GenBank-Updates@genbank.bio.net (05/18/91)
LOCUS DROADH01 4607 bp ds-DNA INV 18-MAY-1991
DEFINITION Drosophila simulans gene for alcohol dehydrogenase
ACCESSION X00607 X03226 Z00031
KEYWORDS alcohol dehydrogenase.
SOURCE Drosophila simulans DNA.
ORGANISM Drosophila simulans
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (sites)
AUTHORS Cohn,V.H., Thompson,M.A. and Moore,G.P.
TITLE Nucleotide sequence comparison of the Adh gene in three
drosophilids
JOURNAL J. Mol. Evol. 20, 31-37 (1984)
STANDARD full staff_review
REFERENCE 2 (bases 1100 to 3278)
AUTHORS Bodmer,M. and Ashburner,M.
TITLE Conservation and change in the DNA sequences coding for alcohol
dehydrogenase in sibling species of Drosophila
JOURNAL Nature 309, 425-430 (1984)
STANDARD full automatic
REFERENCE 3 (bases 1 to 4607; 1100 to 3278)
AUTHORS Cohn,V.H.
JOURNAL Unpublished (1985)
STANDARD full automatic
COMMENT EPD; 14018; Ds ADH adult E1. EPD; 14022; Ds ADH larva E2.
SWISS-PROT; P07163; ADH$DROSI.
Differences between the Bodmer and Cohen sequences shown as
Conflicts in FT, but may well be allelic differences. None affect
protein.
From EMBL 26 entry DSADH01; dated 05-DEC-1990.
FEATURES Location/Qualifiers
CDS join(2104..2202,2270..2674,2744..3007)
/product="alcohol dehydrogenase"
/codon_start=2104
conflict 1123..1123
/note="G in [3]"
conflict 1124..1124
/note="T in [3]"
conflict 1126..1126
/note="G in [3]"
conflict 1128..1128
/note="C in [3]"
conflict 1171..1171
/note="C in [3]"
conflict 1184..1184
/note="G in [3]"
conflict 1249..1249
/note="C in [3]"
promoter 1293..1298
/note="adult TATA-box"
conflict 1309..1309
/note="A in [3]"
mRNA 1325..1411
/note="adult exon"
misc_feature 1325..1325
/note="adult mRNA 5' end"
conflict 1386..1386
/note="T in [3]"
intron 1412..2067
/note="adult intron"
conflict 1429..1429
/note="A in [3]"
conflict 1430..1430
/note="C in [3]"
conflict 1457..1457
/note="C in [3]"
conflict 1458..1458
/note="G in [3]"
conflict 1500..1500
/note="A in [3]"
conflict 1501..1501
/note="G in [3]"
conflict 1512..1512
/note="G in [3]"
conflict 1516..1516
/note="deleted in [3]"
conflict 1518..1518
/note="deleted in [3]"
conflict 1521..1521
/note="deleted in [3]"
conflict 1527..1527
/note="C in [3]"
conflict 1528..1528
/note="T in [3]"
conflict 1557..1557
/note="T in [3]"
conflict 1558..1558
/note="C in [3]"
conflict 1561..1561
/note="G in [3]"
conflict 1568..1568
/note="G in [3]"
conflict 1570..1570
/note="G in [3]"
conflict 1596..1596
/note="A in [3]"
conflict 1603..1603
/note="A in [3]"
conflict 1620..1620
/note="C in [3]"
conflict 1923..1923
/note="T in [3]"
promoter 2002..2007
/note="larval TATA-box"
conflict 2011..2011
/note="deleted in [3]"
misc_feature 2034..2034
/note="larval mRNA 5' end"
conflict 2084..2084
/note="A in [3]"
intron 2203..2269
/note="intron I"
conflict 2256..2256
/note="C in [3]"
conflict 2278..2278
/note="G in [3]"
conflict 2302..2302
/note="T in [3]"
conflict 2599..2599
/note="A in [3]"
intron 2675..2743
/note="intron II"
conflict 2696..2696
/note="A in [3]"
conflict 2708..2711
/note="deleted in [3]"
conflict 2941..2941
/note="C in [3]"
polyA_site 3181..3181
/note="polyadenylation site"
conflict 3245..3245
/note="deleted in [3]"
conflict 3253..3253
/note="deleted in [3]"
conflict 3259..3259
/note="deleted in [3]"
BASE COUNT 1367 a 1022 c 949 g 1269 t
ORIGIN
1 gaattcttaa gcgtctccaa agcttccaga gaactgggcc atatatgacc cgatatctgt
61 atatatacat atatatattt tagcaaatat attttccaat taggtgaaag aacttgtgtg
121 catacacaca tatagtttta tatcaacaaa caggtttaag ttttatgcaa attgaaagct
181 tatttcttcc gcatgcttat ctctttcctt ctcatcatat gtatgtgata ttgcagtagc
241 ctcctcccac atcacattta acgccctata ttcacaattt gctcaagaaa atatttgaaa
301 ccaaattgat ttctagtcaa ttagttttta aggcgctgtg tgtcagctta aaaaatgcaa
361 attaagtgag taaaaatata aacttttaat tcttgctaaa catatataca catatatttt
421 taataaataa actacgaata tataaagact acgaagctgg aaaacaaatt taaaaatgaa
481 gcattatagt attttcggtt taatatatac atatgtatta atctaatgtg cgagcatggg
541 ttaaatctag ctgcatttga aaccgctact ctggctcggc acaaagtggg cttggtcgca
601 gttgcggaca agtgagattg ctaatgagct gcttttaggg ggcgtgttgt gcttgctttc
661 caacttttct agattgattc tacgctgcct ccagcaggca cccctcccat caccatcccc
721 atcgccatcc cccatcacca tccagtcccg ctggtcccca gtcacagtat tacacgtatg
781 caaattaagc cgaagttcaa ttgcgaccgc agcaacaaca cgagctcgga tctttctaca
841 cttctccttg ctatgcttga cattcacaag gtcaaagctc ttagtattct gactcggggt
901 ccaaacactg taaaaaatta ctctagaaat aacggtacac ttaatatgat tttattttaa
961 tccatatgcc aaatatgtta tgtatgttta tgttatatta ttgttaggaa accaatgttt
1021 ttttaaatcg gttaaaaagt tgctactaga aaaacataaa catttttgga atatttttga
1081 atattttcat cattttgtgt ttttacgttt tactcatttt tttctcagtg cactttctgg
1141 tgttccattt tctattgggc tccttacccg ccatttgttt gcaaatcact tgcttgcgca
1201 tttttattgc attttacata ttacaaatta tttttacgcc gctgctgctg ccgccgtcga
1261 cgtcgactgc actcgccccc acgacagaac agtatttaag gagctgcgga ggtccaagtc
1321 gccgattatt gtctcagtgc agttgtcagt tgcagttcag cagaccggct aacgagtact
1381 tgcatctctt caaatttact taattgatca agtaagtagc aaaagggcga ccaattgaag
1441 gaaattcttg tttaatttaa tttattatgc aagtgcggaa ataaaatgac agtattaaac
1501 agaaaataaa ttttgctaaa actcataaaa tcaaatttat tcaatcaaaa ttaattcaaa
1561 ctgtcacaaa tagtgtgaac tcaattaatt ggcatctaat tagaatttgg aggcctgtgt
1621 cgaatattcg tcttggaaaa tcacctgtta gttaacttct aaaaatagga attttaacat
1681 aacccgcccc tgttaatcgg cgccgtgcct tcgttagcta tctcaaaagc gagcgcgtgc
1741 agacgagcag taattttcca agcatcaggc atagttgggc ataaattata aacatacaaa
1801 ccgaatacta atatagaaaa agctttgccg gtacaaaatc ccaaacaaaa acaaaccgtg
1861 tgtgccgaaa aataaaaata aaccataaac taggcagcgc tgccgtcgcc ggctgagcag
1921 cccgcgtaca tagccgagat cgcgtaacgg tagataatga aaagctctac gtaaccgaag
1981 cttctgcggt acggatcttc ctataaatac ggggccgaca cgaactggaa accaacaact
2041 aacggagccc tcttcccatt gaaacagatc gaaagagcct gcttaagcaa aaaagaagtc
2101 accatggcgt ttactttgac caacaagaac gtgattttcg ttgccggtct gggaggcatc
2161 ggtctggaca ccagcaagga gctgctcaag cgcgacctga aggtaactat gcgatgccca
2221 caggctccat ggagggggat tgaggttaat ctcgtgtatt caatcctaga acctggtaat
2281 cctcgaccgc attgagaacc cggctgccat tgccgagctg aaggcaatca atccaaaggt
2341 gaccgtcacc ttctacccct atgatgtgac cgtgcccatt gccgagacca ccaagctgct
2401 gaagaccatc ttcgccaagc tgaagaccgt cgatgtcctg atcaacggag ctggtatcct
2461 ggacgatcac cagatcgagc gcaccattgc cgtcaactac actggcctgg tcaacaccac
2521 gacggccatt ctggacttct gggacaagcg caagggtggt cccggtggta tcatctgcaa
2581 cattggatcc gtcactggtt tcaatgccat ctaccaggtg cccgtctact ccggcaccaa
2641 ggccgccgtg gtcaacttca ccagctccct ggcggtaagt tcatcgaagg aaacgcaaag
2701 ttttcaaaaa ataaaaaact aatttgtttt ataacacctt tagaaactgg cccccattac
2761 cggcgtgacc gcttacaccg tgaaccccgg catcacccgc accaccctgg tgcacaagtt
2821 caactcctgg ctggatgttg agccccaggt tgccgagaag ctcctggctc atcccaccca
2881 gccctcgttg gcctgcgccg agaacttcgt caaggctatc gagctgaacc agaacggagc
2941 gatctggaaa ctggacttgg gcaccctgga ggccatccag tggaccaagc actgggactc
3001 cggcatctaa gaagtgatac tcccaagaaa cacataacat tagttcatag ggttctgcga
3061 accacaagat attcacgcaa ggcaataagg ctgattcgaa gcacactcac attcttcccc
3121 taatacgata ataaaactct ccatgaaaaa tatggaaaaa tatatgaaaa ttgagaaatc
3181 caaaaaactg ataaacgctc tacttaatta aaatagataa atgggagcgg ctggaatggc
3241 ggaacatggc caagttcctc cgccaatcag tcgtaaaaca gaagtcgtgg aaagcggata
3301 gaaagaatgt tcgatttgac gagcaagcat gtctgctatg tggcggattg cggaggaatt
3361 gcactggaga ccagcaaggt tctcatgacc aagaacatag cggtgagtga gcgggaagct
3421 gacggctttg gggttcggtt tctgtccaga tcgaactcaa aactagtcca gccagtcgct
3481 gtcgaaacta attaagttaa tgagtttttc atgtttgttt cgcgctgagc aacaattaag
3541 tttatgtttc agttcagttt tgatgaagga cttggcactt tcaatgaata ctttagaaca
3601 aaagcacaac tcattctaat aacttggtgg tcatattttt tttaatgata agtttaaact
3661 ttttatattt cgatattaaa ccacctatga agtctatttt aatcgccaga taagccatat
3721 atactgcgta aatatttgta ttctttatca ggaaattcag agaaacgggg aatttactat
3781 ctactaaaag ccaaacaatt tcttacagtt ttactctctc cactctagaa attggccatt
3841 ttacagagca cggaaaatcc ccaggccatc gctcagctgc agtcgataaa accgagtacc
3901 caaatatttt tctggaccta cgacgtgacc atggcaaggg aagaaatgaa gaagtacttc
3961 gatgaggtga tggtccaaat ggactacatc gatgtcctga tcaatggagc tacgctgtgc
4021 gatgaaaata acattgatgc caccatcaat acaaatctaa cgggaatgat gaacactgtg
4081 gccacggtat taccctatat ggacagaaaa atgggaggat ctggtgggct aattgtgaac
4141 gttacctccg tcattggatt ggacccttcg ccggttttct gcgcatatag tgcatccaag
4201 ttcggtgtga ttggatttac cagaagtcta gcggtgaatt gaatccaatc ttatcgggat
4261 aaattcttta atttttgctt tttaggaccc cctttactat tcccaaaacg gagtcgctgt
4321 gatggcggtt tgttgtggtc ccacaagggt ctttgtggac cggaaactga aagcgttttt
4381 ggaatacgga caatcctttg ccgatcgcct gcgtcgagct ccctgccaat cgacatcggt
4441 gtgtggtcag aatattgtca atgccatcga gagatcggag aatggccaga tatggattgc
4501 ggataagggt ggactggagt tggtcaaatt gcattggtac tggcacatgg ccgaccagtt
4561 cgtgcactat atgcagagca atgatgaaga ggatcaagat tgaattc
//