GenBank-Updates@genbank.bio.net (05/17/91)
LOCUS ASNAREA 4986 bp ds-DNA PLN 17-MAY-1991
DEFINITION Aspergillus nidulans areA gene for DNA-binding protein
ACCESSION X52491
KEYWORDS areA gene; dna binding protein; zinc finger protein.
SOURCE Aspergillus nidulans DNA.
ORGANISM Aspergillus nidulans
Eukaryota; Plantae; Thallobionta; Eumycota; Ascomycotina;
Plectomycetes; Eurotiales; Trichocomaceae.
REFERENCE 1 (bases 1 to 4986)
AUTHORS Arst,J.H.N.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 4986)
AUTHORS Kudla,B., Caddick,M.X., Langdon,T., Martinez-Rossi,N.M.,
Bennett,C.F., Sibley,S., Davies,R.W. and Arst,J.H.N.
TITLE The regulatory gene areA mediating nitrogen metabolite repression
in Aspergillus nidulans. Mutations affecting specificity of gene
activation alter a loop residue of a putative zinc finger.
JOURNAL EMBO J. 9, 1355-1364 (1990)
STANDARD full automatic
REFERENCE 3 (bases 1 to 4986)
AUTHORS Caddick,M.X. and Arst,H.N.
TITLE Nitrogen regulation in Aspergillus: are two fingers better than
one?
JOURNAL Gene 95, 123-127 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17429; AREA$ASPNI.
From EMBL 26 entry ANAREA; dated 21-JAN-1991.
FEATURES Location/Qualifiers
promoter 1685..1689
/note="put. CAAT box"
misc_feature 1702..1709
/note="put. heat shock consensus"
misc_feature 1843..1861
/note="pyrimidine-rich region"
promoter 1872..1875
/note="put. TATA box"
precursor_RNA 1875..4606
/note="primary transcript"
CDS 1908..4064
/note="areA gene product (AA 1-719)"
/codon_start=1908
misc_feature 4282..4302
/note="7bp contiguous direct repeats"
polyA_site 4582..4587
/note="put. polyA signal"
BASE COUNT 1130 a 1443 c 1184 g 1229 t
ORIGIN
1 ggtaccacca ctagcagggg taaggctggg tactttctgg tactttgaat cgacagcgga
61 acaccagaac accaagatgg tcgtgtacgg ctacggagta cagatgtgcg gagaacggac
121 ccagatacaa gcacaaggta ctgcgagttg ccaacgacct agacgattta gacgacctag
181 actatatccg gtctccaatt ggagacggtc tgggtatata ataagctcgc attaaagtgg
241 aatcgaaccc taaggcgtcc actcgagtcc tctccatccg ggacgaacct tacaagcgtc
301 cggtcgcgac cgcggtattt gtattacact tacatgtttc acacggatat attttgtcaa
361 tgatgtattg aggtcacttc agtggtttca gtcttcacaa tcttcgcgag aaaaagggta
421 aatgtgtact cgatatgtag agacagacaa gttcatcgat ggatctatta aggacaaatc
481 aagcgtctgc ttcagcatta gcttggtgtc ggtgcgcact aaaaaaaaaa aaaaagaccg
541 tctggacaag agaagaatcc ggagtccagt aatgcaacca gctgctagta ctgacatggt
601 ctttctatta ttgtctatta ctgaatcata atcatctgtt atcatctgaa tgtgatcctc
661 tggctggccg ctgatcaacc actcaccact gctatcatcc atcctctgac ttgcttccta
721 attcccttgt taccttcacc ccgtagtata gactacccct tctctcattc ttgtcccgtc
781 tcgctgcctc gcgcaaattg cgatcggttg attcaaatac atcgcaagcc caatgcgcta
841 ccgtctgtat ctacaggagc cttgttcggc ggtcccggca caccaacgcc agagctggag
901 ctcgatccca tcctgcaacc cccaccagaa gataaagaag aaaggcacag atcagaagct
961 gatcagaggc ccgagctgaa gcaactgccg agatatacga ccagaattat ccaaactcac
1021 cgtgctgctg gaccagaact ggggtatgca tcctttctga aagggttgtt atccggccgt
1081 attaatatta atcatcgtga tctcagaccc gatcctagct tccgctcctg caccttcttc
1141 gcttcttccc tgcatcctcg accttgcaac gcttggagcc ggccttctgg tcgtcaacgg
1201 cgggtaagct gaatttattc ctctccaggc tgtccgagct gtccaggctg actttcctcc
1261 gcaaaggggc caattactgt ggttccattc cccctccatt ccttccatct cactcctctc
1321 gtcgctctta tctaccacca tccccttccc tgtcctatct atctcgcttc cttacctggc
1381 ctctcccctt atctattctt ttcttctgcc tcgtggcctt ccaattagag gagccacgag
1441 atctccagcc cacggtcatg tctgggttga ctctcggggg tggttctggc cgtgtgcgac
1501 cgacacaagc cgctgccgct tttcccacct cgcatgattt cgccgaccct gatcgctcgt
1561 ccgtcgcccg caatgccaac cggccctccc gccgtttcgc tgcacctccg cagctgtccg
1621 acgacttctc gctcgagggg tcgacagccc tgatgagatg cagaagaagg atccgttagc
1681 gactcaaata tggaagctct attctagaac gaaagctcag ttgcccaacc aagagcgcat
1741 ggaaaatttg acctggcgga tgatggctct gagtctgagg cgtcaggaaa gagagcgcgc
1801 ccagcagcaa gcccggtacg tcatcattcc cgatcggggg tatttctttt ctctttctct
1861 tgctgatctt ctatagtgcc tccagccaaa agagtcctgt tcctggcatg agtggcatcg
1921 ctcagctccg tctgtctgat cgtgtttcca ataccccgac cacaactgca gatactgtct
1981 cagatgctat gaaccttgac gacttcatca tccctttctc tccgtctgac cacccatctc
2041 cctccacaac gaaagcctcc gaagccacta ctggtgctat acctatcaaa gcccgcaggg
2101 atcagtccgc gtcggaagcc accccagtac ctgcatcttt ccctcacccg gcccaggatc
2161 agcggaggga gagtgagttc ggatacgtac cgcgtagagt gcgcaagacg agcatcgatg
2221 agcgtcaatt cttcaacctg cagattccgt cccgcaagcg gccggccgag tcctcgcctc
2281 acgtaccgcc tgtgtccacc agcatgctag ctcatgaccc ggatttctca catgctgtac
2341 cggagtatac cttggatact tcgcatggac tgtctctaca gaatcagatg aacgctcagc
2401 agctcgccaa tgctcagaac cacacctccc ccaatatggc gttcgctctg gatactttca
2461 acctgggcga cgatcctatc cttccatctg ctggtcctta ccagcagcaa ttcactttct
2521 cgcccagcga gtcaccgatg accagcggta acccgtttgc caacctctac gctcagactc
2581 cgattgcctc ttcactcaac tcaaccgact tcttctctcc tccgccgtcc ggctatcagt
2641 cgactgcttc gactcctcag cctgcgtatg atggcgaaca ctccaagtat tttgatatgc
2701 ccgtcgacgc gcggtcgcaa cgccgggttg ttcccgctta cattactcag cgatcatcga
2761 atttgtctgc ctcgctgcaa cctcgatata tgtacaacca gggtggttcg tcccaggata
2821 ttacacagca gaatgcccat atgggggccc agtcttcatc catgcaatcc cctggctttt
2881 ctatcccgca gcatgttgat ccaacgcaag tgttgaatcc gaacgagttt aacggtaacc
2941 acgccgcaat gttcagtttc ggcgccgact cggatgttga agatgacgat gggaaccaat
3001 tttcggccgg aggactggca atgccagccg agttcggcga cgacagtatc agtgacatga
3061 atagcaacat ggcgtgggag acatcatatc ccaactcttt ccagtcgctg cctgcttttg
3121 ctgcacagca ccgaaagcat gttaccatcg ggtctgcgga catgatggat accccgagcg
3181 agtggaacca gggcggaagc ctaggtcgaa ctcacgagtc ggctgcgtca gtcagcgagg
3241 tgcgcaatcg ggatcaagac cctcgacggc agaagatcgc tcgcacctcg tccactccaa
3301 acacagccca actactacgc cagagcatgc agaaccaatc gtcccacacg tctcccaaca
3361 ctccgcccga gtcgggtcta aacagcgctg ctccatcgcg gcccgccagt ccaggcggga
3421 ccaagaacgg agagcagaat ggtcccacca cctgcacgaa ctgctttacg cagaccacac
3481 cgctgtggcg gcgtaaccct gaaggtcagc cgctgtgcaa cgcctgcggt ttgtttttga
3541 agttgcacgg cgtggtgcgc ccactgtcgc tcaagaccga tgtgatcaag aagcgtaacc
3601 gcaacagcgc caatagcctt gccgttggct cttcacgggt atccaaaaag tcagcccgca
3661 agaactcggt tcagcaggta actccgactg cgcctacctc gagccgggcc caaagcaata
3721 cgacatccga gtctccccca gcaatgccgg gtagctccgg ccgaggctct ggagtcgttc
3781 ctattgcggc tgccccgcct aaatctagct cagcggcgac tacgtctccg ggcacaaaca
3841 acggttgtgg tgcggtacag gtggctccta aacgtcagcg taggctggaa aaggcctctg
3901 atgttgatat ggcggaaagc ccgtccagta cctcgtccgg tggacgatcc aaggttgttc
3961 cattggcgcc ggctatgcct ccagcggccg tcaacccagc caaccacagt atcgctgctg
4021 gtcagggcgc aagccaggaa tgggagtggt tgacgatgag tttgtaggct tctaaagggg
4081 ccaactcacg tgtgtgatct ctttcctaac ccttttcttt tgcgatgata ttttatacga
4141 catagacctg atgactacca ctgagctggg tttctcgctg gagcaggcgt ttggtgatcg
4201 agcgggacag ccggtcaaat ggcttcacga tgctaattga tggttacgag tgacgcgctt
4261 tcggttcggt ttcgtctatg gtctacggtc tacggtctac ggttctcggt cttcgtcttt
4321 gtcttcggtt cttcgggtct tatttacgtc ttaatctgac tgacgattcg agatatgcaa
4381 cgtttgtcag gatcgtcacg tctatgtttt gtgcttgact tgtgattttt gcttgataca
4441 accgcgtctg tccggtacct ggccttcgtc tgtccggtac ctggccttcg tctgcttttt
4501 ttgtttgtgt ttcatgtgtt atgtttgttg ttgcattcga ggtcaggccg ggcagaagtg
4561 cgcatctcct tgctttagtc taatagatta tgatgtttat gtatcgatca tcctctgaat
4621 caatagtact gtgtagtttt gtaggactgg cggcagatgc ttagtcatgt gggtcacgtg
4681 acagtataaa aatttccggc atctcaaact gaagaaatca ttgacctacc aacacaaaat
4741 tcaagtacgc tttaatagaa caatcagctc cataaccatt atattggtct attatacgtg
4801 aatctgcgga gtttgtggat tttagctaac agaaatactc agaaaagcta gccaaaatgg
4861 gcgccagcac caagagaaag aaggagaaac agaaggactt ccaggtacgt tgtgttaccc
4921 atctatggaa ctcgtttcta acgcacccga gaaaccaaag ttgaaggtcg gcaaggcaaa
4981 ggccaa
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