GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS MUSIGMUD3 6800 bp ds-DNA ROD 18-MAY-1991
DEFINITION Mouse germline Ig H-chain C(mu4) to C(delta3) gene region
ACCESSION X00142
KEYWORDS Z DNA; constant region; delta-immunoglobulin; germ line;
immunoglobulin; immunoglobulin heavy chain; inverted repeat;
mu-immunoglobulin; pseudogene; unidentified reading frame.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1709 to 2428)
AUTHORS Early,P., Rogers,J., Davis,M., Calame,K., Bond,M., Wall,R. and
Hood,L.
TITLE Two mRNAs can be produced from a single immunoglobulin mu gene by
alternative RNA processing pathways
JOURNAL Cell 20, 313-319 (1980)
STANDARD full automatic
REFERENCE 2 (bases 4631 to 4934; 5311 to 5415; 6415 to 6735; 6736 to 6800)
AUTHORS Tucker,P.W., Liu,C.-P., Mushinski,J.F. and Blattner,F.R.
TITLE Mouse immunoglobulin D: Messenger RNA and genomic DNA sequences
JOURNAL Science 209, 1353-1360 (1980)
STANDARD full automatic
REFERENCE 3 (bases 1 to 6800)
AUTHORS Richards,J.E., Gilliam,A.C., Shen,A., Tucker,P.W. and Blattner,F.R.
TITLE Unusual sequences in the murine immunoglobulin m-delta heavy-chain
region
JOURNAL Nature 306, 483-487 (1983)
STANDARD full automatic
COMMENT for Cmu(s) gene see also <mmigm2>
From EMBL entry MMIGMUD3; dated 20-FEB-1991.
FEATURES Location/Qualifiers
CDS 2..59
/note="secreted carboxyl terminal part of Cmu(s) (2 is 3rd
base in codon)"
/codon_start=2
misc_feature 108..743
/note="pot. z-DNA region"
polyA_site 163..168
/note="polyadenylation signal for Cmu(s)"
polyA_site 676..681
/note="pot. polyadenylation signal"
misc_feature 1097..1161
/note="(CA)33 repeat"
CDS 1863..1978
/note="membrane carboxyl terminal of Cmu(m) (1863 is 3rd
base in codon)"
/codon_start=1863
intron 1979..2096
/note="intron"
CDS 2097..2102
/note="membrane carboxyl terminal part of Cmu(m)"
/codon_start=2097
polyA_site 2348..2353
/note="polyadenylation signal for Cmu(m)"
misc_feature 2556..2627
/note="(GGGAGA)12-repeat"
misc_feature 2636..2691
/note="(GA)28-repeat"
polyA_site 3367..3372
/note="pot. plyadenylation signal for Cmu(m)"
promoter 3367..3372
/note="pot. TATA-like motive for ORF 146"
CDS 3461..3898
/note="open reading frame ORF 146"
/codon_start=3461
misc_feature 3479..3481
/note="pot. start codon of ORF 146"
repeat_unit 3519..3680
/note="unique sequence inverted repeat 1"
misc_feature 3743..3823
/note="pot. stretch of 27 hydrophobic amino acids,
membrane binding segment"
repeat_unit 3936..4098
/note="unique sequence inverted repeat 1'"
CDS 4653..4934
/note="C delta 1 (4653 is 2nd base in codon) (4934 is 1st
base in codon)"
/codon_start=4653
polyA_site 4895..4900
/note="pot. polyadenylation signal for ORF 146"
CDS 5311..5415
/note="C delta hinge (5311 is 2nd base in codon) (5415 is
1st base in codon)"
/codon_start=5311
misc_feature 5851..5910
/note="(CT)30-repeat"
misc_feature 5911..5970
/note="(CA)30-repeat"
misc_feature 5989..6325
/note="pot. pseudogene for C gamma 3"
CDS 6415..6735
/note="C delta 3 (6415 is 2nd base in codon) (6735 is 1st
base in codon)"
/codon_start=6415
BASE COUNT 1953 a 1758 c 1500 g 1589 t
ORIGIN
1 gtaaacccac actgtacaat gtctccctga tcatgtctga cacaggcggc acctgctatt
61 gaccatgcta gcgctcaacc aggcaggcct tgggtgtcca gttgctctgt gtatgcaaac
121 taaccatgtc agagtgagat gttgcatttt ataaaaatta gaaataaaaa aaatccattc
181 aaacgtcact ggttttgatt atacaatgct catgcctgct gagacagttg tgttttgctt
241 gctctgcaca caccctgcat acttgcctcc accctagccc ttcctctacc ttgccagttt
301 cctccttgtg tgtgaactca gtcaggctta caacagacag agtatgaaca tgcgattcct
361 ccagctactt cttgatatat ggctgaaagc ttgcctaacc tggtgcaggc agcattcagg
421 cacatatata gacacacatg catttataca tagatatata ggtacacatg tgtagacaca
481 tacatgaatg tgtattcatg gacacacaga caaaggtaca catatataca catgagttca
541 tgcgcacaca catgcatgga cacttacaaa cgccttcaga gacaaatagg catagacaca
601 caaccactca cagaaacaga taccaatatg catggtcctg tgtacacaga aacagactat
661 aggcaaatat acacaaataa actatataga tacaaagata tgcatataca cacatgtaca
721 gaaacatctt cacatgtgta cactaacatg tggacaggta tagcacacag atacacctgg
781 actctgacca ggccgtaatc tccaaggctc acggctcaga gagcctacac taggctgggt
841 cactgatact cctcaggagc ccactctatg attgggagag ataaccccag gtacaaagta
901 tgcctatctg tctcaacacc atggggcaga agatactcca ctaaccaccc atgacagaaa
961 gttagccttg gctgtgtctc cattaataga acacctcaga agaccaatgt gaaattgcct
1021 aacccactca cacccaccct gatctccagt tcaaaatgca gaaaacacaa tgcagctgtc
1081 caaaagatgc cccaaccaca cacacacaca cacacacaca cacacacaca cacacacaca
1141 cacacataca cacacacaca ccatcaagga gcctctgtaa ggagtcacca cccaataaca
1201 ctgcctcttt gggctcatat cctagacatt cttcatattc atatccattt ggggcctagg
1261 ctttagatat ccccaagggc tcatctttac agggatcaga gatcccaata aatgccctgg
1321 tcccacagcc tccctcaggt atctgtctgt ttatctcttg gtaccaagac ccaacattgc
1381 tggcaggggt aggacaagca acgcacggga actctgatca aagaaagtca tgagatgtcc
1441 gagtccttca ggaagtaagg agggacaacc tctggtatcc ctgttcttat tgctaaagcc
1501 caagagacag ggagacctgc tctaaattct cagtctaaac agcaccgatg gcaccacctg
1561 ctcagagaaa gtccagagca caccaatatc attttgccac agttcctgag tctgccttta
1621 cccaggtcca tacattgcat ctgtcttgct tgctctgctg cccagggctc ctggaacaaa
1681 ggctccaaat tagtgtgtcc tacagcttgg cctgttctgt gcctccgtct agcttgagct
1741 attaggggac cagtcaatac tcgctaagat tctccagaac catcagggca ccccaaccct
1801 tatgcaaatg ctcagtcacc ccaagacttg gcttgaccct ccctctctgt gtcccttcat
1861 agagggggag gtgaatgctg aggaggaagg ctttgagaac ctgtggacca ctgcctccac
1921 cttcatcgtc ctcttcctcc tgagcctctt ctacagcacc accgtcaccc tgttcaaggt
1981 agtatggttg tggggctgag gacacagggc tgggacaggg agtcaccagt cctcactgcc
2041 tctacctcta ctccctacaa gtggacagca attcacactg tctctgtcac ctgcaggtga
2101 aatgactctc agcatggaag gacagcagag accaagagat cctcccacag ggacactacc
2161 tctgggcctg ggatacctga ctgtatgact agtaaactta ttcttacgtc tttcctgtgt
2221 tgccctccag cttttatctc tgagatggtc ttctttctag actgaccaaa gactttttgt
2281 caacttgtac aatctgaagc aatgtctggc ccacagacag ctgagctgta aacaaatgtc
2341 acatggaaat aaatacttta tcttgtgaac tcactttatt gtgaaggaat ttgttttgtt
2401 tttcaaacct ttcctgcggt gttgacagcc caaggattat ctgaatagag cctaggaact
2461 ggaaatggaa cagtgcagtc tgatggtact taagggagaa agagggaaag gaggtgtgga
2521 agaagaaaaa agagaagcaa gggggggggg agaaagggag agggagaggg agagggagag
2581 ggagagggag agggagaggg agagggagag ggagagggag agggagaggg agggggagag
2641 agagagagag agagagagag agagagagag agagagagag agagagagag agcatgcact
2701 ctaacagcaa agtacaacac aggcagccaa tggataacac tctggttatc taccctgatg
2761 gaagaaggga agtagggcag agaaaattcc aggcctaatc tcccaaaagc aacagaacct
2821 ggaaactagc ctctagcctt aggtctctgc tctgtcccca gcccaccatc ttgggctggt
2881 gttgcttcaa agctagtaat ttaggtctta tcccaaagct ttgtggtatg tgggtgtgcc
2941 tttggggagt tggctgagat tttgaagatg tttgtacctc tcccacaaca tgacaagccc
3001 taggggttag tcaataactc aaattctctg tctatgacaa ctgctgtatg actatatgaa
3061 gaaatgggat aaagatgcta tagtcactcg aggacagata aaggcctgct cacagagcaa
3121 gaatggaaag gagaggaagg caggtcatgg acttcagttc agagaaggaa gcacagcaaa
3181 tacaaggtga gggccatgct agttactccc ttgttcatca tgtggacagc tagagaagcc
3241 cactgacatg ggaagtctgg gctaactgac tacattgaga ggaggacctg gaagcagggc
3301 atgagagaga acatcagacc atgggaggga tctgtgtaga tgccagggtc ctaaagagag
3361 tctttaaata aatgtgtggg gtagcacctt ggtgatggtc cctttctgag ttgggattct
3421 agtgggtagc tgcaggatac agagagaaga aatcatctaa tgggaaacca ctgtagagat
3481 gataggactc gtcaccaaat tccagatata ttgtagtcat tcaccatggt atggtacttc
3541 tcataccagc atctattttt gttaccctgg gatgctgggg caaagtgcca cacatggcag
3601 tttgagcagc agaactctgt tctttcccag ttctagaggc cagaagtgtg ggccacagca
3661 agctctgctc tgtccccagc ccaccatctt gggctggtgt tgcttcaagc tagtaatttg
3721 ggtcttatcc caaagctctg aggccatagc agttggtcaa tccttgtctc ctggcaccaa
3781 catcccagtc actgtatgtc ctttgtacct aatgccatgt ttcaagaacc cagtcctact
3841 gggtttgatg ccaaccctga ttcagcacaa gttcatctcc actaggttcc acccgccatg
3901 acctcagagc tagaagtctg tgacagattc tccctgctgc acagaggata ccagcctgat
3961 gtagcccaga ctcctagcct ctagaacagg gaaagaacag aattctgttg ctcaaactgc
4021 cataggtggc actttgcccc agcagcccaa agaaactaac atagatgctg gtatatgaca
4081 tagggtatag aggtgactct ggaattggat gatgaaccct gacatcccta catgaatgtt
4141 ggtttcagca agcaagtctg gcgggggggg ggtgtcacag gtctacactt atatcttttg
4201 cttgtctctg ggatactgta gaatgggaca ttgaaaatat ttgatatccc agaacctgag
4261 aaggaagagt agtgcagaca gaaccgaacc atgacttggg gaaaggagtc aggctgctct
4321 gctcagatga tacaagctgc tcagggggct atgagaatac agaaggctgg ctgttcctgt
4381 tagagtcaca aaagaattat attcatggga ggggagaatc attggtgctt agaagagtag
4441 gaggtagatc tcttcctaag agggggtttc agacaaagat gatggtgaca gagagacagg
4501 ctcctgagac tggccatagg gcttaaggcc cttctcccct gtcttcttgg gactgagtca
4561 tttttatgac tctggcaaga agagtgatac tgtccagacc tcacctttgt ccccagttcc
4621 atgtcctcag aacttcacta tctgtcttgc aggtgataaa aaggaacctg acatgttcct
4681 cctctcagag tgcaaagccc cagaggaaaa tgaaaagata aacctgggct gtttagtaat
4741 tggaagtcag ccactgaaaa tcagctggga gccaaagaag tcaagtatag ttgaacatgt
4801 cttcccctct gaaatgagaa atggcaatta tacaatggtc ctccaggtca ctgtgctggc
4861 ctcagaactg aacctcaacc acacttgcac cataaataaa cccaaaagga aagaaaaacc
4921 tttcaagttt cctggtgagt atccctgacc atgcagaagg gccttgtggg acttctcata
4981 cccacactca gctaatcccc aaagattgac tgaagcaaga catcccccca actttgatcc
5041 ctccccttcc ttgctcttcc cccattcatt ccctcccttt tctcagctgc ttcatcaaca
5101 caacacttga catccacacc tcagaaaccc tagtactaac agtgcaagga tgcagctggg
5161 tgagcaaagg cactagctat gtatggtccc ttccatagca gtaccattcc atcctgtggc
5221 cctcctctct cactgcgttc catcaccctg ggctccacgg aatactctga tctctcacca
5281 tcgctttttg tccatcttct ttaactccag agtcatggga ttcccagtcc tctaagagag
5341 tcactccaac tctccaagca aagaatcact ccacagaagc caccaaagct attaccacca
5401 aaaaggacat agaaggtaga gtccggatgt gccaacacaa ctcttcaacc ttacacctct
5461 tgctcctgaa accctccatg actctttctc tgagctgtca atgtacatcc taggtagaac
5521 aggttactaa aatgacttct gtactggcaa gccaggcctt atatcaaggc acaatcaaat
5581 accaccacct aaccctgaga agccatcatc ccttcttgag ctaatgctaa acagaggccg
5641 gacaaggacc tacttagccc acaggaccgt gagctctgcg catctgaccc gaactgtgag
5701 gtcctcatgg actctgtagg catgtgacca gacaaacaac aagacatttc tgaggcgcat
5761 aagaatctcg ttaaagggct agagaccatt acacctagat tggaagactt attgtacccc
5821 acatgttgtc ttcacctctt cctaactatt ctctctctct ctctctctct ctctctctct
5881 ctctctctct ctctctctct ctctctctct cacacacaca cacacacaca cacacacaca
5941 cacacacaca cacacacaca cacacacaca gagagagagc ctaactagga ttggaagata
6001 ggaagcctag gattagcctg ccttcagaat acagaatagg gacatagaga atagctgggg
6061 caccaaagaa aacctacaaa aagccacaca gaagcaagca tgggtctgtt caggcagcac
6121 tgggcatctc taggagctag acagtgacca ggagaagcaa tgtctccaac ataggccttt
6181 ccttaccagg cccttgggcc ccaaggcaag ggcagcctat tttctagatg aaacctatcc
6241 caccccaccc caaggctgtc caatgcccca cctaaccata tgtccttccc ccaacattgt
6301 tcaagccata actgtaatca gataagaaag gggatttcct ctgtcctctc acacatttct
6361 agatacctcc atcccaaaca tgacaagatt agcctcttgc cacttcccaa gcaggggcca
6421 tggcacccag caacctcact gtgaacatcc tgaccacatc cacccatcct gagatgtcat
6481 cttggctcct gtgtgaagta tctggcttct tcccggaaaa tatccacctc atgtggctgg
6541 gtgtccacag taaaatgaag tctacaaact ttgtcactgc aaaccccacc gcccagcctg
6601 ggggcacatt ccagacctgg agtgtcctga gactaccagt cgctctgagc tcatcacttg
6661 acacttacac atgtgtggtg gaacatgagg cctcaaagac aaagcttaat gccagcaaga
6721 gcctagcaat tagtggtaag tcacaactgg gtaagagtgt caatcaagga cagcacttgg
6781 tacctatgat agacaaatac
//