GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS DROSLIT 5401 bp ss-mRNA INV 18-MAY-1991
DEFINITION Drosophila mRNA for slit protein
ACCESSION X53959
KEYWORDS extracellular protein; morphogenesis protein; slit gene.
SOURCE Drosophila melanogaster RNA.
ORGANISM Drosophila melanogaster
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (bases 1 to 5401)
AUTHORS Rothberg,J.M.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Rothberg,J.M., Jacobs,J.R., Goodman,C.S. and Artavanis-Tsakonas,S.
TITLE slit: an extracellular protein necessary for development of midline
glia and commissural axon pathways contains both EGF and LRR
domains
JOURNAL Genes Dev. 4, 2169-2187 (1990)
STANDARD full staff_review
COMMENT From EMBL entry DMSLIT; dated 14-FEB-1991.
FEATURES Location/Qualifiers
mRNA 1..5401
/gene="slit"
/evidence=EXPERIMENTAL
sig_peptide 251..358
/product="slit protein"
CDS 251..4693
/product="slit protein"
/gene="slit"
/codon_start=251
mat_peptide 359..4690
/product="slit protein"
/gene="slit"
misc_feature 4495..4527
/note="alternatively spliced segment"
BASE COUNT 1313 a 1504 c 1528 g 1056 t
ORIGIN
1 gagagaaaag tgcgccgtgg agccgggcgg acattcaccg aacccaaaac gcctcgaact
61 cgatatcgaa tcgaaaggat taatccagtg aaatcagtga agtgaaagtg cctgcgaacg
121 catcatcaat cctttatcct ttctccctca aatatttacc cagtggtgat tgctgttgac
181 aaagtggatt ggcatatacg ggggccactt tcaattaggc acgttgccgc tgcttcataa
241 atgtgccaca atggccgcgc cgtccaggac gacgttgatg ccaccaccat tccggctcca
301 gctgcggcta ctgatactac ccatcctgct actcctgcgc catgatgcgg tccacgcgga
361 accgtattcc ggcggattcg gcagctcagc tgtatccagc ggtggactgg ggtcagtggg
421 cattcacata cccggcggcg gagtgggcgt catcacggag gcccgctgcc cgagggtctg
481 ctcctgcacc ggattaaatg tggattgctc gcatcgagga ctcacctccg ttcccaggaa
541 aatctcagcg gacgtggagc gactcgagct gcagggaaac aatttgaccg tgatatacga
601 gacggatttc cagcggctga ccaagctgcg aatgctccaa ctaactgaca atcagatcca
661 cacgatcgag aggaactcct tccaagattt ggtctcactc gagcgactgg acatctccaa
721 caatgtcatc acgaccgtgg gtagacgcgt cttcaaggga gcccaatcgt tgcggagtct
781 tcagctggac aataaccaaa tcacctgcct ggatgagcac gcctttaagg gattggtgga
841 gctggagata ctcacgctga acaacaacaa cctgacttcc ctgccgcaca acatcttcgg
901 cggactggga cgtttgcggg cactccggct gtcggacaat ccgttcgcct gcgactgcca
961 tctgtcctgg ctgtcgcgat tccttcgcag tgccacccgc ctggcgccct acacccgctg
1021 ccagtcgcca tcgcagctga agggccaaaa cgtggcggac ctgcacgacc aggagttcaa
1081 atgctcgggt ctgacggagc acgcaccgat ggaatgcggg gcggagaaca gctgtccgca
1141 cccatgtcgc tgtgcggacg ggatcgtcga ttgccgtgag aagagtctga ccagcgtgcc
1201 cgtcaccttg cccgacgaca ccaccgacgt tcgcctcgag caaaatttca ttacggaact
1261 gccgccgaaa tcgttctcca gctttcgacg actgcgacgc atcgacctgt ccaacaacaa
1321 catatcccgg attgcccacg atgcactaag cggcctaaag cagttaacca ctctcgtgct
1381 gtacggcaat aaaataaagg atttaccctc gggcgtgttc aaaggactcg gctcgctcag
1441 gctgctgctg ctgaacgcca acgagatctc gtgcatacgc aaggatgcct ttcgcgacct
1501 gcacagtttg agcctgctct ccctgtacga caacaacatc cagtcgctgg ctaatggcac
1561 attcgacgcc atgaagagca tgaaaacggt acatctggcc aagaatcctt tcatctgcga
1621 ctgcaatctg cgctggctgg ccgactattt gcacaaaaat cccatagaga cgagtggagc
1681 ccgctgcgag tcaccgaagc ggatgcatcg tcgtcggatt gaatcgctgc gcgaggagaa
1741 attcaaatgc tcctggggtg aattgcggat gaagctgtcc ggcgagtgcc gcatggactc
1801 cgactgtccg gccatgtgcc actgcgaggg caccaccgtg gattgcacgg gccggcggct
1861 gaaggagatt ccgcgcgaca ttcccctgca cacaactgag cttttgctca acgacaacga
1921 actgggacgc atcagttccg atggcctctt tggtcgcctg ccgcacttgg tgaagctgga
1981 attgaagcgc aaccagctga ccggcatcga gcccaacgcc ttcgagggag catcccacat
2041 ccaggagttg cagctgggcg agaacaagat caaggagata tcgaacaaga tgttcctggg
2101 actgcaccaa ctaaaaacgc tcaatctgta cgacaatcaa atctcatgcg ttatgcccgg
2161 ttcctttgag catctcaact ctctgacgtc gctgaacctc gcatcgaatc cattcaattg
2221 caattgtcat ttggcctggt tcgcggaatg cgtgcgcaaa aaatcactga acggcggagc
2281 ggcacgttgt ggagccccgt cgaaggtacg tgacgtgcag atcaaggact tgccccactc
2341 ggaattcaag tgtagcagcg agaacagcga gggctgcctg ggcgatggct actgtccgcc
2401 atcctgcacc tgcaccggca ccgtggtcgc ctgttcgcgt aaccagctga aggagatacc
2461 gcgaggcatt cccgccgaaa catcggagct gtatctggag tccaatgaga tcgagcagat
2521 tcactacgaa cgcatacgcc atttgcgctc ccttacccga ctcgatctca gcaacaacca
2581 gatcaccatt ctttccaact acacctttgc caatctgacc aagctgtcca cgctcatcat
2641 ctcatacaac aagctgcagt gtctgcagcg gcatgcgttg tctggcctga ataacctgcg
2701 cgtcgtttcg ctgcacggta accgcatctc gatgctgccg gaaggctcct tcgaggacct
2761 caagtcgttg acccacatcg cactaggcag caatcccttg tactgcgact gcggtctaaa
2821 gtggttctcc gattggatca agctggacta cgtggaaccg ggaattgcac gttgcgccga
2881 accggaacag atgaaggata agctgatcct gtccacaccc tcgtcgagct tcgtttgccg
2941 cggccgcgtg cgcaatgata ttctggccaa gtgcaacgcc tgtttcgagc agccatgcca
3001 gaatcaggcg cagtgtgtgg cccttccgca gcgagagtac cagtgcctct gccagccggg
3061 ctatcatggg aaacactgtg agtttatgat cgatgcttgc tacggaaatc cgtgccgcaa
3121 caatgccacc tgcacggtgc tggaggaggg tcgattcagc tgtcagtgcg ctccgggata
3181 cacaggtgcc cgctgcgaga cgaatatcga cgattgcctg ggcgagatca agtgccagaa
3241 caatgccacc tgcatcgacg gagtggagtc gtacaaatgt gagtgccagc cgggattcag
3301 tggcgagttc tgcgacacca aaatccagtt ctgcagtccg gagttcaatc cctgcgcgaa
3361 tggagccaag tgcatggacc actttaccca ctacagctgc gattgtcagg caggtttcca
3421 tggcaccaac tgcacggaca atattgacga ctgccagaac cacatgtgcc agaacggtgg
3481 aacgtgcgtg gacggcatca acgactacca atgccgctgt ccagacgact atacgggcaa
3541 gtactgtgaa ggccacaaca tgatctcgat gatgtatcca cagacgtcgc cttgtcaaaa
3601 ccacgagtgc aagcacggtg tctgcttcca accgaacgct cagggcagcg actacctatg
3661 caggtgtcat ccgggttaca ctggaaagtg gtgcgagtac ctcaccagca ttagcttcgt
3721 ccacaacaac tcgtttgtgg aactggagcc actgcgaaca cgtccggagg cgaacgtgac
3781 gatagtcttc agcagcgcgg agcagaatgg aattctcatg tacgacggcc aggatgcaca
3841 tctcgcagtg gagctgttta atgggcgtat tcgggttagc tacgatgtgg gtaatcaccc
3901 tgtgtccacg atgtacagct ttgaaatggt ggccgatgga aagtaccatg ccgtggagct
3961 tctggccatc aagaagaatt tcacgctgcg cgtggatcgc ggattggccc gttccatcat
4021 caacgagggc tccaacgact acctgaaact tacgactccc atgttcctgg gcggcctacc
4081 agtggatcct gcacagcagg catacaagaa ctggcaaata cgcaacctta ccagctttaa
4141 gggctgcatg aaggaggtgt ggatcaatca taagctggtc gactttggca atgcccagcg
4201 ccagcaaaag atcacaccag gatgtgccct gctcgaagga gagcagcaag aggaggaaga
4261 cgacgagcag gatttcatgg acgagacacc gcacatcaaa gaggagccgg tggatccttg
4321 cctggagaac aaatgccgtc ggggcagtcg ctgtgtgccg aattccaatg ccagggacgg
4381 ctaccagtgc aagtgcaagc acggccagcg cggccgctac tgcgatcaag gtgagggcag
4441 cactgagccc ccaacagtca ccgcggcgtc cacctgtcgc aaggagcagg tgcgcgagta
4501 ctacacggag aacgactgtc gctcgaggca gccgttgaag tacgccaagt gcgtgggcgg
4561 ctgcggcaac cagtgctgcg cggccaaaat tgtgagacgg cgcaaggtgc gcatggtgtg
4621 cagcaacaac cgcaagtaca tcaagaactt ggacatcgtg cgcaagtgcg gatgcaccaa
4681 gaaatgctac tgactgaaag atgcgactac ccaattgctc gaacggagca atagcagctt
4741 agatgttagt ttaggaacag gtttaaatct aacttatagt agtagtaata gtaacgatag
4801 tcttagccat agcactaggg atagcacgga tgttaggggg acgaaggatg aagtggagga
4861 gagtgctgac gcgggggaga caacggagga ggtgagggac gagagtgatg attaccccac
4921 ggacggcatg cagtccgatc tctacgacga caccatcgat gacgacgatg acgatggtct
4981 cgatgatgat tatgcagacg aggaggatgg ggaggaggat ccagagcagc ttcccgatcc
5041 caagggtctg gtaagtgtgc cagatgaaga ggaagacatg ggttacgacg aggatgacga
5101 acgtatcgcc atggagcggc caagaacggt tagacccagg cccgacgagg agcatttcct
5161 taacgaagag ggcagtggtt tcggtggctt tcgatcgcga ttccggccga gcaatagctt
5221 ccgcgagact cagctggaga atatccgcaa gaagctgctc acagaagcac aggcggctcc
5281 ggaaacggct gttgcggtgg ccgtgccgag cactgcgata gatctgcgcg agagcagcgg
5341 ccactttgcc aacgatgacg aggatggcga ggacggcgat gacggcgtcg atgacgaatt
5401 c
//