GenBank-Updates@genbank.bio.net (05/16/91)
LOCUS HUMMHAAC 1098 bp ds-DNA PRI 16-MAY-1991
DEFINITION Human MHC class I HLA-A*2401 gene, complete cds.
ACCESSION M64742
KEYWORDS cell surface antigen; cell surface glycoprotein; class I gene;
integral membrane protein; major histocompatibility complex.
SOURCE Human EBV transformed B cell (SHJO and ELON cell line) DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1098)
AUTHORS Little,A.-M., Madrigal,J.A. and Parham,P.
TITLE Molecular definition of an elusive third HLA-A9 molecule - HLA-A9.3
JOURNAL Unpublished (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS join(1..73,74..343,344..619,620..895,896..1012,1013..1098)
/product="HLA-A protein"
/gene="HLA-A*2301"
/codon_start=1
exon 1..73
/number=1
/product="HLA-A protein"
/gene="HLA-A*2402"
exon 74..343
/number=2
/product="HLA-A protein"
/gene="HLA-A*2402"
exon 344..619
/number=3
/product="HLA-A protein"
/gene="HLA-A*2402"
exon 620..895
/number=4
/product="HLA-A protein"
/gene="HLA-A*2402"
exon 896..1012
/number=5
/product="HLA-A protein"
/gene="HLA-A*2402"
exon 1013..1098
/number=6-8
/product="HLA-A protein"
/gene="HLA-A*2402"
BASE COUNT 221 a 331 c 364 g 182 t
ORIGIN Chromosome 6.
1 atggccgtca tggcgccccg aaccctcgtc ctgctactct cgggggccct ggccctgacc
61 cagacctggg caggctccca ctccatgagg tatttctcca catccgtgtc ccggcccggc
121 cgcggggagc cccgcttcat cgccgtgggc tacgtggacg acacgcagtt cgtgcggttc
181 gacagcgacg ccgcgagcca gaggatggag ccgcgggcgc cgtggataga gcaggagggg
241 ccggagtatt gggacgagga gacagggaaa gtgaaggccc actcacagac tgaccgagag
301 aacctgcgga tcgcgctccg ctactacaac cagagcgagg ccggttctca caccctccag
361 atgatgtttg gctgcgacgt ggggtcggac gggcgcttcc tccgcgggta ccaccagtac
421 gcctacgacg gcaaggatta catcgccctg aaagaggacc tgcgctcttg gaccgcggcg
481 gacatggcgg ctcagatcac ccagcgcaag tgggaggcgg cccgtgtggc ggagcagttg
541 agagcctacc tggagggcac gtgcgtggac gggctccgca gatacctgga gaacgggaag
601 gagacgctgc agcgcacgga cccccccaag acacatatga cccaccaccc catctctgac
661 catgaggcca ctctgagatg ctgggccctg ggcttctacc ctgcggagat cacactgacc
721 tggcagcggg atggggagga ccagacccag gacacggagc ttgtggagac caggcctgca
781 ggggatggaa ccttccagaa gtgggcagct gtggtggtac cttctggaga ggagcagaga
841 tacacctgcc atgtgcagca tgagggtctg cccaagcccc tcaccctgag atgggagcca
901 tcttcccagc ccaccgtcca catcgtgggc atcattgctg gcctggttct ccttggagct
961 gtgatcactg gagctgtggt cgctgctgtg atgtggagga ggaacagctc agatagaaaa
1021 ggagggagct actctcaggc tgcaagcagt gacagtgccc agggctctga tgtgtctctc
1081 acagcttgta aagtgtga
//