GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS HUMLEU8 2323 bp ss-mRNA PRI 18-MAY-1991
DEFINITION Human mRNA for Leu-8 pan leukocyte antigen
ACCESSION X17519
KEYWORDS antigen; glycoprotein; receptor; transmembrane protein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2323)
AUTHORS Camerini,D., James,S.P., Stamenkovic,I. and Seed,B.
TITLE Leu-8/TQ1 is the human equivalent of the Mel-14 lymph node homing
receptor
JOURNAL Nature 342, 78-82 (1989)
STANDARD full automatic
COMMENT From EMBL entry HSLEU8; dated 28-JAN-1991.
FEATURES Location/Qualifiers
mat_peptide join(:203..1574)
/note="Leu-8 is the human homologue of the mouse Mel-14
receptor"
/product="Leu-8 antigen short form"
mat_peptide join(:203..1074,:1515..1574)
/note="Leu-8 is the human homologue of the mouse Mel-14
receptor"
/product="Leu-8 antigen short form"
mRNA join(:1..1077,:1515..2323)
/note="short form"
/evidence=EXPERIMENTAL
mRNA 1..2323
/note="long form"
/evidence=EXPERIMENTAL
sig_peptide 50..202
CDS 50..1577
/note="Leu-8 antigen"
/codon_start=50
BASE COUNT 652 a 520 c 490 g 661 t
ORIGIN
1 ctccctttgg gcaaggacct gagacccttg tgctaagtca agaggctcaa tgggctgcag
61 aagaactaga gaaggaccaa gcaaagccat gatatttcca tggaaatgtc agagcaccca
121 gagggactta tggaacatct tcaagttgtg ggggtggaca atgctctgtt gtgatttcct
181 ggcacatcat ggaaccgact gctggactta ccattattct gaaaaaccca tgaactggca
241 aagggctaga agattctgcc gagacaatta cacagattta gttgccatac aaaacaaggc
301 ggaaattgag tatctggaga agactctgcc tttcagtcgt tcttactact ggataggaat
361 ccggaagata ggaggaatat ggacgtgggt gggaaccaac aaatctctca ctgaagaagc
421 agagaactgg ggagatggtg agcccaacaa caagaagaac aaggaggact gcgtggagat
481 ctatatcaag agaaacaaag atgcaggcaa atggaacgat gacgcctgcc acaaactaaa
541 ggcagccctc tgttacacag cttcttgcca gccctggtca tgcagtggcc atggagaatg
601 tgtagaaatc atcaataatt acacctgcaa ctgtgatgtg gggtactatg ggccccagtg
661 tcagtttgtg attcagtgtg agcctttgga ggccccagag ctgggtacca tggactgtac
721 tcactctttg ggaaacttca gcttcagctc acagtgtgcc ttcagctgct ctgaaggaac
781 aaacttaact gggattgaag aaaccacctg tggaccattt ggaaactggt catctccaga
841 accaacctgt caagtgattc agtgtgagcc tctatcagca ccagatttgg ggatcatgaa
901 ctgtagccat cccctggcca gcttcagctt tacctctgca tgtaccttca tctgctcaga
961 aggaactgag ttaattggga agaagaaaac catttgtgaa tcatctggaa tctggtcaaa
1021 tcctagtcca atatgtcaaa aattggacaa aagtttctca atgattaagg agggtgatta
1081 taaccccctc ttcattccag tggcagtcat ggttactgca ttctctgggt tggcatttat
1141 catttggctg gcaaggagat taaaaaaagg caagaaatcc aagagaagta tgaatgaccc
1201 atattaaatc gcccttggtg aaagaaaatt cttggaatac taaaaatcat gagatccttt
1261 aaatccttcc atgaaacgtt ttgtgtggtg gcacctccta cgtcaaacat gaagtgtgtt
1321 tccttcagtg catctgggaa gatttctacc tgaccaacag ttccttcagc ttccatttcg
1381 cccctcattt atccctcaac ccccagccca caggtgttta tacagctcag ctttttgtct
1441 tttctgagga gaaacaaata agaccataaa gggaaaggat tcatgtggaa tataaagatg
1501 gctgactttg ctctttcttg actcttgttt tcagtttcaa ttcagtgctg tacttgatga
1561 cagacacttc taaatgaagt gcaaatttga tacatatgtg aatatggact cagttttctt
1621 gcagatcaaa tttcacgtcg tcttctgtat actgtggagg tacactctta tagaaagttc
1681 aaaaagtcta cgctctcctt tctttctaac tccagtgaag taatggggtc ctgctcaagt
1741 tgaaagagtc ctatttgcac tgtagcctcg ccgtctgtga attggaccat cctatttaac
1801 tggcttcagc ctccccacct tcttcagcca cctctctttt tcagttggct gacttccaca
1861 cctagcatct catgagtgcc aagcaaaagg agagaagaga gaaatagcct gcgctgtttt
1921 ttagtttggg ggttttgctg tttcctttta tgagacccat tcctatttct tatagtcaat
1981 gtttctttta tcacgatatt attagtaaga aaacatcact gaaatgctag ctgcaagtga
2041 catctctttg atgtcatatg gaagagttaa aacaggtgga gaaattcctt gattcacaat
2101 gaaatgctct cctttcccct gcccccagac cttttatccg acttacctag attctacata
2161 ttctttaaat ttcatctcag gcctccctca accccaccac ttcttttata actagtcctt
2221 tactaatcca acccatgatg agctcctctt cctggcttct tactgaaagg ttaccctgta
2281 acatgcaatt ttgcatttga ataaagcctg ctttttaagt gtt
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