GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS HUMALAS1R 2146 bp ss-mRNA PRI 18-MAY-1991
DEFINITION Human ALAS1 (ALASH) mRNA for delta-aminolevulinate synthase
(housekeeping) (EC 2.3.1.37)
ACCESSION X56351
KEYWORDS 5-aminolevulinic acid synthase; delta-aminolevulinate synthase.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2146)
AUTHORS Bishop,D.F.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Bishop,D.F.
TITLE Two different genes encode delta-aminolevulinate synthase in
humans: nucleotide sequences of cDNAs for the housekeeping and
erythroid genes
JOURNAL Nucleic Acids Res. 18, 7187-7188 (1990)
STANDARD full staff_review
COMMENT *source: tissue=liver; library=pKT218; clone=pAH12; **map:
chomosome=3; map position=3p21 See also <Y00451>.
From EMBL entry HSALAS1R; dated 11-FEB-1991.
FEATURES Location/Qualifiers
mRNA <1..2146
/gene="ALAS1 (ALASH)"
CDS 77..1999
/product="delta- aminolevulinate synthase (housekeeping)"
/gene="ALAS1 (ALASH)"
/codon_start=77
polyA_signal 2124..2129
polyA_site 2146..2146
BASE COUNT 556 a 554 c 534 g 502 t
ORIGIN
1 agtgcccgcc tccttcgccg ccgcctctgc agtcctcagc gcagtctttc cacaggagcc
61 agcatacttc ctgaacatgg agagtgttgt tcgccgctgc ccattcttat cccgagtccc
121 ccaggccttt ctgcagaaag caggcaaatc tctgttgttc tatgcccaaa actgccccaa
181 gatgatggaa gttggggcca agccagcccc tcgggcattg tccactgcag cagtacacta
241 ccaacagatc aaagaaaccc ctccggccag tgagaaagac aaaactgcta aggccaaggt
301 ccaacagact cctgatggat cccagcagag tccagatggc acacagcttc cgtctggaca
361 ccccttgcct gccacaagcc agggcactgc aagcaaatgc cctttcctgg cagcacagat
421 gaatcagaga ggcagcagtg tcttctgcaa agccagtctt gagcttcagg aggatgtgca
481 ggaaatgaat gccgtgagga aagaggttgc tgaaacctca gcaggcccca gtgtggttag
541 tgtgaaaacc gatggagggg atcccagtgg actgctgaag aacttccagg acattatgca
601 aaagcaaaga ccagaaagag tgtctcatct tcttcaagat aacttgccaa aatctgtttc
661 cacttttcag tatgatcgtt tctttgagaa aaaaattgat gagaaaaaga atgaccacac
721 ctatcgagtt tttaaaactg tgaaccggcg agcacacatc ttccccatgg cagatgacta
781 ttcagactcc ctcatcacca aaaagcaagt gtcagtctgg tgcagtaatg actacctagg
841 aatgagtcgc cacccacggg tgtgtggggc agttatggac actttgaaac aacatggtgc
901 tggggcaggt ggtactagaa atatttctgg aactagtaaa ttccatgtgg acttagagcg
961 ggagctggca gacctccatg ggaaagatgc cgcactcttg ttttcctcgt gctttgtggc
1021 caatgactca accctcttca ccctggctaa gatgatgcca ggctgtgaga tttactctga
1081 ttctgggaac catgcctcca tgatccaagg gattcgaaac agccgagtgc caaagtacat
1141 cttccgccac aatgatgtca gccacctcag agaactgctg caaagatctg acccctcagt
1201 ccccaagatt gtggcatttg aaactgtcca ttcaatggat ggggcggtgt gcccactgga
1261 agagctgtgt gatgtggccc atgagtttgg agcaatcacc ttcgtggatg aggtccacgc
1321 agtggggctt tatggggctc gaggcggagg gattggggat cgggatggag tcatgccaaa
1381 aatggacatc atttctggaa cacttggcaa agcctttggt tgtgttggag ggtacatcgc
1441 cagcacgagt tctctgattg acaccgtacg gtcctatgct gctggcttca tcttcaccac
1501 ctctctgcca cccatgctgc tggctggagc cctggagtct gtgcggatcc tgaagagcgc
1561 tgagggacgg gtgcttcgcc gccagcacca gcgcaacgtc aaactcatga gacagatgct
1621 aatggatgcc ggcctccctg ttgtccactg ccccagccac atcatccctg tgcgggttgc
1681 agatgctgct aaaaacacag aagtctgtga tgaactaatg agcagacata acatctacgt
1741 gcaagcaatc aattacccta cggtgccccg gggagaagag ctcctacgga ttgcccccac
1801 ccctcaccac acaccccaga tgatgaacta cttccttgag aatctgctag tcacatggaa
1861 gcaagtgggg ctggaactga agcctcattc ctcagctgag tgcaacttct gcaggaggcc
1921 actgcatttt gaagtgatga gtgaaagaga gaagtcctat ttctcaggct tgagcaagtt
1981 ggtatctgct caggcctgag catgacctca attatttcac ttaaccccag gccattatca
2041 tatccagatg gtcttcagag ttgtctttat atgtgaatta agttatatta aattttaatc
2101 tatagtaaaa acatagtcct ggaaataaat tcttgcttaa atggtg
//