GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS RATIID2G 7701 bp ds-DNA ROD 18-MAY-1991
DEFINITION Rat P450 IID2 gene.
ACCESSION X52027 X52455
KEYWORDS Cytochrome P450; cytochrome; cytochrome P450 IID2.
SOURCE Rattus sp. DNA.
ORGANISM Rattus sp.
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 7701)
AUTHORS Matsunaga,E., Umeno,M. and Gonzalez,F.J.
TITLE The rat P450 IID subfamily: complete sequences of four closely
linked genes and evidence that gene conversions maintained sequence
homogeneity at the heme-binding region of the cytochrome P450
active site.
JOURNAL J. Mol. Evol. 30, 155-169 (1990)
STANDARD full automatic
COMMENT From EMBL entry RSIID2G; dated 21-FEB-1991.
FEATURES Location/Qualifiers
mat_peptide join(:592..780,:1394..1565,:1799..1951,:2025..2185,
:2861..3037,:3216..3357,:3545..3732,:4063..4204,
:4305..4480)
/product="cytochrome P450 IID protein"
/gene="P450 IID2"
mRNA join(:<592..780,:1394..1565,:1799..1951,:2025..2185,
:2861..3037,:3216..3357,:3545..3732,:4063..4204,
:4305..>4483)
/gene="P450 IID2"
/evidence=EXPERIMENTAL
exon <592..780
CDS join(:592..780,:1394..1565,:1799..1951,:2025..2185,
:2861..3037,:3216..3357,:3545..3732,:4063..4204,
:4305..4483)
/product="cytochrome P450 IID protein"
/gene="P450 IID2"
/codon_start=592
TATA_signal 440..443
/note="putative and atypical"
prim_transcript 519..>4634
/gene="P450 IID2"
/evidence=EXPERIMENTAL
intron 781..1393
/number=1
exon 1394..1565
intron 1566..1798
/number=2
/cons_splice=(5'site:no,3'site:yes)
/note="gc instead of gt"
exon 1799..1951
intron 1952..2024
/number=3
exon 2025..2185
intron 2186..2860
/number=4
exon 2861..3037
intron 3038..3215
/number=5
exon 3216..3357
intron 3358..3544
/number=6
exon 3545..3732
intron 3733..4062
/number=7
exon 4063..4204
intron 4205..4304
/number=8
exon 4305..>4483
polyA_signal 4533..4538
polyA_site 4634..4634
BASE COUNT 2039 a 1783 c 2019 g 1859 t 1 others
ORIGIN
1 aagcttcaca ggctggagtt accttcctca cactgcctct ccctcaccct catcagctac
61 ccacacaagc cacttcagtg gcccttgctg catactgata gtggccatgg tgtcagtcag
121 accccatgtc tgactagcca agtgtttctg gaagcctcca aaagttcctc ttccaatctg
181 agacgatgcc ctcaggcccc gtggatctct gcccataagg caaatcagca gcttgcacac
241 tgaggaaggg ttcatgttat gtgcttgtct tgctcaaaat gtccagccca acataaccac
301 tatgctgctt tctgtggaga tttcaatgcc actcccatgg acaagcacca ccggagagaa
361 gaaagggcaa gaacctctga tgtttatttt ccctggactt ttctgacacc ccttccccca
421 tacaggctct gtttgaacat taacacagct acttggctca atttagagaa caaagtgcag
481 ctttaccccc ttttaaggga ccaggttccc agtctgttgt aagaggatct ttcctgattc
541 taagtgtctg gacaagtatt ccttcaaaag cctgcaagcc gtggggcagc catggggctg
601 ctgattggag atgacctctg ggctgtggtc atattcacag ccatcttctt gcttctggtg
661 gacctggtgc accggcacaa attctggact gcccactacc ctcccggccc tgtgccactc
721 cctgggctgg gaaacctgct gcaggtggac tttgagaaca tgccatatag cttatacaag
781 gtaagaaagg tggtggtgga gtacagtaga ggtcagaatg ccccaggtag catgtggtgt
841 tgctgaaggt aaagaaaaga caggaagatg gcccccaaga ggaaaaagtg ttgttgggaa
901 aacaaagtgg tgagaggggc cagctgtgct atagtctctt tctgctgtgt ggtctcaggc
961 ctggattccc atctcagaaa cctgaatttc ctctggtatg gtggagtagg aagggaccca
1021 aggaccttac tcaggctggg tctctgctga atgataatat ttgctatgag tcctttgcag
1081 agttgagaag atatgattgc caagctacaa ggtgacccaa ccacaggctg gggatgtaag
1141 tctgtgatag agcatttgcc cagcatatgt aggaacaagg ttcaataagt accatcatat
1201 acttgcacac acacacacac acacacacac acacacacag agttagagag agagagagaa
1261 agagagagag agagagagag agagagagag agagagagag agagatgggg ggtcagggac
1321 aaagacttgt gtgaggaacg tttatcttct gctagggaac attactacct atgtactctg
1381 tcccctattt cagcttcgaa gccgctatgg tgacgtgttc agcctacaga tagcctggaa
1441 gcctgtagtt gtgatcaacg ggctgaaggc cgtgcgggaa ctgctggtga cctatggaga
1501 ggacactgct gaccgccccc tactgcccat ctataatcac ctgggctatg ggaacaaatc
1561 aaaaggcaaa gcactatagt gtgggcaagg cagggagaat agggcttgag aggggagaac
1621 tgaagatggc tatggagata tgtggtcagg caattgaaga tggagggtgg agctgacagt
1681 gcagatatgt gctagaaaaa tgttggggac tgactgctaa cattaactac agggaagtgt
1741 tgggaacaga ggagacagca tagcccagna tccgtggtaa caccagatgc atctgcaggt
1801 gtggtccttg caccttacgg acctgagtgg cgagagcaga gacgattctc tgtgtccacc
1861 ctgcgtgact tcggcgtggg caagaaatcg ctggagcagt gggtgacaga ggaggccggc
1921 cacctctgtg acaccttcgc caaggaggct ggtaggtttg agatggagag tgtgggcaga
1981 gactaatgag caatgccatg acttgcttgc atctctgttc ctagaacatc ccttcaatcc
2041 cagcatcctc ctgagtaagg ctgtgagcaa cgtgattgcc tcccttgttt atgctcgtcg
2101 atttgagtat gaggaccctt tcttcaacag gatgctcaaa acattgaagg agagctttgg
2161 agaggacacc ggcttcatgg cagaggtatg tagctcagag cagcagacac gaccactcct
2221 gtgctgtaaa tcctttggag caagtatgaa tgaatccagg gtgtttgggg gtcagggcct
2281 cgggcgatag tcaattgcag ggagaaaggc ttgagcattg aagaacctca gataaactcg
2341 aggggacaag ccaaccaagg tcaatgattg cacaaaggtg gtaaacctct gccctctgtg
2401 cacagtgaaa ccacacaagc ctgttatatt tgaagagtag aatgtttctt tcttcactgg
2461 ggttcaagag agcaagcagg ctagaattga ggaagaagca gatgatgagt agggacaaat
2521 agaccctgag tccactgtgg aagaacacgg aaactgtgac tggtctaggg gaacactggg
2581 cagaaacagc agtcaggggc aaaagagata gatggtcagt gcgtaaagga gttcaccaag
2641 caagcctgga gacctgagct ggatccctga gtcccatata agggatagaa ctaactcttt
2701 aagttgatcc ctgaccatga aataatgagc cactacacac ctgggatact gtacctccaa
2761 gtacatgcac atgtgtgtgc acacacaatg acacatgaat aaaataatga attcttaatt
2821 agagctaaaa gcaactggac atgttttgtt tctttcacag gtgctgaacg caatcccaat
2881 tctccttcag attcctgggc tgcctggcaa agtcttcccc aagctcaatt catttatagc
2941 cttagtggat aagatgttaa ttgagcacaa gaaaagctgg gatcctgccc agccgccccg
3001 agacatgact gatgccttcc tagcagagat gcaaaaggtg attggaagct ccaagagatg
3061 tagccaggga ttgtgtgctg tggtcttctg agcagtgagg tcagatgtgt tcctctgtat
3121 cactaagtga ctcagtccct atgctcccaa ggaacaatag gaggccatga tgggacttcc
3181 tttccctact gaaccagccc tttctgcctg tccaggccaa ggggaatcct gagagcagct
3241 tcaatgatga aaatctgcgc ttggtggtga ttgacctgtt catggcgggg atggtgacca
3301 cctcaaccac actgtcctgg gcccttctgc tcatgatcct gcatccagat gtgcagcgtg
3361 agcctggctg tggatgggag ggaggtcagg ggaagaaagg cagaggtatt tgagaaacta
3421 gtggttcctg ccttagcttg acgtagtttc ccatgtgtct ggtatgagcc ctatctatct
3481 tactaaccca gtggtagaag ttgaaggatg agctcctttc gctgaagaga tgccatctat
3541 ctaggccgag tccacgagga gattgatgag gtcatagggc aggtgcgtcg tccagagatg
3601 gcagaccagg cacgaatgcc gttcaccaat gctgtcatcc atgaggtgca gcgctttgca
3661 gacatcgtcc cgacaaatat accacatatg acatcccgag acattaaatt ccaaggcttc
3721 ctcatcccca aggtaggcat acacactctg ttcccagaat ccacaatacg caaacaaggg
3781 aatggaatca acctgggtgt gagtacattg gagccattac ccaagatccc ctggagaaga
3841 ggacatccag tgaaatgagc tgtaggggtg gtaggaagag ctgcagatag gagctttgta
3901 acaagggttt gaatggacca gagaaggttc tgggaggctc tgggtttgag gtttaataaa
3961 aggatccagt gtgtaaggta gagacaatgc atgagaactt ggtggccagt gtctaggcag
4021 ctccaaccca gtccattttc acaccatatg ccctcttacc aggggacaac cctcatcccc
4081 aacctgtcct ccgtgctgaa ggatgagact gtctgggaga agcccctccg cttccatcca
4141 gaacacttcc tggatgccca gggcaacttt gtgaagcatg aggccttcat gccattctca
4201 gcaggtacct ctgggggggc tgactccctg tctattccca gggtgactgg gagggtggag
4261 ctccagtcag gccccagact gactgagctc ctgtcccacc acaggccgca gagcatgcct
4321 gggggagccc ctggcccgca tggagctctt cctcttcttc acctgcctcc tgcagcgctt
4381 cagcttctcg gtgctggccg gccggccccg gcccagcacc catggcgtct acgcattgcc
4441 agttactcca cagccttacc aactctgtgc agtggctcgc tagcaggggc aggggctcca
4501 ttcttctccc cggtttggtc tgattgatgt ccaataaaca acttctgtat cttcaaatca
4561 gattcccgat cccaccccca ccctggtccc aattgtatcc gaagacgaaa gtctacaatc
4621 ctccttgtcc ctctacgaca gcctaaccca tttacaactt taatgtggtg agaatagttt
4681 attactccag gagcagtggc cttcagtaaa gcaaagggag gatgatgcaa gtagattgca
4741 agtttaaggc aggcatgggg tatatataca gcctggacca cttaatgaga gcgtttctca
4801 acaagggggg gggtcgggat gggtgggtag tcatcatgga atgatgaagg gaggagggaa
4861 gaggcaatgg aatggaggag agagggaagc attcagataa agtaggagga gaggtagctg
4921 tgtggatggt ctctgcttca ccgtatatca cacaaaaaga cctatcgatg catgtgaaca
4981 gaagtcagac tcaagcaata ctgtgaggaa agtgtgaatg gcttatgcta gaaatcagca
5041 caagtcttgt tctggtgaca atgttggctg gcgtaggtcc ccaaaccctg aagagccaca
5101 aatggtggct agcacctctc tcataaccag aacagctgct gtcttcacac tcagactttc
5161 tgtcgtcaaa ggatgcggaa gacatctgca atagcaaaga ggcagatcag actccaggaa
5221 gatggtcagg gccccacagt tccatcggga cacctgtcca gacctagatg gctcgtccca
5281 caaccatgtg tggcgatgca ccgcatgcct ctcagtagga atgttcaagt gtttggaaga
5341 cgtgaaagcg tgtgtgtttg gtggggtgag ggaggactgt tctagaggca tgtgacactc
5401 tacaaggctc attttggcct ccataaaatc tgaggccagc ctacagcaac ccaagaccct
5461 gatgtatatt gcatgctttg aaagacacct gagtgcagac accgattttg agtttgcttt
5521 tgtgaaaaga aatgttctcc cacagacttc attttcatag ttatattaag gacactccca
5581 ccacagttcg tcattagcca cacaatggtc acacattagt caccacgatg gggaaattat
5641 atttcctgaa cccctccctt ttcctacaca agtaatcaca tctgtttacc acacactcca
5701 ccttgtccca cctctcccct tcatttttat tgtatatcca tgggtatttg cctgcaggtg
5761 tacactgtgt agagagaaca gaatagagca tcagatgccc aaggatttga gttctgtttt
5821 atatcatcct gtggatgctg ggagtgaagc ctgggccctc tggaagaaaa accagtgctc
5881 ttccctgctg aatgatctct tcagccctcc tattacccct ttctattggt gctggaaagt
5941 cttactctag tctgaagtaa tgtcctttag agccttatat ctctgcatgg tgcatgtcag
6001 atgagtaact catgatcatg caccttggag caggagtcca ctggacacgt atgcctttac
6061 tcacagttca cacaccaata ccagttcaca ccccctgtgg aatcagctct atatctcatg
6121 ccctccactg agtaagcacc agtcagggga tggatggaga agaagaggga aactaggagg
6181 cagaccttcc tagaggagtc tggcctctcc cagcaaccag actgagagaa agacaagagc
6241 tcaactcagg gcagaggata atagacagtc tttcctcctt tctaggggac cagatgccag
6301 gttgcagtaa gaggtctcct tcctgatctt tggaggttat tgtggttgat acaagatatt
6361 tccagaaaga actatgaata gtgatgtatc aattaggtaa ctgactgggg atgaaatggg
6421 ttcatgttct ggttgacctg atgcactgat ggcagttctg gaatccaaac caccagcagg
6481 accctcccat aacatacatg gcaacaggta gtgtgtgact tcagagagca tgttgtatga
6541 ttcataccca cagagagatg ggaaagaatg gcaacagaga tcatagcagc tgtagaaaca
6601 cactatggtt ctggagtcac aggacagaca ggggtctata ctccaagtag cagctttagc
6661 catttctgcc tgacaggcag gtcagggact gaggatactt tgcacttttg caacgcaaag
6721 tatgcacaga aagaccagga attgggccaa gacatgagag ctgacttggc cttggttgca
6781 caagtcagaa ggaatggaaa tgcaagtctt tctgcttcca ttaaaggatg ggttcttgat
6841 gtatggaaga gggaccaggg tcaatgtagc atttatacca agaattcaaa gggagacaca
6901 cactgtgtgc tctgggacct tgctgcctcc cacaagacac ctgactttat ttatacatag
6961 taggaggcta agaggcccaa tgtcagtttt caagccctgc taaggtcaca gctgggtagt
7021 catatctgag gtgatttaga agatgtgaca ttgctagcca caaggtctag atatcaggct
7081 gtggatgtag accagtgata aagcatttgt ccaacacttg tgaggacctg ggtataataa
7141 gtaccaaaca cgcacacatg gagtcttgtg tacgcagcct agttcttgaa gtctgatggg
7201 catttttgtt tgtttggttt tttgtttgtt tgtttgtttg tttgttttgg agatattctg
7261 acctctggcc ctatttaatt caacagtgga gagatgtgtc ccccttgcag gtgtctttta
7321 ggtagaggcc ctgatcaatg cacactgcag acgactctgg tacaaacaat ctaggcttcg
7381 tgcccagctc tgaagtcaag agctcatgtg ggccttggtt ggtcagagag gggcctggga
7441 cataggaagc aacagattag tgctaacttg cggtgctaca tgatctggtc atcaagccac
7501 agtcactgat ttcaaggaag aacacaaagg acatgtgcta gtgtttggcc acagcattat
7561 ggagaactca tggggggtac ttgatgcaga ggaacctact caaatggagg aatgtgggta
7621 acgcagagca gaacagctgg gtcttattgg ttagagccag actgtgagtg tacatgtgtc
7681 ttcttcccac attataagct t
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