GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS RATERK2 1467 bp ss-mRNA ROD 14-MAY-1991
DEFINITION Rat extracellular signal-related kinase (ERK2) mRNA, complete cds.
ACCESSION M64300
KEYWORDS extracellular signal-related kinase; protein kinase;
protein-serine/threonine kinase.
SOURCE Rat adult brain, cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Boulton,T.G., Nye,S.H., Robbins,D.J., Radziejewska,E.,
Panayotatos,N., Cobb,M.H. and Yancopoulos,G.D.
TITLE ERKs: A family of protein-serine/threonine kinases that are
activated and tyrosine phosphorylated in response to insulin and
NGF
JOURNAL Cell (1991) In press
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 172..1248
/note="presumed coding region"
/product="extracellular signal-related kinase 2"
/gene="ERK2"
/codon_start=172
BASE COUNT 365 a 382 c 355 g 365 t
ORIGIN
1 ccgtggttct accggcggtt agttctctct tctgtgttgt cctccctcct cgttcccgat
61 cgccgccagc cggctacacg ggcggcggcg cggttcctgt gggaagcgca gcacaagtcg
121 agcggtaacg cgaagcgtcg agcccaacgc ggcggaggct gtgcagccaa catggcggcg
181 gcggcggcgg cgggcccgga gatggtccgc gggcaggtgt tcgacgtggg gccgcgctac
241 actaatctct cgtacatcgg agaaggcgcc tacggcatgg tttgttctgc ttatgataat
301 ctcaacaaag ttcgagttgc tatcaagaaa atcagtcctt ttgagcacca gacctactgt
361 cagagaaccc tgagagagat aaaaatccta ctgcgcttca gacatgagaa catcatcggc
421 atcaatgaca tcatccgggc accaaccatt gagcagatga aagatgtata tatagtacag
481 gacctcatgg agacagatct ttacaagctc ttgaagacac agcacctcag caatgatcat
541 atctgctatt ttctttatca gatcctgaga ggattaaagt atatacattc agctaatgtt
601 ctgcaccgtg acctcaagcc ttccaacctc ctgctgaaca ccacttgtga tctcaagatc
661 tgtgactttg gccttgcccg tgttgcagat ccagaccatg atcatacagg gttcttgaca
721 gagtatgtag ccacgcgttg gtacagagct ccagaaatta tgttgaattc caagggttat
781 accaagtcca ttgatatttg gtctgtgggc tgcatcctgg cagagatgct atccaacagg
841 cctatcttcc caggaaagca ttaccttgac cagctgaatc acatcctggg tattcttgga
901 tctccatcac aggaagatct gaattgtata ataaatttaa aagctagaaa ctatttgctt
961 tctctcccgc acaaaaataa ggtgccgtgg aacaggttgt tcccaaacgc tgactccaaa
1021 gctctggatt tactggataa aatgttgaca tttaaccctc acaagaggat tgaagttgaa
1081 caggctctgg cccacccgta cctggagcag tattatgacc caagtgatga gcccattgct
1141 gaagcaccat tcaagtttga catggagctg gacgacttac ctaaggagaa gctcaaagaa
1201 ctcatttttg aagagactgc tcgattccag ccaggataca gatcttaaat tggtcaggac
1261 aagggctcag aggactggac gcgttcagat gtcggtgtcc ccccagttct tgaccctggt
1321 cctgtctcca gcccgtctca gcttacccac tcttgactcc tttgagccgt tccgaggggc
1381 agtctggtcg tagtggcttt tatactttca cggaattctt cagtccagag agttctcctg
1441 caccaggccc tgcacagttg cactcag
//GenBank-Updates@genbank.bio.net (05/14/91)
LOCUS RATERK3 3662 bp ss-mRNA ROD 14-MAY-1991
DEFINITION Rat extracellular signal-related kinase (ERK3) mRNA, complete cds.
ACCESSION M64301
KEYWORDS extracellular signal-related kinase; protein kinase;
protein-serine/threonine kinase.
SOURCE Rat adult brain, cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Boulton,T.G., Nye,S.H., Robbins,D.J., Radziejewska,E.,
Panayotatos,N., Cobb,M.H. and Yancopoulos,G.D.
TITLE ERKs: A family of protein-serine/threonine kinases that are
activated and tyrosine phosphorylated in response to insulin and
NGF
JOURNAL Cell (1991) In press
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 390..2021
/note="presumed coding region"
/product="extracellular signal-related kinase 3"
/gene="ERK3"
/codon_start=390
BASE COUNT 1006 a 785 c 849 g 1022 t
ORIGIN
1 agacctgccg ggcgcatatt tattcacagt tttgtcccat gttaagtcgg ttagcatagt
61 gaatctgagt gcatagtatg tcatttcatt ccgttgagtt tctcgagtgt tttctttaaa
121 tgtctgcaga gtcgctaccc ttccttgaac tatgaagcac tgcaatcttc ttaattctca
181 gtatgaagag agatttttga gctttaagtc tgaggggaac tcagcaggcc tggttggcgt
241 ctgcaatgaa catcaagaaa ccatcgtgct gtgggaatgt gatcgttttt ctcccttttt
301 gagagatctt tccttttgat gccagttttc ttccttgttt acacaagttc aacaatttga
361 aaggaaaagg caattgtaag ggttttaaaa tggcagagaa atttgaaagt ctcatgaaca
421 ttcatggctt tgatctgggt tccaggtaca tggacttaaa accattgggc tgtggaggca
481 atggcttggt tttttctgct gtagacaatg actgtgacaa aagagtagcc atcaagaaaa
541 ttgtcctcac cgatccccag agtgtcaaac atgccctccg tgaaatcaaa attattagaa
601 gacttgacca cgataacatt gtgaaagtgt ttgaaattct tggtcccagt ggaagccagc
661 tgacagacga tgtgggctct ctaacagagc tgaatagcgt ctacattgtt caggagtaca
721 tggagacaga cttggcgaac gtgctggagc agggcccttt actggaggag catgccaggc
781 tcttcatgta ccagctgctg cgtgggctca agtacatcca ctctgcaaac gtgctgcaca
841 gggatctcaa gccggccaac cttttcatta acactgaaga cttggtgctg aagattggtg
901 actttggcct ggcccggatc atggatcctc attattccca taagggtcat ctttctgaag
961 gattggttac caaatggtac agatctccac ggcttttact ttctcctaat aactatacta
1021 aagccattga catgtgggct gcaggctgca tctttgctga aatgctgact ggtaaaaccc
1081 tctttgcagg tgcacatgaa cttgaacaga tgcagctgat cttggagtct atccctgttg
1141 tgcacgagga agatcggcag gagcttctca gcgtgattcc agtttacatt agaaacgaca
1201 tgactgagcc acacaaaccg ctgactcagc tgcttccggg gattagtcgg gaagcactgg
1261 atttcctgga acagattctg acgttcagtc ccatggaccg gctgacagcc gaggaagcac
1321 tttcccatcc ttacatgagc atctactctt tcccaacgga cgagcctatt tccagccatc
1381 ctttccacat agaagacgaa gtggacgaca ttttgctaat ggatgaaaca cacagtcaca
1441 tttataactg ggaaaggtac cacgattgtc agttctcgga gcatgactgg cctattcata
1501 acaactttga tatcgatgag gttcagcttg acccgagagc tctgtctgat gtcaccgatg
1561 aagaagaagt tcaagttgat cctcgaaagt acttggatgg agaccgagag aagtatctgg
1621 aggatcccgc cttcgacacc agctactctg ctgagccttg ctggcagtac ccagatcacc
1681 acgagaacaa gtactgtgat ctggagtgta gccacacctg taactacaaa acaaggtcgc
1741 catcatactt agataacctg gtgtggaggg agagcgaggt taaccattac tatgagccca
1801 agcttattat agatctttcc aactggaaag agcaaagtaa ggacaaatcc gacaagagag
1861 gcaagtccaa gtgtgagagg aacgggttgg tcaagcgcag attgcgcttg aggaagcgtc
1921 ccagcagctg gctgagaggg agaggggcca aggctttgac tttgatgcct tcatcgcagg
1981 caccgttcag ctcagtgccc agcgtgagtc tgctgacgta gttgacaagt taaacgactt
2041 gaatagctca gtgtcccagc tagaaatgaa aagcctgata tccaagtcag tcagccgaga
2101 aaagcaagaa aagggaaggg ctaacctggc ccagctggga gccttgtacc agccctcctg
2161 ggagagccag tttgtgagtg gcggggagga gtgcttcctt atcagtcagt tttgttgtga
2221 ggtcaggaag gacgaacacg tggagaagga gaacacttac accagctatt tggacaagtt
2281 ttttagcagg aaggaggatt ctgaaatgct agaaactgag ccagtggaag aagggaagcg
2341 tggggagaga ggccgtgagg cagggcttct gagcagcggt ggggagtttc tcctgagcag
2401 gcagctagag tccataggca ccccgcagtt ccacagtcca gggggatccc cactcaagtc
2461 catccaggcc acgttaacac cttccgctat gaaatcttcc cctcaaatcc ctcacaagac
2521 atacagcaac attctgaaac atctgaacta aacactcagc agacacttct tttgttcttc
2581 atgaaatgtg ttgtgtcttt tttatcacta atgttttaag tcattttttt tttacttgaa
2641 tcagaaggtg tcattaattt gcaaggattt ttcttggttc tcagtttgta aaacacagag
2701 ttttttctac atgtgagtta gttttcattt gaactggcat gtcgtttgca cacacacaaa
2761 gaatagagca aaacaatgca gtgcaggagg agacaagatg cgctaggatg gacagacatt
2821 ctcacagacc agtgacctgc ttacaggaaa caaaaccttg ccttgaaact tacacagtga
2881 gactgtacat aattgcatga aaagatctat ttttttcctg aaacattttt cattcattag
2941 tattttcaag tttttcatac tgtacacatt tcttaagaca catgatacca gcagcaactg
3001 aaaacgaatg ccgaatttgg tacacatgtg ttatctacct caaggtaaca aaagtatgcg
3061 ggcgaaacct aacccaccca tagtcgtccg cggcatatgc acttgtatct agccagcgtt
3121 ggccgcagta accaatgaga ctcgtccgcc atttatcaat gtcctggtgt tcatccttta
3181 cagtgaagtg ttagatacat cacatcttat ttatttttag caaatcagta tattttctgt
3241 atttaattat aaaaggtaac ttagtttaag tttatttgca actgcccttc ttcccgtttg
3301 gcactatggt ttgttgcctg ccgagctgat ctgagaagtc agcttgtccc gaggctgtcc
3361 atgtacgtta agtaaagtgc tcactgtgta taggaatctg tattttggag gtgcttgatc
3421 tatctacaaa gaaaaaaatt aggaatttat tataaaatgc tcctagaagt cttaatggtg
3481 tttatttttt aaaaccttgt aatgttagac ttgtgtgcat ggaagtgatt aaggtacatc
3541 attattgtag tttgaacatt gtacatgata agccttcccc cacccccgtt tttactgtat
3601 gtttttattg aatgatctat tccccatccc taggcaagca tgaataaaat taggttaaat
3661 gt
//GenBank-Updates@genbank.bio.net (05/17/91)
LOCUS RATERK2 1467 bp ss-mRNA ROD 17-MAY-1991
DEFINITION Rat extracellular signal-related kinase (ERK2) mRNA, complete cds.
ACCESSION M64300
KEYWORDS extracellular signal-related kinase; protein kinase;
protein-serine/threonine kinase.
SOURCE Rat adult brain, cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Boulton,T.G., Nye,S.H., Robbins,D.J., Radziejewska,E.,
Panayotatos,N., Cobb,M.H. and Yancopoulos,G.D.
TITLE ERKs: A family of protein-serine/threonine kinases that are
activated and tyrosine phosphorylated in response to insulin and
NGF
JOURNAL Cell 65, 663-675 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 172..1248
/note="presumed coding region"
/product="extracellular signal-related kinase 2"
/gene="ERK2"
/codon_start=172
BASE COUNT 365 a 382 c 355 g 365 t
ORIGIN
1 ccgtggttct accggcggtt agttctctct tctgtgttgt cctccctcct cgttcccgat
61 cgccgccagc cggctacacg ggcggcggcg cggttcctgt gggaagcgca gcacaagtcg
121 agcggtaacg cgaagcgtcg agcccaacgc ggcggaggct gtgcagccaa catggcggcg
181 gcggcggcgg cgggcccgga gatggtccgc gggcaggtgt tcgacgtggg gccgcgctac
241 actaatctct cgtacatcgg agaaggcgcc tacggcatgg tttgttctgc ttatgataat
301 ctcaacaaag ttcgagttgc tatcaagaaa atcagtcctt ttgagcacca gacctactgt
361 cagagaaccc tgagagagat aaaaatccta ctgcgcttca gacatgagaa catcatcggc
421 atcaatgaca tcatccgggc accaaccatt gagcagatga aagatgtata tatagtacag
481 gacctcatgg agacagatct ttacaagctc ttgaagacac agcacctcag caatgatcat
541 atctgctatt ttctttatca gatcctgaga ggattaaagt atatacattc agctaatgtt
601 ctgcaccgtg acctcaagcc ttccaacctc ctgctgaaca ccacttgtga tctcaagatc
661 tgtgactttg gccttgcccg tgttgcagat ccagaccatg atcatacagg gttcttgaca
721 gagtatgtag ccacgcgttg gtacagagct ccagaaatta tgttgaattc caagggttat
781 accaagtcca ttgatatttg gtctgtgggc tgcatcctgg cagagatgct atccaacagg
841 cctatcttcc caggaaagca ttaccttgac cagctgaatc acatcctggg tattcttgga
901 tctccatcac aggaagatct gaattgtata ataaatttaa aagctagaaa ctatttgctt
961 tctctcccgc acaaaaataa ggtgccgtgg aacaggttgt tcccaaacgc tgactccaaa
1021 gctctggatt tactggataa aatgttgaca tttaaccctc acaagaggat tgaagttgaa
1081 caggctctgg cccacccgta cctggagcag tattatgacc caagtgatga gcccattgct
1141 gaagcaccat tcaagtttga catggagctg gacgacttac ctaaggagaa gctcaaagaa
1201 ctcatttttg aagagactgc tcgattccag ccaggataca gatcttaaat tggtcaggac
1261 aagggctcag aggactggac gcgttcagat gtcggtgtcc ccccagttct tgaccctggt
1321 cctgtctcca gcccgtctca gcttacccac tcttgactcc tttgagccgt tccgaggggc
1381 agtctggtcg tagtggcttt tatactttca cggaattctt cagtccagag agttctcctg
1441 caccaggccc tgcacagttg cactcag
//GenBank-Updates@genbank.bio.net (05/17/91)
LOCUS RATERK3 3662 bp ss-mRNA ROD 17-MAY-1991
DEFINITION Rat extracellular signal-related kinase (ERK3) mRNA, complete cds.
ACCESSION M64301
KEYWORDS extracellular signal-related kinase; protein kinase;
protein-serine/threonine kinase.
SOURCE Rat adult brain, cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Boulton,T.G., Nye,S.H., Robbins,D.J., Radziejewska,E.,
Panayotatos,N., Cobb,M.H. and Yancopoulos,G.D.
TITLE ERKs: A family of protein-serine/threonine kinases that are
activated and tyrosine phosphorylated in response to insulin and
NGF
JOURNAL Cell 65, 663-675 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 390..2021
/note="presumed coding region"
/product="extracellular signal-related kinase 3"
/gene="ERK3"
/codon_start=390
BASE COUNT 1006 a 785 c 849 g 1022 t
ORIGIN
1 agacctgccg ggcgcatatt tattcacagt tttgtcccat gttaagtcgg ttagcatagt
61 gaatctgagt gcatagtatg tcatttcatt ccgttgagtt tctcgagtgt tttctttaaa
121 tgtctgcaga gtcgctaccc ttccttgaac tatgaagcac tgcaatcttc ttaattctca
181 gtatgaagag agatttttga gctttaagtc tgaggggaac tcagcaggcc tggttggcgt
241 ctgcaatgaa catcaagaaa ccatcgtgct gtgggaatgt gatcgttttt ctcccttttt
301 gagagatctt tccttttgat gccagttttc ttccttgttt acacaagttc aacaatttga
361 aaggaaaagg caattgtaag ggttttaaaa tggcagagaa atttgaaagt ctcatgaaca
421 ttcatggctt tgatctgggt tccaggtaca tggacttaaa accattgggc tgtggaggca
481 atggcttggt tttttctgct gtagacaatg actgtgacaa aagagtagcc atcaagaaaa
541 ttgtcctcac cgatccccag agtgtcaaac atgccctccg tgaaatcaaa attattagaa
601 gacttgacca cgataacatt gtgaaagtgt ttgaaattct tggtcccagt ggaagccagc
661 tgacagacga tgtgggctct ctaacagagc tgaatagcgt ctacattgtt caggagtaca
721 tggagacaga cttggcgaac gtgctggagc agggcccttt actggaggag catgccaggc
781 tcttcatgta ccagctgctg cgtgggctca agtacatcca ctctgcaaac gtgctgcaca
841 gggatctcaa gccggccaac cttttcatta acactgaaga cttggtgctg aagattggtg
901 actttggcct ggcccggatc atggatcctc attattccca taagggtcat ctttctgaag
961 gattggttac caaatggtac agatctccac ggcttttact ttctcctaat aactatacta
1021 aagccattga catgtgggct gcaggctgca tctttgctga aatgctgact ggtaaaaccc
1081 tctttgcagg tgcacatgaa cttgaacaga tgcagctgat cttggagtct atccctgttg
1141 tgcacgagga agatcggcag gagcttctca gcgtgattcc agtttacatt agaaacgaca
1201 tgactgagcc acacaaaccg ctgactcagc tgcttccggg gattagtcgg gaagcactgg
1261 atttcctgga acagattctg acgttcagtc ccatggaccg gctgacagcc gaggaagcac
1321 tttcccatcc ttacatgagc atctactctt tcccaacgga cgagcctatt tccagccatc
1381 ctttccacat agaagacgaa gtggacgaca ttttgctaat ggatgaaaca cacagtcaca
1441 tttataactg ggaaaggtac cacgattgtc agttctcgga gcatgactgg cctattcata
1501 acaactttga tatcgatgag gttcagcttg acccgagagc tctgtctgat gtcaccgatg
1561 aagaagaagt tcaagttgat cctcgaaagt acttggatgg agaccgagag aagtatctgg
1621 aggatcccgc cttcgacacc agctactctg ctgagccttg ctggcagtac ccagatcacc
1681 acgagaacaa gtactgtgat ctggagtgta gccacacctg taactacaaa acaaggtcgc
1741 catcatactt agataacctg gtgtggaggg agagcgaggt taaccattac tatgagccca
1801 agcttattat agatctttcc aactggaaag agcaaagtaa ggacaaatcc gacaagagag
1861 gcaagtccaa gtgtgagagg aacgggttgg tcaagcgcag attgcgcttg aggaagcgtc
1921 ccagcagctg gctgagaggg agaggggcca aggctttgac tttgatgcct tcatcgcagg
1981 caccgttcag ctcagtgccc agcgtgagtc tgctgacgta gttgacaagt taaacgactt
2041 gaatagctca gtgtcccagc tagaaatgaa aagcctgata tccaagtcag tcagccgaga
2101 aaagcaagaa aagggaaggg ctaacctggc ccagctggga gccttgtacc agccctcctg
2161 ggagagccag tttgtgagtg gcggggagga gtgcttcctt atcagtcagt tttgttgtga
2221 ggtcaggaag gacgaacacg tggagaagga gaacacttac accagctatt tggacaagtt
2281 ttttagcagg aaggaggatt ctgaaatgct agaaactgag ccagtggaag aagggaagcg
2341 tggggagaga ggccgtgagg cagggcttct gagcagcggt ggggagtttc tcctgagcag
2401 gcagctagag tccataggca ccccgcagtt ccacagtcca gggggatccc cactcaagtc
2461 catccaggcc acgttaacac cttccgctat gaaatcttcc cctcaaatcc ctcacaagac
2521 atacagcaac attctgaaac atctgaacta aacactcagc agacacttct tttgttcttc
2581 atgaaatgtg ttgtgtcttt tttatcacta atgttttaag tcattttttt tttacttgaa
2641 tcagaaggtg tcattaattt gcaaggattt ttcttggttc tcagtttgta aaacacagag
2701 ttttttctac atgtgagtta gttttcattt gaactggcat gtcgtttgca cacacacaaa
2761 gaatagagca aaacaatgca gtgcaggagg agacaagatg cgctaggatg gacagacatt
2821 ctcacagacc agtgacctgc ttacaggaaa caaaaccttg ccttgaaact tacacagtga
2881 gactgtacat aattgcatga aaagatctat ttttttcctg aaacattttt cattcattag
2941 tattttcaag tttttcatac tgtacacatt tcttaagaca catgatacca gcagcaactg
3001 aaaacgaatg ccgaatttgg tacacatgtg ttatctacct caaggtaaca aaagtatgcg
3061 ggcgaaacct aacccaccca tagtcgtccg cggcatatgc acttgtatct agccagcgtt
3121 ggccgcagta accaatgaga ctcgtccgcc atttatcaat gtcctggtgt tcatccttta
3181 cagtgaagtg ttagatacat cacatcttat ttatttttag caaatcagta tattttctgt
3241 atttaattat aaaaggtaac ttagtttaag tttatttgca actgcccttc ttcccgtttg
3301 gcactatggt ttgttgcctg ccgagctgat ctgagaagtc agcttgtccc gaggctgtcc
3361 atgtacgtta agtaaagtgc tcactgtgta taggaatctg tattttggag gtgcttgatc
3421 tatctacaaa gaaaaaaatt aggaatttat tataaaatgc tcctagaagt cttaatggtg
3481 tttatttttt aaaaccttgt aatgttagac ttgtgtgcat ggaagtgatt aaggtacatc
3541 attattgtag tttgaacatt gtacatgata agccttcccc cacccccgtt tttactgtat
3601 gtttttattg aatgatctat tccccatccc taggcaagca tgaataaaat taggttaaat
3661 gt
//