GenBank-Updates@genbank.bio.net (05/11/91)
LOCUS ECOCYSJIHA 5720 bp ds-DNA BCT 11-MAY-1991
DEFINITION E.coli NADPH-sulfite reductase flavoprotein component (cysJ),
NADPH-sulfite reductase hemoprotein component (cysI), and 3'
phosphoadenosine 5'-phosphosulfate sulfotransferase (cysH) genes,
complete cds.
ACCESSION M23008 J05025 J05057 M27144
KEYWORDS flavoprotein; hemoprotein; sulfite reductase; sulfotransferase.
SOURCE E.coli (strain B, ATCC 11303) DNA, clone pJYW2.
ORGANISM Escherichia coli
Prokaryota; Bacteria; Gracilicutes; Scotobacteria;
Facultatively anaerobic rods; Enterobacteriaceae.
REFERENCE 1 (bases 1 to 324)
AUTHORS Ostrowski,J. and Kredich,N.M.
TITLE Molecular characterization of the cysJIH promoters of Salmonella
typhimurium and Escherichia coli: Regulation by cysB protein and
N-acetyl-L-serine
JOURNAL J. Bacteriol. 171, 130-140 (1989)
STANDARD simple staff_review
REFERENCE 2 (bases 2064 to 5720)
AUTHORS Ostrowski,J., Wu,J.-Y., Rueger,D.C., Miller,B.E., Siegel,L.M. and
Kredich,N.M.
TITLE Characterization of the cysJIH regions of Salmonella typhimurium
and Escherichia coli B: DNA sequences of cysI and cysH and a model
for the siroheme-Fe4S4 active center of sulfite reductase
hemoprotein based on amino acid homology with spinach nitrit
JOURNAL J. Biol. Chem. 264, 15726-15737 (1989)
STANDARD full staff_review
REFERENCE 3 (bases 265 to 2089)
AUTHORS Ostrowski,J., Barber,M.J., Rueger,D.C., Miller,B.E., Siegel,L.M.
and Kredich,N.M.
TITLE Characterization of the flavoprotein moieties of NADPH-sulfite
reductase from Salmonella typhimurium and Escherichia coli:
Physicochemical and catalytic properties, amino acid sequence
deduced from DNA sequence of cysJ and comparison with NADPH-cytoc
JOURNAL J. Biol. Chem. 264, 15796-15808 (1989)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for [J. Biol. Chem. 264,
15796-15808 (1989)] kindly submitted
by N.M.Kredich, 16-AUG-1989.
Draft entry and computer-readable copy of sequence [J. Biol. Chem.
264, 15726-15737 (1989)] kindly
submitted by N.M.Kredich, 16-AUG-1989.
FEATURES Location/Qualifiers
mRNA 219..>5720
CDS 285..2084
/EC_number="1.8.1.2"
/product="NADPH-sulfite reducatase flavoprotein component"
/gene="cysJ"
/codon_start=285
CDS 2084..3802
/EC_number="1.8.1.2"
/product="NADPH-sulfite reductase hemoprotein component"
/gene="cysI"
/codon_start=2084
repeat_region 3827..3856
/note="repetitive extragenic palindromic sequence"
CDS 3876..4610
/product="3' phosphoadenosine 5'-phosphosulfate
sulfotransferase"
/gene="cysH"
/codon_start=3876
BASE COUNT 1397 a 1463 c 1568 g 1292 t
ORIGIN
1 agtaccggaa aggctgtttt ttcgcattat ctaaaacgac tttagttgcg caaaatcgct
61 gatttatctt aatgattggc taaattcatt tgtttttcat taggttggtt aatctatttt
121 gttgttaaag actattgcta aaacaggtta gtcgatttgg ttattagtta tcgctatccc
181 gtctttaatc cacaccgttt gccccgttaa ccttaccttc tcttctgttt tatgggcgct
241 gacagggcgc agaaacagct ttgcttactg gaacataacg acgcatgacg acaccggctc
301 cactgactgg gttgcttccg cttaacccgg agcaactggc acgccttcag gcggccacga
361 ccgatttaac tcccacccag cttgcctggg tttctggcta tttctggggc gtactcaatc
421 agcagcctgc tgcgcttgca gcaacgccag cgccagctgc agaaatgccg ggtataacta
481 ttatctccgc ctcgcaaacc ggcaatgcgc gccgggttgc tgaagcatta cgtgatgatt
541 tattagcagc aaaactgaac gttaagctgg tgaacgcggg cgactataaa ttcaaacaaa
601 tcgccagcga aaaactgctc atcgtagtga cgtcaacgca aggggaaggg gaaccgccgg
661 aagaagccgt cgcgctgcat aagttcctgt tctccaaaaa agcgccaaag ctggaaaaca
721 ccgcgtttgc cgtgtttagc ctcggcgata cgtcttatga atttttctgc cagtccggga
781 aagatttcga cagcaagctg gcggaactgg gtggtgaacg cctgctcgac cgtgtcgatg
841 ccgatgttga ataccaggct gctgccagcg agtggcgcgc ccgcgtggtt gatgcgctta
901 aatcgcgtgc gcctgtcgcg gcaccttcgc aatccgtcgc tactggcgcg gtaaatgaaa
961 tccacaccag cccgtacagc aaagacgcgc cgctggtggc tagcctctct gttaaccaga
1021 aaattaccgg gcgtaactct gaaaaagacg ttcgccatat cgaaattgac ttaggtgact
1081 cgggcctgcg ttaccagccg ggtgacgcgc tgggcgtctg gtatcagaac gatccggcac
1141 tggtgaaaga acttgtcgaa ctgctgtggc tgaaaggcga tgaacctgtc accgtcgagg
1201 gcaaaacgtt gcctctgaac gaagcgctac agtggcactt cgaactgacc gtcaacaccg
1261 ccaacattgt tgagaattac gccacgctta cccgcagtga aacactgctg ccgctggtgg
1321 gcgataaagc gaagttacag cattacgccg cgacgacgcc gattgttgac atggtgcgtt
1381 tctccccggc acagcttgat gccgaagcgc taattaatct gctgcgcccg ctgacgccgc
1441 gtctctattc cattgcctcc tcgcaggcgg aagtcgagaa cgaagtacac gtcaccgttg
1501 gtgtggtgcg ttacgacgtg gaaggccgcg cccgtgccgg tggtgcctcc agcttcctcg
1561 ctgaccgcgt ggaagaagag ggcgaagtcc gcgtatttat cgaacataac gataacttcc
1621 gcctgccagc caatccagaa accccggtga ttatgattgg cccaggcacc ggcatcgcgc
1681 cgttccgcgc ctttatgcag caacgtgctg ccgatgaagc gccgggaaaa aactggctgt
1741 tctttggcaa cccgcacttt acggaagatt tcctctacca ggtggagtgg cagcgctacg
1801 tcaaagaggg tgtgctgacg cggatcgatc tcgcctggtc gcgcgaccaa aaagaaaaag
1861 tttacgtaca agacaaactg cgcgaacagg gcgcggagct gtggcgctgg atcaatgacg
1921 gtgcccacat ttatgtctgc ggtgacgcta atcgcatggc gaaagacgtt gagcaggcac
1981 ttctggaagt gattgccgaa tttggtggca tggacaccga agcggcggat gaatttttaa
2041 gtgagctgcg cgtagagcgc cgttatcagc gagatgtcta ctaatgagca tgagcgaaaa
2101 acatccaggg cctttagtgg tcgaaggaaa actgacagac gccgagcgca tgaagcttga
2161 aagcaactac ctgcgcggca ccattgcgga agatttaaac gacggtctga ccggcggctt
2221 taagggcgac aacttcctgc tgatccgctt ccacggcatg tatcagcagg atgaccgcga
2281 catccgcgcc gaacgtgctg aacagaagct ggagccgcgc cacgcgatgc tgttgcgctg
2341 ccgtctgccg ggtggggtga ttaccactaa acagtggcag gcgatagaca aatttgccgg
2401 tgaaaacacc atctatggca gcattcgcct gaccaaccgc cagacgtttc agttccacgg
2461 cattctgaaa aagaacgtca aaccggtgca ccagatgctg cactcggttg gtcttgatgc
2521 gctggcgacc gctaacgaca tgaaccgtaa cgtactctgc acctcgaacc cttacgagtc
2581 gcagctacac gcggaagcgt acgagtgggc gaagaagatt tctgagcatc tgctgccgcg
2641 tacccgcgcg tatgcggaga tctggctcga ccaggaaaaa gtcgccacta ctgatgaaga
2701 accgatcctc ggccagacct acctgccgcg taaattcaaa accacggtag tgatcccgcc
2761 acagaacgat atcgatctgc acgccaacga catgaacttc gtggcgatcg ccgaaaacgg
2821 caagctggtg ggctttaacc tgttggtggg cggtgggctt tccatcgaac acggcaacaa
2881 gaaaacctac gcccgcaccg cgagtgagtt tggctatctg ccgctggagc atacgctggc
2941 ggtggccgaa gccgtcgtga caactcaacg tgactggggt aaccgaaccg atcgtaaaaa
3001 tgccaaaacc aaatacacgc tggagcgcgt gggggttgag acgtttaaag cggaagtgga
3061 gcgtcgcgcg gggatcaaat ttgaaccgat ccgtccatat gagttcaccg gacgaggcga
3121 tcgtattggc tgggttaagg gcattgatga taactggcac ctgacgctgt ttatcgaaaa
3181 tggtcgcatc cttgattatc cggcgcgtcc gctgaaaacc ggcctgctgg agatcgcgaa
3241 gatccacaaa ggcgatttcc gcattacggc gaaccagaat ctgatcatcg ccggtgtacc
3301 ggaaagcgag aaagcgaaga tcgagaagat cgccaaagag agcgggttaa tgaatgccgt
3361 cacgccgcag cgtgaaaact caatggcctg cgtgtcattc ccgacttgcc cgctggcgat
3421 ggcggaagcg gagcgtttcc tgccgtcttt tatcgacaac atcgataatt taatggcgaa
3481 acatggtgtc agcgatgagc atatcgtgat gcgtgtaaca ggctgcccga acggttgtgg
3541 tcgcgcgatg ctggcggaag tgggcctggt gggtaaagcg ccgggtcgct acaacctgca
3601 tcttggcggc aaccgcattg ggacacgtat ccctcggatg tataaagaaa acatcaccga
3661 gccggaaatc ctggcgtcgc ttgatgaact gatagggcgc tgggcgaaag agcgcgaagc
3721 gggtgaaggc ttcggcgact ttacggtgcg tgcgggcatc attcgcccgg tgctcgatcc
3781 ggcgcgcgat ttgtgggatt aaccatcagc ccggtcttgt aggcctgata agacgcgtga
3841 gcgtcgcatc aggcaaggca aacagtgagg aatctatgtc caaactcgat ctaaacgccc
3901 tgaacgaact gccgaaggta gatcgcattc tggcgctggc ggaaactaac gcccaactgg
3961 aaaaactgga cgctgaaggc cgcgtagcct gggcgctgga taatctgccc ggtgaatatg
4021 tgctttcttc cagcttcggc attcaggcgg cggtgagcct gcatctggtg aatcagattc
4081 ggccggatat tccagtgatc ctcaccgata ccggttatct gtttccggaa acctaccgct
4141 ttattgacga gttaacggac aaactcaagc tcaacctgaa agtgtaccgt gctaccgaaa
4201 gcgccgcctg gcaggaagca cgctacggca aactgtggga acagggcgtt gaaggcattg
4261 aaaagtacaa tgacatcaac aaagtcgaac cgatgaaccg ggcgctgaaa gaacttaacg
4321 cgcaaacctg gtttgctggc ctgcgccgcg aacaatccgg cagccgcgcc aatttaccgg
4381 tgctggcaat tcagcgtggc gtatttaaag tgctgccgat tatcgactgg gataaccgaa
4441 ctatttatca gtacctgcaa aaacatggcc tgaaatatca cccattatgg gatgaaggat
4501 atttatcggt cggtgatacc catacaaccc gtaaatggga acctggcatg tcggaagaag
4561 aaacacgttt ctttggctta aaaagggaat gtggattgca cgaagggtaa atattgccgg
4621 ataaattaaa cgcctctgtc agaaatgatg ggggcgtttt tattttgcga gcagtattcc
4681 tgattttaaa cgtgaacgcc gctggaagaa ttatcaggta tagaatggcg tcgggtgctt
4741 gaggctgtct ggcgttaagc attcgcgagg ttccagatcc acaaaagccc caggcgatat
4801 ttctatcaac ctaggcttac gttcgaaccc aaacaattcg aatgttagtc tcttctttgc
4861 agggaggcaa gacatgctga caaaatatgc ccttgtggca atatagtgct gtgttttaca
4921 gtactgggat tcacgctgca tggtaggcca ctcgttgtgt gagttgagta tcagagaacg
4981 tggtatggag tttaaggcag ttctcgctta cgaatcgaag aagtagccca ccacgcgggg
5041 taaaacccat aagcgctaac ttaagggttg aaccatctga agaatgcgat gcctcggtgc
5101 ctcgttaaga cgatgcctcg cgttcttaat tgcgttttgt aggctgtcag ggatactgtc
5161 ccacgaatgg ccacctgtaa gctccaagat gaccattttt gttattctcc acaacgagtt
5221 agttcttctt ttcggatccg gcattctggg ggggaaatcc agcgaatggc tggattatgt
5281 cgtcaatttt ttgcggtgag tagtaatgca aatatccagc tttcgcgagt tcaggttctt
5341 tgctcgcaaa gcatccaggt gctgcaaact tttgagccgc ttaaaaagcc agttcaattt
5401 gccatcgcag acggtaacaa tcagccactt gctctgctga atattcatct tccggtaatg
5461 atgttagcaa tagcacatgg cccgctgctt ccagcgtttc cgcctgaact actcgtcctt
5521 ttcgacgatt ctcgctgagc agtcgggttt tactgattaa tgctttttcg ggaggaagtg
5581 atacggcaat gagacgtgcc ggaaagggag ctccggcttt ttattacctg aattgcctat
5641 cattacagtg gtttcaccgt tgttaccgca atccagcccg cgcagaaaac ccatcatgtc
5701 aaagcgcatt ccttctgcag
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS ECOCYSJIHA 5720 bp ds-DNA BCT 14-MAY-1991
DEFINITION E.coli NADPH-sulfite reductase flavoprotein component (cysJ),
NADPH-sulfite reductase hemoprotein component (cysI), and 3'
phosphoadenosine 5'-phosphosulfate sulfotransferase (cysH) genes,
complete cds.
ACCESSION M23008 J05025 J05057 M27144
KEYWORDS flavoprotein; hemoprotein; sulfite reductase; sulfotransferase.
SOURCE E.coli (strain B, ATCC 11303) DNA, clone pJYW2.
ORGANISM Escherichia coli
Prokaryota; Bacteria; Gracilicutes; Scotobacteria;
Facultatively anaerobic rods; Enterobacteriaceae.
REFERENCE 1 (bases 1 to 324)
AUTHORS Ostrowski,J. and Kredich,N.M.
TITLE Molecular characterization of the cysJIH promoters of Salmonella
typhimurium and Escherichia coli: Regulation by cysB protein and
N-acetyl-L-serine
JOURNAL J. Bacteriol. 171, 130-140 (1989)
STANDARD simple staff_review
REFERENCE 2 (bases 2064 to 5720)
AUTHORS Ostrowski,J., Wu,J.-Y., Rueger,D.C., Miller,B.E., Siegel,L.M. and
Kredich,N.M.
TITLE Characterization of the cysJIH regions of Salmonella typhimurium
and Escherichia coli B: DNA sequences of cysI and cysH and a model
for the siroheme-Fe4S4 active center of sulfite reductase
hemoprotein based on amino acid homology with spinach nitrit
JOURNAL J. Biol. Chem. 264, 15726-15737 (1989)
STANDARD full staff_review
REFERENCE 3 (bases 265 to 2089)
AUTHORS Ostrowski,J., Barber,M.J., Rueger,D.C., Miller,B.E., Siegel,L.M.
and Kredich,N.M.
TITLE Characterization of the flavoprotein moieties of NADPH-sulfite
reductase from Salmonella typhimurium and Escherichia coli:
Physicochemical and catalytic properties, amino acid sequence
deduced from DNA sequence of cysJ and comparison with NADPH-cytoc
JOURNAL J. Biol. Chem. 264, 15796-15808 (1989)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for [J. Biol. Chem. 264,
15796-15808 (1989)] kindly submitted
by N.M.Kredich, 16-AUG-1989.
Draft entry and computer-readable copy of sequence [J. Biol. Chem.
264, 15726-15737 (1989)] kindly
submitted by N.M.Kredich, 16-AUG-1989.
FEATURES Location/Qualifiers
mRNA 219..>4610
CDS 285..2084
/EC_number="1.8.1.2"
/product="NADPH-sulfite reducatase flavoprotein component"
/gene="cysJ"
/codon_start=285
CDS 2084..3802
/EC_number="1.8.1.2"
/product="NADPH-sulfite reductase hemoprotein component"
/gene="cysI"
/codon_start=2084
repeat_region 3827..3856
/note="repetitive extragenic palindromic sequence"
CDS 3876..4610
/product="3' phosphoadenosine 5'-phosphosulfate
sulfotransferase"
/gene="cysH"
/codon_start=3876
terminator 4628..4661
BASE COUNT 1397 a 1464 c 1567 g 1292 t
ORIGIN
1 agtaccggaa aggctgtttt ttcgcattat ctaaaacgac tttagttgcg caaaatcgct
61 gatttatctt aatgattggc taaattcatt tgtttttcat taggttggtt aatctatttt
121 gttgttaaag actattgcta aaacaggtta gtcgatttgg ttattagtta tcgctatccc
181 gtctttaatc cacaccgttt gccccgttaa ccttaccttc tcttctgttt tatgggcgct
241 gacagggcgc agaaacagct ttgcttactg gaacataacg acgcatgacg acacaggtcc
301 caccttccgc gttgcttccg ttgaacccgg agcaactggc acgccttcag gcggccacga
361 ccgatttaac tcccacccag cttgcctggg tttctggcta tttctggggc gtactcaatc
421 agcagcctgc tgcgcttgca gcaacgccag cgccagctgc agaaatgccg ggtataacta
481 ttatctccgc ctcgcaaacc ggcaatgcgc gccgggttgc tgaagcatta cgtgatgatt
541 tattagcagc aaaactgaac gttaagctgg tgaacgcggg cgactataaa ttcaaacaaa
601 tcgccagcga aaaactgctc atcgtagtga cgtcaacgca aggggaaggg gaaccgccgg
661 aagaagccgt cgcgctgcat aagttcctgt tctccaaaaa agcgccaaag ctggaaaaca
721 ccgcgtttgc cgtgtttagc ctcggcgata cgtcttatga atttttctgc cagtccggga
781 aagatttcga cagcaagctg gcggaactgg gtggtgaacg cctgctcgac cgtgtcgatg
841 ccgatgttga ataccaggct gctgccagcg agtggcgcgc ccgcgtggtt gatgcgctta
901 aatcgcgtgc gcctgtcgcg gcaccttcgc aatccgtcgc tactggcgcg gtaaatgaaa
961 tccacaccag cccgtacagc aaagacgcgc cgctggtggc tagcctctct gttaaccaga
1021 aaattaccgg gcgtaactct gaaaaagacg ttcgccatat cgaaattgac ttaggtgact
1081 cgggcctgcg ttaccagccg ggtgacgcgc tgggcgtctg gtatcagaac gatccggcac
1141 tggtgaaaga acttgtcgaa ctgctgtggc tgaaaggcga tgaacctgtc accgtcgagg
1201 gcaaaacgtt gcctctgaac gaagcgctac agtggcactt cgaactgacc gtcaacaccg
1261 ccaacattgt tgagaattac gccacgctta cccgcagtga aacactgctg ccgctggtgg
1321 gcgataaagc gaagttacag cattacgccg cgacgacgcc gattgttgac atggtgcgtt
1381 tctccccggc acagcttgat gccgaagcgc taattaatct gctgcgcccg ctgacgccgc
1441 gtctctattc cattgcctcc tcgcaggcgg aagtcgagaa cgaagtacac gtcaccgttg
1501 gtgtggtgcg ttacgacgtg gaaggccgcg cccgtgccgg tggtgcctcc agcttcctcg
1561 ctgaccgcgt ggaagaagag ggcgaagtcc gcgtatttat cgaacataac gataacttcc
1621 gcctgccagc caatccagaa accccggtga ttatgattgg cccaggcacc ggcatcgcgc
1681 cgttccgcgc ctttatgcag caacgtgctg ccgatgaagc gccgggaaaa aactggctgt
1741 tctttggcaa cccgcacttt acggaagatt tcctctacca ggtggagtgg cagcgctacg
1801 tcaaagaggg tgtgctgacg cggatcgatc tcgcctggtc gcgcgaccaa aaagaaaaag
1861 tttacgtaca agacaaactg cgcgaacagg gcgcggagct gtggcgctgg atcaatgacg
1921 gtgcccacat ttatgtctgc ggtgacgcta atcgcatggc gaaagacgtt gagcaggcac
1981 ttctggaagt gattgccgaa tttggtggca tggacaccga agcggcggat gaatttttaa
2041 gtgagctgcg cgtagagcgc cgttatcagc gagatgtcta ctaatgagca tgagcgaaaa
2101 acatccaggg cctttagtgg tcgaaggaaa actgacagac gccgagcgca tgaagcttga
2161 aagcaactac ctgcgcggca ccattgcgga agatttaaac gacggtctga ccggcggctt
2221 taagggcgac aacttcctgc tgatccgctt ccacggcatg tatcagcagg atgaccgcga
2281 catccgcgcc gaacgtgctg aacagaagct ggagccgcgc cacgcgatgc tgttgcgctg
2341 ccgtctgccg ggtggggtga ttaccactaa acagtggcag gcgatagaca aatttgccgg
2401 tgaaaacacc atctatggca gcattcgcct gaccaaccgc cagacgtttc agttccacgg
2461 cattctgaaa aagaacgtca aaccggtgca ccagatgctg cactcggttg gtcttgatgc
2521 gctggcgacc gctaacgaca tgaaccgtaa cgtactctgc acctcgaacc cttacgagtc
2581 gcagctacac gcggaagcgt acgagtgggc gaagaagatt tctgagcatc tgctgccgcg
2641 tacccgcgcg tatgcggaga tctggctcga ccaggaaaaa gtcgccacta ctgatgaaga
2701 accgatcctc ggccagacct acctgccgcg taaattcaaa accacggtag tgatcccgcc
2761 acagaacgat atcgatctgc acgccaacga catgaacttc gtggcgatcg ccgaaaacgg
2821 caagctggtg ggctttaacc tgttggtggg cggtgggctt tccatcgaac acggcaacaa
2881 gaaaacctac gcccgcaccg cgagtgagtt tggctatctg ccgctggagc atacgctggc
2941 ggtggccgaa gccgtcgtga caactcaacg tgactggggt aaccgaaccg atcgtaaaaa
3001 tgccaaaacc aaatacacgc tggagcgcgt gggggttgag acgtttaaag cggaagtgga
3061 gcgtcgcgcg gggatcaaat ttgaaccgat ccgtccatat gagttcaccg gacgaggcga
3121 tcgtattggc tgggttaagg gcattgatga taactggcac ctgacgctgt ttatcgaaaa
3181 tggtcgcatc cttgattatc cggcgcgtcc gctgaaaacc ggcctgctgg agatcgcgaa
3241 gatccacaaa ggcgatttcc gcattacggc gaaccagaat ctgatcatcg ccggtgtacc
3301 ggaaagcgag aaagcgaaga tcgagaagat cgccaaagag agcgggttaa tgaatgccgt
3361 cacgccgcag cgtgaaaact caatggcctg cgtgtcattc ccgacttgcc cgctggcgat
3421 ggcggaagcg gagcgtttcc tgccgtcttt tatcgacaac atcgataatt taatggcgaa
3481 acatggtgtc agcgatgagc atatcgtgat gcgtgtaaca ggctgcccga acggttgtgg
3541 tcgcgcgatg ctggcggaag tgggcctggt gggtaaagcg ccgggtcgct acaacctgca
3601 tcttggcggc aaccgcattg ggacacgtat ccctcggatg tataaagaaa acatcaccga
3661 gccggaaatc ctggcgtcgc ttgatgaact gatagggcgc tgggcgaaag agcgcgaagc
3721 gggtgaaggc ttcggcgact ttacggtgcg tgcgggcatc attcgcccgg tgctcgatcc
3781 ggcgcgcgat ttgtgggatt aaccatcagc ccggtcttgt aggcctgata agacgcgtga
3841 gcgtcgcatc aggcaaggca aacagtgagg aatctatgtc caaactcgat ctaaacgccc
3901 tgaacgaact gccgaaggta gatcgcattc tggcgctggc ggaaactaac gcccaactgg
3961 aaaaactgga cgctgaaggc cgcgtagcct gggcgctgga taatctgccc ggtgaatatg
4021 tgctttcttc cagcttcggc attcaggcgg cggtgagcct gcatctggtg aatcagattc
4081 ggccggatat tccagtgatc ctcaccgata ccggttatct gtttccggaa acctaccgct
4141 ttattgacga gttaacggac aaactcaagc tcaacctgaa agtgtaccgt gctaccgaaa
4201 gcgccgcctg gcaggaagca cgctacggca aactgtggga acagggcgtt gaaggcattg
4261 aaaagtacaa tgacatcaac aaagtcgaac cgatgaaccg ggcgctgaaa gaacttaacg
4321 cgcaaacctg gtttgctggc ctgcgccgcg aacaatccgg cagccgcgcc aatttaccgg
4381 tgctggcaat tcagcgtggc gtatttaaag tgctgccgat tatcgactgg gataaccgaa
4441 ctatttatca gtacctgcaa aaacatggcc tgaaatatca cccattatgg gatgaaggat
4501 atttatcggt cggtgatacc catacaaccc gtaaatggga acctggcatg tcggaagaag
4561 aaacacgttt ctttggctta aaaagggaat gtggattgca cgaagggtaa atattgccgg
4621 ataaattaaa cgcctctgtc agaaatgatg ggggcgtttt tattttgcga gcagtattcc
4681 tgattttaaa cgtgaacgcc gctggaagaa ttatcaggta tagaatggcg tcgggtgctt
4741 gaggctgtct ggcgttaagc attcgcgagg ttccagatcc acaaaagccc caggcgatat
4801 ttctatcaac ctaggcttac gttcgaaccc aaacaattcg aatgttagtc tcttctttgc
4861 agggaggcaa gacatgctga caaaatatgc ccttgtggca atatagtgct gtgttttaca
4921 gtactgggat tcacgctgca tggtaggcca ctcgttgtgt gagttgagta tcagagaacg
4981 tggtatggag tttaaggcag ttctcgctta cgaatcgaag aagtagccca ccacgcgggg
5041 taaaacccat aagcgctaac ttaagggttg aaccatctga agaatgcgat gcctcggtgc
5101 ctcgttaaga cgatgcctcg cgttcttaat tgcgttttgt aggctgtcag ggatactgtc
5161 ccacgaatgg ccacctgtaa gctccaagat gaccattttt gttattctcc acaacgagtt
5221 agttcttctt ttcggatccg gcattctggg ggggaaatcc agcgaatggc tggattatgt
5281 cgtcaatttt ttgcggtgag tagtaatgca aatatccagc tttcgcgagt tcaggttctt
5341 tgctcgcaaa gcatccaggt gctgcaaact tttgagccgc ttaaaaagcc agttcaattt
5401 gccatcgcag acggtaacaa tcagccactt gctctgctga atattcatct tccggtaatg
5461 atgttagcaa tagcacatgg cccgctgctt ccagcgtttc cgcctgaact actcgtcctt
5521 ttcgacgatt ctcgctgagc agtcgggttt tactgattaa tgctttttcg ggaggaagtg
5581 atacggcaat gagacgtgcc ggaaagggag ctccggcttt ttattacctg aattgcctat
5641 cattacagtg gtttcaccgt tgttaccgca atccagcccg cgcagaaaac ccatcatgtc
5701 aaagcgcatt ccttctgcag
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