041 caataggttt gggacacttc tgtttagaat tgaaagctgc cagctaacag taattcttcc
2101 atagttgact tgaacttctg atgcttttat tgcccagttt tctctggtgg gtccagtgtt
2161 ttgttcctag gtgtctgctg cgataaaatg aggttgtctg tagtatttaa ggagaaaaga
2221 gataagtttt ttttaattaa gcaattccat ttgattgaaa aaaatcaaca aaaaataaac
2281 accgtttact cttagacaaa ttcttcttgt tttgtgaaaa accagaacta gtcagtatct
2341 cctgcccctc caccattttt ttttccattt tccattttcc tttgaacaat ttcatttaag
2401 ccagagattt attgcatgaa gctgagaaga ggatgcagaa tgacaaggaa agggcacatc
2461 aaccctgcta tgctcttttt ttgtaagctc catagaaaca gcctgagaat ttggctaggg
2521 aacttgaatg cttcagggga cagaaagaga gcactttcga cacagtgctt cccagagtga
2581 gcttggcagg gccaggcggg gccaaattcc atctgctgcc ttgttactct tgctttttgt
2641 gctcttaaat ggctccatat aatcttctac ttacatgttc cttggctttt ttctcttcaa
2701 ccttttccag cttatttatt ccattgactt ctaaaggccg agtcctgggt gcttattatc
2761 tggtgttcta aatgaagcag taagttggaa gcagtgccac cacccctgag tccctgagaa
2821 aggctggtct gttctttttg ggtgtttctc ctaagcagca ccctcccctc ctcctggttt
2881 tggtaaccaa aagtaacaat ccatcaacct ccattgtacc tagaacaaaa atagccaata
2941 aaaacgctga gttgtgaagt ccaatcaggc acttctaact caccccaagc tcgccatctg
3001 gaaaaacaga ccagaaggct tctcttctac agaaatgaac tgtggggaaa tcaagcagct
3061 gtgacatgaa gtgaatgaag tccacttgaa gctgtggaag atggttcatc cttttcccca
3121 gttgaggatc cagatttata acttctagaa agccatttcc agaaggttct atgtggcaca
3181 cccctaggaa aggcactaaa tgcatgcaaa ggatttataa acttaggaaa gtagatgggt
3241 ggagtccaga aaactggttc tgggttaata tctctacatc tgtcttgatg actcatttct
3301 cctaactccc atttagtgca gggtaaatgg tttgagatga gagtttttca atgaaaggga
3361 aattttcttt cagtttacag atgtattaga agtcctgact ttcaagtgta atttgctttg
3421 gaggaggaaa aaaaaaaaaa a
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