GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS RATDTACHK 342 bp ss-mRNA ROD 18-MAY-1991
DEFINITION Rat mRNA of delta-preprotachykinin - a splicing variant of
substance P precursor
ACCESSION X56306
KEYWORDS neuropeptide; substance P; tachykinin.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 342)
AUTHORS Harmar,A.J.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Harmar,A.J., Hyde,V. and Chapman,K.
TITLE Identification and cDNA sequence of delta-preprotachykinin, a
fourth splicing variant of the rat substance P precursor
JOURNAL FEBS Lett. 275, 22-24 (1990)
STANDARD full staff_review
COMMENT *source: developmental stage=adult; *source: tissue type=dorsal
root ganglion; library=pGem3; delta-preprotachykinin lacks exon 4
and 6 of preprotachykinin A gene
From EMBL entry RNDTACHK; dated 08-FEB-1991.
FEATURES Location/Qualifiers
mRNA <1..>342
/note="delta-preprotachykinin"
/evidence=EXPERIMENTAL
exon <1..127
/number=2
CDS join(:5..298)
/note="delta-preprotachykinin"
/product="substance P"
/codon_start=5
sig_peptide 5..61
misc_feature 62..172
/note="N-flanking peptide"
exon 128..224
/number=3
mat_peptide 176..208
/product="substance P"
/gene="preprotachykinin A"
misc_feature 218..283
/note="C-flanking peptide"
exon 225..248
/number=5
exon 249..>342
/number=7
BASE COUNT 95 a 83 c 82 g 82 t
ORIGIN
1 caacatgaaa atcctcgtgg cggtggcggt cttttttctc gtttccactc aactgtttgc
61 agaggaaatc ggtgccaacg atgatctaaa ttattggtcc gactggtccg acagtgacca
121 aatcaaggag gcaatgccgg agccctttga gcatcttctt cagagaatcg cccgaagacc
181 caagcctcag cagttctttg gattaatggg caaacgggat gctgggcatg gtcagatctc
241 tcacaaaatg gcttatgaaa gaagcgcaat gcagaactac gaaagaaggc gtaaataaac
301 cctgtaacgc actatctatt catctccatc tgtgtccgcg ag
//