GenBank-Updates@genbank.bio.net (05/15/91)
LOCUS HUMANTLAA 1620 bp ss-mRNA PRI 15-MAY-1991
DEFINITION Human La protein mRNA, complete cds.
ACCESSION J04205 M11108
KEYWORDS La antigen; La protein; SS-B antigen; autoantigen.
SOURCE Human (adult) liver, cDNA to mRNA, clones lambda-La[2.1,26.2].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 223 to 391)
AUTHORS Chambers,J.C. and Keene,J.D.
TITLE Isolation and analysis of cDNA clones expressing human lupus La
antigen
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 82, 2115-2119 (1985)
STANDARD simple staff_review
REFERENCE 2 (bases 1 to 1620)
AUTHORS Chambers,J.C., Kenan,D., Martin,B.J. and Keene,J.D.
TITLE Genomic structure and amino acid sequence domains of the human La
autoantigen
JOURNAL J. Biol. Chem. 263, 18043-18051 (1989)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [J. Biol. Chem. 263,
18043-18051 (1989)] kindly provided
by J.D.Keene, 28-FEB-1989.
FEATURES Location/Qualifiers
mRNA <1..1620
/note="La autoantigen mRNA"
CDS 91..1317
/note="La autoantigen"
/product="La protein"
/codon_start=91
old_sequence (381.383)..(381.383)
/location=Proc. Natl. Acad. Sci. U.S.A. 82, 2115-2119
(1985) | 159..160
BASE COUNT 620 a 227 c 363 g 410 t
ORIGIN Chromosome 2.
1 ccggcggcgc tgggaggtgg agtcgttgct gttgctgttt gtgagcctgt ggcgcggctt
61 ctgtgggccg gaaccttaaa gatagccgta atggctgaaa atggtgataa tgaaaagatg
121 gctgccctgg aggccaaaat ctgtcatcaa attgagtatt attttggcga cttcaatttg
181 ccacgggaca agtttctaaa ggaacagata aaactggatg aaggctgggt acctttggag
241 ataatgataa aattcaacag gttgaaccgt ctaacaacag actttaatgt aattgtggaa
301 gcattgagca aatccaaggc agaactcatg gaaatcagtg aagataaaac taaaatcaga
361 aggtctccaa gcaaacccct acctgaagtg actgatgagt ataaaaatga tgtaaaaaac
421 agatctgttt atattaaagg cttcccaact gatgcaactc ttgatgacat aaaagaatgg
481 ttagaagata aaggtcaagt actaaatatt cagatgagaa gaacattgca taaagcattt
541 aagggatcaa tttttgttgt gtttgatagc attgaatctg ctaagaaatt tgtagagacc
601 cctggccaga agtacaaaga aacagacctg ctaatacttt tcaaggacga ttactttgcc
661 aaaaaaaatg aagaaagaaa acaaaataaa gtggaagcta aattaagagc taaacaggag
721 caagaagcaa aacaaaagtt agaagaagat gctgaaatga aatctctaga agaaaagatt
781 ggatgcttgc tgaaattttc gggtgattta gatgatcaga cctgtagaga agatttacac
841 atacttttct caaatcatgg tgaaataaaa tggatagact tcgtcagagg agcaaaagag
901 gggataattc tatttaaaga aaaagccaag gaagcattgg gtaaagccaa agatgcaaat
961 aatggtaacc tacaattaag gaacaaagaa gtgacttggg aagtactaga aggagaggtg
1021 gaaaaagaag cactgaagaa aataatagaa gaccaacaag aatccctaaa caaatggaag
1081 tcaaaaggtc gtagatttaa aggaaaagga aagggtaata aagctgccca gcctgggtct
1141 ggtaaaggaa aagtacagtt tcagggcaag aaaacgaaat ttgctagtga tgatgaacat
1201 gatgaacatg atgaaaatgg tgcaactgga cctgtgaaaa gagcaagaga agaaacagac
1261 aaagaagaac ctgcatccaa acaacagaaa acagaaaatg gtgctggaga ccagtagttt
1321 agtaaaccaa ttttttattc attttaaata ggttttaaac gacttttgtt tgcggggctt
1381 ttaaaaggaa aaccgaatta ggtccacttc aatgtccacc tgtgagaaag gaaaaatttt
1441 tttgttgttt aacttgtctt tttgttatgc aaatgagatt tctttgaatg tattgttctg
1501 tttgtgttat ttcagatgat tcaaatatca aaaggaagat tcttccatta aattgccttt
1561 gtaatatgag aatgtattag tacaaactaa ctaataaaat atatactata tgaaaagagc
//