GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS MUSH2D4Q5 1108 bp ds-DNA ROD 18-MAY-1991 DEFINITION Murine MHC class I mutant H-2D4(q) gene, 5' region. ACCESSION X52914 X52595 KEYWORDS Major histocompatibility complex; major histocompatibility complex class I; transplantation antigen. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 1108) AUTHORS Lee,D.R. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 1 to 1108) AUTHORS Rubocki,R.J., Lee,D.R., Lie,W.R., Myers,N.B. and Hansen,T.H. TITLE Molecular evidence that the H-2D and H-2L genes arose by duplication. JOURNAL J. Exp. Med. 171, 2043-2061 (1990) STANDARD full automatic COMMENT From EMBL entry MMH2D4Q5; dated 21-FEB-1991. FEATURES Location/Qualifiers mRNA join(:<95..158,:374..643,:788..>972) /note="gene probably non-functional; deletions in exon 3 produce a premature stop codon" /gene="H-2D4(q)" exon <95..158 /gene="H-2D4(q)" CDS join(:95..158,:374..643,:788..882) /note="gene probably non-functional; deletions in exon 3 produce a premature stop codon" /gene="H-2D4(q)" /codon_start=95 5'UTR 1..94 CAAT_signal 14..18 /note="atypical for most class 1 genes" TATA_signal 41..45 sig_peptide 95..158 /note="for H-2D4(q) polypeptide" intron 159..373 /number=1 exon 374..643 /gene="H-2D4(q)" intron 644..787 /number=2 exon 788..1054 /number=3 /gene="H-2D4(q)" misc_feature (827.828)..(827.828) /note="position of 13 bp deletion that results in a premature termination of the D4 gene product." misc_feature (966.973)..(966.973) /note="position of 4 bp insertion that creates a potential poly(A) signal" polyA_site 967..972 intron 1055..>1108 /number=3 BASE COUNT 210 a 342 c 362 g 194 t ORIGIN 1 ggatcctggg gaaccaagga gctactccgc aggcgctggt tataaagtcc atgcaggcca 61 agggtctcag atgtcctgta ttccagatgg ggcaatggcg ctgcaaaggc tgctcctgct 121 gctggcagcc gccctgaccc tgaccaagac ccgagcaggt gagtgcgggg gtccgcaggg 181 aaacagacct ttccaaacag tctgcgggga ggggcgggca cagcaccggg gaagctgcgt 241 gcccgcgtcg cccaccgtac tctcagtctc ttctccacct gcgtcccgag ccccacgccc 301 tgttccctcc ccgtccgcgc acccgcccag ggtcctggga ggaggtcagg ttctcacagc 361 gcgccgcccc caggctcaca ctcgctgcgg tatttccaca ccgccatgtc ccggccgggc 421 cttcaggagc cctggttcat ctctgtcggc tacgtggacg acacgcagtt cgtgcgcttc 481 gacagcgacg cggagaatcc gagatacgag cctcgtgtgt cgtggatgga gcaagagggg 541 ccggagtatt gggaggagca gatacagatc gccaagagca atgagcagag attccgaggg 601 agcctgagga acgcgctgcg ctactacaac cagagcgagg gcggtgagtc atgactcctc 661 atcttcccgg caccgggttg gagacgtccc ggatccgaag tttgggagca gaaccgccca 721 gagacttgtt gccttttcag tttggaggag tccgcgggag ggcggggctg accgcggggt 781 cccgcaggct ctcacacgtt ccagtggatg tctggctgtg acctcggctc ctccgcgggt 841 acatgcagtt cgcttatgaa ggctgcgatt acatcgccct gaacgaagac ctgaacacgt 901 gaactgtggc ggacatggcg gcgcagatca cccgacacaa ctgccaggag gctggtgctg 961 cagagaaata aatacagggc ctacctggag ggcacctgct tggagaggct cctcagatac 1021 ctgcagctcc ggaaggagat cgtgctgcgc acaggtgcag gggccgcggg cagctcctcc 1081 ctctgccctc gggctggggc tcagtctg //