GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS MUSH2D4Q5 1108 bp ds-DNA ROD 18-MAY-1991
DEFINITION Murine MHC class I mutant H-2D4(q) gene, 5' region.
ACCESSION X52914 X52595
KEYWORDS Major histocompatibility complex;
major histocompatibility complex class I; transplantation antigen.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1108)
AUTHORS Lee,D.R.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1108)
AUTHORS Rubocki,R.J., Lee,D.R., Lie,W.R., Myers,N.B. and Hansen,T.H.
TITLE Molecular evidence that the H-2D and H-2L genes arose by
duplication.
JOURNAL J. Exp. Med. 171, 2043-2061 (1990)
STANDARD full automatic
COMMENT From EMBL entry MMH2D4Q5; dated 21-FEB-1991.
FEATURES Location/Qualifiers
mRNA join(:<95..158,:374..643,:788..>972)
/note="gene probably non-functional; deletions in exon 3
produce a premature stop codon"
/gene="H-2D4(q)"
exon <95..158
/gene="H-2D4(q)"
CDS join(:95..158,:374..643,:788..882)
/note="gene probably non-functional; deletions in exon 3
produce a premature stop codon"
/gene="H-2D4(q)"
/codon_start=95
5'UTR 1..94
CAAT_signal 14..18
/note="atypical for most class 1 genes"
TATA_signal 41..45
sig_peptide 95..158
/note="for H-2D4(q) polypeptide"
intron 159..373
/number=1
exon 374..643
/gene="H-2D4(q)"
intron 644..787
/number=2
exon 788..1054
/number=3
/gene="H-2D4(q)"
misc_feature (827.828)..(827.828)
/note="position of 13 bp deletion that results in a
premature termination of the D4 gene product."
misc_feature (966.973)..(966.973)
/note="position of 4 bp insertion that creates a potential
poly(A) signal"
polyA_site 967..972
intron 1055..>1108
/number=3
BASE COUNT 210 a 342 c 362 g 194 t
ORIGIN
1 ggatcctggg gaaccaagga gctactccgc aggcgctggt tataaagtcc atgcaggcca
61 agggtctcag atgtcctgta ttccagatgg ggcaatggcg ctgcaaaggc tgctcctgct
121 gctggcagcc gccctgaccc tgaccaagac ccgagcaggt gagtgcgggg gtccgcaggg
181 aaacagacct ttccaaacag tctgcgggga ggggcgggca cagcaccggg gaagctgcgt
241 gcccgcgtcg cccaccgtac tctcagtctc ttctccacct gcgtcccgag ccccacgccc
301 tgttccctcc ccgtccgcgc acccgcccag ggtcctggga ggaggtcagg ttctcacagc
361 gcgccgcccc caggctcaca ctcgctgcgg tatttccaca ccgccatgtc ccggccgggc
421 cttcaggagc cctggttcat ctctgtcggc tacgtggacg acacgcagtt cgtgcgcttc
481 gacagcgacg cggagaatcc gagatacgag cctcgtgtgt cgtggatgga gcaagagggg
541 ccggagtatt gggaggagca gatacagatc gccaagagca atgagcagag attccgaggg
601 agcctgagga acgcgctgcg ctactacaac cagagcgagg gcggtgagtc atgactcctc
661 atcttcccgg caccgggttg gagacgtccc ggatccgaag tttgggagca gaaccgccca
721 gagacttgtt gccttttcag tttggaggag tccgcgggag ggcggggctg accgcggggt
781 cccgcaggct ctcacacgtt ccagtggatg tctggctgtg acctcggctc ctccgcgggt
841 acatgcagtt cgcttatgaa ggctgcgatt acatcgccct gaacgaagac ctgaacacgt
901 gaactgtggc ggacatggcg gcgcagatca cccgacacaa ctgccaggag gctggtgctg
961 cagagaaata aatacagggc ctacctggag ggcacctgct tggagaggct cctcagatac
1021 ctgcagctcc ggaaggagat cgtgctgcgc acaggtgcag gggccgcggg cagctcctcc
1081 ctctgccctc gggctggggc tcagtctg
//