GenBank-Updates@genbank.bio.net (05/17/91)
LOCUS YSCTHR2 3140 bp ds-DNA PLN 17-MAY-1991
DEFINITION Yeast THR1 gene for homoserine kinase (EC 2.7.1.39)
ACCESSION X52901
KEYWORDS THR1 gene; homoserine kinase.
SOURCE Saccharomyces cerevisiae DNA.
ORGANISM Saccharomyces cerevisiae
Eukaryota; Plantae; Thallobionta; Eumycota; Hemiascomycetes;
Endomycetales; Saccharomycetaceae.
REFERENCE 1 (bases 1 to 3140)
AUTHORS Feldmann,H.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 3140)
AUTHORS Mannhaupt,G., Pohlenz,H.D., Seefluth,A.K., Pilz,U. and Feldmann,H.
TITLE Yeast homoserine kinase. Characteristics of the correspondig gene,
THR1, and the purified enzyme, and evolutionary relationships with
other enzymes of threonine metabolism
JOURNAL Eur. J. Biochem. 191, 115-122 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17423; KHSE$YEAST.
**map: chromosome=chromosome VIII; For E.coli homoserine kinase and
Brevibacterium lactofermentum homoserine kinase see <J01706> and
<Y00140>.
Data kindly reviewed (06-JUL-1990) by Feldmann H.
From EMBL 26 entry SCTHR1; dated 12-SEP-1990.
FEATURES Location/Qualifiers
promoter 1306..1314
/note="put. TATA box"
promoter 1370..1377
/note="put. TATA box"
promoter 1394..1401
/note="put. TATA box"
precursor_RNA 1471..3112
/note="primary transcript"
precursor_RNA 1519..3112
/note="alt. primary transcript"
CDS 1609..2676
/note="homoserine kinase (AA 1-356)"
/codon_start=1609
misc_feature 2803..2813
/note="polyA signal"
BASE COUNT 866 a 741 c 617 g 916 t
ORIGIN
1 ggatcctctg tctccttgca ttacaacagt agctctaccc ttaccattgc cagcattatt
61 tacatttccc gtaaatatca tttcggcaac acgtgagata tcatctggct tcaaatcttc
121 gatcttactt atcatttcgt tgactgggat tttgcgacca tgcatgagaa cttgtctgcc
181 catatcttcc aattctacca gtttagactc taggttcatt agtagtgaag acttcaactg
241 attcttggcc ctggagactt cgtcttcagt taacctcaaa tccttattag caaatgtatt
301 atacatttgc tgtgcaatta cctcaaccgc ttgaggagct gctgcggtat acaagataat
361 gaaataccga aaataccaga atccgaataa gaatggttga acgcaacaca attttcaaca
421 aagtaatact ggttcaaaac gtgggtatac aaacgagaat acatcccctt tcctggccca
481 ccagcactga aagaaccacc acctccaagt aaagtttgta atgtcttgaa agcataaatg
541 tctggatgat tatagggaga cctatcaaat ccgatctggc cgatctggat gtggaataat
601 tctggtaaat tcccaaacac tggtgctggt ggaatacaac tttccccgcc cgtatattgg
661 gcaacttttt tggtgatcga gggtgtgtag attgccagtc accgagatac ttttctgtaa
721 gctctaatgc cttttcgtga ggaacaccaa caaatgccgc aacagtattt tctggggtgt
781 agaatttatt tctgtagtcc aataagtagt atttagaaat agaaggaatg agctctctag
841 ggcagattaa aggggacccc aaagtttctc cggagtatgc tgctgtgtgc aacagctcag
901 gtaataccaa ttctggcttc atccaaactt catcgatttc atactctgcc gacagcttct
961 gttcttgcag ttcttgctca gtaatcttag ggaacctcac agtttctgac attaattgaa
1021 gcattttacc cacatcctgg ttgaacacag aagcctgata catcaaattt tctctagacg
1081 aggtacactg gtaattccca cccagtaact ccaacgtctc tgccattgct cggccctcga
1141 cgtgttcggt tgatttgaat gctagtctat ccaagatatg tgtacaaccc ttcaaattcc
1201 taccttcaaa ccgtgatcct gcgtcgatgt ataggcctaa ggcactaaag tgtccaggag
1261 tatttgatgt cgccactttc agtccattcg ctagtgacga aagcttaaaa ttatcggttc
1321 tagcgatgtt agagtacaac ctctgaacgc cgttccttag catcttttgt tattaatcag
1381 ctctctgctt tgcattaatt tgaccacctg ccctgaaaca cctttcttct agtccacctg
1441 tgtaggcttt ttcacctgaa ttgttcattc tcgatacgcc ctcacgccgg atgaaaaatt
1501 tgtgcaagag tcatcatctc gaaaagatat ggtgataaaa acaagtgtac ttctaacctg
1561 cctaatggtt ataacagtag cataaagtag atatacggac tacagaaaat ggttcgtgcc
1621 ttcaaaatta aagttccagc ttcttccgcc aatatcggcc ctggttatga tgttcttggt
1681 gtcggtcttt ctctattctt ggagttagat gtcaccatcg actccagcca agctcaggaa
1741 acaaacgacg atcccaacaa ctgcaagctg tcttacacta aagaaagtga aggctattct
1801 acggtcccat tgcgttctga tgctaacctg attaccagga ctgcgttata tgtgttgcgt
1861 tgcaatatta gaaacttccc ctccggaacc aaagttcacg tctccaaccc aatcccactt
1921 ggccgtggat tgggttcctc tggtgcagca gttgtggcag gtgttatttt aggtaacgaa
1981 gtggcccaat tgggtttctc taagcaacgt atgttggact actgtttgat gattgaacgt
2041 catccagaca acataaccgc tgctatgatg ggaggctttt gcggttcatt cctaagggac
2101 ttgaccccac aagaggtgga aagacgtgag attccattgg ctgaggtgct tccagaacct
2161 tctggtggtg aagataccgg tctggttccc ccattacctc ccaccgatat cggtagacat
2221 gtcaaatacc aatggaaccc cgccattaaa tgtattgcga tcatcccaca gttcgagttg
2281 tccaccgccg actccagagg cgttcttcca aaagcctacc caacccagga cttggttttc
2341 aatctacaaa gattggccgt cttgaccaca gctttgacca tggacccacc taatgccgac
2401 ttaatctacc ctgctatgca agatcgtgtc caccaacctt atagaaagac attgatccca
2461 ggtctcacgg aaatcttatc atgtgtcacc ccatccacat accctggcct attgggtatc
2521 tgcttgtcag gtgcaggccc aactatcttg gctttggcca ctgagaattt cgaagaaatc
2581 tctcaagaaa ttatcaacag gttcgccaaa aacggcatca agtgctcctg gaaactactg
2641 gagcctgcct acgatggtgc tagcgtcgaa cagcaatgaa atgtccttta cccctagtat
2701 actgtgttaa atactattgt agaccatata catactgtaa ttgaccgtta acggttatta
2761 tgctgagtct tcttccgtta cccgtctttt ctatctattt cgaaaataaa aaataagtga
2821 aaagaacgaa atttcacaac cattaacaat acagataatg aatcgaagtt gttttcagtc
2881 tcaattcaaa agactcatag ccaaggccag ttgattgatt tagccacaag tatcattcaa
2941 cgtaatatcc acaggtgttt tttttctcac cggaaggcga ataaaataca ggagctagag
3001 cgtgtaagat aatgaacaag gaatctaaag atgatgatat gtccttgggg aagttttcct
3061 tctcccactt cctatattac ttggtgctaa tagtagtaat agtgtacggt ttgtacaagc
3121 ttttcactgg acatggatcc
//