GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS DROPTCR 5536 bp ss-mRNA INV 18-MAY-1991
DEFINITION D. melanogaster patched (ptc) mRNA involved in segment polarity
ACCESSION X17558
KEYWORDS developmental regulation; glycoprotein; patched gene;
segmentation gene; transmembrane protein.
SOURCE Drosophila melanogaster RNA.
ORGANISM Drosophila melanogaster
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (bases 1 to 5536)
AUTHORS Nakano,Y., Guerrero,I., Hidalgo,A., Taylor,A., Whittle,J.R. and
Ingham,P.W.
TITLE A protein with several possible membrane-spanning domains encoded
by the Drosophila segment polarity gene patched
JOURNAL Nature 341, 508-513 (1989)
STANDARD full automatic
REFERENCE 2 (bases 1 to 5536)
AUTHORS Ingham,P.W.
JOURNAL Unpublished (1990)
STANDARD full automatic
COMMENT *source: developmental stage=embryo; **map: chromosome=2; map
position=44D; **map: units=polytene chromosome interval; See also
M28418.
From EMBL 26 entry DMPTCR; dated 14-JAN-1991.
FEATURES Location/Qualifiers
mRNA 1..5536
/gene="ptc"
mat_peptide 752..4648
/standard_name="patched"
/note="signal peptide sequence was not determined"
/product="patched protein"
/gene="ptc"
CDS 752..4651
/standard_name="patched"
/product="patched protein"
/gene="ptc"
/codon_start=752
misc_feature 4896..4900
/note="mRNA destabilizing motif"
polyA_signal 4900..4905
/note="atypical"
misc_feature 5004..5008
/note="mRNA destabilizing motif"
misc_feature 5140..5144
/note="mRNA destabilizing motif"
misc_feature 5246..5250
/note="mRNA destabilizing motif"
misc_feature 5456..5460
/note="mRNA destabilizing motif"
polyA_signal 5503..5508
polyA_signal 5503..5508
polyA_site 5536..5536
BASE COUNT 1360 a 1575 c 1407 g 1194 t
ORIGIN
1 acagatacat ctctcagact gcgtgcgatc ctcgaacgaa acggttgtaa gtgcggagcg
61 cgacgacttg ttattcgtat ttccgactac tggcactctc tgtgtgtggt atactaacaa
121 gatagatatc acagaactcg tggaaaagct aagatattgt acctcacgga tgcgaggcga
181 agttcatgga ttaaatgcca ggcaacaaca aaagccagcc aaccagccag tgtttgtgtg
241 tgtgcgtcgc caagtgcaaa gtaaagtaaa ggtaaaagag cgaaaggcga gagagaaaac
301 cgaatacgtg agtcgtccga ctgccgcttt tccatgtgta aaagatctgt gaaaattctg
361 tcaaattccc ctgagaaatt gtgcccaaga taaaacccga aaaccgcgtt ttaatcgtcg
421 aaaaaaccca gcaaaagcga agccagcaat cacaacaaaa caacacaacg agagctcaga
481 tacacagcgt gctcagtgag tgagcgagag agcgcgggag agagcgtctc ttgatttaaa
541 atacaaaata attaaaaata aaaatgcgga gtgcagtgca aaatgcagcc aaacaaaata
601 cgagattcca ataacaatta atcgaaccga aagtccacga acaatccgca cactgtctcc
661 caagtctcag ttctcaggac gcagacgaac tcccatctgc acatctccgc cacgcgattc
721 cgtccggaat ctggctataa acataaccat aatggaccgc gacagcctcc cacgcgttcc
781 ggacacacac ggcgatgtgg tcgatgagaa attattctcg gatctttaca tacgcaccag
841 ctgggtggac gcccaagtgg cgctcgatca gatagataag ggcaaagcgc gtggcagccg
901 cacggcgatc tatctgcgat cagtattcca gtcccacctc gaaaccctcg gcagctccgt
961 gcaaaagcac gcgggcaagg tgctattcgt ggctatcctg gtgctgagca ccttctgcgt
1021 cggcctgaag agcgcccaga tccactccaa ggtgcaccag ctgtggatcc aggagggcgg
1081 cgggctggag gcggaactgg cctacacaca gaagacgatc ggcgaggacg agtcggccac
1141 gcatcagctg ctcattcaga cgacccacga cccgaacgcc tccgtcctgc atccgcaggc
1201 gctgcttgcc cacctggagg tcctggtcaa ggccaccgcc gtcaaggtgc acctctacga
1261 caccgaatgg gggctgcgcg acatgtgcaa catgccgagc acgccctcct tcgagggcat
1321 ctactacatc gagcagatcc tgcgccacct cattccgtgc tcgatcatca cgccgctgga
1381 ctgtttctgg gagggaagcc agctgttggg tccggaatca gcggtcgtta taccaggcct
1441 caaccaacga ctcctgtgga ccacactgaa tcccgcctct gtgatgcagt atatgaagca
1501 gaagatgtcc gaggaaaaga tcagcttcga cttcgagacc gtggagcagt acatgaagcg
1561 tgcggccatt gcgagtggct acatggagaa gccctgcctg aacccactga atcccaattg
1621 cccggacacg gcaccgaaca agaacagcac ccagccgccg gatgtgggag ccatcctgtc
1681 cggaggctgc tacggttatg ccgcgaagca catgcactgg ccggaggagc tgattgtggg
1741 cggagcgaag aggaaccgca gcggacactt gaggaaggcc caggccctgc agtcggtggt
1801 gcagctgatg accgagaagg aaatgtacga ccagtggcag gacaactaca aggtgcacca
1861 tcttggatgg acgcaggaga aggcagcgga ggttttgaac gcctggcagc gcaacttttc
1921 gcgggaggtg gaacagctgc tacgtaaaca gtcgagaatt gccaccaact acgatatcta
1981 cgtgttcagc tcggctgcac tggatgacat cctggccaag ttctcccatc ccagcgcctt
2041 gtccattgtc atcggcgtgg ccgtcaccgt tttgtatgcc ttctgcacgc tcctccgctg
2101 gagggacccc gtccgtggac agagcagtgt cggcgtggcc ggagttctgc tcatgtgctt
2161 tagtaccgcc gccggattgg gattgtcagc cctgctcggt atcgttttca atgccgccag
2221 cacccaggtg gttccgtttt tggcccttgg tctgggcgtc gatcacatct tcatgctgac
2281 cgctgcctat gcggagagca atcggcggga gcagaccaag ctgattctca agaaagtggg
2341 accgagcatc ctgttcagtg cctgcagcac cgcaggatcc ttctttgcgg ccgcctttat
2401 tccggtgccg gctttgaagg tattctgtct gcaggctgcc atcgtaatgt gctccaattt
2461 ggcagcggct ctattggttt ttccggccat gatttcgttg gatctacgga gacgtaccgc
2521 cggcagggcg gacatcttct gctgctgttt tccggtgtgg aaggaacagc cgaaggtggc
2581 accaccggtg ctgccgctga acaacaacaa cgggcgcggg gcccggcatc cgaagagctg
2641 caacaacaac agggtggcgc tgcccgccca gaatcctctg ctggaacaga gggcagacat
2701 ccctgggagc agtcactcac tggcgtcctt ctctctggca acattcgcct ttcagcacta
2761 cactcccttc ctcatgcgca gctgggtgaa gttcctgacc gttatgggtt tcctggcggc
2821 cctcatatcc agcttgtatg cctccacgcg ccttcaggat ggcctggaca ttattgatct
2881 ggtgcccaag gacagcaacg agcacaagtt cctggatgct caaactcggc tctttggctt
2941 ctacagcatg tatgcggtta cccagggcaa ctttgaatat cccacccagc agcagttgct
3001 cagggactac catgattcct ttgtgcgggt gccacatgtg atcaagaatg ataatggtgg
3061 actgccggac ttctggctgc tgctcttcag cgagtggctg ggtaatctgc aaaagatatt
3121 cgacgaggaa taccgcgacg gacggctgac caaggagtgc tggttcccaa acgccagcag
3181 cgatgccatc ctggcctaca agctaatcgt gcaaaccggc catgtggaca accccgtgga
3241 caaggaactg gtgctcacca atcgcctggt caacagcgat ggcatcatca accaacgcgc
3301 cttctacaac tatctgtcgg catgggccac caacgcgtct tcgcctacgg agcttctcag
3361 ggcaaattgt atccggaacc gcgccaacgg agcttctcag ggcaaattgt atccggaacc
3421 gcgccagtat tttcaccaac ccaacgagta cgatcttaag atacccaaga gtctgccatt
3481 ggtctacgct cagatgccct tttacctcca cggactaaca gatacctcgc agatcaagac
3541 cctgataggt catattcgcg acctgagcgt caagtacgag ggcttcggcc tgcccaacta
3601 tccatcgggc attcccttca tcttctggga gcagtacatg accctgcgct cctcactggc
3661 catgatcctg gcctgcgtgc tactcgccgc cctggtgctg gtctccctgc tcctgctctc
3721 cgtttgggcc gccgttctcg tgatcctcag cgttctggcc tcgctggccc agatctttgg
3781 ggccatgact ctgctgggca tcaaactctc ggccattccg gcagtcatac tcatcctcag
3841 cgtgggcatg atgctgtgct tcaatgtgct gatatcactg ggcttcatga catccgttgg
3901 caaccgacag cgccgcgtcc agctgagcat gcagatgtcc ctgggaccac ttgtccacgg
3961 catgctgacc tccggagtgg ccgtgttcat gctctccacg tcgccctttg agtttgtgat
4021 ccggcacttc tgctggcttc tgctggtggt cttatgcgtt ggcgcctgca acagcctttt
4081 ggtgttcccc atcctactga gcatggtggg accggaggcg gagctggtgc cgctggagca
4141 tccagaccgc atatccacgc cctctccgct gcccgtgcgc agcagcaaga gatcgggcaa
4201 atcctatgtg gtgcagggat cgcgatcctc gcgaggcagc tgccagaagt cgcatcacca
4261 ccaccacaaa gaccttaatg atccatcgct gacgacgatc accgaggagc cgcagtcgtg
4321 gaagtccagc aactcgtcca tccagatgcc caatgattgg acctaccagc cgcgggaaca
4381 gcgacccgcc tcctacgcgg ccccgccccc cgcctatcac aaggccgccg cccagcagca
4441 ccaccagcat cagggcccgc ccacaacgcc cccgccgccc ttcccgacgg cctatccgcc
4501 ggagctgcag agcatcgtgg tgcagccgga ggtgacggtg gagacgacgc actcggacag
4561 caacaccacc aaggtgacgg ccacggccaa catcaaggtg gagctggcca tgcccggcag
4621 ggcggtgcgc agctataact ttacgagtta gcactagcac tagttcctgt agctattagg
4681 acgtatcttt agactctagc ctaagccgta accctatttg tatctgtaaa atcgatttgt
4741 ccagcgggtc tgctgaggat ttcgttctca tggattctca tggattctca tggatgctta
4801 aatggcatgg taattggcaa aatatcaatt tttgtgtctc aaaaagatgc attagcttat
4861 ggtttcaaga tacattttta aagagtccgc cagatattta tataaaaaaa tccaagatca
4921 cgtatccatg aaaattgaaa agctaagcag acccgtatgt atgtatatgt gtatgcatgt
4981 tagttaattt cccgaagtcc ggtatttata gcagctgcct tccccgcccc ccttcccttg
5041 aaatgaacac ccttccagcc acgccccacc gcccctctgc gtagcagctt tgtatgtatg
5101 tagtatgcta gcacctaagg aatacttaaa cttagagata tttattgtaa cacacgcaaa
5161 acacacacaa tgtacttaca tataattcaa tgcgagattc acccacacaa aaaggaaaca
5221 cacaaactag taattgtagc tcgtaattta gtttagttta aatatgtaca taaacacagg
5281 acttgaccaa atagtatcgc ttaaacggaa acgagagaaa cgagaaaaaa taactattac
5341 ttaatcaact acaagagaga tatccctcct cccctaaccg tacttacaac caaaataaaa
5401 caagagtata agcataaaaa tggaaaacga agcgaggaac gattgtaaac gcggcattta
5461 tccatgtaca tttgttgcac gaagactgac tgtctttttt ttaataaaaa tatatattat
5521 acagttttta aaagcg
//